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The map label for this gene is ytpA [H]

Identifier: 83718535

GI number: 83718535

Start: 1858743

End: 1859699

Strand: Reverse

Name: ytpA [H]

Synonym: BTH_I1649

Alternate gene names: 83718535

Gene position: 1859699-1858743 (Counterclockwise)

Preceding gene: 83719394

Following gene: 83720387

Centisome position: 48.82

GC content: 72.0

Gene sequence:

>957_bases
ATGATCGAGCCCATCCTTCATCATGACACTCCGGAGACGCCCGTCATGGATGCCGCCGCTTCGACTTCGCCCGGTCTAGC
CGCCGATCCCGGCTCCGCCCCTCGGCGCGGGCGCCTGCGCACCGCCGACGGGCTCGAGCTCGCGTCCTATCGTTGGCCCG
CAGCCGGGCTCTCGCCCGCGGCGCCGCGGGCGACCGTCGCGCTCGTGCACGGGCTCGCCGAGCACGCGGGACGCTACCAG
GCGCTCGCCGAGCGGCTGAATGCGGCGGGCATCGAGGTTGTCGCGATCGATTTGCGCGGGCACGGGCATTCGCCCGGCGA
ACGCGCGTGGGTCGAGCGCTTCGATCAATATCTGGAGGACGCGGACGCGCTCGTCGCAAGCGTCGCGCGCGACGACACGC
CGCTCTTCCTGATGGGACACAGCATGGGCGGCGCGGTCGCCGCGCTCTATGCGGTCGAGCGCGCGGCCGTGCGTCGTCCG
GGCTTGACGGGCCTGATCCTGTCGAGCCCCGCGCTCGCGCCGGGACGCGACGTGCCGAGGTGGATGCTCGCGATGAGCCG
CTTCATCAGCCGCGTGTGGCCCCGCTTTCCGGCGATCAAGATCGACGCCGCGCTGCTGTCGCGCGATCCGGCCGTGGTCG
CCGCGAATCGCGCCGACCCGCTCGTCCATCACGGCCCGGTGCCGGCGCGCACGGGCGCCGAGATTCTCGACGCGATGCGA
CGAATCGAGGCCGGCCGCGCGGCGCTGCGCGTGCCCGTCCTCGTCTATCACGGCACCGCCGACAAGCTGACCGAACCCGA
CGGCAGCCGCGACTTCGGCCGGCATGTCGGCTCGCCCGACCGCACGCTCACGCTGTACGAAGGCAACTATCACGAGACAA
TGAACGATCTGGAACGTGAGCGCGTGATCGGCGCGCAGATCGACTGGATCGCCGCGCGCGCGCCGGCGCGCGGTTGA

Upstream 100 bases:

>100_bases
ACCGCATTCGTCACATTTCCCTTAATAATCGATTTCCACCTTTTCATAACCAAAGGCGATTAGAGGACGACGCCCGCACG
GGCGGTCACGGACGGCGTCT

Downstream 100 bases:

>100_bases
GGCAGGGCCCGGGCCGGATGCGTCACGCGGAAACGAAGGCGAGGACGGAAAGAGATGCCGAGAAAGTCGCCGAACAGCGC
GCCGACCGTTTCACGCGAAG

Product: alpha/beta fold family hydrolase

Products: NA

Alternate protein names: Bacilysocin biosynthesis protein ytpA [H]

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MIEPILHHDTPETPVMDAAASTSPGLAADPGSAPRRGRLRTADGLELASYRWPAAGLSPAAPRATVALVHGLAEHAGRYQ
ALAERLNAAGIEVVAIDLRGHGHSPGERAWVERFDQYLEDADALVASVARDDTPLFLMGHSMGGAVAALYAVERAAVRRP
GLTGLILSSPALAPGRDVPRWMLAMSRFISRVWPRFPAIKIDAALLSRDPAVVAANRADPLVHHGPVPARTGAEILDAMR
RIEAGRAALRVPVLVYHGTADKLTEPDGSRDFGRHVGSPDRTLTLYEGNYHETMNDLERERVIGAQIDWIAARAPARG

Sequences:

>Translated_318_residues
MIEPILHHDTPETPVMDAAASTSPGLAADPGSAPRRGRLRTADGLELASYRWPAAGLSPAAPRATVALVHGLAEHAGRYQ
ALAERLNAAGIEVVAIDLRGHGHSPGERAWVERFDQYLEDADALVASVARDDTPLFLMGHSMGGAVAALYAVERAAVRRP
GLTGLILSSPALAPGRDVPRWMLAMSRFISRVWPRFPAIKIDAALLSRDPAVVAANRADPLVHHGPVPARTGAEILDAMR
RIEAGRAALRVPVLVYHGTADKLTEPDGSRDFGRHVGSPDRTLTLYEGNYHETMNDLERERVIGAQIDWIAARAPARG
>Mature_318_residues
MIEPILHHDTPETPVMDAAASTSPGLAADPGSAPRRGRLRTADGLELASYRWPAAGLSPAAPRATVALVHGLAEHAGRYQ
ALAERLNAAGIEVVAIDLRGHGHSPGERAWVERFDQYLEDADALVASVARDDTPLFLMGHSMGGAVAALYAVERAAVRRP
GLTGLILSSPALAPGRDVPRWMLAMSRFISRVWPRFPAIKIDAALLSRDPAVVAANRADPLVHHGPVPARTGAEILDAMR
RIEAGRAALRVPVLVYHGTADKLTEPDGSRDFGRHVGSPDRTLTLYEGNYHETMNDLERERVIGAQIDWIAARAPARG

Specific function: Phospholipase involved in the biosynthesis of the antibiotic bacilysocin. It probably catalyzes the hydrolysis of the 2-sn-acyl moiety of phosphatidylglycerol to produce bacilysocin (lysophosphatidylglycerol). Is also able to catalyze the hydrolysis react

COG id: COG2267

COG function: function code I; Lysophospholipase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily [H]

Homologues:

Organism=Homo sapiens, GI51242953, Length=297, Percent_Identity=34.006734006734, Blast_Score=147, Evalue=9e-36,
Organism=Homo sapiens, GI6005786, Length=297, Percent_Identity=34.006734006734, Blast_Score=147, Evalue=1e-35,
Organism=Escherichia coli, GI1787678, Length=270, Percent_Identity=27.037037037037, Blast_Score=75, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR022742 [H]

Pfam domain/function: PF12146 Hydrolase_4 [H]

EC number: NA

Molecular weight: Translated: 34129; Mature: 34129

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: PS00120 LIPASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEPILHHDTPETPVMDAAASTSPGLAADPGSAPRRGRLRTADGLELASYRWPAAGLSPA
CCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCC
APRATVALVHGLAEHAGRYQALAERLNAAGIEVVAIDLRGHGHSPGERAWVERFDQYLED
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHH
ADALVASVARDDTPLFLMGHSMGGAVAALYAVERAAVRRPGLTGLILSSPALAPGRDVPR
HHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCHH
WMLAMSRFISRVWPRFPAIKIDAALLSRDPAVVAANRADPLVHHGPVPARTGAEILDAMR
HHHHHHHHHHHHCCCCCCEEEHHHHHCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHH
RIEAGRAALRVPVLVYHGTADKLTEPDGSRDFGRHVGSPDRTLTLYEGNYHETMNDLERE
HHHHCCCEEEEEEEEEECCHHHCCCCCCCHHHHHHCCCCCCEEEEEECCHHHHHHHHHHH
RVIGAQIDWIAARAPARG
HHHCCCHHHHCCCCCCCC
>Mature Secondary Structure
MIEPILHHDTPETPVMDAAASTSPGLAADPGSAPRRGRLRTADGLELASYRWPAAGLSPA
CCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCC
APRATVALVHGLAEHAGRYQALAERLNAAGIEVVAIDLRGHGHSPGERAWVERFDQYLED
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHH
ADALVASVARDDTPLFLMGHSMGGAVAALYAVERAAVRRPGLTGLILSSPALAPGRDVPR
HHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCHH
WMLAMSRFISRVWPRFPAIKIDAALLSRDPAVVAANRADPLVHHGPVPARTGAEILDAMR
HHHHHHHHHHHHCCCCCCEEEHHHHHCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHH
RIEAGRAALRVPVLVYHGTADKLTEPDGSRDFGRHVGSPDRTLTLYEGNYHETMNDLERE
HHHHCCCEEEEEEEEEECCHHHCCCCCCCHHHHHHCCCCCCEEEEEECCHHHHHHHHHHH
RVIGAQIDWIAARAPARG
HHHCCCHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377 [H]