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The map label for this gene is hypD [H]

Identifier: 83591000

GI number: 83591000

Start: 2276690

End: 2277823

Strand: Reverse

Name: hypD [H]

Synonym: Moth_2177

Alternate gene names: 83591000

Gene position: 2277823-2276690 (Counterclockwise)

Preceding gene: 83591001

Following gene: 83590999

Centisome position: 86.65

GC content: 55.2

Gene sequence:

>1134_bases
ATGTCACCCCTGGACAGGTTTTGTGATACGGAACTAAGCAGGAAACTCATGGGCCGGGTTGCCGCCCTGGCAGATGAGGT
TGCGGAACGCCTTGGGCGGCCGGCAGTTTTTATAGAAGTATGCGGTACACACACAGTGGCTATTTCCCGGCTGGGATTGC
GGAGCTTGCTGGCAGGTCGCGTAGAATTGCGAAGCGGCCCCGGGTGTCCTGTTTGTGTAACTGATCACCAGGAAATCGAT
ATGATGGTCGATCTGGCCCGCCTGCCCGGGGTTACGCTGGGAACCTTCGGGGATATGTTACGCGTTCCCGGCAGCCGGTC
TTCCCTGGAGAGGGAACGCGCCGGCGGTGCCGACGTGCGCATTTTTTACTCGCCCCTGGACGCAGTGGCCTTTGCTGAAG
CCAACCCGGAAAGAGAGGTCGTGTTTTTAGGGATTGGTTTTGAAACGACTGCCCCGGCAGTCGCTGCAAGCCTTGCGAGG
GCCCGGGCTAAAGGGGTGAAAAACTTTAGTCTATTTTCGGCCCATAAACTCATCCCCCCGGCCCTTCGCGCCGTTCTCAG
TGACCCCGAATTAAAACTGGACGGGCTTATCTTGCCGGGTCATGTTAGCGCCGTTACTGGCAGGCGGGCGTTTGACTTTA
TCGTTAAAGAGTATGGCCTGCCGTCAGTAATCAGCGGCTTTGACCCCATGGATATTCTGATTGCCCTTCACGAGCTTTTG
CTTCAATTGCTCCGGGGCGAGGCCCGGGTTGCCAACAAGTACACGCGGGTAGTGCGGGAAGAAGGTAACCTGGATGCTCG
CAAGCGCATTGCGGAGTGTTTCGAGGAGGTCGATGTCCCCTGGCGCGGCCTTGGAGTTATTCCTGAAAGCGGACTTTCAC
TACGGGAAACTTTTCGGGATTTTGATGCCCGATTTAAACTAAATATAGAACCGGCCCCGCCAACACCTCTTTACCCGCCA
GGTTGTGCCTGTAAAGAAATTTTACGGGGAAAACTTTTACCCCCGGAATGCCGGCTATTTAGTAATGTATGTACACCTGT
CCATCCTGTAGGCCCCTGTATGGTTTCCAGTGAAGGGGCCTGCGCGGCTTACTATCGATTTGAACGTTTTTCTCCAGTTG
GAGGTGGCATTTAG

Upstream 100 bases:

>100_bases
GTTGGCGATTATGTGCTGGTTCATGCCGGATTTGCCATTGAAAAGATTGATTTAAAAGAAGCCGAACAGATGGTAAAAAT
GTGGGAGGAACAATTAAACG

Downstream 100 bases:

>100_bases
GATGAAAGAGAATGGCAGGGATATTGTTTTGCTGGCTCACGGTGACGGGGGTGCCCTTACCCATGAACTCATTAATAACC
TTTTTCTTCGTCACTTTGAA

Product: hydrogenase expression/formation protein HypD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 377; Mature: 376

Protein sequence:

>377_residues
MSPLDRFCDTELSRKLMGRVAALADEVAERLGRPAVFIEVCGTHTVAISRLGLRSLLAGRVELRSGPGCPVCVTDHQEID
MMVDLARLPGVTLGTFGDMLRVPGSRSSLERERAGGADVRIFYSPLDAVAFAEANPEREVVFLGIGFETTAPAVAASLAR
ARAKGVKNFSLFSAHKLIPPALRAVLSDPELKLDGLILPGHVSAVTGRRAFDFIVKEYGLPSVISGFDPMDILIALHELL
LQLLRGEARVANKYTRVVREEGNLDARKRIAECFEEVDVPWRGLGVIPESGLSLRETFRDFDARFKLNIEPAPPTPLYPP
GCACKEILRGKLLPPECRLFSNVCTPVHPVGPCMVSSEGACAAYYRFERFSPVGGGI

Sequences:

>Translated_377_residues
MSPLDRFCDTELSRKLMGRVAALADEVAERLGRPAVFIEVCGTHTVAISRLGLRSLLAGRVELRSGPGCPVCVTDHQEID
MMVDLARLPGVTLGTFGDMLRVPGSRSSLERERAGGADVRIFYSPLDAVAFAEANPEREVVFLGIGFETTAPAVAASLAR
ARAKGVKNFSLFSAHKLIPPALRAVLSDPELKLDGLILPGHVSAVTGRRAFDFIVKEYGLPSVISGFDPMDILIALHELL
LQLLRGEARVANKYTRVVREEGNLDARKRIAECFEEVDVPWRGLGVIPESGLSLRETFRDFDARFKLNIEPAPPTPLYPP
GCACKEILRGKLLPPECRLFSNVCTPVHPVGPCMVSSEGACAAYYRFERFSPVGGGI
>Mature_376_residues
SPLDRFCDTELSRKLMGRVAALADEVAERLGRPAVFIEVCGTHTVAISRLGLRSLLAGRVELRSGPGCPVCVTDHQEIDM
MVDLARLPGVTLGTFGDMLRVPGSRSSLERERAGGADVRIFYSPLDAVAFAEANPEREVVFLGIGFETTAPAVAASLARA
RAKGVKNFSLFSAHKLIPPALRAVLSDPELKLDGLILPGHVSAVTGRRAFDFIVKEYGLPSVISGFDPMDILIALHELLL
QLLRGEARVANKYTRVVREEGNLDARKRIAECFEEVDVPWRGLGVIPESGLSLRETFRDFDARFKLNIEPAPPTPLYPPG
CACKEILRGKLLPPECRLFSNVCTPVHPVGPCMVSSEGACAAYYRFERFSPVGGGI

Specific function: Required For The Formation Of All Three Hydrogenase Isoenzymes. [C]

COG id: COG0409

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypD family [H]

Homologues:

Organism=Escherichia coli, GI1789084, Length=370, Percent_Identity=43.2432432432432, Blast_Score=302, Evalue=2e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002780 [H]

Pfam domain/function: PF01924 HypD [H]

EC number: NA

Molecular weight: Translated: 40980; Mature: 40849

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPLDRFCDTELSRKLMGRVAALADEVAERLGRPAVFIEVCGTHTVAISRLGLRSLLAGR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHH
VELRSGPGCPVCVTDHQEIDMMVDLARLPGVTLGTFGDMLRVPGSRSSLERERAGGADVR
HHCCCCCCCCEEECCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHCCCCCEE
IFYSPLDAVAFAEANPEREVVFLGIGFETTAPAVAASLARARAKGVKNFSLFSAHKLIPP
EEECCHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHH
ALRAVLSDPELKLDGLILPGHVSAVTGRRAFDFIVKEYGLPSVISGFDPMDILIALHELL
HHHHHHCCCCCEECCEEECCCHHHHHCHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHH
LQLLRGEARVANKYTRVVREEGNLDARKRIAECFEEVDVPWRGLGVIPESGLSLRETFRD
HHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHH
FDARFKLNIEPAPPTPLYPPGCACKEILRGKLLPPECRLFSNVCTPVHPVGPCMVSSEGA
CCCEEEEEECCCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCEECCCCC
CAAYYRFERFSPVGGGI
EEEHHHHHHCCCCCCCC
>Mature Secondary Structure 
SPLDRFCDTELSRKLMGRVAALADEVAERLGRPAVFIEVCGTHTVAISRLGLRSLLAGR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHH
VELRSGPGCPVCVTDHQEIDMMVDLARLPGVTLGTFGDMLRVPGSRSSLERERAGGADVR
HHCCCCCCCCEEECCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHCCCCCEE
IFYSPLDAVAFAEANPEREVVFLGIGFETTAPAVAASLARARAKGVKNFSLFSAHKLIPP
EEECCHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHH
ALRAVLSDPELKLDGLILPGHVSAVTGRRAFDFIVKEYGLPSVISGFDPMDILIALHELL
HHHHHHCCCCCEECCEEECCCHHHHHCHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHH
LQLLRGEARVANKYTRVVREEGNLDARKRIAECFEEVDVPWRGLGVIPESGLSLRETFRD
HHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHH
FDARFKLNIEPAPPTPLYPPGCACKEILRGKLLPPECRLFSNVCTPVHPVGPCMVSSEGA
CCCEEEEEECCCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCEECCCCC
CAAYYRFERFSPVGGGI
EEEHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8497190 [H]