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The map label for this gene is 83721076

Identifier: 83721076

GI number: 83721076

Start: 341156

End: 342106

Strand: Direct

Name: 83721076

Synonym: BTH_I0308

Alternate gene names: NA

Gene position: 341156-342106 (Clockwise)

Preceding gene: 83719170

Following gene: 83718485

Centisome position: 8.96

GC content: 67.82

Gene sequence:

>951_bases
ATGACGCGACGATCGCGCTCCTACAATAACGTGACAACAATTCGAGAGAACAAGACCATGTCGTTTGAGGAGTTCGCGCC
GTTTCGCGTGACGGCGCAAGACGTCGACATCTTCGGCGTCAAAGGAGGCGCGGGACCGCCGCTTCTGTTGCTGCACGGGC
ACCCGCAAACGCACATGATCTGGCATCGCGTCGCCGCGACGCTCGCCAGACATTTCACGGTGATCGCCACCGATCTGCGC
GGCTACGGCGCGTCGGGCAAGCCGCCGAGCGATGCGCGGCACGCGCCGTATTCGAAGCGCACGATGGCGGCCGACCAGGT
CGCCGTGATGCGTCACTTCGGCTTTGCGCGCTTCTACGTGTGCGCGCACGACCGCGGCGCGCGCGTCGCGCACCGGATGG
CGCTCGATCATCCGGATGCGGTCGAGCGGATGCTGCTGCTCGACATCGCGCCGACGCTCGCGATGTACGAGCGCACCGAC
CGCGCGTTCGCGACCGCGTACTTCCACTGGTTCTTCCTGATTCAGCCCGAGCCGTTGCCCGAGACGCTGATCGGCGGCCA
TTCGGACGCGTACGTCGACGCGGTGATGGGCAATCGCTCGGCGGGGCTCGCGCCGTTTGCGCCGGAGGCGCTGCACGCGT
ATCGCGAAGCGTTGCGGCAGCCGGGCGCGGTGCATGCGATGTGCGAGGACTATCGCGCGTCGGCGACGATCGATCTCGAT
CACGATCGTGCGGATCTCGAGCGCGGGCACAAGCTCGCGTGTCCGCTGCGCGTGCTGTGGGGCGAGCACGGCGTCGTCGC
GCGCTGCTTCGCGCCGCTCGACGAATGGCGGCGCGTCGCGCGCGACGTGAGCGGCCGGGCGCTCGCATGCGGGCATTACA
TTCCGGAAGAGGCGCCCGTCGCGCTGATCGATGAGATCGTGTCGTTCTTCGAGGCGCGCGAGGCGGCGTGA

Upstream 100 bases:

>100_bases
ACGAACGGTCGTTCCATTATAGACGCGCCTGGACGAACGCGTAGCCGCGCGGCTGTCGAATGAGTGCTCTGTTTCTACGC
TTTGCGCGGGTATGGCGACG

Downstream 100 bases:

>100_bases
GGCCGCCGCCGCGCAGGCGGCGATCGGCGGCATCGCGATGCGCTGCGCTGAGATGCGCTGCGTTTCGCGCCGCCCGCGCG
TCAATCTTCTTCGGGCGCGA

Product: epoxide hydrolase-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MTRRSRSYNNVTTIRENKTMSFEEFAPFRVTAQDVDIFGVKGGAGPPLLLLHGHPQTHMIWHRVAATLARHFTVIATDLR
GYGASGKPPSDARHAPYSKRTMAADQVAVMRHFGFARFYVCAHDRGARVAHRMALDHPDAVERMLLLDIAPTLAMYERTD
RAFATAYFHWFFLIQPEPLPETLIGGHSDAYVDAVMGNRSAGLAPFAPEALHAYREALRQPGAVHAMCEDYRASATIDLD
HDRADLERGHKLACPLRVLWGEHGVVARCFAPLDEWRRVARDVSGRALACGHYIPEEAPVALIDEIVSFFEAREAA

Sequences:

>Translated_316_residues
MTRRSRSYNNVTTIRENKTMSFEEFAPFRVTAQDVDIFGVKGGAGPPLLLLHGHPQTHMIWHRVAATLARHFTVIATDLR
GYGASGKPPSDARHAPYSKRTMAADQVAVMRHFGFARFYVCAHDRGARVAHRMALDHPDAVERMLLLDIAPTLAMYERTD
RAFATAYFHWFFLIQPEPLPETLIGGHSDAYVDAVMGNRSAGLAPFAPEALHAYREALRQPGAVHAMCEDYRASATIDLD
HDRADLERGHKLACPLRVLWGEHGVVARCFAPLDEWRRVARDVSGRALACGHYIPEEAPVALIDEIVSFFEAREAA
>Mature_315_residues
TRRSRSYNNVTTIRENKTMSFEEFAPFRVTAQDVDIFGVKGGAGPPLLLLHGHPQTHMIWHRVAATLARHFTVIATDLRG
YGASGKPPSDARHAPYSKRTMAADQVAVMRHFGFARFYVCAHDRGARVAHRMALDHPDAVERMLLLDIAPTLAMYERTDR
AFATAYFHWFFLIQPEPLPETLIGGHSDAYVDAVMGNRSAGLAPFAPEALHAYREALRQPGAVHAMCEDYRASATIDLDH
DRADLERGHKLACPLRVLWGEHGVVARCFAPLDEWRRVARDVSGRALACGHYIPEEAPVALIDEIVSFFEAREAA

Specific function: Catalyzes the hydrolytic defluorination of fluoroacetate to produce glycolate. Has low activity towards chloroacetate [H]

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Epoxide hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI218777840, Length=279, Percent_Identity=27.5985663082437, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI13376164, Length=279, Percent_Identity=27.5985663082437, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI218777837, Length=232, Percent_Identity=24.5689655172414, Blast_Score=74, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17554012, Length=292, Percent_Identity=21.9178082191781, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17562298, Length=222, Percent_Identity=22.972972972973, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.8.1.3 [H]

Molecular weight: Translated: 35280; Mature: 35148

Theoretical pI: Translated: 7.32; Mature: 7.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRRSRSYNNVTTIRENKTMSFEEFAPFRVTAQDVDIFGVKGGAGPPLLLLHGHPQTHMI
CCCCCCCCCCCEEEECCCCCCHHHCCCEEEEECCCEEEEECCCCCCCEEEEECCCCHHHH
WHRVAATLARHFTVIATDLRGYGASGKPPSDARHAPYSKRTMAADQVAVMRHFGFARFYV
HHHHHHHHHHHHHEEEEHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEE
CAHDRGARVAHRMALDHPDAVERMLLLDIAPTLAMYERTDRAFATAYFHWFFLIQPEPLP
EECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCC
ETLIGGHSDAYVDAVMGNRSAGLAPFAPEALHAYREALRQPGAVHAMCEDYRASATIDLD
HHHHCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHCCCCEEEEEC
HDRADLERGHKLACPLRVLWGEHGVVARCFAPLDEWRRVARDVSGRALACGHYIPEEAPV
CCHHHHHCCCEECCCCEEEECCCCHHHHHHHCHHHHHHHHHCCCCCEEEECCCCCCCCCH
ALIDEIVSFFEAREAA
HHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TRRSRSYNNVTTIRENKTMSFEEFAPFRVTAQDVDIFGVKGGAGPPLLLLHGHPQTHMI
CCCCCCCCCCEEEECCCCCCHHHCCCEEEEECCCEEEEECCCCCCCEEEEECCCCHHHH
WHRVAATLARHFTVIATDLRGYGASGKPPSDARHAPYSKRTMAADQVAVMRHFGFARFYV
HHHHHHHHHHHHHEEEEHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEE
CAHDRGARVAHRMALDHPDAVERMLLLDIAPTLAMYERTDRAFATAYFHWFFLIQPEPLP
EECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCC
ETLIGGHSDAYVDAVMGNRSAGLAPFAPEALHAYREALRQPGAVHAMCEDYRASATIDLD
HHHHCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHCCCCEEEEEC
HDRADLERGHKLACPLRVLWGEHGVVARCFAPLDEWRRVARDVSGRALACGHYIPEEAPV
CCHHHHHCCCEECCCCEEEECCCCHHHHHHHCHHHHHHHHHCCCCCEEEECCCCCCCCCH
ALIDEIVSFFEAREAA
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA