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The map label for this gene is mscS [H]

Identifier: 83720378

GI number: 83720378

Start: 1483498

End: 1484424

Strand: Reverse

Name: mscS [H]

Synonym: BTH_I1322

Alternate gene names: 83720378

Gene position: 1484424-1483498 (Counterclockwise)

Preceding gene: 83721140

Following gene: 83721397

Centisome position: 38.97

GC content: 64.83

Gene sequence:

>927_bases
ATGCGGCGAAGGTTGCTCCATCGCCGCGAGTCGGTTATAAAAGGCCCCTTTCGCGTGGCTTCACGGCCGCCTCCGTTCAA
TTCATTTGGAGACCTCAACGTGGATCTCGCCTCCGTGCAAACCTTCATCGTCACTCGCGGCATCGACTTCGGCCTGCAGG
TCATCGCGTCGATCGCGCTCTGGATCATCGGACGCTGGGCAATCCGGGTCGTCACGAACCTGATGGGCAAGATCATCCGC
AGGAGCGGAAAAGTCGACTCCACGCTGTCGCACTATCTGGAATCCGTCGTGAGCGTGCTGCTCACGGTGCTGCTGATCCT
TGCGATCCTGCAGGTGTTCGGTGTGCAGACGACTTCGTTCGCCGCGCTGCTCGCGGGCCTCGGCCTCGCGGTCGGCACCG
CTTGGGGCGGCCTGCTCGCGCACTTCGCGGCCGGCGTGTTCATGCAGGTGCTGCGCCCGTTCAAGGTCGGCGACGTGATC
TCGGCGGGCGGCGTGACGGGCACCGTCAAGGAGCTCGGCCTCTTCGGCACGACGATCATCACGGCCGACAACGTCGTCAC
GCTCGTCGGCAACAACAAGATCTTCTCCGACAACATCGCGAACTACAGCGCGACGCCGACGCGCCGCGTCGATCTGACGG
CGAAGATCGCACACGGCGTCGACGCGGCCGACGCGATCCAGCGGCTGACGGCGGCGCTCGAGCTGATTCCGAACGTCGTC
AAGCATCCTGCGCCCGACGTCGGCGTGCTGTCGTTCACGCCGGAAGGCCCGCTGCTGTTCGTGCGTCCGTCCACGCAGCC
CGCCAACTACTGGCAAGTGTATTGCGACACCAATCGCGCGATTCTCGACACGTTCCGCGAAGCCGGCTATCCGACGCCGG
AAACGCCGATCGCGCATCGAACGGCCGCCGACGTCGCGAAGCACTGA

Upstream 100 bases:

>100_bases
GCGTGGGAAAAGATCCCCGAAAGCACCGCGATCATTGCGCGCCGCGGCGACATCCGGCAGCTTCCCTTCAAGCCGCGTCG
CTCGACATAGCCCGCCGCGC

Downstream 100 bases:

>100_bases
CGCCGCGACGCGGCGATGCCGCGCGGGCGCCGCGCCGCGATGACGCGTGCGCGCCGGCCCGCTCGTTTCATGCGGATGCG
CCCGCCTCGTCCAGGCGGGC

Product: YggB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MRRRLLHRRESVIKGPFRVASRPPPFNSFGDLNVDLASVQTFIVTRGIDFGLQVIASIALWIIGRWAIRVVTNLMGKIIR
RSGKVDSTLSHYLESVVSVLLTVLLILAILQVFGVQTTSFAALLAGLGLAVGTAWGGLLAHFAAGVFMQVLRPFKVGDVI
SAGGVTGTVKELGLFGTTIITADNVVTLVGNNKIFSDNIANYSATPTRRVDLTAKIAHGVDAADAIQRLTAALELIPNVV
KHPAPDVGVLSFTPEGPLLFVRPSTQPANYWQVYCDTNRAILDTFREAGYPTPETPIAHRTAADVAKH

Sequences:

>Translated_308_residues
MRRRLLHRRESVIKGPFRVASRPPPFNSFGDLNVDLASVQTFIVTRGIDFGLQVIASIALWIIGRWAIRVVTNLMGKIIR
RSGKVDSTLSHYLESVVSVLLTVLLILAILQVFGVQTTSFAALLAGLGLAVGTAWGGLLAHFAAGVFMQVLRPFKVGDVI
SAGGVTGTVKELGLFGTTIITADNVVTLVGNNKIFSDNIANYSATPTRRVDLTAKIAHGVDAADAIQRLTAALELIPNVV
KHPAPDVGVLSFTPEGPLLFVRPSTQPANYWQVYCDTNRAILDTFREAGYPTPETPIAHRTAADVAKH
>Mature_308_residues
MRRRLLHRRESVIKGPFRVASRPPPFNSFGDLNVDLASVQTFIVTRGIDFGLQVIASIALWIIGRWAIRVVTNLMGKIIR
RSGKVDSTLSHYLESVVSVLLTVLLILAILQVFGVQTTSFAALLAGLGLAVGTAWGGLLAHFAAGVFMQVLRPFKVGDVI
SAGGVTGTVKELGLFGTTIITADNVVTLVGNNKIFSDNIANYSATPTRRVDLTAKIAHGVDAADAIQRLTAALELIPNVV
KHPAPDVGVLSFTPEGPLLFVRPSTQPANYWQVYCDTNRAILDTFREAGYPTPETPIAHRTAADVAKH

Specific function: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions. The channel is sensitive to voltage [H]

COG id: COG0668

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI1789291, Length=255, Percent_Identity=30.1960784313725, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1786670, Length=200, Percent_Identity=22.5, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787591, Length=163, Percent_Identity=30.0613496932515, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR011066
- InterPro:   IPR006685
- InterPro:   IPR006686
- InterPro:   IPR011014
- InterPro:   IPR008910 [H]

Pfam domain/function: PF00924 MS_channel; PF05552 TM_helix [H]

EC number: NA

Molecular weight: Translated: 33157; Mature: 33157

Theoretical pI: Translated: 10.40; Mature: 10.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRRLLHRRESVIKGPFRVASRPPPFNSFGDLNVDLASVQTFIVTRGIDFGLQVIASIAL
CCHHHHHHHHHHHCCCHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHH
WIIGRWAIRVVTNLMGKIIRRSGKVDSTLSHYLESVVSVLLTVLLILAILQVFGVQTTSF
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
AALLAGLGLAVGTAWGGLLAHFAAGVFMQVLRPFKVGDVISAGGVTGTVKELGLFGTTII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCHHHHHHHHHHHEEE
TADNVVTLVGNNKIFSDNIANYSATPTRRVDLTAKIAHGVDAADAIQRLTAALELIPNVV
ECCCEEEEEECCEEECCCCCCCCCCCCEEEEEHHHHHCCCCHHHHHHHHHHHHHHHHHHH
KHPAPDVGVLSFTPEGPLLFVRPSTQPANYWQVYCDTNRAILDTFREAGYPTPETPIAHR
HCCCCCCCEEEECCCCCEEEEECCCCCCCEEEEEECCCHHHHHHHHHCCCCCCCCCCCHH
TAADVAKH
HHHHHHCC
>Mature Secondary Structure
MRRRLLHRRESVIKGPFRVASRPPPFNSFGDLNVDLASVQTFIVTRGIDFGLQVIASIAL
CCHHHHHHHHHHHCCCHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHH
WIIGRWAIRVVTNLMGKIIRRSGKVDSTLSHYLESVVSVLLTVLLILAILQVFGVQTTSF
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
AALLAGLGLAVGTAWGGLLAHFAAGVFMQVLRPFKVGDVISAGGVTGTVKELGLFGTTII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCHHHHHHHHHHHEEE
TADNVVTLVGNNKIFSDNIANYSATPTRRVDLTAKIAHGVDAADAIQRLTAALELIPNVV
ECCCEEEEEECCEEECCCCCCCCCCCCEEEEEHHHHHCCCCHHHHHHHHHHHHHHHHHHH
KHPAPDVGVLSFTPEGPLLFVRPSTQPANYWQVYCDTNRAILDTFREAGYPTPETPIAHR
HCCCCCCCEEEECCCCCEEEEECCCCCCCEEEEEECCCHHHHHHHHHCCCCCCCCCCCHH
TAADVAKH
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12542086 [H]