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The map label for this gene is xdhB [H]

Identifier: 83590791

GI number: 83590791

Start: 2037160

End: 2038044

Strand: Reverse

Name: xdhB [H]

Synonym: Moth_1959

Alternate gene names: 83590791

Gene position: 2038044-2037160 (Counterclockwise)

Preceding gene: 83590792

Following gene: 83590790

Centisome position: 77.53

GC content: 58.08

Gene sequence:

>885_bases
ATGTTCAACATCCAGGAATATTTTGAGGCTGCAACAGTAGAGGAAGCCACGGCGTTGCTGGCGGCCCATCCCGGCCTGAC
AGTCATCGCTGGCGGTACGGACGTTTTGATAAAAATGCATCACGGCCGGATAGCGAAGGCCGGGTTGTTGAGTATCCGGG
GTATAAAATCCCTGGAGGGTATCCTAAAGCTCGAGGATGGCACCATCGTCATCGGGGCGCTTACGACCTTTACCCGGATT
ATCAATGATCCTGTTATCCGGGCCCATATCCCCGTCCTGGCCGAAGCCGCGGCTTCCATGGGCGGTCCCCAGATTCGCAA
TGTGGCCACCATCGGCGGCAATATTTGCAATGGCGCCACCTCCGCCGACAGCGCTTCGACCCTGTTCGCCCTGAATGCCA
GGTTAAAATTACAGGACAATCAAGGGCAGAGGGTGGTCCCCATCCAGGAGTTTTACCTGGGTCCGGGCCGGGTTGATTTA
AAGCCCGGGGAGCTCCTGGCGGAGATTATTATTACGCCTGAGAATTACCGCGGCTATGGCGGCCATTATATCAAGTTTTC
CCAGCGCCGGGCCATGGATATTGCCACCCTGGGGGTGGCGGTGCTCTGTAAAATCAAAGACGGCACTACCTTTGCGGATG
TAAGGATTGGCCTGGGGGTAGCCGGGCCGACCCCCTTGAGGTGCCCCGAGGCCGAAGCCTATGCCAGCGGTCAACCAATC
TCCGCAGCCACCATCGCGGCTATCGGACGGTTGGCCGTTAAAGCGACGCAGGCCAGGACCTCCTGGCGGGCTTCGAAGGA
ATACCGGGAACACCTGGTGGCCGAGCTTACCGAGAGGGCATTAAAAGCGGCCGTCGTAAAAGCAGGGGGTAGGGAAGTTG
CTTAA

Upstream 100 bases:

>100_bases
ACGCCACGGGCGTGGCTTTTGACAGGTTGCCCATGAATCCCCAACGGGTTTTCGAAAAGTTCAAGGAAGCCGGGTTAATA
TAGTAAGGTGGTGAGGGCTG

Downstream 100 bases:

>100_bases
AAAAATCTCCTTCACGGTCAATGATACACCGGTAACTTTAGAAGTTGACGCTGGCGAGACATTGCTGGAGGTACTGCGCA
ACCGCCTGGGGTATACCGGG

Product: xanthine dehydrogenase subunit XdhB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MFNIQEYFEAATVEEATALLAAHPGLTVIAGGTDVLIKMHHGRIAKAGLLSIRGIKSLEGILKLEDGTIVIGALTTFTRI
INDPVIRAHIPVLAEAAASMGGPQIRNVATIGGNICNGATSADSASTLFALNARLKLQDNQGQRVVPIQEFYLGPGRVDL
KPGELLAEIIITPENYRGYGGHYIKFSQRRAMDIATLGVAVLCKIKDGTTFADVRIGLGVAGPTPLRCPEAEAYASGQPI
SAATIAAIGRLAVKATQARTSWRASKEYREHLVAELTERALKAAVVKAGGREVA

Sequences:

>Translated_294_residues
MFNIQEYFEAATVEEATALLAAHPGLTVIAGGTDVLIKMHHGRIAKAGLLSIRGIKSLEGILKLEDGTIVIGALTTFTRI
INDPVIRAHIPVLAEAAASMGGPQIRNVATIGGNICNGATSADSASTLFALNARLKLQDNQGQRVVPIQEFYLGPGRVDL
KPGELLAEIIITPENYRGYGGHYIKFSQRRAMDIATLGVAVLCKIKDGTTFADVRIGLGVAGPTPLRCPEAEAYASGQPI
SAATIAAIGRLAVKATQARTSWRASKEYREHLVAELTERALKAAVVKAGGREVA
>Mature_294_residues
MFNIQEYFEAATVEEATALLAAHPGLTVIAGGTDVLIKMHHGRIAKAGLLSIRGIKSLEGILKLEDGTIVIGALTTFTRI
INDPVIRAHIPVLAEAAASMGGPQIRNVATIGGNICNGATSADSASTLFALNARLKLQDNQGQRVVPIQEFYLGPGRVDL
KPGELLAEIIITPENYRGYGGHYIKFSQRRAMDIATLGVAVLCKIKDGTTFADVRIGLGVAGPTPLRCPEAEAYASGQPI
SAATIAAIGRLAVKATQARTSWRASKEYREHLVAELTERALKAAVVKAGGREVA

Specific function: Presumed to be a dehydrogenase, but possibly an oxidase. Participates in limited purine salvage (requires aspartate) but does not support aerobic growth on purines as the sole carbon source (purine catabolism) [H]

COG id: COG1319

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Escherichia coli, GI1789231, Length=291, Percent_Identity=43.9862542955326, Blast_Score=265, Evalue=2e-72,
Organism=Drosophila melanogaster, GI17737937, Length=304, Percent_Identity=25.6578947368421, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005107
- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR002346 [H]

Pfam domain/function: PF03450 CO_deh_flav_C; PF00941 FAD_binding_5 [H]

EC number: =1.17.1.4 [H]

Molecular weight: Translated: 31072; Mature: 31072

Theoretical pI: Translated: 9.35; Mature: 9.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNIQEYFEAATVEEATALLAAHPGLTVIAGGTDVLIKMHHGRIAKAGLLSIRGIKSLEG
CCCHHHHHHHHHHHHHHHHHEECCCEEEEECCCEEEEEEECCCCCHHHHHHHCCHHHHCC
ILKLEDGTIVIGALTTFTRIINDPVIRAHIPVLAEAAASMGGPQIRNVATIGGNICNGAT
EEEECCCCEEEEHHHHHHHHHCCCEEEEHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCC
SADSASTLFALNARLKLQDNQGQRVVPIQEFYLGPGRVDLKPGELLAEIIITPENYRGYG
CCCCCCEEEEEEEEEEEECCCCCEEEEHHHHCCCCCEEECCHHHEEEEEEECCCCCCCCC
GHYIKFSQRRAMDIATLGVAVLCKIKDGTTFADVRIGLGVAGPTPLRCPEAEAYASGQPI
CEEEEECCCHHHHHHHCCEEEEEEECCCCEEEEEEEEEECCCCCCCCCCCCHHHCCCCCC
SAATIAAIGRLAVKATQARTSWRASKEYREHLVAELTERALKAAVVKAGGREVA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MFNIQEYFEAATVEEATALLAAHPGLTVIAGGTDVLIKMHHGRIAKAGLLSIRGIKSLEG
CCCHHHHHHHHHHHHHHHHHEECCCEEEEECCCEEEEEEECCCCCHHHHHHHCCHHHHCC
ILKLEDGTIVIGALTTFTRIINDPVIRAHIPVLAEAAASMGGPQIRNVATIGGNICNGAT
EEEECCCCEEEEHHHHHHHHHCCCEEEEHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCC
SADSASTLFALNARLKLQDNQGQRVVPIQEFYLGPGRVDLKPGELLAEIIITPENYRGYG
CCCCCCEEEEEEEEEEEECCCCCEEEEHHHHCCCCCEEECCHHHEEEEEEECCCCCCCCC
GHYIKFSQRRAMDIATLGVAVLCKIKDGTTFADVRIGLGVAGPTPLRCPEAEAYASGQPI
CEEEEECCCHHHHHHHCCEEEEEEECCCCEEEEEEEEEECCCCCCCCCCCCHHHCCCCCC
SAATIAAIGRLAVKATQARTSWRASKEYREHLVAELTERALKAAVVKAGGREVA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]