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The map label for this gene is fabZ

Identifier: 83721525

GI number: 83721525

Start: 2310497

End: 2310979

Strand: Direct

Name: fabZ

Synonym: BTH_I2038

Alternate gene names: 83721525

Gene position: 2310497-2310979 (Clockwise)

Preceding gene: 83718496

Following gene: 83720787

Centisome position: 60.66

GC content: 60.87

Gene sequence:

>483_bases
GTGAGACGAACCATCATGAGCACTGAAAAAATCAACTTCGACATTCACAAGATCCTCACGCTGCTGCCGCACCGGTATCC
GATTCTGCTCGTCGATCGCGTGCTCGAACTCGAACCGCACAAGTCCATCAAAGCGTTGAAGAACGTGACGGTCAACGAGC
CGTTCTTCACCGGCCACTTCCCGAAGCGGCCGGTGATGCCGGGCGTGCTGATCATCGAAGCGCTCGCGCAGGCGGCCGCG
CTCCTCACGTTCGCCGAGGCGGAGCCGAAGGATCCGGAGAACACGCTGTATTACTTCGTCGGCATCGACAACGCGCGCTT
CAAGCGCGTCGTCGAGCCGGGCGATCAACTGATCCTGAACGTGACGTTCGAGCGCTATATTCGCGGCATCTGGAAGTTCA
AGGCCGTTGCGGAAGTGGACGGCAAGGTCGCGGCGGAAGCCGAGCTGATGTGCACGGTCAAGACGGCCGACGCGGCGCCC
TGA

Upstream 100 bases:

>100_bases
CACTCGCAGGCTGCCCGCCGCGCCGGCCGATCGAACCGCGCGCCGCTTTCCCCAACGCGGCCCGCATCAGCATTTGCAGT
TATCACCGCGCAGCCATTGC

Downstream 100 bases:

>100_bases
GCGCGCGGCACGCAAGGCTACGCAACGCGACATAGACATTGAGAGGCAACGGCGCATGAGCAGGATTCACCCCACGGCGA
TCATCGAGCCGGGCGCGCAG

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: trans-Delta2-enoyl-acyl-ACP; H2O [C]

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase

Number of amino acids: Translated: 160; Mature: 160

Protein sequence:

>160_residues
MRRTIMSTEKINFDIHKILTLLPHRYPILLVDRVLELEPHKSIKALKNVTVNEPFFTGHFPKRPVMPGVLIIEALAQAAA
LLTFAEAEPKDPENTLYYFVGIDNARFKRVVEPGDQLILNVTFERYIRGIWKFKAVAEVDGKVAAEAELMCTVKTADAAP

Sequences:

>Translated_160_residues
MRRTIMSTEKINFDIHKILTLLPHRYPILLVDRVLELEPHKSIKALKNVTVNEPFFTGHFPKRPVMPGVLIIEALAQAAA
LLTFAEAEPKDPENTLYYFVGIDNARFKRVVEPGDQLILNVTFERYIRGIWKFKAVAEVDGKVAAEAELMCTVKTADAAP
>Mature_160_residues
MRRTIMSTEKINFDIHKILTLLPHRYPILLVDRVLELEPHKSIKALKNVTVNEPFFTGHFPKRPVMPGVLIIEALAQAAA
LLTFAEAEPKDPENTLYYFVGIDNARFKRVVEPGDQLILNVTFERYIRGIWKFKAVAEVDGKVAAEAELMCTVKTADAAP

Specific function: Involved in saturated fatty acids biosynthesis

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily

Homologues:

Organism=Escherichia coli, GI1786377, Length=146, Percent_Identity=57.5342465753425, Blast_Score=176, Evalue=5e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABZ_BURTA (Q2SWY7)

Other databases:

- EMBL:   CP000086
- RefSeq:   YP_442562.1
- ProteinModelPortal:   Q2SWY7
- SMR:   Q2SWY7
- STRING:   Q2SWY7
- GeneID:   3848748
- GenomeReviews:   CP000086_GR
- KEGG:   bte:BTH_I2038
- TIGR:   BTH_I2038
- eggNOG:   COG0764
- HOGENOM:   HBG433282
- OMA:   KERRGVA
- ProtClustDB:   PRK00006
- BioCyc:   BTHA271848:BTH_I2038-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00406
- InterPro:   IPR013114
- InterPro:   IPR010084
- TIGRFAMs:   TIGR01750

Pfam domain/function: PF07977 FabA

EC number: 4.2.1.- [C]

Molecular weight: Translated: 18087; Mature: 18087

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: NA

Important sites: ACT_SITE 59-59

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRTIMSTEKINFDIHKILTLLPHRYPILLVDRVLELEPHKSIKALKNVTVNEPFFTGHF
CCCCCCCCHHCCHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHCCCCCCCEEECCC
PKRPVMPGVLIIEALAQAAALLTFAEAEPKDPENTLYYFVGIDNARFKRVVEPGDQLILN
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCHHHHHHCCCCCEEEEE
VTFERYIRGIWKFKAVAEVDGKVAAEAELMCTVKTADAAP
EEHHHHHHHHHHHHHHHHCCCCEECCEEEEEEEECCCCCC
>Mature Secondary Structure
MRRTIMSTEKINFDIHKILTLLPHRYPILLVDRVLELEPHKSIKALKNVTVNEPFFTGHF
CCCCCCCCHHCCHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHCCCCCCCEEECCC
PKRPVMPGVLIIEALAQAAALLTFAEAEPKDPENTLYYFVGIDNARFKRVVEPGDQLILN
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCHHHHHHCCCCCEEEEE
VTFERYIRGIWKFKAVAEVDGKVAAEAELMCTVKTADAAP
EEHHHHHHHHHHHHHHHHCCCCEECCEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: D-3-hydroxy-acyl-ACP [C]

Specific reaction: D-3-hydroxy-acyl-ACP = trans-Delta2-enoyl-acyl-ACP + H2O [C]

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA