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The map label for this gene is hypB

Identifier: 84490020

GI number: 84490020

Start: 1402103

End: 1402759

Strand: Direct

Name: hypB

Synonym: Msp_1231

Alternate gene names: 84490020

Gene position: 1402103-1402759 (Clockwise)

Preceding gene: 84490019

Following gene: 84490021

Centisome position: 79.33

GC content: 30.9

Gene sequence:

>657_bases
ATGCATAATATTGCTAGTATAGAAGTTGAACAAGACATAATCCAAGCTAATGATAAATTAGCTTCTGAAAATAGAAAAAA
ATTTGAAGAAAAAGATATTTTTGCTGTTGATTTAGTTGGAGCTGTAGGTTCTGGTAAAACATCACTTCTTGAAACTTTAA
TTGATGAAATGGATGATAAAATCGGTGTTATTGCAGGAGATATACTAAGTAAATTCGATGCAAAAAGAATTGAAAATAAA
AATGTACCTGTAAAAGGACTTAATACTGGAAAAGAATGTCATCTTGATGCTCATCTTGTTGAACATGCACTACCTGATAT
CCCATTAGATGACATTTCCATATTATTCATAGAAAATGTAGGAAACCTAATTTGTCCAGCTGACTTTAATCTTGGAGCAC
ATGTTAGAACAGTTATTATCAGTGTAACTGAAGGTGATGATACTGCTGAGAAACATCCAATGATTTTTAAAGGAGCAGAC
ATGGCTATTATCAACAAAGTAGATTTAGCTGAAGCTGTAGGTGCAGATGCTGATAAAATGGTTGAAGATGTTAAAACAAT
AAATCCTGATATACCTGTTGTTAAATGTAGTTTAAAAACTGGTGAAGGTGTAGATGAAATTATTAGTCTATACAAGAAAT
TCCAAAATAAAGAATAA

Upstream 100 bases:

>100_bases
GCTGTAGCCACCTGTCCTGAATGTGACAACACTCATGTTCATATTCTAAAAGGACAAGAATGTAATATTAAAACTATAAA
AATTGAGAGGGAAGATGAAA

Downstream 100 bases:

>100_bases
GTTTTAAAAACTTATTTTATCTACTTTTTTTTTAAAAAAATAATAAATAGGATGCTATTGTTATGAAGATATGGATAGAT
ATTGTAAATACACCCCATGT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 218; Mature: 218

Protein sequence:

>218_residues
MHNIASIEVEQDIIQANDKLASENRKKFEEKDIFAVDLVGAVGSGKTSLLETLIDEMDDKIGVIAGDILSKFDAKRIENK
NVPVKGLNTGKECHLDAHLVEHALPDIPLDDISILFIENVGNLICPADFNLGAHVRTVIISVTEGDDTAEKHPMIFKGAD
MAIINKVDLAEAVGADADKMVEDVKTINPDIPVVKCSLKTGEGVDEIISLYKKFQNKE

Sequences:

>Translated_218_residues
MHNIASIEVEQDIIQANDKLASENRKKFEEKDIFAVDLVGAVGSGKTSLLETLIDEMDDKIGVIAGDILSKFDAKRIENK
NVPVKGLNTGKECHLDAHLVEHALPDIPLDDISILFIENVGNLICPADFNLGAHVRTVIISVTEGDDTAEKHPMIFKGAD
MAIINKVDLAEAVGADADKMVEDVKTINPDIPVVKCSLKTGEGVDEIISLYKKFQNKE
>Mature_218_residues
MHNIASIEVEQDIIQANDKLASENRKKFEEKDIFAVDLVGAVGSGKTSLLETLIDEMDDKIGVIAGDILSKFDAKRIENK
NVPVKGLNTGKECHLDAHLVEHALPDIPLDDISILFIENVGNLICPADFNLGAHVRTVIISVTEGDDTAEKHPMIFKGAD
MAIINKVDLAEAVGADADKMVEDVKTINPDIPVVKCSLKTGEGVDEIISLYKKFQNKE

Specific function: Could be involved in nickel binding and accumulation [H]

COG id: COG0378

COG function: function code OK; Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypB/hupM family [H]

Homologues:

Organism=Escherichia coli, GI1789082, Length=206, Percent_Identity=41.2621359223301, Blast_Score=173, Evalue=7e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR004392
- InterPro:   IPR012202 [H]

Pfam domain/function: PF02492 cobW [H]

EC number: NA

Molecular weight: Translated: 23758; Mature: 23758

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHNIASIEVEQDIIQANDKLASENRKKFEEKDIFAVDLVGAVGSGKTSLLETLIDEMDDK
CCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHCCH
IGVIAGDILSKFDAKRIENKNVPVKGLNTGKECHLDAHLVEHALPDIPLDDISILFIENV
HHHHHHHHHHHHHHHHHCCCCCCEECCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEEECC
GNLICPADFNLGAHVRTVIISVTEGDDTAEKHPMIFKGADMAIINKVDLAEAVGADADKM
CCEECCCCCCCCCEEEEEEEEEECCCCCHHHCCEEEECCCEEEEEHHHHHHHHCCCHHHH
VEDVKTINPDIPVVKCSLKTGEGVDEIISLYKKFQNKE
HHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MHNIASIEVEQDIIQANDKLASENRKKFEEKDIFAVDLVGAVGSGKTSLLETLIDEMDDK
CCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHCCH
IGVIAGDILSKFDAKRIENKNVPVKGLNTGKECHLDAHLVEHALPDIPLDDISILFIENV
HHHHHHHHHHHHHHHHHCCCCCCEECCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEEECC
GNLICPADFNLGAHVRTVIISVTEGDDTAEKHPMIFKGADMAIINKVDLAEAVGADADKM
CCEECCCCCCCCCEEEEEEEEEECCCCCHHHCCEEEECCCEEEEEHHHHHHHHCCCHHHH
VEDVKTINPDIPVVKCSLKTGEGVDEIISLYKKFQNKE
HHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]