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The map label for this gene is plsC [H]

Identifier: 83594587

GI number: 83594587

Start: 3752851

End: 3753618

Strand: Direct

Name: plsC [H]

Synonym: Rru_A3257

Alternate gene names: 83594587

Gene position: 3752851-3753618 (Clockwise)

Preceding gene: 83594586

Following gene: 83594588

Centisome position: 86.22

GC content: 65.89

Gene sequence:

>768_bases
ATGATGGCCCTAGCGCGCTCCGTTCTTTTCAATATTTTCTATCTCGGCTGGACGATCACCATGGGCGTCCTGTTCGTCCC
CGTCCTGGCCTTTCGCGCCCATGCCGTGCGCGCCGTCGCCCGCTTCTGGCTCAAGGGCTTCGTTCTTGGCGCCCGCGTGC
TGCTGGGGCTCAAGCTCGAGATTCGCGGCCGCGAGAACCTGCCGACCGGTCCGGCCATCATCGCCTCCAAGCACCAAAGC
GCCTTCGAGACCTTCGTCTTCCATCAGCTGGTCGAGGATCCGATCTATGTTCTGAAAAAAGAACTGGTCACCATCCCCTT
CGTCGGCTGGTACATGGCGCGCTCGGGGCAGGTCTCGGTCGACCGCAAGGCCGGCGCCGGGGCGATGAAGGCGATGATCC
GCGATGTCCGCACCGCCCTGAACAAAGGGGGAACGATCATCATCTTCCCCGAAGGCACCCGCACCCTGCCCGGCGACTGC
CCGCCCTATCAGCCCGGCGTGGCCGCCCTTTACACCCAGATGGGCGTTCCCGTGGTCCCCGTCGCCCTCAACTCCGGGCT
GTTCTGGTCGCGCAACAGCTTCATGAAGCGCTCAGGCACGGTGGTTCTTGAAATTCTGCCGCCGATCCCGCCCGGTCTTG
ACCGCAAGGTCTTCATGACCCAGCTACGCGAGCGCATCGAAACCGCCAGCGCCGCCCTGGCCGGTTTGCCGGCGCCGTCG
CTGACCCTGGCGGCCCCGGCGGACCCGGCCCCGTCCCTGGGCGCCTGA

Upstream 100 bases:

>100_bases
TGTCGCCGGTCAATGTCGAGGCTTTGGCCGCGCCGCTGTTTCCGCCCCCGGTCGGGCCGTCGTCTTCCACCCCCTCCCCC
TCCTCCACCGGCGAGACCCG

Downstream 100 bases:

>100_bases
TCCCTTTTCAGACCCTTTCCTTTTCGCGTTTTTCCCCCACCAAGGAGTTTCCCCCATGGACCGCCAGCCTATCGTCGAAA
GCATCTGGCGGGAGAAGTAC

Product: 1-acyl-sn-glycerol-3-phosphate acyltransferase

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT [H]

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MMALARSVLFNIFYLGWTITMGVLFVPVLAFRAHAVRAVARFWLKGFVLGARVLLGLKLEIRGRENLPTGPAIIASKHQS
AFETFVFHQLVEDPIYVLKKELVTIPFVGWYMARSGQVSVDRKAGAGAMKAMIRDVRTALNKGGTIIIFPEGTRTLPGDC
PPYQPGVAALYTQMGVPVVPVALNSGLFWSRNSFMKRSGTVVLEILPPIPPGLDRKVFMTQLRERIETASAALAGLPAPS
LTLAAPADPAPSLGA

Sequences:

>Translated_255_residues
MMALARSVLFNIFYLGWTITMGVLFVPVLAFRAHAVRAVARFWLKGFVLGARVLLGLKLEIRGRENLPTGPAIIASKHQS
AFETFVFHQLVEDPIYVLKKELVTIPFVGWYMARSGQVSVDRKAGAGAMKAMIRDVRTALNKGGTIIIFPEGTRTLPGDC
PPYQPGVAALYTQMGVPVVPVALNSGLFWSRNSFMKRSGTVVLEILPPIPPGLDRKVFMTQLRERIETASAALAGLPAPS
LTLAAPADPAPSLGA
>Mature_255_residues
MMALARSVLFNIFYLGWTITMGVLFVPVLAFRAHAVRAVARFWLKGFVLGARVLLGLKLEIRGRENLPTGPAIIASKHQS
AFETFVFHQLVEDPIYVLKKELVTIPFVGWYMARSGQVSVDRKAGAGAMKAMIRDVRTALNKGGTIIIFPEGTRTLPGDC
PPYQPGVAALYTQMGVPVVPVALNSGLFWSRNSFMKRSGTVVLEILPPIPPGLDRKVFMTQLRERIETASAALAGLPAPS
LTLAAPADPAPSLGA

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI5453718, Length=201, Percent_Identity=29.3532338308458, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI15100175, Length=201, Percent_Identity=29.3532338308458, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI6041665, Length=181, Percent_Identity=30.3867403314917, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI1789395, Length=160, Percent_Identity=30.625, Blast_Score=67, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320151, Length=162, Percent_Identity=30.2469135802469, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24641614, Length=228, Percent_Identity=28.0701754385965, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24641612, Length=228, Percent_Identity=28.0701754385965, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI281364648, Length=160, Percent_Identity=27.5, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24582856, Length=160, Percent_Identity=27.5, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24582854, Length=160, Percent_Identity=27.5, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 27596; Mature: 27596

Theoretical pI: Translated: 10.86; Mature: 10.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMALARSVLFNIFYLGWTITMGVLFVPVLAFRAHAVRAVARFWLKGFVLGARVLLGLKLE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEE
IRGRENLPTGPAIIASKHQSAFETFVFHQLVEDPIYVLKKELVTIPFVGWYMARSGQVSV
ECCCCCCCCCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCEEE
DRKAGAGAMKAMIRDVRTALNKGGTIIIFPEGTRTLPGDCPPYQPGVAALYTQMGVPVVP
CCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHCCCCEEE
VALNSGLFWSRNSFMKRSGTVVLEILPPIPPGLDRKVFMTQLRERIETASAALAGLPAPS
EEECCCEEECCCHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
LTLAAPADPAPSLGA
EEEECCCCCCCCCCC
>Mature Secondary Structure
MMALARSVLFNIFYLGWTITMGVLFVPVLAFRAHAVRAVARFWLKGFVLGARVLLGLKLE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEE
IRGRENLPTGPAIIASKHQSAFETFVFHQLVEDPIYVLKKELVTIPFVGWYMARSGQVSV
ECCCCCCCCCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCEEE
DRKAGAGAMKAMIRDVRTALNKGGTIIIFPEGTRTLPGDCPPYQPGVAALYTQMGVPVVP
CCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHCCCCEEE
VALNSGLFWSRNSFMKRSGTVVLEILPPIPPGLDRKVFMTQLRERIETASAALAGLPAPS
EEECCCEEECCCHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
LTLAAPADPAPSLGA
EEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9403685; 7812434 [H]