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The map label for this gene is caiD [C]

Identifier: 83593841

GI number: 83593841

Start: 2912866

End: 2913648

Strand: Reverse

Name: caiD [C]

Synonym: Rru_A2506

Alternate gene names: 83593841

Gene position: 2913648-2912866 (Counterclockwise)

Preceding gene: 83593847

Following gene: 83593838

Centisome position: 66.94

GC content: 70.88

Gene sequence:

>783_bases
GTGCTCGTCACCATCGAAGGCGCCGTCGCCACTTTGGTTCTTAATCGGCCCGATCGCCTGAACGCCCTGGATCTGCCCCT
GTGGCGGGCGCTTGGCGAGGCGGTGGCGGTCTTGGCCGGGCGCTTGGCCGAGGGCGAGGATCTGCGCTGTCTGGTGCTGC
GCGGCGCCGGGGGGCGGGCCTTCGCCGCCGGCGCCGATATCGGCGAATTCGCCACCCTGCGCGCCACCGCCGCCCAGGCG
CAAGACTATGATCGGGTGATGCGCCGGGCCCTGGACGGCGTGCGCGCCTTCCCCGTGCCGGTGATCGCGGCGATCGAGGG
GGCTTGCGTCGGCGCCGGTCTGGAACTGGCCTGCATGGCCGATCTCCGCCTGTCCAACGCCTCGGGGCGCTTCGGCGTGC
CGATCAACCGCATCGGCGTGGTGATGGCCTATCCCGAGATCGGCGGATTGCTACGGCTGGCCGGTCCGGCAAACACCCTG
GAGATCCTGCTGGAAGGCCGGGTTTTCGGCGCCGACGAGGCGCTGCGCATGGGGTTGGTCAATCGGGTCGTCGCCGATGG
GGCGTTCGCCGCCCACCTCGACGAGACCGTCAGCCGTCTGGTCCGCGCCGCCCCCGGGGTCAACGCCAGCCACAAGGCCT
TCGTCACCCGCCTGCTGGCCGAGGGGCCGCCGCCGGGCGAGGCCGAGATGGCCGAATGCTATCGCTTCTTGGAAACCGAA
GACTACCGAGAAGGGGTGGCGGCCTTCCTGGCCAAGCGGCCGCCGGTCTTCAAGGGGCGCTAA

Upstream 100 bases:

>100_bases
CGGCCGCTCTTTTCAAGAGCGCCGCCGCCGGGAAAGCAAGGAGAGCCGATCGATGACCGCCAGCCAGTCGGGTCCTGTCG
GGGCCGCGCCGTCCGCAAGC

Downstream 100 bases:

>100_bases
CGGCTTAGGCTGGCGGCCTGCCGGCGCAGCAAGGTGGCGTTGCGGTCGGGGTGGACGGGCAGCAGGTAGCGGCCGACCTC
GTGGAAGGGCAAAGGGGCGA

Product: enoyl-CoA hydratase / short chain enoyl-CoA hydratase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MLVTIEGAVATLVLNRPDRLNALDLPLWRALGEAVAVLAGRLAEGEDLRCLVLRGAGGRAFAAGADIGEFATLRATAAQA
QDYDRVMRRALDGVRAFPVPVIAAIEGACVGAGLELACMADLRLSNASGRFGVPINRIGVVMAYPEIGGLLRLAGPANTL
EILLEGRVFGADEALRMGLVNRVVADGAFAAHLDETVSRLVRAAPGVNASHKAFVTRLLAEGPPPGEAEMAECYRFLETE
DYREGVAAFLAKRPPVFKGR

Sequences:

>Translated_260_residues
MLVTIEGAVATLVLNRPDRLNALDLPLWRALGEAVAVLAGRLAEGEDLRCLVLRGAGGRAFAAGADIGEFATLRATAAQA
QDYDRVMRRALDGVRAFPVPVIAAIEGACVGAGLELACMADLRLSNASGRFGVPINRIGVVMAYPEIGGLLRLAGPANTL
EILLEGRVFGADEALRMGLVNRVVADGAFAAHLDETVSRLVRAAPGVNASHKAFVTRLLAEGPPPGEAEMAECYRFLETE
DYREGVAAFLAKRPPVFKGR
>Mature_260_residues
MLVTIEGAVATLVLNRPDRLNALDLPLWRALGEAVAVLAGRLAEGEDLRCLVLRGAGGRAFAAGADIGEFATLRATAAQA
QDYDRVMRRALDGVRAFPVPVIAAIEGACVGAGLELACMADLRLSNASGRFGVPINRIGVVMAYPEIGGLLRLAGPANTL
EILLEGRVFGADEALRMGLVNRVVADGAFAAHLDETVSRLVRAAPGVNASHKAFVTRLLAEGPPPGEAEMAECYRFLETE
DYREGVAAFLAKRPPVFKGR

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=266, Percent_Identity=32.3308270676692, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI31542718, Length=258, Percent_Identity=27.1317829457364, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI70995211, Length=205, Percent_Identity=28.780487804878, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI20127408, Length=189, Percent_Identity=30.1587301587302, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI68989263, Length=180, Percent_Identity=30, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI4502327, Length=260, Percent_Identity=28.4615384615385, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI221142681, Length=275, Percent_Identity=33.0909090909091, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI1790281, Length=187, Percent_Identity=35.2941176470588, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1787659, Length=264, Percent_Identity=31.0606060606061, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI87082183, Length=271, Percent_Identity=29.520295202952, Blast_Score=87, Evalue=7e-19,
Organism=Escherichia coli, GI1787660, Length=280, Percent_Identity=31.0714285714286, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788682, Length=182, Percent_Identity=32.967032967033, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1788597, Length=269, Percent_Identity=27.8810408921933, Blast_Score=68, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI25145438, Length=253, Percent_Identity=31.6205533596838, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17560910, Length=186, Percent_Identity=35.4838709677419, Blast_Score=87, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17554946, Length=264, Percent_Identity=31.0606060606061, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17540306, Length=263, Percent_Identity=26.9961977186312, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17536985, Length=194, Percent_Identity=28.3505154639175, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17535521, Length=263, Percent_Identity=26.2357414448669, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17534483, Length=186, Percent_Identity=28.494623655914, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17558304, Length=188, Percent_Identity=29.2553191489362, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17540714, Length=179, Percent_Identity=28.4916201117318, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24653139, Length=263, Percent_Identity=31.5589353612167, Blast_Score=94, Evalue=9e-20,
Organism=Drosophila melanogaster, GI20129971, Length=267, Percent_Identity=29.9625468164794, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24653477, Length=267, Percent_Identity=29.9625468164794, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI19922422, Length=264, Percent_Identity=25.3787878787879, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI19920382, Length=267, Percent_Identity=29.2134831460674, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24650670, Length=197, Percent_Identity=35.0253807106599, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI21357171, Length=201, Percent_Identity=33.8308457711443, Blast_Score=75, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 27443; Mature: 27443

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVTIEGAVATLVLNRPDRLNALDLPLWRALGEAVAVLAGRLAEGEDLRCLVLRGAGGRA
CEEEECCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCE
FAAGADIGEFATLRATAAQAQDYDRVMRRALDGVRAFPVPVIAAIEGACVGAGLELACMA
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCHHCCCCCEEEEEE
DLRLSNASGRFGVPINRIGVVMAYPEIGGLLRLAGPANTLEILLEGRVFGADEALRMGLV
EEEECCCCCCCCCCHHHHEEEEECCCCCCEEEECCCCCEEHHEEECCEECCHHHHHHHHH
NRVVADGAFAAHLDETVSRLVRAAPGVNASHKAFVTRLLAEGPPPGEAEMAECYRFLETE
HHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCH
DYREGVAAFLAKRPPVFKGR
HHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MLVTIEGAVATLVLNRPDRLNALDLPLWRALGEAVAVLAGRLAEGEDLRCLVLRGAGGRA
CEEEECCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCE
FAAGADIGEFATLRATAAQAQDYDRVMRRALDGVRAFPVPVIAAIEGACVGAGLELACMA
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCHHCCCCCEEEEEE
DLRLSNASGRFGVPINRIGVVMAYPEIGGLLRLAGPANTLEILLEGRVFGADEALRMGLV
EEEECCCCCCCCCCHHHHEEEEECCCCCCEEEECCCCCEEHHEEECCEECCHHHHHHHHH
NRVVADGAFAAHLDETVSRLVRAAPGVNASHKAFVTRLLAEGPPPGEAEMAECYRFLETE
HHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCH
DYREGVAAFLAKRPPVFKGR
HHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA