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The map label for this gene is hypB [H]

Identifier: 83591003

GI number: 83591003

Start: 2280283

End: 2280936

Strand: Reverse

Name: hypB [H]

Synonym: Moth_2180

Alternate gene names: 83591003

Gene position: 2280936-2280283 (Counterclockwise)

Preceding gene: 83591004

Following gene: 83591002

Centisome position: 86.77

GC content: 50.31

Gene sequence:

>654_bases
ATGGCTCAAAAAATTCTCCAGGCTAACGAAGAAATCGCGGAACAGAATCGCAAGCTTCTCGACAGGATATTAACCGTTAA
CTTGATTAGTTCGCCCGGTGCGGGTAAAACCACCCTCCTGGAAAGAACGATAGCTTCGTTAAAGAAGGATCTTGCCATAG
GAGTAATTGAGGGTGATATATCCACCACCCTTGATGCCGAGCGCATTGCCGGGCAAGGGGTGGAAGTAGTCCAGATCAAT
ACAGAAGGAGCTTGTCACCTGGATGCCAGGTTGATTTCTAAAGCACTGCAGGAGCTCGACCTCTCCGGCCTGGACCTTAT
ATTTATCGAAAACGTAGGCAACCTGGTATGCCCGGCCGAATTCGACCTGGGAGAGGATTATAAGGTGGCCCTGCTGAGCG
TTACTGAAGGCAGCGACAAGCCCGCCAAGTACCCCCTGGTGTTTCACGAAGCCAGGGCAATGGTCATTACCAAAGGGGAC
CTCTTGCCGTATACTGACTTTGACTTGAAAGCAGTCGAAGAAGAGATTAAGGCAGCCAATCCTGCTGCGAAGTTTTTCGT
AACCTCAGCTAAAACCGGCGAGGGCCTGGAGGCTTGGTGTTTATGGCTCAAAGAAGCAATGCAGAGAAAAAGGGGATTGT
CCGCTATCGGATAA

Upstream 100 bases:

>100_bases
TCATTGAAGGAAAAGAATTTTATATTGACTTTTATGAAGGGGAATGAATTCAAGGGGAACCCTTTAAACGGATGGAGGGA
ATATCAAATTGAAGGTAGTA

Downstream 100 bases:

>100_bases
TCGTCAAAGGGATCGTCCAGGGCGTAGGGTTTCGCCCCTTTATTTATAACCTGGCGAGGCTCTATCGCCTGAAGGGCACT
GTTGCCAATACCAGCCAGGG

Product: hydrogenase accessory protein HypB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 217; Mature: 216

Protein sequence:

>217_residues
MAQKILQANEEIAEQNRKLLDRILTVNLISSPGAGKTTLLERTIASLKKDLAIGVIEGDISTTLDAERIAGQGVEVVQIN
TEGACHLDARLISKALQELDLSGLDLIFIENVGNLVCPAEFDLGEDYKVALLSVTEGSDKPAKYPLVFHEARAMVITKGD
LLPYTDFDLKAVEEEIKAANPAAKFFVTSAKTGEGLEAWCLWLKEAMQRKRGLSAIG

Sequences:

>Translated_217_residues
MAQKILQANEEIAEQNRKLLDRILTVNLISSPGAGKTTLLERTIASLKKDLAIGVIEGDISTTLDAERIAGQGVEVVQIN
TEGACHLDARLISKALQELDLSGLDLIFIENVGNLVCPAEFDLGEDYKVALLSVTEGSDKPAKYPLVFHEARAMVITKGD
LLPYTDFDLKAVEEEIKAANPAAKFFVTSAKTGEGLEAWCLWLKEAMQRKRGLSAIG
>Mature_216_residues
AQKILQANEEIAEQNRKLLDRILTVNLISSPGAGKTTLLERTIASLKKDLAIGVIEGDISTTLDAERIAGQGVEVVQINT
EGACHLDARLISKALQELDLSGLDLIFIENVGNLVCPAEFDLGEDYKVALLSVTEGSDKPAKYPLVFHEARAMVITKGDL
LPYTDFDLKAVEEEIKAANPAAKFFVTSAKTGEGLEAWCLWLKEAMQRKRGLSAIG

Specific function: Could be involved in nickel binding and accumulation [H]

COG id: COG0378

COG function: function code OK; Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypB/hupM family [H]

Homologues:

Organism=Escherichia coli, GI1789082, Length=202, Percent_Identity=48.5148514851485, Blast_Score=195, Evalue=2e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003495
- InterPro:   IPR004392
- InterPro:   IPR012202 [H]

Pfam domain/function: PF02492 cobW [H]

EC number: NA

Molecular weight: Translated: 23552; Mature: 23421

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQKILQANEEIAEQNRKLLDRILTVNLISSPGAGKTTLLERTIASLKKDLAIGVIEGDI
CCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHEEEEEECCC
STTLDAERIAGQGVEVVQINTEGACHLDARLISKALQELDLSGLDLIFIENVGNLVCPAE
HHCCCHHHHCCCCEEEEEEECCCCEEHHHHHHHHHHHHCCCCCCEEEEEECCCCEECCCC
FDLGEDYKVALLSVTEGSDKPAKYPLVFHEARAMVITKGDLLPYTDFDLKAVEEEIKAAN
CCCCCCCEEEEEEEECCCCCCCCCCEEEECCEEEEEECCCCCCCCCCHHHHHHHHHHHCC
PAAKFFVTSAKTGEGLEAWCLWLKEAMQRKRGLSAIG
CCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
AQKILQANEEIAEQNRKLLDRILTVNLISSPGAGKTTLLERTIASLKKDLAIGVIEGDI
CCHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHEEEEEECCC
STTLDAERIAGQGVEVVQINTEGACHLDARLISKALQELDLSGLDLIFIENVGNLVCPAE
HHCCCHHHHCCCCEEEEEEECCCCEEHHHHHHHHHHHHCCCCCCEEEEEECCCCEECCCC
FDLGEDYKVALLSVTEGSDKPAKYPLVFHEARAMVITKGDLLPYTDFDLKAVEEEIKAAN
CCCCCCCEEEEEEEECCCCCCCCCCEEEECCEEEEEECCCCCCCCCCHHHHHHHHHHHCC
PAAKFFVTSAKTGEGLEAWCLWLKEAMQRKRGLSAIG
CCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8486288 [H]