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The map label for this gene is lpxA [H]

Identifier: 83720787

GI number: 83720787

Start: 2311035

End: 2311823

Strand: Direct

Name: lpxA [H]

Synonym: BTH_I2039

Alternate gene names: 83720787

Gene position: 2311035-2311823 (Clockwise)

Preceding gene: 83721525

Following gene: 83719655

Centisome position: 60.67

GC content: 66.79

Gene sequence:

>789_bases
ATGAGCAGGATTCACCCCACGGCGATCATCGAGCCGGGCGCGCAGCTCCACGAGACGGTCGAGGTCGGCCCATACGCGAT
CGTCGGTTCGAACGTGACGATCGGCGCGCGCACGACGATCGGCTCGCACAGCGTGATCGAAGGCCATACGACGATCGGCG
AAGACAATCGCATCGGCCATTACGCGTCGGTGGGCGGCCGTCCGCAGGACATGAAGTACAAGGACGAGCCGACGCGGCTC
GTGATCGGCGATCGCAACACGATCCGCGAATTCACGACGATCCACACGGGCACCGTTCAGGACGCGGGCGTCACGACGCT
CGGCGACGACAACTGGATCATGGCGTACGTGCACATCGGTCACGACTGCCGCGTCGGCAGCCACGTGGTCCTGTCGAGCA
ACGCGCAGATGGCGGGGCACGTCGAGATCGGCGACTGGGCGATCGTCGGCGGGATGTCGGGCGTTCACCAGTACGTGCGA
ATCGGCGCGCATTCGATGCTGGGCGGCGCGTCCGCGCTCGTGCAGGACATTCCGCCGTTCGTGATCGCGGCGGGCAACAA
GGCCGAGCCGCACGGGATCAACGTCGAAGGGCTGCGCCGACGCGGCTTCTCGCCGGACGCAATTTCCGCGCTGCGCAGCG
CGTACCGTATCCTGTACAAGAACAGCCTGTCGCTCGAAGAGGCGAAGGTCCAGCTGAGCGAGCTCGCGCAGGCGGGCGGC
GACGGCGACGCGGCCGTGAAGGCGCTCGTCGACTTCGTCGAGTCGTCGCAGCGCGGCATCATTCGCTGA

Upstream 100 bases:

>100_bases
GCCGAGCTGATGTGCACGGTCAAGACGGCCGACGCGGCGCCCTGAGCGCGCGGCACGCAAGGCTACGCAACGCGACATAG
ACATTGAGAGGCAACGGCGC

Downstream 100 bases:

>100_bases
ACGATGGCGTTCCAACCCACACCGCTGCGCGTCGCGCTCGTCGCGGGCGAACCGTCGGGCGACCTGCTCGGCGCGTCGCT
CCTCGGCGGGCTGCACGCGC

Product: UDP-N-acetylglucosamine acyltransferase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine acyltransferase [H]

Number of amino acids: Translated: 262; Mature: 261

Protein sequence:

>262_residues
MSRIHPTAIIEPGAQLHETVEVGPYAIVGSNVTIGARTTIGSHSVIEGHTTIGEDNRIGHYASVGGRPQDMKYKDEPTRL
VIGDRNTIREFTTIHTGTVQDAGVTTLGDDNWIMAYVHIGHDCRVGSHVVLSSNAQMAGHVEIGDWAIVGGMSGVHQYVR
IGAHSMLGGASALVQDIPPFVIAAGNKAEPHGINVEGLRRRGFSPDAISALRSAYRILYKNSLSLEEAKVQLSELAQAGG
DGDAAVKALVDFVESSQRGIIR

Sequences:

>Translated_262_residues
MSRIHPTAIIEPGAQLHETVEVGPYAIVGSNVTIGARTTIGSHSVIEGHTTIGEDNRIGHYASVGGRPQDMKYKDEPTRL
VIGDRNTIREFTTIHTGTVQDAGVTTLGDDNWIMAYVHIGHDCRVGSHVVLSSNAQMAGHVEIGDWAIVGGMSGVHQYVR
IGAHSMLGGASALVQDIPPFVIAAGNKAEPHGINVEGLRRRGFSPDAISALRSAYRILYKNSLSLEEAKVQLSELAQAGG
DGDAAVKALVDFVESSQRGIIR
>Mature_261_residues
SRIHPTAIIEPGAQLHETVEVGPYAIVGSNVTIGARTTIGSHSVIEGHTTIGEDNRIGHYASVGGRPQDMKYKDEPTRLV
IGDRNTIREFTTIHTGTVQDAGVTTLGDDNWIMAYVHIGHDCRVGSHVVLSSNAQMAGHVEIGDWAIVGGMSGVHQYVRI
GAHSMLGGASALVQDIPPFVIAAGNKAEPHGINVEGLRRRGFSPDAISALRSAYRILYKNSLSLEEAKVQLSELAQAGGD
GDAAVKALVDFVESSQRGIIR

Specific function: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell [H]

COG id: COG1043

COG function: function code M; Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family. LpxA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786378, Length=259, Percent_Identity=52.1235521235521, Blast_Score=286, Evalue=7e-79,
Organism=Escherichia coli, GI1786376, Length=208, Percent_Identity=26.9230769230769, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010137
- InterPro:   IPR011004 [H]

Pfam domain/function: NA

EC number: =2.3.1.129 [H]

Molecular weight: Translated: 27875; Mature: 27744

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRIHPTAIIEPGAQLHETVEVGPYAIVGSNVTIGARTTIGSHSVIEGHTTIGEDNRIGH
CCCCCCCEEECCCHHHHHHHCCCCEEEECCCEEEEEEEECCCCCEEECCCCCCCCCCCCC
YASVGGRPQDMKYKDEPTRLVIGDRNTIREFTTIHTGTVQDAGVTTLGDDNWIMAYVHIG
CCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHEEECCCCCCCCEEEECCCCEEEEEEEEC
HDCRVGSHVVLSSNAQMAGHVEIGDWAIVGGMSGVHQYVRIGAHSMLGGASALVQDIPPF
CCCCCCCEEEEECCCCEEEEEEECCEEEECCHHHHHHHHHHHHHHHHCHHHHHHHHCCCE
VIAAGNKAEPHGINVEGLRRRGFSPDAISALRSAYRILYKNSLSLEEAKVQLSELAQAGG
EEECCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCC
DGDAAVKALVDFVESSQRGIIR
CCHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SRIHPTAIIEPGAQLHETVEVGPYAIVGSNVTIGARTTIGSHSVIEGHTTIGEDNRIGH
CCCCCCEEECCCHHHHHHHCCCCEEEECCCEEEEEEEECCCCCEEECCCCCCCCCCCCC
YASVGGRPQDMKYKDEPTRLVIGDRNTIREFTTIHTGTVQDAGVTTLGDDNWIMAYVHIG
CCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHEEECCCCCCCCEEEECCCCEEEEEEEEC
HDCRVGSHVVLSSNAQMAGHVEIGDWAIVGGMSGVHQYVRIGAHSMLGGASALVQDIPPF
CCCCCCCEEEEECCCCEEEEEEECCEEEECCHHHHHHHHHHHHHHHHCHHHHHHHHCCCE
VIAAGNKAEPHGINVEGLRRRGFSPDAISALRSAYRILYKNSLSLEEAKVQLSELAQAGG
EEECCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCC
DGDAAVKALVDFVESSQRGIIR
CCHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA