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The map label for this gene is surA

Identifier: 85058404

GI number: 85058404

Start: 747954

End: 749249

Strand: Reverse

Name: surA

Synonym: SG0426

Alternate gene names: 85058404

Gene position: 749249-747954 (Counterclockwise)

Preceding gene: 85058405

Following gene: 85058403

Centisome position: 17.96

GC content: 58.95

Gene sequence:

>1296_bases
ATGAAAAACTGGAGAACGTTTATCCTCGGCCTCGCCCTGTGCGCCAACGGCGCGCTCGCCGCGCCGCAGGTTGTGGATAA
AGTTGCCGCCGTGGTGGACAACGGCATCGTCCTGGAAAGCGAAGTGGACAATATGCTGTCCACGGTGAAACACGGCGCTC
AGGAAGCCAACCAACAGCTGCCGGACGACACGACGCTACGCCGCCAGATCCTCGACCGGCTGATTATGGATAACATCATT
TTGCAGCTGGCCCAGCGCACCAATATCACCATCAGCGACGAGCAGCTGGATCAGGCCATCGGCAATATCGCCGCCCAGAA
CCATATGTCACTCGATCAGCTGCGCAGCCGCCTGCCCTATGACGGCATAGACTACAACACATATCGCACGCAAATCCGCA
AAGAGATGCTGATTGCCGAAGTGCGTAACGGCGAAGTCCGCCGTCGCGTCACCATCTTGCCGCAGGAAGTCGAGTCGCTG
GCGCAACAAATTGCCGCCCAGACCGGCAACGGCGCCGAATTCAATCTCAGCCATATCCTCATCCCGTTACCGGAAAACCC
GACGCAGGATCAACTGGACAAAGCGGAAGAACTGGCCACCTCAATTGTCGAGCAAAGCAAAAGCGGCGCCGACTTCGGAA
AGTTGGCAATTACTTACTCCGCCGATGCCCAGGCGCTGAAAGGCGGCCAGATGGGCTGGGGGAAACTAGAAGAGCTCCCA
TCGCTGTTCGCGGCGCGCCTTCAGGGCGCTCAAAAGGGCAGCATTGTCGGCCCGATTCGTTCCGGCGTCGGCTTCCATAT
TCTGAAAGTTAACGACATCCGCGGCGGCGATCAGAAAGTGGCGGTCACCGAAGTACATGCGCGCCATATTATGCTGCGCA
CCTCGGTCGTGATGACCGACCAGCAGGCCCGCGCCAAGCTTGAAGATATCGCGGCGCAAATCAAGAGCGGACGTATCAGC
TTCGCCGCCGCCGCCAAACAGCTGTCCGAAGATCCGGGCTCGGCAAATCAGGGCGGCGATCTGGGCTGGAGCTCAGCCGA
TGCCTTCGATCCAGCGTTCCGCAACGCGCTGATGCACCTGAAGAAAGGGGAAATCAGTACGCCGGTGCACTCCTCCTTCG
GCTGGCATCTGATTCAGCTTATCGACACCCGCCAGGTGGACCGTACCGACGCTGCCCAGAAAGATCGCGCCTACCGGCTG
CTGTTTAACCGCAAGTTTGCTGAAGAGGCGCAAACCTGGATGCAGGAGCAGCGCGCGTCCGCTTACGTGAAAATCCTCGA
TAGCAATGGGCAGTAA

Upstream 100 bases:

>100_bases
GCCTCCGGCATTCTGCCCTATCAGCGGGCGTTCTAAGCTGCAGTCTCGACGCAAACATTGAACTTAATCCGCATATGCGG
CTGATATATATGGAAAAGTT

Downstream 100 bases:

>100_bases
TCAACGCATTGTCATCACCCCCGGCGAACCCGCCGGGATTGGTCCGGACCTTGTCGCCGCGCTGGCCCAGCAGGCGTGGC
CGGTTGAACTGGTCATTTGC

Product: peptidyl-prolyl cis-trans isomerase SurA

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase surA; PPIase surA; Rotamase surA

Number of amino acids: Translated: 431; Mature: 431

Protein sequence:

>431_residues
MKNWRTFILGLALCANGALAAPQVVDKVAAVVDNGIVLESEVDNMLSTVKHGAQEANQQLPDDTTLRRQILDRLIMDNII
LQLAQRTNITISDEQLDQAIGNIAAQNHMSLDQLRSRLPYDGIDYNTYRTQIRKEMLIAEVRNGEVRRRVTILPQEVESL
AQQIAAQTGNGAEFNLSHILIPLPENPTQDQLDKAEELATSIVEQSKSGADFGKLAITYSADAQALKGGQMGWGKLEELP
SLFAARLQGAQKGSIVGPIRSGVGFHILKVNDIRGGDQKVAVTEVHARHIMLRTSVVMTDQQARAKLEDIAAQIKSGRIS
FAAAAKQLSEDPGSANQGGDLGWSSADAFDPAFRNALMHLKKGEISTPVHSSFGWHLIQLIDTRQVDRTDAAQKDRAYRL
LFNRKFAEEAQTWMQEQRASAYVKILDSNGQ

Sequences:

>Translated_431_residues
MKNWRTFILGLALCANGALAAPQVVDKVAAVVDNGIVLESEVDNMLSTVKHGAQEANQQLPDDTTLRRQILDRLIMDNII
LQLAQRTNITISDEQLDQAIGNIAAQNHMSLDQLRSRLPYDGIDYNTYRTQIRKEMLIAEVRNGEVRRRVTILPQEVESL
AQQIAAQTGNGAEFNLSHILIPLPENPTQDQLDKAEELATSIVEQSKSGADFGKLAITYSADAQALKGGQMGWGKLEELP
SLFAARLQGAQKGSIVGPIRSGVGFHILKVNDIRGGDQKVAVTEVHARHIMLRTSVVMTDQQARAKLEDIAAQIKSGRIS
FAAAAKQLSEDPGSANQGGDLGWSSADAFDPAFRNALMHLKKGEISTPVHSSFGWHLIQLIDTRQVDRTDAAQKDRAYRL
LFNRKFAEEAQTWMQEQRASAYVKILDSNGQ
>Mature_431_residues
MKNWRTFILGLALCANGALAAPQVVDKVAAVVDNGIVLESEVDNMLSTVKHGAQEANQQLPDDTTLRRQILDRLIMDNII
LQLAQRTNITISDEQLDQAIGNIAAQNHMSLDQLRSRLPYDGIDYNTYRTQIRKEMLIAEVRNGEVRRRVTILPQEVESL
AQQIAAQTGNGAEFNLSHILIPLPENPTQDQLDKAEELATSIVEQSKSGADFGKLAITYSADAQALKGGQMGWGKLEELP
SLFAARLQGAQKGSIVGPIRSGVGFHILKVNDIRGGDQKVAVTEVHARHIMLRTSVVMTDQQARAKLEDIAAQIKSGRIS
FAAAAKQLSEDPGSANQGGDLGWSSADAFDPAFRNALMHLKKGEISTPVHSSFGWHLIQLIDTRQVDRTDAAQKDRAYRL
LFNRKFAEEAQTWMQEQRASAYVKILDSNGQ

Specific function: Chaperone involved in the correct folding and assembly of outer membrane proteins. It recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasm. Note=Is capable of associating with the outer membrane (By similarity)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PpiC domains

Homologues:

Organism=Escherichia coli, GI1786238, Length=426, Percent_Identity=70.6572769953052, Blast_Score=629, Evalue=0.0,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): SURA_SODGM (Q2NVX4)

Other databases:

