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The map label for this gene is hypA

Identifier: 84490019

GI number: 84490019

Start: 1401727

End: 1402110

Strand: Direct

Name: hypA

Synonym: Msp_1230

Alternate gene names: 84490019

Gene position: 1401727-1402110 (Clockwise)

Preceding gene: 84490017

Following gene: 84490020

Centisome position: 79.31

GC content: 31.77

Gene sequence:

>384_bases
ATGCATGAATTATCCATGGCAAATAGTATGGTTGAAGCTATACTTGATACTGCAAAGAAAAATAATGCTATTAAAATAAC
TGAAGCCATTTTAGAAGTTGGAGAACTCACTATGCTTAATCCTGAACAGTTACGTTTTATGATGGATATTTTAAGAGAAG
ATACTATCTTCGAGGATGCTGAAATCATAATTAACATGATACCTATTGAAGTAGAATGTGAAGATTGTGGTTTTCATGGA
ATTAGTAAAACTGATGAAGGTATGGATCATTTAATGGCTGTAGCCACCTGTCCTGAATGTGACAACACTCATGTTCATAT
TCTAAAAGGACAAGAATGTAATATTAAAACTATAAAAATTGAGAGGGAAGATGAAAATGCATAA

Upstream 100 bases:

>100_bases
TAATACTATTTAGCACATATATAATAATTACAAAGAAAAATAAAATAAAAATAAATTAATTAATTTATATTGAAAAATAC
AATAGTGGAGTTAAAAAAAA

Downstream 100 bases:

>100_bases
TATTGCTAGTATAGAAGTTGAACAAGACATAATCCAAGCTAATGATAAATTAGCTTCTGAAAATAGAAAAAAATTTGAAG
AAAAAGATATTTTTGCTGTT

Product: hydrogenase nickel incorporation protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 127; Mature: 127

Protein sequence:

>127_residues
MHELSMANSMVEAILDTAKKNNAIKITEAILEVGELTMLNPEQLRFMMDILREDTIFEDAEIIINMIPIEVECEDCGFHG
ISKTDEGMDHLMAVATCPECDNTHVHILKGQECNIKTIKIEREDENA

Sequences:

>Translated_127_residues
MHELSMANSMVEAILDTAKKNNAIKITEAILEVGELTMLNPEQLRFMMDILREDTIFEDAEIIINMIPIEVECEDCGFHG
ISKTDEGMDHLMAVATCPECDNTHVHILKGQECNIKTIKIEREDENA
>Mature_127_residues
MHELSMANSMVEAILDTAKKNNAIKITEAILEVGELTMLNPEQLRFMMDILREDTIFEDAEIIINMIPIEVECEDCGFHG
ISKTDEGMDHLMAVATCPECDNTHVHILKGQECNIKTIKIEREDENA

Specific function: Probably plays a role in an hydrogenase nickel cofactor insertion step

COG id: COG0375

COG function: function code R; Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypA/hybF family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HYPA_METST (Q2NEZ5)

Other databases:

- EMBL:   CP000102
- RefSeq:   YP_448251.1
- STRING:   Q2NEZ5
- GeneID:   3855474
- GenomeReviews:   CP000102_GR
- KEGG:   mst:Msp_1230
- NMPDR:   fig|339860.6.peg.1179
- eggNOG:   arNOG11688
- HOGENOM:   HBG688671
- OMA:   MHELSYA
- PhylomeDB:   Q2NEZ5
- ProtClustDB:   PRK00762
- BioCyc:   MSTA339860:MSP_1230-MONOMER
- HAMAP:   MF_00213
- InterPro:   IPR000688
- InterPro:   IPR020538
- TIGRFAMs:   TIGR00100

Pfam domain/function: PF01155 HypA

EC number: NA

Molecular weight: Translated: 14348; Mature: 14348

Theoretical pI: Translated: 4.14; Mature: 4.14

Prosite motif: PS01249 HYPA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.9 %Cys     (Translated Protein)
7.1 %Met     (Translated Protein)
11.0 %Cys+Met (Translated Protein)
3.9 %Cys     (Mature Protein)
7.1 %Met     (Mature Protein)
11.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHELSMANSMVEAILDTAKKNNAIKITEAILEVGELTMLNPEQLRFMMDILREDTIFEDA
CCCHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHCCEECCCHHHHHHHHHHHHCCCCCCCC
EIIINMIPIEVECEDCGFHGISKTDEGMDHLMAVATCPECDNTHVHILKGQECNIKTIKI
EEEEEECCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEEEE
EREDENA
ECCCCCC
>Mature Secondary Structure
MHELSMANSMVEAILDTAKKNNAIKITEAILEVGELTMLNPEQLRFMMDILREDTIFEDA
CCCHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHCCEECCCHHHHHHHHHHHHCCCCCCCC
EIIINMIPIEVECEDCGFHGISKTDEGMDHLMAVATCPECDNTHVHILKGQECNIKTIKI
EEEEEECCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEEEE
EREDENA
ECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA