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The map label for this gene is yggV [C]

Identifier: 83594969

GI number: 83594969

Start: 4181442

End: 4182047

Strand: Reverse

Name: yggV [C]

Synonym: Rru_A3640

Alternate gene names: 83594969

Gene position: 4182047-4181442 (Counterclockwise)

Preceding gene: 83594970

Following gene: 83594968

Centisome position: 96.08

GC content: 67.99

Gene sequence:

>606_bases
ATGGCCATGTCGCGTCGCCTTGTTGAAAGTCCGCTGGTCGTTGCCAGCCATAACGCCGGAAAGGTCCGCGAGATCGCCGA
GTTGATCGCGCCCTTCGGCCTGGAAGCGCGATCGGCGGCCAGCCTCGATCTGCCCGAACCCGAGGAAACCGGATCGAGCT
TCGTCGAAAACGCCCTGCTCAAGGCCCATGCGGCGGCCCGGGCCACCGGTCTGCCCGCCCTGGCCGATGATTCCGGGCTG
GCCGTCAGCGCCCTGGGCGGCGATCCCGGCATCTACTCGGCGCGATGGGCCGGTCCGACCAAGGACTTCGCCTTGGCCAT
GGCGACGATTAATCATCTCCTAGGAGACAATCCCGACCGCAGCGCCCATTTCGTCTGCGCCCTCGCCCTGGCTTGGCCCG
ATGGTCATGCCGAGACCTTCGAGGGCCGGGTCGACGGCGTGCTGGTCTGGCCACCGCGCGGCGATCAGGGCTTTGGCTAT
GATCCGATGTTCCTGGGCGAGGGCGCGGCCGAAACCTTTGGCGAGATGGACCCGGCGGCCAAACACGCCATCAGCCACCG
CGCCCGCGCCTTCGCCTTGCTGGTGGCGGCATGCCTGGGCGGCTGA

Upstream 100 bases:

>100_bases
GGCCCTGGCGCAAAAAGGCATCACCGAGTTGGTCGCCCTGCAGAAGGCGGCCCTCGCCAGCTTGCGCTAATTCTTTTCCG
TTTCCCCCGATCAGGACCTG

Downstream 100 bases:

>100_bases
GCCCCCCTGCCACCGCCGTCGCCACCGCCGTCGGGGCCCAGGGGGACGAGGGCTTCGGCGTTTATGTCCATTGGCCGTTC
TGCCTGTCGAAATGCCCCTA

Product: putative deoxyribonucleotide triphosphate pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase

Number of amino acids: Translated: 201; Mature: 200

Protein sequence:

>201_residues
MAMSRRLVESPLVVASHNAGKVREIAELIAPFGLEARSAASLDLPEPEETGSSFVENALLKAHAAARATGLPALADDSGL
AVSALGGDPGIYSARWAGPTKDFALAMATINHLLGDNPDRSAHFVCALALAWPDGHAETFEGRVDGVLVWPPRGDQGFGY
DPMFLGEGAAETFGEMDPAAKHAISHRARAFALLVAACLGG

Sequences:

>Translated_201_residues
MAMSRRLVESPLVVASHNAGKVREIAELIAPFGLEARSAASLDLPEPEETGSSFVENALLKAHAAARATGLPALADDSGL
AVSALGGDPGIYSARWAGPTKDFALAMATINHLLGDNPDRSAHFVCALALAWPDGHAETFEGRVDGVLVWPPRGDQGFGY
DPMFLGEGAAETFGEMDPAAKHAISHRARAFALLVAACLGG
>Mature_200_residues
AMSRRLVESPLVVASHNAGKVREIAELIAPFGLEARSAASLDLPEPEETGSSFVENALLKAHAAARATGLPALADDSGLA
VSALGGDPGIYSARWAGPTKDFALAMATINHLLGDNPDRSAHFVCALALAWPDGHAETFEGRVDGVLVWPPRGDQGFGYD
PMFLGEGAAETFGEMDPAAKHAISHRARAFALLVAACLGG

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family

Homologues:

Organism=Homo sapiens, GI15626999, Length=191, Percent_Identity=34.0314136125654, Blast_Score=94, Evalue=6e-20,
Organism=Homo sapiens, GI31657144, Length=155, Percent_Identity=36.7741935483871, Blast_Score=85, Evalue=4e-17,
Organism=Escherichia coli, GI1789324, Length=197, Percent_Identity=43.6548223350254, Blast_Score=142, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17556833, Length=178, Percent_Identity=33.7078651685393, Blast_Score=84, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6322529, Length=193, Percent_Identity=27.4611398963731, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI19920712, Length=186, Percent_Identity=32.258064516129, Blast_Score=87, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NTPA_RHORT (Q2RN61)

Other databases:

- EMBL:   CP000230
- RefSeq:   YP_428721.1
- ProteinModelPortal:   Q2RN61
- SMR:   Q2RN61
- STRING:   Q2RN61
- GeneID:   3837096
- GenomeReviews:   CP000230_GR
- KEGG:   rru:Rru_A3640
- NMPDR:   fig|1085.1.peg.1276
- eggNOG:   COG0127
- HOGENOM:   HBG697237
- OMA:   VYTADWA
- PhylomeDB:   Q2RN61
- ProtClustDB:   PRK00120
- BioCyc:   RRUB269796:RRU_A3640-MONOMER
- HAMAP:   MF_01405
- InterPro:   IPR002637
- InterPro:   IPR020922
- PANTHER:   PTHR11067
- TIGRFAMs:   TIGR00042

Pfam domain/function: PF01725 Ham1p_like

EC number: =3.6.1.15

Molecular weight: Translated: 20884; Mature: 20753

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAMSRRLVESPLVVASHNAGKVREIAELIAPFGLEARSAASLDLPEPEETGSSFVENALL
CCCCHHHHHCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
KAHAAARATGLPALADDSGLAVSALGGDPGIYSARWAGPTKDFALAMATINHLLGDNPDR
HHHHHHHHCCCCCEECCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCC
SAHFVCALALAWPDGHAETFEGRVDGVLVWPPRGDQGFGYDPMFLGEGAAETFGEMDPAA
CCEEEEEEEEECCCCCCCCCCCCCCEEEEECCCCCCCCCCCCEEECCCHHHHHHCCCHHH
KHAISHRARAFALLVAACLGG
HHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AMSRRLVESPLVVASHNAGKVREIAELIAPFGLEARSAASLDLPEPEETGSSFVENALL
CCCHHHHHCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
KAHAAARATGLPALADDSGLAVSALGGDPGIYSARWAGPTKDFALAMATINHLLGDNPDR
HHHHHHHHCCCCCEECCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCC
SAHFVCALALAWPDGHAETFEGRVDGVLVWPPRGDQGFGYDPMFLGEGAAETFGEMDPAA
CCEEEEEEEEECCCCCCCCCCCCCCEEEEECCCCCCCCCCCCEEECCCHHHHHHCCCHHH
KHAISHRARAFALLVAACLGG
HHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA