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The map label for this gene is mdtI

Identifier: 85058607

GI number: 85058607

Start: 1074276

End: 1074605

Strand: Reverse

Name: mdtI

Synonym: SG0629

Alternate gene names: 85058607

Gene position: 1074605-1074276 (Counterclockwise)

Preceding gene: 85058608

Following gene: 85058606

Centisome position: 25.76

GC content: 54.24

Gene sequence:

>330_bases
ATGCAACAGTTTGATCTCTATCACTCCGGTTTCCTAGCGTCGGCGGTGGTATTGGAAATTTTGGCCAACATTTTGCTCAA
AATGTCGGACGGTTTTCGTAAATTGTGGCTGGGCCTGCTCTCGCTCTTGGCGGTACTCGGCGCTTTCAGCGCCCTGTCAC
AGGCTGTCAAAGGCATCGATCTTTCCGTCGCCTATGCGCTTTGGGGGGGGTTTGGCATCGCCGCGACCATCGCCGCCGGC
TGGATAATGTTTAATCAGCGCTTGAGCAGCCGCGGTTGGGCTGGTCTGGTATTGTTGCTCATCGGCATGTTGGTGATAAA
GTTGGCGTAA

Upstream 100 bases:

>100_bases
GGGCTGGCCATTTTAGTCATCGGCATTGTGATGCTGAAATCCGGCACCCGTAAAGCGCAGGGCGATAGCGGTCTGAAAGC
GCGGCAGAAGGAGCGCCATC

Downstream 100 bases:

>100_bases
CCCAGGATGACGCCCGACGGCCAAAGGTCATTTTTCTTTGGCATCCCCTGTCACAGGACTCTTTTTTTACCCCCGTTTTA
TTCGCTCGTGGATTTTATTT

Product: multidrug efflux system protein MdtI

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 109; Mature: 109

Protein sequence:

>109_residues
MQQFDLYHSGFLASAVVLEILANILLKMSDGFRKLWLGLLSLLAVLGAFSALSQAVKGIDLSVAYALWGGFGIAATIAAG
WIMFNQRLSSRGWAGLVLLLIGMLVIKLA

Sequences:

>Translated_109_residues
MQQFDLYHSGFLASAVVLEILANILLKMSDGFRKLWLGLLSLLAVLGAFSALSQAVKGIDLSVAYALWGGFGIAATIAAG
WIMFNQRLSSRGWAGLVLLLIGMLVIKLA
>Mature_109_residues
MQQFDLYHSGFLASAVVLEILANILLKMSDGFRKLWLGLLSLLAVLGAFSALSQAVKGIDLSVAYALWGGFGIAATIAAG
WIMFNQRLSSRGWAGLVLLLIGMLVIKLA

Specific function: Catalyzes the excretion of spermidine

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. MdtI subfamily

Homologues:

Organism=Escherichia coli, GI1787883, Length=109, Percent_Identity=72.4770642201835, Blast_Score=136, Evalue=3e-34,
Organism=Escherichia coli, GI1786755, Length=98, Percent_Identity=32.6530612244898, Blast_Score=61, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MDTI_SODGM (Q2NVC1)

Other databases:

- EMBL:   AP008232
- RefSeq:   YP_454309.1
- STRING:   Q2NVC1
- GeneID:   3868448
- GenomeReviews:   AP008232_GR
- KEGG:   sgl:SG0629
- NMPDR:   fig|343509.6.peg.1381
- eggNOG:   COG2076
- HOGENOM:   HBG740972
- OMA:   AGWIMFN
- PhylomeDB:   Q2NVC1
- ProtClustDB:   PRK10650
- BioCyc:   SGLO343509:SG0629-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_01597
- InterPro:   IPR000390

Pfam domain/function: PF00893 Multi_Drug_Res

EC number: NA

Molecular weight: Translated: 11668; Mature: 11668

Theoretical pI: Translated: 10.23; Mature: 10.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xdd6fbf4)-; HASH(0xdcacf6c)-; HASH(0xdc81928)-; HASH(0xdca9400)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQFDLYHSGFLASAVVLEILANILLKMSDGFRKLWLGLLSLLAVLGAFSALSQAVKGID
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
LSVAYALWGGFGIAATIAAGWIMFNQRLSSRGWAGLVLLLIGMLVIKLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MQQFDLYHSGFLASAVVLEILANILLKMSDGFRKLWLGLLSLLAVLGAFSALSQAVKGID
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
LSVAYALWGGFGIAATIAAGWIMFNQRLSSRGWAGLVLLLIGMLVIKLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA