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The map label for this gene is argC

Identifier: 83593756

GI number: 83593756

Start: 2820294

End: 2821352

Strand: Reverse

Name: argC

Synonym: Rru_A2421

Alternate gene names: 83593756

Gene position: 2821352-2820294 (Counterclockwise)

Preceding gene: 83593758

Following gene: 83593755

Centisome position: 64.82

GC content: 66.19

Gene sequence:

>1059_bases
ATGAGCGAACGGGTCAATGTCGCCATCCTCGGGGCCAGCGGCTATACGGGCGCCGAACTCGTTCGCCTGCTCGCCCGCCA
TCCGCGCGTGACCCTGGCGGCGCTGACCGCCAACCGCAAGGCCGGCCAAGCCTTCGCCTCGGTCTTTCCCCATCTTGGCG
GGCTCGATCTGCCGGTTTTGTCGACCATCGAGGCGGTCGACTGGTCGGCGATCGATTTCGTCTTTTGCGCCCTACCCCAT
GGCACGACGCAGACCATCATCGGCGATCTGCTGAACGGCCCCCACGGCGGGCGGCTGCGCATCGCCGATTTGTCGGCCGA
TTTCCGGCTGGCCGATCCAATGGTCTATCAAACCTGGTACGGCCATGCCCATGAGGCGGTCGAGCTTCAGAAGGAGGCCG
TTTACGGCCTGACCGAGATCAATCGCGCCGCCATCGCCACGGCCCGATTGGTGGCGGTGCCCGGCTGCTATCCGACCAGC
GCCCAATTGCCGCTGATCCCGCTGCTGCGCGCCGGCCTGATCGATCCCGACGCCATCATCATCGATGCCAAATCCGGCGC
CTCGGGGGCGGGGCGCGACGCCAAGGAAGGCTCGCTCCATTGCGAGGTGTCCGAGGGCATCCACGCCTATGGGGTGGGCA
CCCATCGCCATGGCCCCGAGATCGAGCAGGGTCTGAGTCTGGCCGTCGGGCGGCCGGTGGCGGTGACTTTCACCCCCCAT
CTGATGCCGATGAACCGGGGTATCTTAAGCACCATCTATCTGCGTGCCACCGCCGGCAATGACGCCACCACCCTGCGTCA
GGCGCTGAGCGCGGCCTATGCCGACGAGGCCTTCGTGCGGGTGGTGCCCGAAGGGGTGTCGCCCCATACCCGTCATGTGC
GCGGGTCGAATTTCGTGCTGATCGGCGTTCACGCCGACCGGGTGCCCGGCCGGGTGATCGTGACCTGCGTCGAGGATAAT
CTGGTCAAGGGCGCCTCGGGTCAGGCGATCCAGGATATGAACGTCATGCTGGGCTTCCCCGAAACCCTGGGGCTTGATCA
GCAGCCGCTGTTTCCCTGA

Upstream 100 bases:

>100_bases
TGGGGGCGATGTATCCAATCTTTCCGGCCATTTTCATGTTTTCGCCGGCCGATCAAGACCGGCGCCGGGAATTTTTCCCT
ATCTTACAAGGATCTTGGTT

Downstream 100 bases:

>100_bases
GCGACATAAGGGGCGTCCGTCGGGCGCCCCTTTTTCATTGAAGAAAGGGTCGCGACCATGTCCGCCTCCGAGCCTCCCGC
CGTTCCCTTGGGCACTCCCG

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase

Number of amino acids: Translated: 352; Mature: 351

Protein sequence:

>352_residues
MSERVNVAILGASGYTGAELVRLLARHPRVTLAALTANRKAGQAFASVFPHLGGLDLPVLSTIEAVDWSAIDFVFCALPH
GTTQTIIGDLLNGPHGGRLRIADLSADFRLADPMVYQTWYGHAHEAVELQKEAVYGLTEINRAAIATARLVAVPGCYPTS
AQLPLIPLLRAGLIDPDAIIIDAKSGASGAGRDAKEGSLHCEVSEGIHAYGVGTHRHGPEIEQGLSLAVGRPVAVTFTPH
LMPMNRGILSTIYLRATAGNDATTLRQALSAAYADEAFVRVVPEGVSPHTRHVRGSNFVLIGVHADRVPGRVIVTCVEDN
LVKGASGQAIQDMNVMLGFPETLGLDQQPLFP

Sequences:

>Translated_352_residues
MSERVNVAILGASGYTGAELVRLLARHPRVTLAALTANRKAGQAFASVFPHLGGLDLPVLSTIEAVDWSAIDFVFCALPH
GTTQTIIGDLLNGPHGGRLRIADLSADFRLADPMVYQTWYGHAHEAVELQKEAVYGLTEINRAAIATARLVAVPGCYPTS
AQLPLIPLLRAGLIDPDAIIIDAKSGASGAGRDAKEGSLHCEVSEGIHAYGVGTHRHGPEIEQGLSLAVGRPVAVTFTPH
LMPMNRGILSTIYLRATAGNDATTLRQALSAAYADEAFVRVVPEGVSPHTRHVRGSNFVLIGVHADRVPGRVIVTCVEDN
LVKGASGQAIQDMNVMLGFPETLGLDQQPLFP
>Mature_351_residues
SERVNVAILGASGYTGAELVRLLARHPRVTLAALTANRKAGQAFASVFPHLGGLDLPVLSTIEAVDWSAIDFVFCALPHG
TTQTIIGDLLNGPHGGRLRIADLSADFRLADPMVYQTWYGHAHEAVELQKEAVYGLTEINRAAIATARLVAVPGCYPTSA
QLPLIPLLRAGLIDPDAIIIDAKSGASGAGRDAKEGSLHCEVSEGIHAYGVGTHRHGPEIEQGLSLAVGRPVAVTFTPHL
MPMNRGILSTIYLRATAGNDATTLRQALSAAYADEAFVRVVPEGVSPHTRHVRGSNFVLIGVHADRVPGRVIVTCVEDNL
VKGASGQAIQDMNVMLGFPETLGLDQQPLFP

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790396, Length=348, Percent_Identity=40.5172413793103, Blast_Score=207, Evalue=1e-54,
Organism=Saccharomyces cerevisiae, GI6320913, Length=355, Percent_Identity=29.2957746478873, Blast_Score=111, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGC_RHORT (Q2RRM4)

Other databases:

- EMBL:   CP000230
- RefSeq:   YP_427508.1
- HSSP:   Q8ZKL8
- ProteinModelPortal:   Q2RRM4
- SMR:   Q2RRM4
- STRING:   Q2RRM4
- GeneID:   3835855
- GenomeReviews:   CP000230_GR
- KEGG:   rru:Rru_A2421
- NMPDR:   fig|1085.1.peg.70
- eggNOG:   COG0002
- HOGENOM:   HBG294213
- OMA:   VCRIAVH
- PhylomeDB:   Q2RRM4
- ProtClustDB:   PRK00436
- BioCyc:   RRUB269796:RRU_A2421-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00150
- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280
- Gene3D:   G3DSA:3.40.50.720
- SMART:   SM00859
- TIGRFAMs:   TIGR01850

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC

EC number: =1.2.1.38

Molecular weight: Translated: 37298; Mature: 37167

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS01224 ARGC

Important sites: ACT_SITE 156-156

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSERVNVAILGASGYTGAELVRLLARHPRVTLAALTANRKAGQAFASVFPHLGGLDLPVL
CCCCEEEEEEECCCCCHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHCCCCCCCCHHH
STIEAVDWSAIDFVFCALPHGTTQTIIGDLLNGPHGGRLRIADLSADFRLADPMVYQTWY
HHHHHCCCCHHEEEEEECCCCCHHHHHHHHHCCCCCCEEEEEECCCCCEECCCEEEEHHC
GHAHEAVELQKEAVYGLTEINRAAIATARLVAVPGCYPTSAQLPLIPLLRAGLIDPDAII
CCHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCCHHHHHHHCCCCCCEEE
IDAKSGASGAGRDAKEGSLHCEVSEGIHAYGVGTHRHGPEIEQGLSLAVGRPVAVTFTPH
EECCCCCCCCCCCCCCCCEEEECCCCEEEEECCCCCCCCCHHHCCEEECCCCEEEEECCC
LMPMNRGILSTIYLRATAGNDATTLRQALSAAYADEAFVRVVPEGVSPHTRHVRGSNFVL
CCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEECCCCEEE
IGVHADRVPGRVIVTCVEDNLVKGASGQAIQDMNVMLGFPETLGLDQQPLFP
EEEECCCCCCEEEEEEECCCCCCCCCCCEEECCCEEEECHHHCCCCCCCCCC
>Mature Secondary Structure 
SERVNVAILGASGYTGAELVRLLARHPRVTLAALTANRKAGQAFASVFPHLGGLDLPVL
CCCEEEEEEECCCCCHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHCCCCCCCCHHH
STIEAVDWSAIDFVFCALPHGTTQTIIGDLLNGPHGGRLRIADLSADFRLADPMVYQTWY
HHHHHCCCCHHEEEEEECCCCCHHHHHHHHHCCCCCCEEEEEECCCCCEECCCEEEEHHC
GHAHEAVELQKEAVYGLTEINRAAIATARLVAVPGCYPTSAQLPLIPLLRAGLIDPDAII
CCHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCCHHHHHHHCCCCCCEEE
IDAKSGASGAGRDAKEGSLHCEVSEGIHAYGVGTHRHGPEIEQGLSLAVGRPVAVTFTPH
EECCCCCCCCCCCCCCCCEEEECCCCEEEEECCCCCCCCCHHHCCEEECCCCEEEEECCC
LMPMNRGILSTIYLRATAGNDATTLRQALSAAYADEAFVRVVPEGVSPHTRHVRGSNFVL
CCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEECCCCEEE
IGVHADRVPGRVIVTCVEDNLVKGASGQAIQDMNVMLGFPETLGLDQQPLFP
EEEECCCCCCEEEEEEECCCCCCCCCCCEEECCCEEEECHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA