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The map label for this gene is xdhC [H]

Identifier: 83590790

GI number: 83590790

Start: 2036706

End: 2037167

Strand: Reverse

Name: xdhC [H]

Synonym: Moth_1958

Alternate gene names: 83590790

Gene position: 2037167-2036706 (Counterclockwise)

Preceding gene: 83590791

Following gene: 83590789

Centisome position: 77.49

GC content: 52.16

Gene sequence:

>462_bases
TTGCTTAAAAAAATCTCCTTCACGGTCAATGATACACCGGTAACTTTAGAAGTTGACGCTGGCGAGACATTGCTGGAGGT
ACTGCGCAACCGCCTGGGGTATACCGGGGTGAAAAAGGGATGCGGTGTGGGCGAATGCGGCGCCTGCACCGTGCTTATCG
ACGGTACTCCGGTGGACTCCTGCATCTACCTGGCTGTTTGGGCGGAAGGGAAAAAGATAATTACCATAGAAGGCATAGCC
AAAAACGGGGAACTCTCCAGGGTACAGAAAGCCTTTATAGAAGAGGGCGCCATCCAGTGCGGCTTCTGCACGCCAGGCTA
TGTCCTTACCGCTACAGCCTTGGTAGAAAGCGGTAAAAAATATTCTCGGGAAGAAATTAAGCGGGAACTGGCCGGCCATC
TCTGCCGCTGCACCGGTTATCAGAATATCCTCAGGGCCGTGGAGAAAGCCTTAAACGATTAA

Upstream 100 bases:

>100_bases
ACCTCCTGGCGGGCTTCGAAGGAATACCGGGAACACCTGGTGGCCGAGCTTACCGAGAGGGCATTAAAAGCGGCCGTCGT
AAAAGCAGGGGGTAGGGAAG

Downstream 100 bases:

>100_bases
GTCAAAGGAGGGGGAACCTATGCTTCTCATCGGTAACGGCCGCCTACTTTCCCTGGTGCCGGGGAAACCCTACCAGGAAG
ACGGAGCGGTGGCCATTGAC

Product: (2Fe-2S)-binding

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 153; Mature: 153

Protein sequence:

>153_residues
MLKKISFTVNDTPVTLEVDAGETLLEVLRNRLGYTGVKKGCGVGECGACTVLIDGTPVDSCIYLAVWAEGKKIITIEGIA
KNGELSRVQKAFIEEGAIQCGFCTPGYVLTATALVESGKKYSREEIKRELAGHLCRCTGYQNILRAVEKALND

Sequences:

>Translated_153_residues
MLKKISFTVNDTPVTLEVDAGETLLEVLRNRLGYTGVKKGCGVGECGACTVLIDGTPVDSCIYLAVWAEGKKIITIEGIA
KNGELSRVQKAFIEEGAIQCGFCTPGYVLTATALVESGKKYSREEIKRELAGHLCRCTGYQNILRAVEKALND
>Mature_153_residues
MLKKISFTVNDTPVTLEVDAGETLLEVLRNRLGYTGVKKGCGVGECGACTVLIDGTPVDSCIYLAVWAEGKKIITIEGIA
KNGELSRVQKAFIEEGAIQCGFCTPGYVLTATALVESGKKYSREEIKRELAGHLCRCTGYQNILRAVEKALND

Specific function: Iron-sulfur subunit of the xanthine dehydrogenase complex [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=154, Percent_Identity=36.3636363636364, Blast_Score=70, Evalue=9e-13,
Organism=Escherichia coli, GI1789232, Length=145, Percent_Identity=55.1724137931034, Blast_Score=159, Evalue=8e-41,
Organism=Escherichia coli, GI1786480, Length=164, Percent_Identity=37.8048780487805, Blast_Score=122, Evalue=1e-29,
Organism=Escherichia coli, GI1789246, Length=147, Percent_Identity=31.2925170068027, Blast_Score=75, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17539860, Length=155, Percent_Identity=39.3548387096774, Blast_Score=99, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17540638, Length=141, Percent_Identity=40.4255319148936, Blast_Score=99, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI32566215, Length=158, Percent_Identity=36.7088607594937, Blast_Score=98, Evalue=2e-21,
Organism=Drosophila melanogaster, GI17737937, Length=150, Percent_Identity=37.3333333333333, Blast_Score=88, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24647197, Length=163, Percent_Identity=32.5153374233129, Blast_Score=78, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24647195, Length=163, Percent_Identity=32.5153374233129, Blast_Score=78, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24647201, Length=152, Percent_Identity=33.5526315789474, Blast_Score=77, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24647199, Length=151, Percent_Identity=32.4503311258278, Blast_Score=74, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24647193, Length=138, Percent_Identity=32.6086956521739, Blast_Score=70, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: NA

Molecular weight: Translated: 16518; Mature: 16518

Theoretical pI: Translated: 6.99; Mature: 6.99

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.2 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
5.2 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKKISFTVNDTPVTLEVDAGETLLEVLRNRLGYTGVKKGCGVGECGACTVLIDGTPVDS
CCCEEEEEECCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCC
CIYLAVWAEGKKIITIEGIAKNGELSRVQKAFIEEGAIQCGFCTPGYVLTATALVESGKK
EEEEEEEECCCEEEEEECCCCCCHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHCCCC
YSREEIKRELAGHLCRCTGYQNILRAVEKALND
CCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MLKKISFTVNDTPVTLEVDAGETLLEVLRNRLGYTGVKKGCGVGECGACTVLIDGTPVDS
CCCEEEEEECCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCC
CIYLAVWAEGKKIITIEGIAKNGELSRVQKAFIEEGAIQCGFCTPGYVLTATALVESGKK
EEEEEEEECCCEEEEEECCCCCCHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHCCCC
YSREEIKRELAGHLCRCTGYQNILRAVEKALND
CCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Iron-Sulfur [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]