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The map label for this gene is hypA

Identifier: 83591004

GI number: 83591004

Start: 2280990

End: 2281331

Strand: Reverse

Name: hypA

Synonym: Moth_2181

Alternate gene names: 83591004

Gene position: 2281331-2280990 (Counterclockwise)

Preceding gene: 83591005

Following gene: 83591003

Centisome position: 86.78

GC content: 45.32

Gene sequence:

>342_bases
ATGCATGAGCTGGCCCTGACGGCGGAGTTACTCAGGTTGTTAGAGAACAATGCGCGCGAGAAAGGTATAAAGCATATCAA
GAGAGTAAAGCTGGTGATAGGAGCATTGAGTTCAGTGCTGCCGGAGGCCGTAGAGTTTTCTTTTAACACCCTGAAGGAAG
GACCATTATTTGAAGATGCTAAGTTAGAAATTGAGGAAAAGCCGGTCCGGATCCGCTGCAGGGACTGTATGGCTGAAAAA
GCCGTGGATCACTTTTATCCTCTATGCCCTTCCTGTGGGTCAGGAAGGGTTTCTATCATTGAAGGAAAAGAATTTTATAT
TGACTTTTATGAAGGGGAATGA

Upstream 100 bases:

>100_bases
GTTTCGCCTGAAGTAAAACAAGCCGTTGAGACTGTATATCAAAAGCTGCAGGCCGGGAAGCTCGATTTTCAATGTCTTGG
ACAGTTAGGAGAGAAAGAAG

Downstream 100 bases:

>100_bases
ATTCAAGGGGAACCCTTTAAACGGATGGAGGGAATATCAAATTGAAGGTAGTAATGGCTCAAAAAATTCTCCAGGCTAAC
GAAGAAATCGCGGAACAGAA

Product: hydrogenase nickel insertion protein HypA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 113; Mature: 113

Protein sequence:

>113_residues
MHELALTAELLRLLENNAREKGIKHIKRVKLVIGALSSVLPEAVEFSFNTLKEGPLFEDAKLEIEEKPVRIRCRDCMAEK
AVDHFYPLCPSCGSGRVSIIEGKEFYIDFYEGE

Sequences:

>Translated_113_residues
MHELALTAELLRLLENNAREKGIKHIKRVKLVIGALSSVLPEAVEFSFNTLKEGPLFEDAKLEIEEKPVRIRCRDCMAEK
AVDHFYPLCPSCGSGRVSIIEGKEFYIDFYEGE
>Mature_113_residues
MHELALTAELLRLLENNAREKGIKHIKRVKLVIGALSSVLPEAVEFSFNTLKEGPLFEDAKLEIEEKPVRIRCRDCMAEK
AVDHFYPLCPSCGSGRVSIIEGKEFYIDFYEGE

Specific function: Probably plays a role in an hydrogenase nickel cofactor insertion step

COG id: COG0375

COG function: function code R; Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypA/hybF family

Homologues:

Organism=Escherichia coli, GI1789365, Length=113, Percent_Identity=30.9734513274336, Blast_Score=63, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HYPA_MOOTA (Q2RGG9)

Other databases:

- EMBL:   CP000232
- RefSeq:   YP_431013.1
- STRING:   Q2RGG9
- GeneID:   3831651
- GenomeReviews:   CP000232_GR
- KEGG:   mta:Moth_2181
- NMPDR:   fig|264732.9.peg.2207
- eggNOG:   COG0375
- HOGENOM:   HBG688671
- OMA:   HETALME
- PhylomeDB:   Q2RGG9
- ProtClustDB:   CLSK941273
- BioCyc:   MTHE264732:MOTH_2181-MONOMER
- HAMAP:   MF_00213
- InterPro:   IPR000688
- TIGRFAMs:   TIGR00100

Pfam domain/function: PF01155 HypA

EC number: NA

Molecular weight: Translated: 12841; Mature: 12841

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: PS01249 HYPA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHELALTAELLRLLENNAREKGIKHIKRVKLVIGALSSVLPEAVEFSFNTLKEGPLFEDA
CCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
KLEIEEKPVRIRCRDCMAEKAVDHFYPLCPSCGSGRVSIIEGKEFYIDFYEGE
CCEECCCCEEEHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCEEEEEEECCC
>Mature Secondary Structure
MHELALTAELLRLLENNAREKGIKHIKRVKLVIGALSSVLPEAVEFSFNTLKEGPLFEDA
CCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
KLEIEEKPVRIRCRDCMAEKAVDHFYPLCPSCGSGRVSIIEGKEFYIDFYEGE
CCEECCCCEEEHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA