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The map label for this gene is hypE [H]

Identifier: 83590999

GI number: 83590999

Start: 2275672

End: 2276688

Strand: Reverse

Name: hypE [H]

Synonym: Moth_2176

Alternate gene names: 83590999

Gene position: 2276688-2275672 (Counterclockwise)

Preceding gene: 83591000

Following gene: 83590998

Centisome position: 86.61

GC content: 49.95

Gene sequence:

>1017_bases
ATGAAAGAGAATGGCAGGGATATTGTTTTGCTGGCTCACGGTGACGGGGGTGCCCTTACCCATGAACTCATTAATAACCT
TTTTCTTCGTCACTTTGAAAGCAATATCCTGAAAACGCTCACCGATGCGGCGGTTTTTTCCGGAAATGAAGGGAGAATGG
CCATCACTACGGATTCCTTTGTTGTCGATCCGCCTTTCTTCCCCGGGGGGGATGTGGGAAAACTGGCGGTTTGCGGTACG
GTAAATGATCTGGCGGTCAGCGGCGCCCGGCCCATCTATCTCACGGCTTCTTTTATTTTAGAAGAAGGACTGCCCCTTGC
CGATCTTGAAAGCATTGTCCAATCTATGGCCGGGGCCTGCGGGGTCGCGGGCGTAGAAATTATCACCGGGGATACCAAGG
TGGTTGAAAAAGGTCATTTAGATAAAATTTTTATTAACACCACCGGTGTCGGTTATATTTTTCCAGGAGTAGATTTGGGT
TACCACCGGATTAAACCCGGTGATAAAGTTTTAGTCAACGGCAGCCTCGGGCAACACGGTATCGCGGTACTTTGTAAACG
GTATGGCTTTGATTTTGCAGGACAGGTCGTGAGCGATTGTGCCCCGCTGAACGGCATAACCAGCCTGCTTTTAAAGGAAA
TCCGGGGGATCAAGATAATGCGGGATCTTACCCGGGGTGGCCTGGCAACAACCGCCAAAGAAATTGCGTCAGCCTGCGGT
TTAGATATCTGGCTGGACGAAAATTGTATTCCTGTCGATGCCGGGGTAAAGGGTGCCGCCGAGATGCTGGGACTGGATCC
CCTCTACCTTGCCAACGAGGGGAAGTTTATGGTTATTGTCAGCCCGGAAGAAGCAGAAAAAGCTGTAGCGGTAATGCAAG
GGCATGAATTGGGAAGGGATGCTAGTATTATAGGCGAAGTCAAACCTGGCAAGGGGAACGTTTATCTCTCCACCTCCCTT
GGAGGTACTAAACTCTTAGATCTTATGGCTGGAAGTCCTCTACCACGAATTTGTTGA

Upstream 100 bases:

>100_bases
CCTGTCCATCCTGTAGGCCCCTGTATGGTTTCCAGTGAAGGGGCCTGCGCGGCTTACTATCGATTTGAACGTTTTTCTCC
AGTTGGAGGTGGCATTTAGG

Downstream 100 bases:

>100_bases
GTATTGACCTGCCATCCAACGGAACCTCTCCAGGTTTGTCTACCCGCAGGTTCTGCCTCCGGTTATGATGGACTGCTGTA
GCAGGAAGAAGTAAAATCGG

Product: hydrogenase expression/formation protein HypE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MKENGRDIVLLAHGDGGALTHELINNLFLRHFESNILKTLTDAAVFSGNEGRMAITTDSFVVDPPFFPGGDVGKLAVCGT
VNDLAVSGARPIYLTASFILEEGLPLADLESIVQSMAGACGVAGVEIITGDTKVVEKGHLDKIFINTTGVGYIFPGVDLG
YHRIKPGDKVLVNGSLGQHGIAVLCKRYGFDFAGQVVSDCAPLNGITSLLLKEIRGIKIMRDLTRGGLATTAKEIASACG
LDIWLDENCIPVDAGVKGAAEMLGLDPLYLANEGKFMVIVSPEEAEKAVAVMQGHELGRDASIIGEVKPGKGNVYLSTSL
GGTKLLDLMAGSPLPRIC

Sequences:

>Translated_338_residues
MKENGRDIVLLAHGDGGALTHELINNLFLRHFESNILKTLTDAAVFSGNEGRMAITTDSFVVDPPFFPGGDVGKLAVCGT
VNDLAVSGARPIYLTASFILEEGLPLADLESIVQSMAGACGVAGVEIITGDTKVVEKGHLDKIFINTTGVGYIFPGVDLG
YHRIKPGDKVLVNGSLGQHGIAVLCKRYGFDFAGQVVSDCAPLNGITSLLLKEIRGIKIMRDLTRGGLATTAKEIASACG
LDIWLDENCIPVDAGVKGAAEMLGLDPLYLANEGKFMVIVSPEEAEKAVAVMQGHELGRDASIIGEVKPGKGNVYLSTSL
GGTKLLDLMAGSPLPRIC
>Mature_338_residues
MKENGRDIVLLAHGDGGALTHELINNLFLRHFESNILKTLTDAAVFSGNEGRMAITTDSFVVDPPFFPGGDVGKLAVCGT
VNDLAVSGARPIYLTASFILEEGLPLADLESIVQSMAGACGVAGVEIITGDTKVVEKGHLDKIFINTTGVGYIFPGVDLG
YHRIKPGDKVLVNGSLGQHGIAVLCKRYGFDFAGQVVSDCAPLNGITSLLLKEIRGIKIMRDLTRGGLATTAKEIASACG
LDIWLDENCIPVDAGVKGAAEMLGLDPLYLANEGKFMVIVSPEEAEKAVAVMQGHELGRDASIIGEVKPGKGNVYLSTSL
GGTKLLDLMAGSPLPRIC

Specific function: Unknown

COG id: COG0309

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypE family [H]

Homologues:

Organism=Escherichia coli, GI226510967, Length=335, Percent_Identity=46.865671641791, Blast_Score=293, Evalue=1e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR011854
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: NA

Molecular weight: Translated: 35520; Mature: 35520

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKENGRDIVLLAHGDGGALTHELINNLFLRHFESNILKTLTDAAVFSGNEGRMAITTDSF
CCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEEECCE
VVDPPFFPGGDVGKLAVCGTVNDLAVSGARPIYLTASFILEEGLPLADLESIVQSMAGAC
EECCCCCCCCCCCCEEEECCCHHHHHCCCCEEEEEHHHHHHCCCCHHHHHHHHHHHHCCC
GVAGVEIITGDTKVVEKGHLDKIFINTTGVGYIFPGVDLGYHRIKPGDKVLVNGSLGQHG
CCCCEEEEECCHHEECCCCCCEEEEEECCCEEEECCCCCCCEEECCCCEEEEECCCCCHH
IAVLCKRYGFDFAGQVVSDCAPLNGITSLLLKEIRGIKIMRDLTRGGLATTAKEIASACG
HHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHCHHHHHHHHCCCHHHHHHHHHHHCC
LDIWLDENCIPVDAGVKGAAEMLGLDPLYLANEGKFMVIVSPEEAEKAVAVMQGHELGRD
CEEEECCCCEEECCCCCHHHHHHCCCCEEEECCCCEEEEECCCHHHHHHHHHHCCCCCCC
ASIIGEVKPGKGNVYLSTSLGGTKLLDLMAGSPLPRIC
CEEEEEECCCCCCEEEEECCCCHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKENGRDIVLLAHGDGGALTHELINNLFLRHFESNILKTLTDAAVFSGNEGRMAITTDSF
CCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEEECCE
VVDPPFFPGGDVGKLAVCGTVNDLAVSGARPIYLTASFILEEGLPLADLESIVQSMAGAC
EECCCCCCCCCCCCEEEECCCHHHHHCCCCEEEEEHHHHHHCCCCHHHHHHHHHHHHCCC
GVAGVEIITGDTKVVEKGHLDKIFINTTGVGYIFPGVDLGYHRIKPGDKVLVNGSLGQHG
CCCCEEEEECCHHEECCCCCCEEEEEECCCEEEECCCCCCCEEECCCCEEEEECCCCCHH
IAVLCKRYGFDFAGQVVSDCAPLNGITSLLLKEIRGIKIMRDLTRGGLATTAKEIASACG
HHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHCHHHHHHHHCCCHHHHHHHHHHHCC
LDIWLDENCIPVDAGVKGAAEMLGLDPLYLANEGKFMVIVSPEEAEKAVAVMQGHELGRD
CEEEECCCCEEECCCCCHHHHHHCCCCEEEECCCCEEEEECCCHHHHHHHHHHCCCCCCC
ASIIGEVKPGKGNVYLSTSLGGTKLLDLMAGSPLPRIC
CEEEEEECCCCCCEEEEECCCCHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8510650; 7906310; 12597275 [H]