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The map label for this gene is engD [H]

Identifier: 83591293

GI number: 83591293

Start: 2583112

End: 2584185

Strand: Reverse

Name: engD [H]

Synonym: Moth_2477

Alternate gene names: 83591293

Gene position: 2584185-2583112 (Counterclockwise)

Preceding gene: 83591294

Following gene: 83591291

Centisome position: 98.3

GC content: 57.91

Gene sequence:

>1074_bases
TTGCCCCTGACCTGTGGTATTATTGGTTTACCCCTGGTAGGCAAAACGACCCTGTTTAACCTTTTAACCCAGGCTGAGGC
GGAAACCTCGGCCTTTGCCGGCCGTACTAAAACCAACATCCGGACGGCGCCCATACCCGATGCCCGCCTGGATTTCCTGG
CGGCCCTTTACCATCCCCGCAAGGTTACCCCCGCCACCTTGGAGATTATCGATGTCCCGGGGTTGACCCGGGGGGCCGGT
GCGGCCTTCCTGGCCGCTGTCCGGGAAGTAGACGCCCTGATCCATGTAGTCCGGGCCTTTCGGAACGATAGTATAATCCA
CGTAGAAGGTAACCTCAACCCGGTGCGGGACCTGGAGACTATTAATGCCGAGCTCCTCCTGGCCGATCTGCAACTGGTCG
AAACCCGTCTGGAGCGAATTGCCGCCAGCAAGAAAATCAAGCCGGAAATGCAGGCCGAACGGGAGGCCCTGGAGCATTGC
CGCCAAGCCCTGGAAGCCGAAAAGCCCCTGCTGGAAGCCGGCCTAACGGAAGAGGAATGGCAGACCCTGCGCCATATGGG
CTTTTTGACAACTAAGCCCATGATCATAGTGGTCAATATCGATGAAGACCAGCTCCGCTCCGGGCATTATGCCGGTGAAG
AAGAGGTCAAGGCCTATGCCCAACCGAAGGGTTTACCGATATTGACTCTCTGCGCCGAACTGGAAGCGGAGATTGCCCGC
CTGGAACCGGGCGACAGGGAAGACTTCCTGCGGGAAATGGGCATTACCGAACCGGGCATCGACCGTCTGGCCCGGGCCAT
TTACCACCGCCTGGGATTAATCTCTTTCTTAACCGCTGGCGAAGACGAAGTCCGGGCCTGGACCATCCAGGCCGGCACCA
ACGCCCGGGCGGCGGCCGGTAAAATCCATAGCGATATCGAGCGAGGCTTTATCCGCGCCGAGGTGGTTAACTTTGCCGAC
CTGGAGCGGTGCGGCAATATGAATAAAGTCAAGGAACAAGGTCTGGCGCGCCTGGAAGGCAAGGATTATATTGTGCAGGA
CGGCGATATCATCAACTTCCGCTTTAATGTTTAG

Upstream 100 bases:

>100_bases
GGCTTTCTTTTTGGTTAATCTAGATTAGCCTCGCCGGTGTCCCGAGATGGCCTTCCCTTTTGCTATCTGAACTGATATAC
TTGAGCCGAGGTGAAGTAAA

Downstream 100 bases:

>100_bases
TTAATCTTTATCACCCCCCTGAACGGGGGATTTTTTATTTGGTAACTTGTGAAGGGAAAGCCACATAAAATACCAGTAGC
CAGTTAAATGGCTATGTTGT

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 357; Mature: 356

Protein sequence:

>357_residues
MPLTCGIIGLPLVGKTTLFNLLTQAEAETSAFAGRTKTNIRTAPIPDARLDFLAALYHPRKVTPATLEIIDVPGLTRGAG
AAFLAAVREVDALIHVVRAFRNDSIIHVEGNLNPVRDLETINAELLLADLQLVETRLERIAASKKIKPEMQAEREALEHC
RQALEAEKPLLEAGLTEEEWQTLRHMGFLTTKPMIIVVNIDEDQLRSGHYAGEEEVKAYAQPKGLPILTLCAELEAEIAR
LEPGDREDFLREMGITEPGIDRLARAIYHRLGLISFLTAGEDEVRAWTIQAGTNARAAAGKIHSDIERGFIRAEVVNFAD
LERCGNMNKVKEQGLARLEGKDYIVQDGDIINFRFNV

Sequences:

>Translated_357_residues
MPLTCGIIGLPLVGKTTLFNLLTQAEAETSAFAGRTKTNIRTAPIPDARLDFLAALYHPRKVTPATLEIIDVPGLTRGAG
AAFLAAVREVDALIHVVRAFRNDSIIHVEGNLNPVRDLETINAELLLADLQLVETRLERIAASKKIKPEMQAEREALEHC
RQALEAEKPLLEAGLTEEEWQTLRHMGFLTTKPMIIVVNIDEDQLRSGHYAGEEEVKAYAQPKGLPILTLCAELEAEIAR
LEPGDREDFLREMGITEPGIDRLARAIYHRLGLISFLTAGEDEVRAWTIQAGTNARAAAGKIHSDIERGFIRAEVVNFAD
LERCGNMNKVKEQGLARLEGKDYIVQDGDIINFRFNV
>Mature_356_residues
PLTCGIIGLPLVGKTTLFNLLTQAEAETSAFAGRTKTNIRTAPIPDARLDFLAALYHPRKVTPATLEIIDVPGLTRGAGA
AFLAAVREVDALIHVVRAFRNDSIIHVEGNLNPVRDLETINAELLLADLQLVETRLERIAASKKIKPEMQAEREALEHCR
QALEAEKPLLEAGLTEEEWQTLRHMGFLTTKPMIIVVNIDEDQLRSGHYAGEEEVKAYAQPKGLPILTLCAELEAEIARL
EPGDREDFLREMGITEPGIDRLARAIYHRLGLISFLTAGEDEVRAWTIQAGTNARAAAGKIHSDIERGFIRAEVVNFADL
ERCGNMNKVKEQGLARLEGKDYIVQDGDIINFRFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=376, Percent_Identity=38.563829787234, Blast_Score=244, Evalue=1e-64,
Organism=Homo sapiens, GI58761502, Length=232, Percent_Identity=37.5, Blast_Score=135, Evalue=8e-32,
Organism=Escherichia coli, GI1787454, Length=365, Percent_Identity=44.1095890410959, Blast_Score=303, Evalue=9e-84,
Organism=Caenorhabditis elegans, GI17509631, Length=368, Percent_Identity=39.4021739130435, Blast_Score=253, Evalue=8e-68,
Organism=Saccharomyces cerevisiae, GI6319499, Length=376, Percent_Identity=35.9042553191489, Blast_Score=193, Evalue=3e-50,
Organism=Saccharomyces cerevisiae, GI6321773, Length=380, Percent_Identity=33.4210526315789, Blast_Score=180, Evalue=4e-46,
Organism=Drosophila melanogaster, GI24640873, Length=375, Percent_Identity=36.8, Blast_Score=216, Evalue=2e-56,
Organism=Drosophila melanogaster, GI24640877, Length=375, Percent_Identity=36.8, Blast_Score=216, Evalue=2e-56,
Organism=Drosophila melanogaster, GI24640875, Length=375, Percent_Identity=36.8, Blast_Score=216, Evalue=2e-56,
Organism=Drosophila melanogaster, GI24640879, Length=336, Percent_Identity=35.7142857142857, Blast_Score=188, Evalue=5e-48,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 39542; Mature: 39411

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLTCGIIGLPLVGKTTLFNLLTQAEAETSAFAGRTKTNIRTAPIPDARLDFLAALYHPR
CCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCHHHHHHHHHHCCC
KVTPATLEIIDVPGLTRGAGAAFLAAVREVDALIHVVRAFRNDSIIHVEGNLNPVRDLET
CCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHH
INAELLLADLQLVETRLERIAASKKIKPEMQAEREALEHCRQALEAEKPLLEAGLTEEEW
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHH
QTLRHMGFLTTKPMIIVVNIDEDQLRSGHYAGEEEVKAYAQPKGLPILTLCAELEAEIAR
HHHHHHCCEECCCEEEEEECCHHHHHCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHH
LEPGDREDFLREMGITEPGIDRLARAIYHRLGLISFLTAGEDEVRAWTIQAGTNARAAAG
CCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHH
KIHSDIERGFIRAEVVNFADLERCGNMNKVKEQGLARLEGKDYIVQDGDIINFRFNV
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEECCCEEEEEECC
>Mature Secondary Structure 
PLTCGIIGLPLVGKTTLFNLLTQAEAETSAFAGRTKTNIRTAPIPDARLDFLAALYHPR
CCCCCEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCHHHHHHHHHHCCC
KVTPATLEIIDVPGLTRGAGAAFLAAVREVDALIHVVRAFRNDSIIHVEGNLNPVRDLET
CCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHH
INAELLLADLQLVETRLERIAASKKIKPEMQAEREALEHCRQALEAEKPLLEAGLTEEEW
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHH
QTLRHMGFLTTKPMIIVVNIDEDQLRSGHYAGEEEVKAYAQPKGLPILTLCAELEAEIAR
HHHHHHCCEECCCEEEEEECCHHHHHCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHH
LEPGDREDFLREMGITEPGIDRLARAIYHRLGLISFLTAGEDEVRAWTIQAGTNARAAAG
CCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHH
KIHSDIERGFIRAEVVNFADLERCGNMNKVKEQGLARLEGKDYIVQDGDIINFRFNV
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEECCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]