- EMBL:   AP008232
- RefSeq:   YP_454106.1
- HSSP:   P24327
- ProteinModelPortal:   Q2NVX4
- SMR:   Q2NVX4
- STRING:   Q2NVX4
- GeneID:   3867537
- GenomeReviews:   AP008232_GR
- KEGG:   sgl:SG0426
- NMPDR:   fig|343509.6.peg.990
- eggNOG:   COG0760
- HOGENOM:   HBG391483
- OMA:   RHILIKT
- PhylomeDB:   Q2NVX4
- ProtClustDB:   PRK10770
- BioCyc:   SGLO343509:SG0426-MONOMER
- HAMAP:   MF_01183
- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR023034
- InterPro:   IPR015391
- InterPro:   IPR008880
- Gene3D:   G3DSA:1.10.3120.10

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N; SSF109998 Trigger_fac_C_bac

EC number: =5.2.1.8

Molecular weight: Translated: 47422; Mature: 47422

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS01096 PPIC_PPIASE_1; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNWRTFILGLALCANGALAAPQVVDKVAAVVDNGIVLESEVDNMLSTVKHGAQEANQQL
CCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHCC
PDDTTLRRQILDRLIMDNIILQLAQRTNITISDEQLDQAIGNIAAQNHMSLDQLRSRLPY
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHHHCCCCHHHHHHHCCC
DGIDYNTYRTQIRKEMLIAEVRNGEVRRRVTILPQEVESLAQQIAAQTGNGAEFNLSHIL
CCCCCHHHHHHHHHHHHHHHHCCCCHHHHEEECHHHHHHHHHHHHHCCCCCCEEEEEEEE
IPLPENPTQDQLDKAEELATSIVEQSKSGADFGKLAITYSADAQALKGGQMGWGKLEELP
EECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHCCCCCCCHHHHHHH
SLFAARLQGAQKGSIVGPIRSGVGFHILKVNDIRGGDQKVAVTEVHARHIMLRTSVVMTD
HHHHHHHCCCCCCCEECHHHCCCCEEEEEEECCCCCCCEEEEEHHHHHHHHHHHHHHCCC
QQARAKLEDIAAQIKSGRISFAAAAKQLSEDPGSANQGGDLGWSSADAFDPAFRNALMHL
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
KKGEISTPVHSSFGWHLIQLIDTRQVDRTDAAQKDRAYRLLFNRKFAEEAQTWMQEQRAS
HCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AYVKILDSNGQ
HEEEEECCCCC
>Mature Secondary Structure
MKNWRTFILGLALCANGALAAPQVVDKVAAVVDNGIVLESEVDNMLSTVKHGAQEANQQL
CCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHCC
PDDTTLRRQILDRLIMDNIILQLAQRTNITISDEQLDQAIGNIAAQNHMSLDQLRSRLPY
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHHHCCCCHHHHHHHCCC
DGIDYNTYRTQIRKEMLIAEVRNGEVRRRVTILPQEVESLAQQIAAQTGNGAEFNLSHIL
CCCCCHHHHHHHHHHHHHHHHCCCCHHHHEEECHHHHHHHHHHHHHCCCCCCEEEEEEEE
IPLPENPTQDQLDKAEELATSIVEQSKSGADFGKLAITYSADAQALKGGQMGWGKLEELP
EECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHCCCCCCCHHHHHHH
SLFAARLQGAQKGSIVGPIRSGVGFHILKVNDIRGGDQKVAVTEVHARHIMLRTSVVMTD
HHHHHHHCCCCCCCEECHHHCCCCEEEEEEECCCCCCCEEEEEHHHHHHHHHHHHHHCCC
QQARAKLEDIAAQIKSGRISFAAAAKQLSEDPGSANQGGDLGWSSADAFDPAFRNALMHL
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
KKGEISTPVHSSFGWHLIQLIDTRQVDRTDAAQKDRAYRLLFNRKFAEEAQTWMQEQRAS
HCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AYVKILDSNGQ
HEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA