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The map label for this gene is yuxL [H]

Identifier: 84624888

GI number: 84624888

Start: 3668881

End: 3671073

Strand: Reverse

Name: yuxL [H]

Synonym: XOO_3231

Alternate gene names: 84624888

Gene position: 3671073-3668881 (Counterclockwise)

Preceding gene: 84624889

Following gene: 84624886

Centisome position: 74.31

GC content: 63.84

Gene sequence:

>2193_bases
ATGACCTCCTGCCTTTGCGCGTGCGCCGCAGCAACGCCTACCATCGACGTTTTGCCGTTGCCGGAGATCTCGATGAAGCT
GCGTCACGCCGTATTGCCCTTGTGTTTGCTGGCTGCCCTGCCAAGCCTTGCCGCCGCGCGCGGCTTCGATGTGCGCGACA
TGGTGGCGCTGGACCGAGTGTCTTCGCCCACGCTCAGCCCGGATGGCAGCGTGGTGCTGTTCGCCAAGCGCCAGGCCAAG
ACCGCCAATGGCACGTCGGCCACCAGCCTATGGGTGCGTAACCTGCGTACCCGCGACGTGTCGCCGCCCAAGCGGCTCAC
GCCGGAAGGCTGGAACGTCAACAGCCCGGCGTTTTCGCCGGATGGCAAGACGGTGTACTTCCTCAGCAGCAAAACCGGCA
GCCAGCAGCTCTACGCGCAGCCGATGGCCGGCGGCACCCCGCAGCAACTCACCGCGTTTGCGGTGGATGTGGACAACTAC
AAGCTCTCGCCCGACGGCAAGCGCATCGTTTTCAGCGCAGGCGTGTTCCAGGACTGCGGCTCGGACCTGGGCTGCACCAA
GAAGAAGCTAGGCGAGCTCAAGAACCACAAGGCCAGCGGCGTGGTGTACGACCAGTTGTTCGTACGCCATTGGGACACCT
GGAACGATGGCCGTCGCAATACCTTGTTCGTGGCCGAGCTGCCCGCAGCGGGTGCAAAAGCGGTGGTCGGGGCGTCGGCG
ATCAGCGCCACGCTGGCCGGCGATGCGCCGTCCAAGCCGTTCGGTGGCAACGACGATTACACCTGGTCGCCGGATGGCGC
CAGCGTGGTGGCCAGCGTCCGCATTCCGCAGTCGTATGGCACGGAAGCGGGCAAGAACACCAAGGCCGGCGGCAAGCCGA
CCGGCAATGACGAGCCGTGGCAGACCAACTTCGACCTGTATCGCCTGGATGCAAGCGGCAAGTCTGCGCCGGTCAATCTG
ACTGCGTCCAACCCGGCCTGGGATGCCGGCCCGGTGTTCAGCACCGACGGCAAGACCTTGTACTACCGCGCCATGAAGCG
CCCTGGCTTCGAGGCCGACCGCTTCGGCCTGATGGCGATGGATGTGGCCAGTGGCAAGACGCGCGAGATTGCGCCGACGT
GGGACCGCTCGGCTGGCGAAATCGTATTGAGCGAGGACGGCAGCAGCCTGTACACCAGCGCCGACGATCTCGGTGAGCAT
CCGCTGTTCAAGATCGCTATCGCCAGCGGCGAGGCGACCAGGCTGGTGGGCGAGGGCAGCGTGCACGCCCCCACGCTGGC
CGGCAACACGCTCGCGTTTACCCGTAGCTCGCTCAAGAGTGGCGACCAGGTCTTCGTCAGCGACACGCAAGGCCAGGGGC
TGCGCGCGATCAGCCAGAGCGCCGCTGAACTACTACCGGATGTGCAGTTCGGCGACTACGAGCAGTTCCAGTTCAAGGGC
TGGAACAACGACACCGTGCATGGCTACGTGGTCAAGCCCTACAACTATCAGGAAGGCAAGACCTATCCGGTGGCGTTCCT
GATCCACGGCGGCCCGCAGGGCAGCTTCGGCAATGCCTGGAGCAACCGTTGGAATCCGCAGACCTACGCCGGCCAGGGCT
ACGCGGTGGTGATGATCGACTTCCACGGCTCCACCGGCTACGGCCAGGAATTCACCGACGCCATCAGCCAGCATTGGGGC
GACCGCCCGCTGGAAGATCTGCAAAAAGGCTGGGCCGCCGCACAGAAGCAATACGGCTTCCTCAACGGCGACAAGGCCTG
TGCATTGGGCGCCAGTTACGGCGGCTACATGGTCTATTGGATGGCAGGCAATTGGACTCAACCGTGGAAGTGCCTGGTCG
ACCACGACGGCGTGTTCGACAACCGCACCATGGGCTACGCCACCGAGGAATTGTGGTTCAGCGAATGGGAAAACGGCGGC
ACGCCATGGCAGAACCCGGCCGGCTACGAGAAGTTCAACCCGGTGCTGCATGTCGACAAGTGGAAGGTGCCGATGCTGGT
CATCCACGGCCAGCAGGATTTCCGCATCCCGCTCGAACAAGGCCTGGCCGCATTCACCGCGCTGCAACGCAAGGGCATCG
ATTCCAAGTTCCTGTATTTCCCGGACGAGAACCACTGGGTGCTCAAGCCCGATAACAGCATCTTGTGGCACGACACCGTC
AATGGCTGGCTGAAGCAGCATATCGGCCAGTGA

Upstream 100 bases:

>100_bases
CGTCCACCCCTGTGGGTCGCCGCTCTAAAGCTCTCAGCCGCCCATGCCGCAGGCAGCGGCATGGGCGCGCTCGACGGCGT
GTCGCGTGACCTCGCGCTGT

Downstream 100 bases:

>100_bases
CGGACAACCGGCACGCCGCCAGGCGCGGCGTGTCGGTCGTGCAAGGTAAATAGTCGCCCCTGGAAAACCCCTCTCAAACC
TCCATTACCATGTTTGCGGG

Product: alanyl dipeptidyl peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 730; Mature: 729

Protein sequence:

>730_residues
MTSCLCACAAATPTIDVLPLPEISMKLRHAVLPLCLLAALPSLAAARGFDVRDMVALDRVSSPTLSPDGSVVLFAKRQAK
TANGTSATSLWVRNLRTRDVSPPKRLTPEGWNVNSPAFSPDGKTVYFLSSKTGSQQLYAQPMAGGTPQQLTAFAVDVDNY
KLSPDGKRIVFSAGVFQDCGSDLGCTKKKLGELKNHKASGVVYDQLFVRHWDTWNDGRRNTLFVAELPAAGAKAVVGASA
ISATLAGDAPSKPFGGNDDYTWSPDGASVVASVRIPQSYGTEAGKNTKAGGKPTGNDEPWQTNFDLYRLDASGKSAPVNL
TASNPAWDAGPVFSTDGKTLYYRAMKRPGFEADRFGLMAMDVASGKTREIAPTWDRSAGEIVLSEDGSSLYTSADDLGEH
PLFKIAIASGEATRLVGEGSVHAPTLAGNTLAFTRSSLKSGDQVFVSDTQGQGLRAISQSAAELLPDVQFGDYEQFQFKG
WNNDTVHGYVVKPYNYQEGKTYPVAFLIHGGPQGSFGNAWSNRWNPQTYAGQGYAVVMIDFHGSTGYGQEFTDAISQHWG
DRPLEDLQKGWAAAQKQYGFLNGDKACALGASYGGYMVYWMAGNWTQPWKCLVDHDGVFDNRTMGYATEELWFSEWENGG
TPWQNPAGYEKFNPVLHVDKWKVPMLVIHGQQDFRIPLEQGLAAFTALQRKGIDSKFLYFPDENHWVLKPDNSILWHDTV
NGWLKQHIGQ

Sequences:

>Translated_730_residues
MTSCLCACAAATPTIDVLPLPEISMKLRHAVLPLCLLAALPSLAAARGFDVRDMVALDRVSSPTLSPDGSVVLFAKRQAK
TANGTSATSLWVRNLRTRDVSPPKRLTPEGWNVNSPAFSPDGKTVYFLSSKTGSQQLYAQPMAGGTPQQLTAFAVDVDNY
KLSPDGKRIVFSAGVFQDCGSDLGCTKKKLGELKNHKASGVVYDQLFVRHWDTWNDGRRNTLFVAELPAAGAKAVVGASA
ISATLAGDAPSKPFGGNDDYTWSPDGASVVASVRIPQSYGTEAGKNTKAGGKPTGNDEPWQTNFDLYRLDASGKSAPVNL
TASNPAWDAGPVFSTDGKTLYYRAMKRPGFEADRFGLMAMDVASGKTREIAPTWDRSAGEIVLSEDGSSLYTSADDLGEH
PLFKIAIASGEATRLVGEGSVHAPTLAGNTLAFTRSSLKSGDQVFVSDTQGQGLRAISQSAAELLPDVQFGDYEQFQFKG
WNNDTVHGYVVKPYNYQEGKTYPVAFLIHGGPQGSFGNAWSNRWNPQTYAGQGYAVVMIDFHGSTGYGQEFTDAISQHWG
DRPLEDLQKGWAAAQKQYGFLNGDKACALGASYGGYMVYWMAGNWTQPWKCLVDHDGVFDNRTMGYATEELWFSEWENGG
TPWQNPAGYEKFNPVLHVDKWKVPMLVIHGQQDFRIPLEQGLAAFTALQRKGIDSKFLYFPDENHWVLKPDNSILWHDTV
NGWLKQHIGQ
>Mature_729_residues
TSCLCACAAATPTIDVLPLPEISMKLRHAVLPLCLLAALPSLAAARGFDVRDMVALDRVSSPTLSPDGSVVLFAKRQAKT
ANGTSATSLWVRNLRTRDVSPPKRLTPEGWNVNSPAFSPDGKTVYFLSSKTGSQQLYAQPMAGGTPQQLTAFAVDVDNYK
LSPDGKRIVFSAGVFQDCGSDLGCTKKKLGELKNHKASGVVYDQLFVRHWDTWNDGRRNTLFVAELPAAGAKAVVGASAI
SATLAGDAPSKPFGGNDDYTWSPDGASVVASVRIPQSYGTEAGKNTKAGGKPTGNDEPWQTNFDLYRLDASGKSAPVNLT
ASNPAWDAGPVFSTDGKTLYYRAMKRPGFEADRFGLMAMDVASGKTREIAPTWDRSAGEIVLSEDGSSLYTSADDLGEHP
LFKIAIASGEATRLVGEGSVHAPTLAGNTLAFTRSSLKSGDQVFVSDTQGQGLRAISQSAAELLPDVQFGDYEQFQFKGW
NNDTVHGYVVKPYNYQEGKTYPVAFLIHGGPQGSFGNAWSNRWNPQTYAGQGYAVVMIDFHGSTGYGQEFTDAISQHWGD
RPLEDLQKGWAAAQKQYGFLNGDKACALGASYGGYMVYWMAGNWTQPWKCLVDHDGVFDNRTMGYATEELWFSEWENGGT
PWQNPAGYEKFNPVLHVDKWKVPMLVIHGQQDFRIPLEQGLAAFTALQRKGIDSKFLYFPDENHWVLKPDNSILWHDTVN
GWLKQHIGQ

Specific function: Involved In The Tonb-Independent Uptake Of Group A Colicins (Colicins A, E1, E2, E3 And K). Necessary For The Colicins To Reach Their Respective Targets After Initial Binding To The Bacteria. [C]

COG id: COG1506

COG function: function code E; Dipeptidyl aminopeptidases/acylaminoacyl-peptidases

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9B family [H]

Homologues:

Organism=Homo sapiens, GI23510451, Length=296, Percent_Identity=22.6351351351351, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI194394146, Length=383, Percent_Identity=26.8929503916449, Blast_Score=100, Evalue=8e-21,
Organism=Homo sapiens, GI37577089, Length=358, Percent_Identity=25.1396648044693, Blast_Score=90, Evalue=9e-18,
Organism=Homo sapiens, GI18450280, Length=358, Percent_Identity=25.1396648044693, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI18765694, Length=272, Percent_Identity=24.6323529411765, Blast_Score=67, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI25144537, Length=232, Percent_Identity=28.0172413793103, Blast_Score=96, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI25144540, Length=232, Percent_Identity=28.0172413793103, Blast_Score=95, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI25149159, Length=229, Percent_Identity=27.9475982532751, Blast_Score=94, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17552908, Length=205, Percent_Identity=28.2926829268293, Blast_Score=92, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17508017, Length=260, Percent_Identity=24.6153846153846, Blast_Score=80, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17508019, Length=260, Percent_Identity=24.6153846153846, Blast_Score=80, Evalue=5e-15,
Organism=Drosophila melanogaster, GI45551969, Length=237, Percent_Identity=26.1603375527426, Blast_Score=77, Evalue=6e-14,
Organism=Drosophila melanogaster, GI45550825, Length=237, Percent_Identity=26.1603375527426, Blast_Score=76, Evalue=1e-13,
Organism=Drosophila melanogaster, GI45553511, Length=237, Percent_Identity=26.1603375527426, Blast_Score=76, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011042
- InterPro:   IPR011659
- InterPro:   IPR001375 [H]

Pfam domain/function: PF07676 PD40; PF00326 Peptidase_S9 [H]

EC number: NA

Molecular weight: Translated: 79487; Mature: 79355

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSCLCACAAATPTIDVLPLPEISMKLRHAVLPLCLLAALPSLAAARGFDVRDMVALDRV
CCHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHC
SSPTLSPDGSVVLFAKRQAKTANGTSATSLWVRNLRTRDVSPPKRLTPEGWNVNSPAFSP
CCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
DGKTVYFLSSKTGSQQLYAQPMAGGTPQQLTAFAVDVDNYKLSPDGKRIVFSAGVFQDCG
CCCEEEEEECCCCCCEEEECCCCCCCHHHEEEEEEEECCEEECCCCCEEEEECCCHHHCC
SDLGCTKKKLGELKNHKASGVVYDQLFVRHWDTWNDGRRNTLFVAELPAAGAKAVVGASA
CCCCCCHHHHHHHHCCCCCCEEHHHHHHHHCCCCCCCCCCEEEEEECCCCCCHHHHHHHH
ISATLAGDAPSKPFGGNDDYTWSPDGASVVASVRIPQSYGTEAGKNTKAGGKPTGNDEPW
HHEEECCCCCCCCCCCCCCCEECCCCCEEEEEEECCHHHCCCCCCCCCCCCCCCCCCCCC
QTNFDLYRLDASGKSAPVNLTASNPAWDAGPVFSTDGKTLYYRAMKRPGFEADRFGLMAM
CCCCEEEEECCCCCCCCEEEEECCCCCCCCCEEECCCCEEEEEECCCCCCCCHHCCEEEE
DVASGKTREIAPTWDRSAGEIVLSEDGSSLYTSADDLGEHPLFKIAIASGEATRLVGEGS
EECCCCCCCCCCCCCCCCCEEEEECCCCEEEECHHHCCCCCEEEEEEECCCEEEEEECCC
VHAPTLAGNTLAFTRSSLKSGDQVFVSDTQGQGLRAISQSAAELLPDVQFGDYEQFQFKG
CCCCEECCCEEEEEHHHHCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEC
WNNDTVHGYVVKPYNYQEGKTYPVAFLIHGGPQGSFGNAWSNRWNPQTYAGQGYAVVMID
CCCCCEEEEEECCEECCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEEE
FHGSTGYGQEFTDAISQHWGDRPLEDLQKGWAAAQKQYGFLNGDKACALGASYGGYMVYW
ECCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCEEEEE
MAGNWTQPWKCLVDHDGVFDNRTMGYATEELWFSEWENGGTPWQNPAGYEKFNPVLHVDK
EECCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHCCCCEEECC
WKVPMLVIHGQQDFRIPLEQGLAAFTALQRKGIDSKFLYFPDENHWVLKPDNSILWHDTV
CCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCEEEECCCCCEEEECHH
NGWLKQHIGQ
HHHHHHHHCC
>Mature Secondary Structure 
TSCLCACAAATPTIDVLPLPEISMKLRHAVLPLCLLAALPSLAAARGFDVRDMVALDRV
CHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHC
SSPTLSPDGSVVLFAKRQAKTANGTSATSLWVRNLRTRDVSPPKRLTPEGWNVNSPAFSP
CCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
DGKTVYFLSSKTGSQQLYAQPMAGGTPQQLTAFAVDVDNYKLSPDGKRIVFSAGVFQDCG
CCCEEEEEECCCCCCEEEECCCCCCCHHHEEEEEEEECCEEECCCCCEEEEECCCHHHCC
SDLGCTKKKLGELKNHKASGVVYDQLFVRHWDTWNDGRRNTLFVAELPAAGAKAVVGASA
CCCCCCHHHHHHHHCCCCCCEEHHHHHHHHCCCCCCCCCCEEEEEECCCCCCHHHHHHHH
ISATLAGDAPSKPFGGNDDYTWSPDGASVVASVRIPQSYGTEAGKNTKAGGKPTGNDEPW
HHEEECCCCCCCCCCCCCCCEECCCCCEEEEEEECCHHHCCCCCCCCCCCCCCCCCCCCC
QTNFDLYRLDASGKSAPVNLTASNPAWDAGPVFSTDGKTLYYRAMKRPGFEADRFGLMAM
CCCCEEEEECCCCCCCCEEEEECCCCCCCCCEEECCCCEEEEEECCCCCCCCHHCCEEEE
DVASGKTREIAPTWDRSAGEIVLSEDGSSLYTSADDLGEHPLFKIAIASGEATRLVGEGS
EECCCCCCCCCCCCCCCCCEEEEECCCCEEEECHHHCCCCCEEEEEEECCCEEEEEECCC
VHAPTLAGNTLAFTRSSLKSGDQVFVSDTQGQGLRAISQSAAELLPDVQFGDYEQFQFKG
CCCCEECCCEEEEEHHHHCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEC
WNNDTVHGYVVKPYNYQEGKTYPVAFLIHGGPQGSFGNAWSNRWNPQTYAGQGYAVVMID
CCCCCEEEEEECCEECCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEEE
FHGSTGYGQEFTDAISQHWGDRPLEDLQKGWAAAQKQYGFLNGDKACALGASYGGYMVYW
ECCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCEEEEE
MAGNWTQPWKCLVDHDGVFDNRTMGYATEELWFSEWENGGTPWQNPAGYEKFNPVLHVDK
EECCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHCCCCEEECC
WKVPMLVIHGQQDFRIPLEQGLAAFTALQRKGIDSKFLYFPDENHWVLKPDNSILWHDTV
CCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCEEEECCCCCEEEECHH
NGWLKQHIGQ
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 3098560 [H]