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The map label for this gene is ygbM [C]

Identifier: 83593838

GI number: 83593838

Start: 2909246

End: 2910040

Strand: Reverse

Name: ygbM [C]

Synonym: Rru_A2503

Alternate gene names: 83593838

Gene position: 2910040-2909246 (Counterclockwise)

Preceding gene: 83593841

Following gene: 83593832

Centisome position: 66.85

GC content: 66.29

Gene sequence:

>795_bases
ATGCCACGCTTCGCGGCCAATCTTTCCACGCTCTTTACCGACCGCCCGCTCGAGGAGCGGTTCGCCGCCGCCGCGGCCTG
CGGCTTTCGGGGGGTGGAGCTGCAGTTTCCCTATACCTTGGCCCCGGAACGGCTGGGCGATCTGGCGGCGATGAACCGGC
TTGATGTCGTGCTCTTCAACGCCCCGCCGGGCGATTGGGCGGCCGGCGAGCGCGGCCTTGCCGCCCTGCCGGGCCGCCAG
AGCGAGTTCCGCGACAGCCTGGAGGTCGTGCTGCCCTATGTGGAACTGGCCGGCTGCGAGCGCGTCCACGTGATGGCCGG
GGTGGTCGCCGAGGACGACTGGCCCGTCGCCCTGGAAACCTATGTCGAAAATCTGGCCTATGCCGCCGATCTGTTCGCCG
AGCGCGGTGTGAAGGTGCTGATCGAGGCGGTCAATACCGAGGACATGCCGGGCTATTTCCTGTCGCGTCCCGATGACGCC
TTGCAGGTCATCGAAGAGGTCGGCCACAAGAACCTGCATGTGCTTTACGATTTTTATCACGCCCAGATCGTTCAGGGCGG
GCTGACGGATTTTCTGGAATCCAACATCGAGCGCATCGCCCATGTCCAGGTCGCCGGGGTTCCCGGACGGCGCGAACCCG
ATGCCAATGGCGAGATCAACTGGCCCTATCTGTTCAATCTGCTCGATGCCCACGGCTTCCCCGGTTGGGTCGGCTGCGAG
TACACCCCGCGCGCCGGCACCGAGGCCGGCCTGCGCTGGGCGCGGGATTTCGGGATCAGCGCTCCGGCGGCGTGA

Upstream 100 bases:

>100_bases
GGGCGACATAACGCAAACGACCTTCGCTCGCCATGATATAGCGCAAGGCGAGAATCGTGCATACTCCCGCCACCCCCCCT
TTGTCCAGGACAAGCACCCA

Downstream 100 bases:

>100_bases
TCAGTGGGGAAGCGGCCGGGGAGGCTGGCGGAGGCTTGGTCATCATGCTTTCGGCGGGCGGGTGTTCGGCGGGCGGGTGT
TCGGGGCGGCTGGCGATGAA

Product: hydroxypyruvate isomerase

Products: 2-hydroxy-3-oxopropanoate

Alternate protein names: ORF4 [H]

Number of amino acids: Translated: 264; Mature: 263

Protein sequence:

>264_residues
MPRFAANLSTLFTDRPLEERFAAAAACGFRGVELQFPYTLAPERLGDLAAMNRLDVVLFNAPPGDWAAGERGLAALPGRQ
SEFRDSLEVVLPYVELAGCERVHVMAGVVAEDDWPVALETYVENLAYAADLFAERGVKVLIEAVNTEDMPGYFLSRPDDA
LQVIEEVGHKNLHVLYDFYHAQIVQGGLTDFLESNIERIAHVQVAGVPGRREPDANGEINWPYLFNLLDAHGFPGWVGCE
YTPRAGTEAGLRWARDFGISAPAA

Sequences:

>Translated_264_residues
MPRFAANLSTLFTDRPLEERFAAAAACGFRGVELQFPYTLAPERLGDLAAMNRLDVVLFNAPPGDWAAGERGLAALPGRQ
SEFRDSLEVVLPYVELAGCERVHVMAGVVAEDDWPVALETYVENLAYAADLFAERGVKVLIEAVNTEDMPGYFLSRPDDA
LQVIEEVGHKNLHVLYDFYHAQIVQGGLTDFLESNIERIAHVQVAGVPGRREPDANGEINWPYLFNLLDAHGFPGWVGCE
YTPRAGTEAGLRWARDFGISAPAA
>Mature_263_residues
PRFAANLSTLFTDRPLEERFAAAAACGFRGVELQFPYTLAPERLGDLAAMNRLDVVLFNAPPGDWAAGERGLAALPGRQS
EFRDSLEVVLPYVELAGCERVHVMAGVVAEDDWPVALETYVENLAYAADLFAERGVKVLIEAVNTEDMPGYFLSRPDDAL
QVIEEVGHKNLHVLYDFYHAQIVQGGLTDFLESNIERIAHVQVAGVPGRREPDANGEINWPYLFNLLDAHGFPGWVGCEY
TPRAGTEAGLRWARDFGISAPAA

Specific function: Unknown

COG id: COG3622

COG function: function code G; Hydroxypyruvate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hyi family [H]

Homologues:

Organism=Homo sapiens, GI300068962, Length=262, Percent_Identity=43.5114503816794, Blast_Score=204, Evalue=7e-53,
Organism=Homo sapiens, GI300068964, Length=243, Percent_Identity=42.798353909465, Blast_Score=181, Evalue=5e-46,
Organism=Escherichia coli, GI1789095, Length=254, Percent_Identity=47.244094488189, Blast_Score=229, Evalue=2e-61,
Organism=Escherichia coli, GI1786718, Length=254, Percent_Identity=44.0944881889764, Blast_Score=222, Evalue=2e-59,
Organism=Caenorhabditis elegans, GI17552022, Length=260, Percent_Identity=40, Blast_Score=190, Evalue=5e-49,
Organism=Drosophila melanogaster, GI17530883, Length=263, Percent_Identity=32.6996197718631, Blast_Score=149, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013022
- InterPro:   IPR012307 [H]

Pfam domain/function: PF01261 AP_endonuc_2 [H]

EC number: 5.3.1.22

Molecular weight: Translated: 29018; Mature: 28887

Theoretical pI: Translated: 4.33; Mature: 4.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRFAANLSTLFTDRPLEERFAAAAACGFRGVELQFPYTLAPERLGDLAAMNRLDVVLFN
CCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEECCCEECHHHHHHHHHHCCEEEEEEE
APPGDWAAGERGLAALPGRQSEFRDSLEVVLPYVELAGCERVHVMAGVVAEDDWPVALET
CCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCHHHHH
YVENLAYAADLFAERGVKVLIEAVNTEDMPGYFLSRPDDALQVIEEVGHKNLHVLYDFYH
HHHHHHHHHHHHHHCCHHEEHHHHCCCCCCCHHCCCCHHHHHHHHHHCCCCEEEEHHHHH
AQIVQGGLTDFLESNIERIAHVQVAGVPGRREPDANGEINWPYLFNLLDAHGFPGWVGCE
HHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCC
YTPRAGTEAGLRWARDFGISAPAA
CCCCCCCHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
PRFAANLSTLFTDRPLEERFAAAAACGFRGVELQFPYTLAPERLGDLAAMNRLDVVLFN
CCHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEECCCEECHHHHHHHHHHCCEEEEEEE
APPGDWAAGERGLAALPGRQSEFRDSLEVVLPYVELAGCERVHVMAGVVAEDDWPVALET
CCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCHHHHH
YVENLAYAADLFAERGVKVLIEAVNTEDMPGYFLSRPDDALQVIEEVGHKNLHVLYDFYH
HHHHHHHHHHHHHHCCHHEEHHHHCCCCCCCHHCCCCHHHHHHHHHHCCCCEEEEHHHHH
AQIVQGGLTDFLESNIERIAHVQVAGVPGRREPDANGEINWPYLFNLLDAHGFPGWVGCE
HHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCC
YTPRAGTEAGLRWARDFGISAPAA
CCCCCCCHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: hydroxypyruvate

Specific reaction: hydroxypyruvate = 2-hydroxy-3-oxopropanoate; Other Name(s): hydroxypyruvate ketol-isomerase

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7851418 [H]