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The map label for this gene is copR [H]

Identifier: 83594245

GI number: 83594245

Start: 3356164

End: 3356847

Strand: Direct

Name: copR [H]

Synonym: Rru_A2913

Alternate gene names: 83594245

Gene position: 3356164-3356847 (Clockwise)

Preceding gene: 83594244

Following gene: 83594246

Centisome position: 77.1

GC content: 66.08

Gene sequence:

>684_bases
ATGCGCATCCTGGTGATCGAGGATGACAAGGAGGTGGCCGCCCACCTTCTCAAAGGCCTGCGCGAGGCCGGCCATGTCGC
CGACAGCGTGGCCGATGGCCGCGACGGCCTGTTCCAGGCCGCCGGGGAAGCCTATGACCTGCTGATCGTCGATCGCATGC
TGCCCAATGTCGACGGTCTGACCATCGTCCGCACCCTGCGGGCTTCGGGCAAAACGGTGCCGGTGCTGATCCTCTCGGCG
CTCGGCGAGGTCGACGACCGGGTCAAGGGGCTGCGGGCGGGGGGCGATGACTATCTGGTCAAGCCCTTCGCCTTCGCCGA
GCTTCTGGCCCGCATCGACGCCCTGACCCGGCGCACGGCGGGAAGCGACGCCGAACAGACGCGGTTGCGGGCGGGCGAGG
TGGAGATGGACCTGCTGGCCCGCCGGGTCACCCGTGGCTCGCGCACCATCGATCTTCAGCCCCGCGAATTCCGCCTGCTT
GAATACCTGATGCGCCATGCCGATCAGGTGGTCACCCGCACCATGCTTTTGGAAAACGTCTGGGATTATCACTTCGACCC
GCAGACCAACGTCGTTGACGTTCATATCAGCCGCCTGCGCCGCAAGATGGACGAGGGCTTCGCCCAGCCCTTCCTGGAAA
CCGTGCGGGGGGCGGGCTACGTCTTGCGCACCAATGGCTCTTAA

Upstream 100 bases:

>100_bases
CACCCTGCCTGACGCCGACGACGACACCCCCGACGCGTCCCCGCGTTGATCTAAGACCCAACGCGTCCTCGCGTTGATAA
CGGAAAGGGAGGGCGGCCCG

Downstream 100 bases:

>100_bases
GCTTCCCCGCCGGCTGCTGCCGCGCAGCACCACCTTACGCATCGCGCTTAGTTTCCTCGTGTTGTTTGGCGGAGCCTCGG
GCCTGCTGATGGCCGGGGTC

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MRILVIEDDKEVAAHLLKGLREAGHVADSVADGRDGLFQAAGEAYDLLIVDRMLPNVDGLTIVRTLRASGKTVPVLILSA
LGEVDDRVKGLRAGGDDYLVKPFAFAELLARIDALTRRTAGSDAEQTRLRAGEVEMDLLARRVTRGSRTIDLQPREFRLL
EYLMRHADQVVTRTMLLENVWDYHFDPQTNVVDVHISRLRRKMDEGFAQPFLETVRGAGYVLRTNGS

Sequences:

>Translated_227_residues
MRILVIEDDKEVAAHLLKGLREAGHVADSVADGRDGLFQAAGEAYDLLIVDRMLPNVDGLTIVRTLRASGKTVPVLILSA
LGEVDDRVKGLRAGGDDYLVKPFAFAELLARIDALTRRTAGSDAEQTRLRAGEVEMDLLARRVTRGSRTIDLQPREFRLL
EYLMRHADQVVTRTMLLENVWDYHFDPQTNVVDVHISRLRRKMDEGFAQPFLETVRGAGYVLRTNGS
>Mature_227_residues
MRILVIEDDKEVAAHLLKGLREAGHVADSVADGRDGLFQAAGEAYDLLIVDRMLPNVDGLTIVRTLRASGKTVPVLILSA
LGEVDDRVKGLRAGGDDYLVKPFAFAELLARIDALTRRTAGSDAEQTRLRAGEVEMDLLARRVTRGSRTIDLQPREFRLL
EYLMRHADQVVTRTMLLENVWDYHFDPQTNVVDVHISRLRRKMDEGFAQPFLETVRGAGYVLRTNGS

Specific function: Member of the two-component regulatory system CopS/CopR. Involved in the activation of copper resistance gene operon CopABCD. Phosphorylation of CopR by CopS would convert it into an active state to induce expression of the cop operon by binding to a spec

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786784, Length=222, Percent_Identity=47.2972972972973, Blast_Score=211, Evalue=3e-56,
Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=44.5454545454545, Blast_Score=187, Evalue=5e-49,
Organism=Escherichia coli, GI1789402, Length=222, Percent_Identity=41.4414414414414, Blast_Score=158, Evalue=3e-40,
Organism=Escherichia coli, GI1786599, Length=225, Percent_Identity=35.5555555555556, Blast_Score=141, Evalue=4e-35,
Organism=Escherichia coli, GI1790552, Length=225, Percent_Identity=36.8888888888889, Blast_Score=138, Evalue=2e-34,
Organism=Escherichia coli, GI1789809, Length=232, Percent_Identity=35.7758620689655, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1787375, Length=222, Percent_Identity=33.3333333333333, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1786911, Length=219, Percent_Identity=35.1598173515982, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1788394, Length=220, Percent_Identity=32.2727272727273, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1790860, Length=224, Percent_Identity=32.1428571428571, Blast_Score=110, Evalue=7e-26,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=36.4035087719298, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI145693140, Length=231, Percent_Identity=31.1688311688312, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=30.5676855895196, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1787229, Length=226, Percent_Identity=26.5486725663717, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1790437, Length=134, Percent_Identity=31.3432835820896, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=30.8411214953271, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1788713, Length=115, Percent_Identity=31.304347826087, Blast_Score=61, Evalue=6e-11,
Organism=Escherichia coli, GI1790299, Length=111, Percent_Identity=28.8288288288288, Blast_Score=60, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR006291
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25381; Mature: 25381

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILVIEDDKEVAAHLLKGLREAGHVADSVADGRDGLFQAAGEAYDLLIVDRMLPNVDGL
CEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHCCCCCCH
TIVRTLRASGKTVPVLILSALGEVDDRVKGLRAGGDDYLVKPFAFAELLARIDALTRRTA
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEECHHHHHHHHHHHHHHHHHCC
GSDAEQTRLRAGEVEMDLLARRVTRGSRTIDLQPREFRLLEYLMRHADQVVTRTMLLENV
CCCHHHHHHHCCCHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
WDYHFDPQTNVVDVHISRLRRKMDEGFAQPFLETVRGAGYVLRTNGS
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
>Mature Secondary Structure
MRILVIEDDKEVAAHLLKGLREAGHVADSVADGRDGLFQAAGEAYDLLIVDRMLPNVDGL
CEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHCCCCCCH
TIVRTLRASGKTVPVLILSALGEVDDRVKGLRAGGDDYLVKPFAFAELLARIDALTRRTA
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEECHHHHHHHHHHHHHHHHHCC
GSDAEQTRLRAGEVEMDLLARRVTRGSRTIDLQPREFRLLEYLMRHADQVVTRTMLLENV
CCCHHHHHHHCCCHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
WDYHFDPQTNVVDVHISRLRRKMDEGFAQPFLETVRGAGYVLRTNGS
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8449873; 8078459 [H]