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The map label for this gene is kdsC [H]

Identifier: 85058181

GI number: 85058181

Start: 381967

End: 382530

Strand: Reverse

Name: kdsC [H]

Synonym: SG0203

Alternate gene names: 85058181

Gene position: 382530-381967 (Counterclockwise)

Preceding gene: 85058182

Following gene: 85058180

Centisome position: 9.17

GC content: 59.22

Gene sequence:

>564_bases
ATGCAAGAGACCCCCACCGTCGAGACATGCTACGGACCGGTAGCGCAGCAGGTGCTGGAAAGCGCCCGGACTATTCGTCT
GCTGATTTGCGATGTAGATGGCGTCATGTCCGACGGTCTGATTTATATGGGCAATCACGGTGAAGAACTCAAAACGTTTA
ATGTCCGCGATGGCTACGGCATTCGCTGCCTGCTGACATCGGGCATTGAGGTCGCTATTATTACCGGCCGCTCCGCCAGG
CTGCTGGAGGACCGTTGCACCACGCTAGGCATTACGCATATTTACCAGGGGCAATCGGATAAGACTTTGGCCTTTAGAGC
GCTTCTGAGTAAACTGAAGTTAACGGCGGAACAGGTCGCCTACGTGGGCGACGACCTGATTGATGCCCCGGTCATGGACC
AGGTCGGCCTGAGCGTGGCGGTGGCGGATGCGCACCCGCTATTGCGGCCCAGGGCCGATTATGTTACCCGCATCGCCGGC
GGCCGCGGCGCGGTGCGGGAAGTCTGCGACCTGCTGCTGCTGGCGCAGGGAAAGCTGGAGGATGCCAAAGGGCAGTCGTT
ATGA

Upstream 100 bases:

>100_bases
ACATTACTTCGCTAATGGTGGCGCAGGACGACCATCTGTTAGGCGTAGTGCATATGCATGATATGCTACGCGCCGGCGTG
ATATAACAAGGAATAACGTC

Downstream 100 bases:

>100_bases
GCAAGACAACGCGTTGGACCACGGCGCTGCTGGGATTATTGGTATTAGTGCTTATCGGCTGGAATTTGGCGGACACCGAC
ACGGCGCCGGCCCAGACGCC

Product: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase

Products: NA

Alternate protein names: KDO 8-P phosphatase [H]

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MQETPTVETCYGPVAQQVLESARTIRLLICDVDGVMSDGLIYMGNHGEELKTFNVRDGYGIRCLLTSGIEVAIITGRSAR
LLEDRCTTLGITHIYQGQSDKTLAFRALLSKLKLTAEQVAYVGDDLIDAPVMDQVGLSVAVADAHPLLRPRADYVTRIAG
GRGAVREVCDLLLLAQGKLEDAKGQSL

Sequences:

>Translated_187_residues
MQETPTVETCYGPVAQQVLESARTIRLLICDVDGVMSDGLIYMGNHGEELKTFNVRDGYGIRCLLTSGIEVAIITGRSAR
LLEDRCTTLGITHIYQGQSDKTLAFRALLSKLKLTAEQVAYVGDDLIDAPVMDQVGLSVAVADAHPLLRPRADYVTRIAG
GRGAVREVCDLLLLAQGKLEDAKGQSL
>Mature_187_residues
MQETPTVETCYGPVAQQVLESARTIRLLICDVDGVMSDGLIYMGNHGEELKTFNVRDGYGIRCLLTSGIEVAIITGRSAR
LLEDRCTTLGITHIYQGQSDKTLAFRALLSKLKLTAEQVAYVGDDLIDAPVMDQVGLSVAVADAHPLLRPRADYVTRIAG
GRGAVREVCDLLLLAQGKLEDAKGQSL

Specific function: Catalyzes the hydrolysis of KDO 8-P to KDO and inorganic phosphate [H]

COG id: COG1778

COG function: function code R; Low specificity phosphatase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsC family [H]

Homologues:

Organism=Homo sapiens, GI8923900, Length=179, Percent_Identity=30.1675977653631, Blast_Score=88, Evalue=5e-18,
Organism=Escherichia coli, GI2367202, Length=182, Percent_Identity=78.021978021978, Blast_Score=293, Evalue=4e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006549
- InterPro:   IPR010023 [H]

Pfam domain/function: PF08282 Hydrolase_3 [H]

EC number: =3.1.3.45 [H]

Molecular weight: Translated: 20219; Mature: 20219

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQETPTVETCYGPVAQQVLESARTIRLLICDVDGVMSDGLIYMGNHGEELKTFNVRDGYG
CCCCCCHHHHHHHHHHHHHHHCCEEEEEEECCCCHHHCCEEEECCCCCCEEEEECCCCCC
IRCLLTSGIEVAIITGRSARLLEDRCTTLGITHIYQGQSDKTLAFRALLSKLKLTAEQVA
EEEEEECCCEEEEEECCCHHHHHHHHHHCCHHHEECCCCCCHHHHHHHHHHHHHHHHHHH
YVGDDLIDAPVMDQVGLSVAVADAHPLLRPRADYVTRIAGGRGAVREVCDLLLLAQGKLE
HHCCCCCCCCCHHHCCCEEEEECCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHCCCCC
DAKGQSL
CCCCCCC
>Mature Secondary Structure
MQETPTVETCYGPVAQQVLESARTIRLLICDVDGVMSDGLIYMGNHGEELKTFNVRDGYG
CCCCCCHHHHHHHHHHHHHHHCCEEEEEEECCCCHHHCCEEEECCCCCCEEEEECCCCCC
IRCLLTSGIEVAIITGRSARLLEDRCTTLGITHIYQGQSDKTLAFRALLSKLKLTAEQVA
EEEEEECCCEEEEEECCCHHHHHHHHHHCCHHHEECCCCCCHHHHHHHHHHHHHHHHHHH
YVGDDLIDAPVMDQVGLSVAVADAHPLLRPRADYVTRIAGGRGAVREVCDLLLLAQGKLE
HHCCCCCCCCCHHHCCCEEEEECCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHCCCCC
DAKGQSL
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]