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The map label for this gene is gmr [H]

Identifier: 83594200

GI number: 83594200

Start: 3302940

End: 3304607

Strand: Direct

Name: gmr [H]

Synonym: Rru_A2868

Alternate gene names: 83594200

Gene position: 3302940-3304607 (Clockwise)

Preceding gene: 83594199

Following gene: 83594201

Centisome position: 75.88

GC content: 65.23

Gene sequence:

>1668_bases
ATGGCTTTCGGCTCATGGAGCTTACGCGCCCAGGTCGGGTTGGTTTTCGGCTCGTTGGTTACCCTTGTCTGCACCGTTCT
CGTCTGGACCTCCAACACCGTCCTTGAAGCCAAGGGCGAAGAGGCCATCGGGGTTCAGTTATCGTCCATTGCGTCGAACA
TGGCCGATAAGTTCGACCGCGGCATGATGTCGCGGATTTCCGAAATCGCTTTCGTCTCTAGCCTCGACTTGTTCCGCAAT
CCCTCGAATCCGCGCGCCATCCGCCATACCCTCGACGATTTGCAAGAGGCCGTGCCCTATTTCACCTGGATCGGCTTCAC
CGATCCGACGGGAACCGTCAGGGCCGGCACCAATGGCCTGCTCGAGGGCGCCGACTTCAGCCAACGCGCGGTGTTTCAGC
AAGGCATCCAGGGTCCCTTCACCGGCAACCTCCACGAGGCGCCGATGCTCGCCAAGGCTTTGGGGGCGTCGGGCGCCGAA
CCCATGCGCTTTCTCGACATCACCTTTCCCGTGACCGATCTCGCCGGCGCGGTGGTCGGCATGCTGAGCGCCCATATCGA
CTGGGCCTGGGCCCGCGAACTCGAACACGCGGCCCTTGAAAGCGCCCTCAGTCGCCAGGGGTTGGAGCTCTTGGTCGTTG
ATCATGCGGGAACGGTGTTGCTGCGTCCCGAAGGCCTCGCCCTACCCAAGACGCTCGACCTCGAGGCCCTGCGCCACTCC
CAAACCCGCCCCAAGGGTTGGACCATCGAGACGTGGCCCGACGGCAAGGTTTATCTGACCGGCTATGCCCGCCAGAGGGG
CTACAAGGCCTTTGCCGGATTTGGCTGGCGAATCCTCGCCCGTCAGCCCGTCGAGATCGCTTTCGCTCCCTTGGCCGAGG
TGCGCCACACCCTGCTGCTGGCCGGGGTGGTGGGCGGGGTAATCTTCGGGGCGATCGCCTGGATCACCGCCGGCGCCATC
GCCCGGCCGCTCAAACGGATCACCGAGGCCGCCGACGGCCTGCGCGACGGCGCGGTGGGCGCGGCCCTGCCCCATCTGAC
CGGCAGCAAGGAGATCGAACGGCTTTCCGAATCCCTGCGCCTGCTGATCAATGCCCTGACCGCCACCGACCGCCGCATGG
GGCGGATGGAAAAGCTCGCCCATAACGACCTGTTGACCGGCCTGCCCAATCGCGCCGCCCTTGGCGCCTATCTCGACCGC
GTCGTTCCCGCCCTCAGCAACGCCCAGGCCGCCATCGCCTTCCTGTATCTTGATCTCGACGGCTTCAAGGCGGTCAACGA
CACCCTCGGCCACGGGGCGGGCGACGACCTGCTCAAGGCCGCCGCCGGCCGCATCCTCGACTGCCTGCGCCAAGGCGACA
TGGCGATACGCCTGGGGGGCGATGAATTCGTCGTCATCGTCAACACCTCGGCCTCAAGCTGGCGCCAGGAATCGATCCGG
GTCGCCGAAAGGCTCCTTACCGCCCTCGATGGTCCCTTCGCCTTGCCCGGCGGCGTCCGGGCGAAAATCGGCTGCAGCAT
CGGCATCGCCGCCTGGCCCGACGATCATTGCGACATCGAAGGCGCCCTTCACCACGCCGATATCGCCCTGTATCAGGCCA
AACGCCTGGGAAAGGGCCAATCGGTGGTCTATGCCGACCTGCCGAAATCGGTCCTTCACGACGGATAA

Upstream 100 bases:

>100_bases
CCGCTAAATAGGCATAGACCATCTGATATGTTAAAGCTATCTTCTCCGAGATGGGTTTCACGGGCAACGCCCGCCGAAAA
ACACTCTTGGAAGGCGGCTG

Downstream 100 bases:

>100_bases
GGGCCGATGCGGGCGCCTTCTCGCCGTCCGGGCGTTTGTAGCGATTGCTCCGATGGTCACATATGCTTATCTTGCCCGTC
ATTCGCCGCCACGTTAGACC

Product: diguanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 555; Mature: 554

Protein sequence:

>555_residues
MAFGSWSLRAQVGLVFGSLVTLVCTVLVWTSNTVLEAKGEEAIGVQLSSIASNMADKFDRGMMSRISEIAFVSSLDLFRN
PSNPRAIRHTLDDLQEAVPYFTWIGFTDPTGTVRAGTNGLLEGADFSQRAVFQQGIQGPFTGNLHEAPMLAKALGASGAE
PMRFLDITFPVTDLAGAVVGMLSAHIDWAWARELEHAALESALSRQGLELLVVDHAGTVLLRPEGLALPKTLDLEALRHS
QTRPKGWTIETWPDGKVYLTGYARQRGYKAFAGFGWRILARQPVEIAFAPLAEVRHTLLLAGVVGGVIFGAIAWITAGAI
ARPLKRITEAADGLRDGAVGAALPHLTGSKEIERLSESLRLLINALTATDRRMGRMEKLAHNDLLTGLPNRAALGAYLDR
VVPALSNAQAAIAFLYLDLDGFKAVNDTLGHGAGDDLLKAAAGRILDCLRQGDMAIRLGGDEFVVIVNTSASSWRQESIR
VAERLLTALDGPFALPGGVRAKIGCSIGIAAWPDDHCDIEGALHHADIALYQAKRLGKGQSVVYADLPKSVLHDG

Sequences:

>Translated_555_residues
MAFGSWSLRAQVGLVFGSLVTLVCTVLVWTSNTVLEAKGEEAIGVQLSSIASNMADKFDRGMMSRISEIAFVSSLDLFRN
PSNPRAIRHTLDDLQEAVPYFTWIGFTDPTGTVRAGTNGLLEGADFSQRAVFQQGIQGPFTGNLHEAPMLAKALGASGAE
PMRFLDITFPVTDLAGAVVGMLSAHIDWAWARELEHAALESALSRQGLELLVVDHAGTVLLRPEGLALPKTLDLEALRHS
QTRPKGWTIETWPDGKVYLTGYARQRGYKAFAGFGWRILARQPVEIAFAPLAEVRHTLLLAGVVGGVIFGAIAWITAGAI
ARPLKRITEAADGLRDGAVGAALPHLTGSKEIERLSESLRLLINALTATDRRMGRMEKLAHNDLLTGLPNRAALGAYLDR
VVPALSNAQAAIAFLYLDLDGFKAVNDTLGHGAGDDLLKAAAGRILDCLRQGDMAIRLGGDEFVVIVNTSASSWRQESIR
VAERLLTALDGPFALPGGVRAKIGCSIGIAAWPDDHCDIEGALHHADIALYQAKRLGKGQSVVYADLPKSVLHDG
>Mature_554_residues
AFGSWSLRAQVGLVFGSLVTLVCTVLVWTSNTVLEAKGEEAIGVQLSSIASNMADKFDRGMMSRISEIAFVSSLDLFRNP
SNPRAIRHTLDDLQEAVPYFTWIGFTDPTGTVRAGTNGLLEGADFSQRAVFQQGIQGPFTGNLHEAPMLAKALGASGAEP
MRFLDITFPVTDLAGAVVGMLSAHIDWAWARELEHAALESALSRQGLELLVVDHAGTVLLRPEGLALPKTLDLEALRHSQ
TRPKGWTIETWPDGKVYLTGYARQRGYKAFAGFGWRILARQPVEIAFAPLAEVRHTLLLAGVVGGVIFGAIAWITAGAIA
RPLKRITEAADGLRDGAVGAALPHLTGSKEIERLSESLRLLINALTATDRRMGRMEKLAHNDLLTGLPNRAALGAYLDRV
VPALSNAQAAIAFLYLDLDGFKAVNDTLGHGAGDDLLKAAAGRILDCLRQGDMAIRLGGDEFVVIVNTSASSWRQESIRV
AERLLTALDGPFALPGGVRAKIGCSIGIAAWPDDHCDIEGALHHADIALYQAKRLGKGQSVVYADLPKSVLHDG

Specific function: Part of a 2 protein system that seems to be dedicated to transcription of csgD. This protein decreases csgD transcription and thus decreases expression of adhesive curli fimbriae genes csgEFG, csgBAC/ymaD and adrA (yaic). Activity of this protein is antag

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=181, Percent_Identity=39.7790055248619, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI1788381, Length=185, Percent_Identity=33.5135135135135, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI145693134, Length=159, Percent_Identity=35.2201257861635, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI87081977, Length=160, Percent_Identity=35, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI87082007, Length=163, Percent_Identity=34.9693251533742, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1786584, Length=172, Percent_Identity=31.9767441860465, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1788956, Length=219, Percent_Identity=29.6803652968037, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1787262, Length=198, Percent_Identity=29.2929292929293, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI87081974, Length=182, Percent_Identity=30.2197802197802, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI1787816, Length=176, Percent_Identity=30.1136363636364, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI87081881, Length=226, Percent_Identity=30.9734513274336, Blast_Score=74, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR000014
- InterPro:   IPR013767 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF00989 PAS [H]

EC number: =3.1.4.52 [H]

Molecular weight: Translated: 59482; Mature: 59351

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS50885 HAMP ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFGSWSLRAQVGLVFGSLVTLVCTVLVWTSNTVLEAKGEEAIGVQLSSIASNMADKFDR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHEEHHHHHHHHHHHHHH
GMMSRISEIAFVSSLDLFRNPSNPRAIRHTLDDLQEAVPYFTWIGFTDPTGTVRAGTNGL
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCEECCCCCC
LEGADFSQRAVFQQGIQGPFTGNLHEAPMLAKALGASGAEPMRFLDITFPVTDLAGAVVG
CCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEEECCHHHHHHHHHH
MLSAHIDWAWARELEHAALESALSRQGLELLVVDHAGTVLLRPEGLALPKTLDLEALRHS
HHHHHCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEECCCCCCCCCCCCHHHHHCC
QTRPKGWTIETWPDGKVYLTGYARQRGYKAFAGFGWRILARQPVEIAFAPLAEVRHTLLL
CCCCCCCEEEECCCCCEEEEEEHHHCCCCHHHCCCEEEECCCCHHHHHHHHHHHHHHHHH
AGVVGGVIFGAIAWITAGAIARPLKRITEAADGLRDGAVGAALPHLTGSKEIERLSESLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCHHHHHHHHHHHH
LLINALTATDRRMGRMEKLAHNDLLTGLPNRAALGAYLDRVVPALSNAQAAIAFLYLDLD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEECC
GFKAVNDTLGHGAGDDLLKAAAGRILDCLRQGDMAIRLGGDEFVVIVNTSASSWRQESIR
CCHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCEEEEEEECCCHHHHHHHHH
VAERLLTALDGPFALPGGVRAKIGCSIGIAAWPDDHCDIEGALHHADIALYQAKRLGKGQ
HHHHHHHHHCCCCCCCCCCEEEECCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCC
SVVYADLPKSVLHDG
EEEEECCCHHHHCCC
>Mature Secondary Structure 
AFGSWSLRAQVGLVFGSLVTLVCTVLVWTSNTVLEAKGEEAIGVQLSSIASNMADKFDR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHEEHHHHHHHHHHHHHH
GMMSRISEIAFVSSLDLFRNPSNPRAIRHTLDDLQEAVPYFTWIGFTDPTGTVRAGTNGL
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCEECCCCCC
LEGADFSQRAVFQQGIQGPFTGNLHEAPMLAKALGASGAEPMRFLDITFPVTDLAGAVVG
CCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEEECCHHHHHHHHHH
MLSAHIDWAWARELEHAALESALSRQGLELLVVDHAGTVLLRPEGLALPKTLDLEALRHS
HHHHHCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEECCCCCCCCCCCCHHHHHCC
QTRPKGWTIETWPDGKVYLTGYARQRGYKAFAGFGWRILARQPVEIAFAPLAEVRHTLLL
CCCCCCCEEEECCCCCEEEEEEHHHCCCCHHHCCCEEEECCCCHHHHHHHHHHHHHHHHH
AGVVGGVIFGAIAWITAGAIARPLKRITEAADGLRDGAVGAALPHLTGSKEIERLSESLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCHHHHHHHHHHHH
LLINALTATDRRMGRMEKLAHNDLLTGLPNRAALGAYLDRVVPALSNAQAAIAFLYLDLD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEECC
GFKAVNDTLGHGAGDDLLKAAAGRILDCLRQGDMAIRLGGDEFVVIVNTSASSWRQESIR
CCHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCEEEEEEECCCHHHHHHHHH
VAERLLTALDGPFALPGGVRAKIGCSIGIAAWPDDHCDIEGALHHADIALYQAKRLGKGQ
HHHHHHHHHCCCCCCCCCCEEEECCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCC
SVVYADLPKSVLHDG
EEEEECCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]