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The map label for this gene is baeS [H]

Identifier: 83594246

GI number: 83594246

Start: 3356837

End: 3358438

Strand: Direct

Name: baeS [H]

Synonym: Rru_A2914

Alternate gene names: 83594246

Gene position: 3356837-3358438 (Clockwise)

Preceding gene: 83594245

Following gene: 83594247

Centisome position: 77.12

GC content: 70.16

Gene sequence:

>1602_bases
ATGGCTCTTAAGCTTCCCCGCCGGCTGCTGCCGCGCAGCACCACCTTACGCATCGCGCTTAGTTTCCTCGTGTTGTTTGG
CGGAGCCTCGGGCCTGCTGATGGCCGGGGTCTATTGGACGACCTCGCGCTTCCTGATGTTTCAGGTCGATGGGGTGATCG
GCGACGATATCGCCCTGCTGACCAATGCCGCCCGCGAACGTGGCCACCGCTTGCTGGCCGCCATGCTGGTCACCCGCGCC
CGTCAGGCCGGCGAGGCCCAGGCGGTTTACCTGCTTGCCGATCAGGACGGCGAACCGCTGGCGGGCAATCTGGCCACTTG
GCCCGAGGGGCTAGAGGCGACCGGCTGGACCATCCTGCCCGCCACCGCGCTCACCGTCGTTCCCGTCACCGATACCCTGC
CGCCGCCGCCAAGGCGCCCCGACCGCCCCGAGGACTCCGAGCGCCGCCAGCGTCACCGCGAGGCCTGGGACGATTGGCGC
CCGCCCTTGCCCGACAGCCTGCCGCCCCCCCCGCCCCGCCTGTTCGCCGATCGCGGCGGCCGTGATCCCGCCGATCCCGA
TGTCCGGCCGCGACCCTGGCGGCGGGGCGATGTGCGGGTGGCCGCCCTGACCCTGCCCAGCGGCATGCGCCTGTTGATTG
GCCGCGATCTTGGGCCGATCCAGGCCCTGCGCCACCGCATGGCCGGGGCCATGCGCCTGGGGCTGGGCGGCATGGTGGTG
CTGGGTCTGGCCGGCGGTCTGGTGATGAGCCGGCGCTTCAGCCGACGGCTGGAGGCGGTCAACCGCACCAGCCGCGAGAT
CATCGGCGGCGATCTGTCGCGGCGGGTTCCGCAAGGCCGGGGCCTGGACGGCGACGACTTCGACCAATTGGCGGTCAATC
TCAACGCCATGCTCGGGCGCATCGAAACCCTGATGGAGGGGGTGCGCCATGTCTCCGACACCATCGCCCATGATCTGCGT
ACCCCGCTGTCGCGGCTGCGCAACCGGCTGGAGCGCCTGCAGGCCGATGCCCAATGCACCGACCGCGACGAATTGGCCGC
CGCCCTGGCCGAGGTCGATAGCCTGCTCGCCACCTTCCACGCCCTGTTGCGCATCGCCCAGGTGGAAACAGGCGGCCGGC
GCATGGCCTTTTCGCCCGTCGATCTGCTGGCCCTGCTCATCGATGTCGCCGAACTTTACGACGCGGTGGCCGACGAAAGA
ACCGTAACCCTTGATCTCGACCTCGCCTTGGCGCCGGGCGCGCGTTTGCTGGTCGATGGCGACCGCGACCTGCTGTTCCA
GGCCTTCGCCAATCTGCTCGACAACGCCGTCAAATACTCACCCGAGGGCGGCCGGGTCAGCCTCGCCCTGATCCGCGGCG
AGACCCGGGTGACGATCAGCCTGCGCGATCAGGGACCAGGGATCCCCGCAGCCGACCGCCAGCGCGTTTTCGAACGCTTC
GCCCGCCTTGATACCGCCCGCACCACCCCGGGCAACGGCCTGGGTCTGACCATGGTCGGCGCGGTGATCGAAGCCCATGA
CGGCACCATCGCCCTGGAAGACGCGCCGGGCGGCGGATTGCTGGTCCGCGTCGTCTTGCCGCTGCGCCGGGGTCCGGGCT
GA

Upstream 100 bases:

>100_bases
GTTGACGTTCATATCAGCCGCCTGCGCCGCAAGATGGACGAGGGCTTCGCCCAGCCCTTCCTGGAAACCGTGCGGGGGGC
GGGCTACGTCTTGCGCACCA

Downstream 100 bases:

>100_bases
TCCGGACGGCCCCCTCCCCCTGGCGCGACCGGTCGCGCCGCTCCATAATGGGACGCCCCGCCGTTCGCCCGCTGTTGTAA
GGAAGATCGATCATGACCCG

Product: periplasmic sensor Signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 533; Mature: 532

Protein sequence:

>533_residues
MALKLPRRLLPRSTTLRIALSFLVLFGGASGLLMAGVYWTTSRFLMFQVDGVIGDDIALLTNAARERGHRLLAAMLVTRA
RQAGEAQAVYLLADQDGEPLAGNLATWPEGLEATGWTILPATALTVVPVTDTLPPPPRRPDRPEDSERRQRHREAWDDWR
PPLPDSLPPPPPRLFADRGGRDPADPDVRPRPWRRGDVRVAALTLPSGMRLLIGRDLGPIQALRHRMAGAMRLGLGGMVV
LGLAGGLVMSRRFSRRLEAVNRTSREIIGGDLSRRVPQGRGLDGDDFDQLAVNLNAMLGRIETLMEGVRHVSDTIAHDLR
TPLSRLRNRLERLQADAQCTDRDELAAALAEVDSLLATFHALLRIAQVETGGRRMAFSPVDLLALLIDVAELYDAVADER
TVTLDLDLALAPGARLLVDGDRDLLFQAFANLLDNAVKYSPEGGRVSLALIRGETRVTISLRDQGPGIPAADRQRVFERF
ARLDTARTTPGNGLGLTMVGAVIEAHDGTIALEDAPGGGLLVRVVLPLRRGPG

Sequences:

>Translated_533_residues
MALKLPRRLLPRSTTLRIALSFLVLFGGASGLLMAGVYWTTSRFLMFQVDGVIGDDIALLTNAARERGHRLLAAMLVTRA
RQAGEAQAVYLLADQDGEPLAGNLATWPEGLEATGWTILPATALTVVPVTDTLPPPPRRPDRPEDSERRQRHREAWDDWR
PPLPDSLPPPPPRLFADRGGRDPADPDVRPRPWRRGDVRVAALTLPSGMRLLIGRDLGPIQALRHRMAGAMRLGLGGMVV
LGLAGGLVMSRRFSRRLEAVNRTSREIIGGDLSRRVPQGRGLDGDDFDQLAVNLNAMLGRIETLMEGVRHVSDTIAHDLR
TPLSRLRNRLERLQADAQCTDRDELAAALAEVDSLLATFHALLRIAQVETGGRRMAFSPVDLLALLIDVAELYDAVADER
TVTLDLDLALAPGARLLVDGDRDLLFQAFANLLDNAVKYSPEGGRVSLALIRGETRVTISLRDQGPGIPAADRQRVFERF
ARLDTARTTPGNGLGLTMVGAVIEAHDGTIALEDAPGGGLLVRVVLPLRRGPG
>Mature_532_residues
ALKLPRRLLPRSTTLRIALSFLVLFGGASGLLMAGVYWTTSRFLMFQVDGVIGDDIALLTNAARERGHRLLAAMLVTRAR
QAGEAQAVYLLADQDGEPLAGNLATWPEGLEATGWTILPATALTVVPVTDTLPPPPRRPDRPEDSERRQRHREAWDDWRP
PLPDSLPPPPPRLFADRGGRDPADPDVRPRPWRRGDVRVAALTLPSGMRLLIGRDLGPIQALRHRMAGAMRLGLGGMVVL
GLAGGLVMSRRFSRRLEAVNRTSREIIGGDLSRRVPQGRGLDGDDFDQLAVNLNAMLGRIETLMEGVRHVSDTIAHDLRT
PLSRLRNRLERLQADAQCTDRDELAAALAEVDSLLATFHALLRIAQVETGGRRMAFSPVDLLALLIDVAELYDAVADERT
VTLDLDLALAPGARLLVDGDRDLLFQAFANLLDNAVKYSPEGGRVSLALIRGETRVTISLRDQGPGIPAADRQRVFERFA
RLDTARTTPGNGLGLTMVGAVIEAHDGTIALEDAPGGGLLVRVVLPLRRGPG

Specific function: Member of the two-component regulatory system BaeS/BaeR. May activate BaeR by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=269, Percent_Identity=31.2267657992565, Blast_Score=125, Evalue=6e-30,
Organism=Escherichia coli, GI1787894, Length=271, Percent_Identity=32.1033210332103, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI1786783, Length=275, Percent_Identity=29.0909090909091, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1788713, Length=222, Percent_Identity=25.2252252252252, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1790346, Length=255, Percent_Identity=29.0196078431373, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI1786600, Length=231, Percent_Identity=29.004329004329, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1789808, Length=246, Percent_Identity=29.2682926829268, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1790861, Length=252, Percent_Identity=30.1587301587302, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI1786912, Length=256, Percent_Identity=28.125, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1788279, Length=242, Percent_Identity=25.2066115702479, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1790551, Length=225, Percent_Identity=29.7777777777778, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI145693157, Length=221, Percent_Identity=30.316742081448, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1788549, Length=219, Percent_Identity=27.3972602739726, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1787374, Length=241, Percent_Identity=25.7261410788382, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1789149, Length=215, Percent_Identity=28.8372093023256, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1790436, Length=222, Percent_Identity=27.027027027027, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1789403, Length=245, Percent_Identity=29.7959183673469, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI87082128, Length=227, Percent_Identity=28.6343612334802, Blast_Score=62, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 57986; Mature: 57855

Theoretical pI: Translated: 9.12; Mature: 9.12

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALKLPRRLLPRSTTLRIALSFLVLFGGASGLLMAGVYWTTSRFLMFQVDGVIGDDIALL
CCCCCCHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCEEEEEEECCCCCCHHHHH
TNAARERGHRLLAAMLVTRARQAGEAQAVYLLADQDGEPLAGNLATWPEGLEATGWTILP
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEC
ATALTVVPVTDTLPPPPRRPDRPEDSERRQRHREAWDDWRPPLPDSLPPPPPRLFADRGG
CCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCC
RDPADPDVRPRPWRRGDVRVAALTLPSGMRLLIGRDLGPIQALRHRMAGAMRLGLGGMVV
CCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCHHHH
LGLAGGLVMSRRFSRRLEAVNRTSREIIGGDLSRRVPQGRGLDGDDFDQLAVNLNAMLGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
IETLMEGVRHVSDTIAHDLRTPLSRLRNRLERLQADAQCTDRDELAAALAEVDSLLATFH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
ALLRIAQVETGGRRMAFSPVDLLALLIDVAELYDAVADERTVTLDLDLALAPGARLLVDG
HHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCEEEEEC
DRDLLFQAFANLLDNAVKYSPEGGRVSLALIRGETRVTISLRDQGPGIPAADRQRVFERF
CHHHHHHHHHHHHHHHHEECCCCCEEEEEEEECCEEEEEEEECCCCCCCCHHHHHHHHHH
ARLDTARTTPGNGLGLTMVGAVIEAHDGTIALEDAPGGGLLVRVVLPLRRGPG
HHHHCCCCCCCCCCHHHHHHHHHEECCCEEEEECCCCCCEEEEEEHHHCCCCC
>Mature Secondary Structure 
ALKLPRRLLPRSTTLRIALSFLVLFGGASGLLMAGVYWTTSRFLMFQVDGVIGDDIALL
CCCCCHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCEEEEEEECCCCCCHHHHH
TNAARERGHRLLAAMLVTRARQAGEAQAVYLLADQDGEPLAGNLATWPEGLEATGWTILP
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEC
ATALTVVPVTDTLPPPPRRPDRPEDSERRQRHREAWDDWRPPLPDSLPPPPPRLFADRGG
CCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCC
RDPADPDVRPRPWRRGDVRVAALTLPSGMRLLIGRDLGPIQALRHRMAGAMRLGLGGMVV
CCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCHHHH
LGLAGGLVMSRRFSRRLEAVNRTSREIIGGDLSRRVPQGRGLDGDDFDQLAVNLNAMLGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
IETLMEGVRHVSDTIAHDLRTPLSRLRNRLERLQADAQCTDRDELAAALAEVDSLLATFH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
ALLRIAQVETGGRRMAFSPVDLLALLIDVAELYDAVADERTVTLDLDLALAPGARLLVDG
HHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCEEEEEC
DRDLLFQAFANLLDNAVKYSPEGGRVSLALIRGETRVTISLRDQGPGIPAADRQRVFERF
CHHHHHHHHHHHHHHHHEECCCCCEEEEEEEECCEEEEEEEECCCCCCCCHHHHHHHHHH
ARLDTARTTPGNGLGLTMVGAVIEAHDGTIALEDAPGGGLLVRVVLPLRRGPG
HHHHCCCCCCCCCCHHHHHHHHHEECCCEEEEECCCCCCEEEEEEHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8282725; 9097040; 9278503 [H]