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The map label for this gene is ygfU [H]

Identifier: 83591294

GI number: 83591294

Start: 2584369

End: 2585664

Strand: Reverse

Name: ygfU [H]

Synonym: Moth_2478

Alternate gene names: 83591294

Gene position: 2585664-2584369 (Counterclockwise)

Preceding gene: 83591295

Following gene: 83591293

Centisome position: 98.36

GC content: 46.06

Gene sequence:

>1296_bases
ATGTTACCGACCGGACAACTTTTTCTGTACGGGTTACAGCATGTACTGGCTATGTATGCTGGAGCTGTCGCTGTACCGCT
GATCATTGCCGGTGCTGCTCACTTAACGAAAGCGGAAACGGCGTTTTTAATCAATGCCGATATGTTTACCTGCGGTATTG
CGACTTTGATTCAAACCCTTGGCTTCTGGAAACTGGGTATCCGTTTACCAGTCATTCAAGGAGTTTCCTTTGCCGCTGTA
GCACCCATGGTTATTATCGCCAGGAGCATGGGGATGGAAGCTGTTTATGGTGCGGTAATAGTTGCCGGTCTGATTGCGTT
TTTCCTTGCGCCTTATTTTAGCAAGCTTTTGCATTTCTTTCCCCCAGTTGTCACCGGCAGTGTAATAACTATTATTGGAA
TATCCTTGCTTCCGGTTGGTGTGGAATGGGCTGCTGGAGGCACAGGTAATGCAAATTACGGGGCGCTAACTAATCTTTTT
ATAGCAGGAATTGTCCTTCTGGCCATTCTTTTGATCCAAAAGTATTTTAAAGGCTTTATTGCCAATATTTCCGTCTTATT
AGGTCTATTTATCGGTATGCTTATTGCAATTCCCCTGGGCTTGGTCAACTTTTCCGGCGTAACCACAGCCCCCTGGTTGG
GAATCGACAGACCATTTTATTTCGGATTCCCCAAGTTTGATTGGGGAGCTATTGGAGCCATGATACTGGTTATGCTGGTA
ACGATGGTGGAATCCACAGGTGATTTCTTGGCCCTGGGGGAGATTGTTGGTAAGCAAATCGATGAAGAAGATTTAGCGCG
GGGCTTAAGAGGCGATGGGTTTGCCACCATGCTCGGTGGGGTACTGAATGCCTTCCCCTATACTGCCTTTGCACAAAACG
TTGGACTGGTAGGTTTGAGTGGCGTGAAAAGTCGTTTTGTAGTGGCAACATCTGGTATTATTCTGGCTGCCCTGGGATTA
TTTCCGAAACTGGCCACTATCATTGCCTCCATACCTTATGCTGTTTTGGGGGGAGCCGGTATTGCCATGTTCGGGGTTGT
GGCAGCCAACGGGATAAAAACCCTTTCTCGCGTTGATTTCGAAAACAACCCCCATAATATCTTCATCGTGGCCATTAGTA
TAGGTGTTGGCCTGATCCCAATGGTTGCACCAGACTTCTTCAAAATGTTCCCCGCCTGGAGTCAGATTATACTCCACAGT
GGTATTACTCTTGGCTCCTTAACTGCGATCATTCTCAACATTTTCTTTAACTATCCCAACTCATTAACGTTGTATAAAAA
GTCTTTCACTAATTGA

Upstream 100 bases:

>100_bases
AACTACAATTTATTAACCCCAATGCCCATCAACTAGAACTTTACAGAGATCATCCTGCAGGGGGAGATGCTAATTGTAAA
CAAAACATTCGGTTGATCAA

Downstream 100 bases:

>100_bases
TCCGGTTCCCCTTGATCAAGGTCCACCTGGGATCCCGGCTCATTCCCGGTTATGGGCTCCGGAATAATTTCGGCTGTCCG
CCGGGCTTTCTTTTTGGTTA

Product: uracil-xanthine permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 431; Mature: 431

Protein sequence:

>431_residues
MLPTGQLFLYGLQHVLAMYAGAVAVPLIIAGAAHLTKAETAFLINADMFTCGIATLIQTLGFWKLGIRLPVIQGVSFAAV
APMVIIARSMGMEAVYGAVIVAGLIAFFLAPYFSKLLHFFPPVVTGSVITIIGISLLPVGVEWAAGGTGNANYGALTNLF
IAGIVLLAILLIQKYFKGFIANISVLLGLFIGMLIAIPLGLVNFSGVTTAPWLGIDRPFYFGFPKFDWGAIGAMILVMLV
TMVESTGDFLALGEIVGKQIDEEDLARGLRGDGFATMLGGVLNAFPYTAFAQNVGLVGLSGVKSRFVVATSGIILAALGL
FPKLATIIASIPYAVLGGAGIAMFGVVAANGIKTLSRVDFENNPHNIFIVAISIGVGLIPMVAPDFFKMFPAWSQIILHS
GITLGSLTAIILNIFFNYPNSLTLYKKSFTN

Sequences:

>Translated_431_residues
MLPTGQLFLYGLQHVLAMYAGAVAVPLIIAGAAHLTKAETAFLINADMFTCGIATLIQTLGFWKLGIRLPVIQGVSFAAV
APMVIIARSMGMEAVYGAVIVAGLIAFFLAPYFSKLLHFFPPVVTGSVITIIGISLLPVGVEWAAGGTGNANYGALTNLF
IAGIVLLAILLIQKYFKGFIANISVLLGLFIGMLIAIPLGLVNFSGVTTAPWLGIDRPFYFGFPKFDWGAIGAMILVMLV
TMVESTGDFLALGEIVGKQIDEEDLARGLRGDGFATMLGGVLNAFPYTAFAQNVGLVGLSGVKSRFVVATSGIILAALGL
FPKLATIIASIPYAVLGGAGIAMFGVVAANGIKTLSRVDFENNPHNIFIVAISIGVGLIPMVAPDFFKMFPAWSQIILHS
GITLGSLTAIILNIFFNYPNSLTLYKKSFTN
>Mature_431_residues
MLPTGQLFLYGLQHVLAMYAGAVAVPLIIAGAAHLTKAETAFLINADMFTCGIATLIQTLGFWKLGIRLPVIQGVSFAAV
APMVIIARSMGMEAVYGAVIVAGLIAFFLAPYFSKLLHFFPPVVTGSVITIIGISLLPVGVEWAAGGTGNANYGALTNLF
IAGIVLLAILLIQKYFKGFIANISVLLGLFIGMLIAIPLGLVNFSGVTTAPWLGIDRPFYFGFPKFDWGAIGAMILVMLV
TMVESTGDFLALGEIVGKQIDEEDLARGLRGDGFATMLGGVLNAFPYTAFAQNVGLVGLSGVKSRFVVATSGIILAALGL
FPKLATIIASIPYAVLGGAGIAMFGVVAANGIKTLSRVDFENNPHNIFIVAISIGVGLIPMVAPDFFKMFPAWSQIILHS
GITLGSLTAIILNIFFNYPNSLTLYKKSFTN

Specific function: Unknown

COG id: COG2233

COG function: function code F; Xanthine/uracil permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily [H]

Homologues:

Organism=Homo sapiens, GI44680143, Length=454, Percent_Identity=24.8898678414097, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI44680145, Length=455, Percent_Identity=24.3956043956044, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI222080105, Length=479, Percent_Identity=24.4258872651357, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI44680148, Length=451, Percent_Identity=23.2815964523282, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI40316845, Length=451, Percent_Identity=23.2815964523282, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI222080107, Length=487, Percent_Identity=24.435318275154, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI87082181, Length=435, Percent_Identity=50.3448275862069, Blast_Score=412, Evalue=1e-116,
Organism=Escherichia coli, GI1790087, Length=431, Percent_Identity=30.6264501160093, Blast_Score=183, Evalue=2e-47,
Organism=Escherichia coli, GI87082178, Length=443, Percent_Identity=30.2483069977427, Blast_Score=168, Evalue=6e-43,
Organism=Escherichia coli, GI1788843, Length=390, Percent_Identity=28.7179487179487, Blast_Score=125, Evalue=6e-30,
Organism=Escherichia coli, GI87081818, Length=397, Percent_Identity=28.9672544080605, Blast_Score=122, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI17541904, Length=427, Percent_Identity=25.0585480093677, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17558856, Length=223, Percent_Identity=26.0089686098655, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17542260, Length=197, Percent_Identity=27.9187817258883, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71993493, Length=197, Percent_Identity=27.4111675126904, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17542262, Length=436, Percent_Identity=23.394495412844, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21356175, Length=433, Percent_Identity=26.0969976905312, Blast_Score=92, Evalue=7e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017588
- InterPro:   IPR006042
- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 45451; Mature: 45451

Theoretical pI: Translated: 9.15; Mature: 9.15

Prosite motif: PS01116 XANTH_URACIL_PERMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPTGQLFLYGLQHVLAMYAGAVAVPLIIAGAAHLTKAETAFLINADMFTCGIATLIQTL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECHHHHHHHHHHHHHH
GFWKLGIRLPVIQGVSFAAVAPMVIIARSMGMEAVYGAVIVAGLIAFFLAPYFSKLLHFF
HHHHHCCCCHHHCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PPVVTGSVITIIGISLLPVGVEWAAGGTGNANYGALTNLFIAGIVLLAILLIQKYFKGFI
CHHHHCHHHHHHHHHHHCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ANISVLLGLFIGMLIAIPLGLVNFSGVTTAPWLGIDRPFYFGFPKFDWGAIGAMILVMLV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEECCCCCCCHHHHHHHHHHHHH
TMVESTGDFLALGEIVGKQIDEEDLARGLRGDGFATMLGGVLNAFPYTAFAQNVGLVGLS
HHHHCCCCHHHHHHHHCCCCCHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHCCCCEEEC
GVKSRFVVATSGIILAALGLFPKLATIIASIPYAVLGGAGIAMFGVVAANGIKTLSRVDF
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHCCC
ENNPHNIFIVAISIGVGLIPMVAPDFFKMFPAWSQIILHSGITLGSLTAIILNIFFNYPN
CCCCCEEEEEEEECCCCHHHHHCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCC
SLTLYKKSFTN
CEEEECCCCCC
>Mature Secondary Structure
MLPTGQLFLYGLQHVLAMYAGAVAVPLIIAGAAHLTKAETAFLINADMFTCGIATLIQTL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECHHHHHHHHHHHHHH
GFWKLGIRLPVIQGVSFAAVAPMVIIARSMGMEAVYGAVIVAGLIAFFLAPYFSKLLHFF
HHHHHCCCCHHHCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PPVVTGSVITIIGISLLPVGVEWAAGGTGNANYGALTNLFIAGIVLLAILLIQKYFKGFI
CHHHHCHHHHHHHHHHHCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ANISVLLGLFIGMLIAIPLGLVNFSGVTTAPWLGIDRPFYFGFPKFDWGAIGAMILVMLV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEECCCCCCCHHHHHHHHHHHHH
TMVESTGDFLALGEIVGKQIDEEDLARGLRGDGFATMLGGVLNAFPYTAFAQNVGLVGLS
HHHHCCCCHHHHHHHHCCCCCHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHCCCCEEEC
GVKSRFVVATSGIILAALGLFPKLATIIASIPYAVLGGAGIAMFGVVAANGIKTLSRVDF
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHCCC
ENNPHNIFIVAISIGVGLIPMVAPDFFKMFPAWSQIILHSGITLGSLTAIILNIFFNYPN
CCCCCEEEEEEEECCCCHHHHHCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCC
SLTLYKKSFTN
CEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]