Click here to switch to the map view.

The map label for this gene is engD [H]

Identifier: 84625059

GI number: 84625059

Start: 3863048

End: 3864139

Strand: Reverse

Name: engD [H]

Synonym: XOO_3402

Alternate gene names: 84625059

Gene position: 3864139-3863048 (Counterclockwise)

Preceding gene: 84625060

Following gene: 84625058

Centisome position: 78.22

GC content: 62.09

Gene sequence:

>1092_bases
ATGGGTATCAAATGCGGCATCGTCGGCCTGCCCAACGTCGGCAAGTCGACCCTATTCAATGCGCTGACCAAGGCTGGCAT
CGCTGCGGCCAACTTCCCGTTCTGCACCATCGAGCCGAACGTCGGCATCGTGCCGGTGCCCGATCCGCGCCTGAATCAGC
TGGCCGGCATCGTCAAGCCGCAAAAGCTGATTCCCACCGCGGTCGAGTTCGTCGATATCGCCGGCCTGGTTGCTGGCGCG
GCAAGCGGCGAAGGCCTGGGCAATAAGTTCCTGGCGCACATCCGCGAGGTCGATGCGATCACCCACGTGGTGCGTTGCTT
CGACAACGACGACGTGATTCACGTCAATAACAAGGTCGACCCGATCGCCGATATCGAAACCATTGATACCGAGCTGGCGC
TGGCCGATCTGGATAGCGTGGAAAAGGCCCTCAACCGTGCCGAACGCAGTGCAAAAGGCGGCGACAAGGATGCAGCGGCG
CGAAAGCCGGTGCTGGCCAAGTTGCAAGCCGCGCTGGCCGACGGCAAGTCGGGTCGCGCCGCCGGTCTGGACGACGAAGA
AAAGGCGCTGGTGCGTGATCTGTTCCTGCTGACGCTCAAGCCTGTGCTTTACATCGCCAACGTGCTCGAGGACGGTTTCG
AAAACAACCCGCACCTGGATGCGGTACGCGCGCATGCGCTGGCCGAAGGTGCGGAAGTGGTGCCGGTGTCGGCCGCCATC
GAAGAGGAGTTGTCCCAGCTCGACGACGAAGACCGCGACACATTCCTGGCCGATCTCGGCCTGGAAGAGCCAGGGTTGAA
TCGCGTCATTCGTGCGGCTTACACACTGTTGGGTCTGCAGACCTACTTCACTGCGGGCGTCAAGGAAGTGCGTGCCTGGA
CGGTTCGGGCCGGTTCGACGGCACCACAGGCCGCTGCCGTGATCCACACCGATTTCGAGAAGGGCTTCATCCGGGCCGAG
ACGATTGGCTTTGACGACTTCATCAAATACCGCGGCGAAGCCGGTGCCCGCGATGCCGGGCGTCTGCGTCTGGAAGGCAA
GGAATACCGCGTGCAGGAAGGCGATGTGCTGCACTTCCGTTTCAACGTCTGA

Upstream 100 bases:

>100_bases
GTCTGCACACCAGCAGGGATGCGTGATTGGGGATTGGGGATTCGCGGCTGTGCAGCGCTACGAATCTCCAATCCCGAATC
CCAAATCCCGGATGTGACCC

Downstream 100 bases:

>100_bases
TCGGCTGCGCGTGGCTCGTAGAGGCGCGTGTCGGCGATGGTGAAGATTGTTCCAAATTTTTGTTGACACTGCATCCGTCG
CACAGCAAAATAACGGGCTG

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MGIKCGIVGLPNVGKSTLFNALTKAGIAAANFPFCTIEPNVGIVPVPDPRLNQLAGIVKPQKLIPTAVEFVDIAGLVAGA
ASGEGLGNKFLAHIREVDAITHVVRCFDNDDVIHVNNKVDPIADIETIDTELALADLDSVEKALNRAERSAKGGDKDAAA
RKPVLAKLQAALADGKSGRAAGLDDEEKALVRDLFLLTLKPVLYIANVLEDGFENNPHLDAVRAHALAEGAEVVPVSAAI
EEELSQLDDEDRDTFLADLGLEEPGLNRVIRAAYTLLGLQTYFTAGVKEVRAWTVRAGSTAPQAAAVIHTDFEKGFIRAE
TIGFDDFIKYRGEAGARDAGRLRLEGKEYRVQEGDVLHFRFNV

Sequences:

>Translated_363_residues
MGIKCGIVGLPNVGKSTLFNALTKAGIAAANFPFCTIEPNVGIVPVPDPRLNQLAGIVKPQKLIPTAVEFVDIAGLVAGA
ASGEGLGNKFLAHIREVDAITHVVRCFDNDDVIHVNNKVDPIADIETIDTELALADLDSVEKALNRAERSAKGGDKDAAA
RKPVLAKLQAALADGKSGRAAGLDDEEKALVRDLFLLTLKPVLYIANVLEDGFENNPHLDAVRAHALAEGAEVVPVSAAI
EEELSQLDDEDRDTFLADLGLEEPGLNRVIRAAYTLLGLQTYFTAGVKEVRAWTVRAGSTAPQAAAVIHTDFEKGFIRAE
TIGFDDFIKYRGEAGARDAGRLRLEGKEYRVQEGDVLHFRFNV
>Mature_362_residues
GIKCGIVGLPNVGKSTLFNALTKAGIAAANFPFCTIEPNVGIVPVPDPRLNQLAGIVKPQKLIPTAVEFVDIAGLVAGAA
SGEGLGNKFLAHIREVDAITHVVRCFDNDDVIHVNNKVDPIADIETIDTELALADLDSVEKALNRAERSAKGGDKDAAAR
KPVLAKLQAALADGKSGRAAGLDDEEKALVRDLFLLTLKPVLYIANVLEDGFENNPHLDAVRAHALAEGAEVVPVSAAIE
EELSQLDDEDRDTFLADLGLEEPGLNRVIRAAYTLLGLQTYFTAGVKEVRAWTVRAGSTAPQAAAVIHTDFEKGFIRAET
IGFDDFIKYRGEAGARDAGRLRLEGKEYRVQEGDVLHFRFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=369, Percent_Identity=42.5474254742547, Blast_Score=298, Evalue=4e-81,
Organism=Homo sapiens, GI58761502, Length=233, Percent_Identity=34.7639484978541, Blast_Score=145, Evalue=4e-35,
Organism=Escherichia coli, GI1787454, Length=363, Percent_Identity=68.5950413223141, Blast_Score=518, Evalue=1e-148,
Organism=Escherichia coli, GI1789574, Length=128, Percent_Identity=32.03125, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17509631, Length=365, Percent_Identity=40.2739726027397, Blast_Score=283, Evalue=8e-77,
Organism=Saccharomyces cerevisiae, GI6319499, Length=369, Percent_Identity=39.2953929539295, Blast_Score=265, Evalue=1e-71,
Organism=Saccharomyces cerevisiae, GI6321773, Length=381, Percent_Identity=34.1207349081365, Blast_Score=191, Evalue=2e-49,
Organism=Saccharomyces cerevisiae, GI6321649, Length=348, Percent_Identity=30.7471264367816, Blast_Score=96, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24640873, Length=369, Percent_Identity=43.0894308943089, Blast_Score=289, Evalue=2e-78,
Organism=Drosophila melanogaster, GI24640877, Length=369, Percent_Identity=43.0894308943089, Blast_Score=289, Evalue=2e-78,
Organism=Drosophila melanogaster, GI24640875, Length=369, Percent_Identity=43.0894308943089, Blast_Score=289, Evalue=2e-78,
Organism=Drosophila melanogaster, GI24640879, Length=328, Percent_Identity=40.8536585365854, Blast_Score=233, Evalue=2e-61,
Organism=Drosophila melanogaster, GI24585318, Length=171, Percent_Identity=29.2397660818713, Blast_Score=72, Evalue=9e-13,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 38937; Mature: 38805

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIKCGIVGLPNVGKSTLFNALTKAGIAAANFPFCTIEPNVGIVPVPDPRLNQLAGIVKP
CCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCEEECCCCHHHHHHHHCCC
QKLIPTAVEFVDIAGLVAGAASGEGLGNKFLAHIREVDAITHVVRCFDNDDVIHVNNKVD
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCC
PIADIETIDTELALADLDSVEKALNRAERSAKGGDKDAAARKPVLAKLQAALADGKSGRA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHCCCCCCC
AGLDDEEKALVRDLFLLTLKPVLYIANVLEDGFENNPHLDAVRAHALAEGAEVVPVSAAI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEHHHHH
EEELSQLDDEDRDTFLADLGLEEPGLNRVIRAAYTLLGLQTYFTAGVKEVRAWTVRAGST
HHHHHHCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCC
APQAAAVIHTDFEKGFIRAETIGFDDFIKYRGEAGARDAGRLRLEGKEYRVQEGDVLHFR
CCCCEEEEEECHHHCCEEEECCCHHHHHHHCCCCCCCCCCEEEECCCCEEECCCCEEEEE
FNV
ECC
>Mature Secondary Structure 
GIKCGIVGLPNVGKSTLFNALTKAGIAAANFPFCTIEPNVGIVPVPDPRLNQLAGIVKP
CEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCEEECCCCHHHHHHHHCCC
QKLIPTAVEFVDIAGLVAGAASGEGLGNKFLAHIREVDAITHVVRCFDNDDVIHVNNKVD
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCC
PIADIETIDTELALADLDSVEKALNRAERSAKGGDKDAAARKPVLAKLQAALADGKSGRA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHCCCCCCC
AGLDDEEKALVRDLFLLTLKPVLYIANVLEDGFENNPHLDAVRAHALAEGAEVVPVSAAI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEHHHHH
EEELSQLDDEDRDTFLADLGLEEPGLNRVIRAAYTLLGLQTYFTAGVKEVRAWTVRAGST
HHHHHHCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCC
APQAAAVIHTDFEKGFIRAETIGFDDFIKYRGEAGARDAGRLRLEGKEYRVQEGDVLHFR
CCCCEEEEEECHHHCCEEEECCCHHHHHHHCCCCCCCCCCEEEECCCCEEECCCCEEEEE
FNV
ECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]