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The map label for this gene is glnA [H]

Identifier: 83593421

GI number: 83593421

Start: 2414176

End: 2415585

Strand: Direct

Name: glnA [H]

Synonym: Rru_A2086

Alternate gene names: 83593421

Gene position: 2414176-2415585 (Clockwise)

Preceding gene: 83593420

Following gene: 83593422

Centisome position: 55.46

GC content: 60.43

Gene sequence:

>1410_bases
ATGTCCGACGTTAAGACCATTCTCGAAATGATTAAGGAAAACGACGTTAAGTTCGTCGATTTCCGCTTCACCGATCCCAA
GGGCAAGTGGCAGCATACCGCCCAGTACGTGACCACCATCGACGAGGAAAGCCTGGTCGAAGGCATCATGTTCGACGGTT
CGTCGATCGCCGGGTGGAAGGACATCAACGAGTCCGACATGATCCTGAAGCCCGACCTGAAGTCGGCCTTCATGGATCCG
TTCTCGGCTCAGCCGCAGCTCGTCTTGTTCTGCGACGTGCTCGAGCCCTCGACCGGGCAGCCCTATGAGCGTTGCCCGCG
CTCGATCGCCAAGAAGGCCCTGTCCTATCTGGCCTCGACCGGCATCGGCGACACCTCGTACTTCGGCCCGGAAGCCGAGT
TCTTCGTGTTCGACGACGTGCGCTTCGACGTGTCGATGAACCGCGTCATGTACGAAGTCGACAGCGAAGAAGGCCCCTAC
GTCACCGGCAAGATCTTCGACGAGGGCAACTACGGCCACCGTCCGCCGATCAAGGGCGGCTATTTCCCGGTTCCGCCGGT
GGACAGCGCCCAGGACCTGCGCGCCGAAATGCTCTCGACCATGGCCGAGATCGGCATGCCCGTCGAAAAGCACCACCACG
AAGTGGCGCCGTCGCAGCATGAACTGGGTGTTCGCTTCAACACCCTGATCGAAGCCGCCGACGACATGCAGAAGTACAAG
TATGTCGTTCACATGGTCGCCCATGCCTATGGCAAGACCGCGACCTTCATGCCCAAGCCGATCGCCGGCGACAACGGGTC
GGGCATGCACGTCCATCAGTCGATCTGGAAGGATGGCAAGCCGCTGTTCGCCGGTTCGGGCTATGCCGACCTGTCGGAAA
TGGCCCTTTACTACATCGGCGGCATCATCAAGCATGCCAAGGCGCTGAACGCCTTCACCAATCCGTCGACCAACTCGTAC
AAGCGCCTGATCCCCGGCTTCGAAGCCCCGGTTCTGCTGGCCTATTCGGCCCGCAACCGCTCGGCCTCCTGCCGTATCCC
CTATGTGGCGAGCCCGAAGGGCAAGCGCGTCGAGGTTCGTTTCCCCGATGCCGCCGCCAACCCCTATCTGGCTTTCGCCG
CCATGATGATGGCCGGCATCGACGGGATCGAGAACAAGATCCATCCGGGCGACCCGATGGACAAGAACCTCTACGACCTG
CCCCCCGAAGAACTGATGGGCATCCCCACGGTTTGCGGCTCTCTGCGCGAAGCGCTTGACAGCCTGAACGCCGACCGTGA
CTTCCTGAAGAAGGGTGGCGTCTTCACCGACGACATGATCGATGGCTATGTCGCCCTGAAGTGGGAAGAGGTTTACAACC
TCGAGCATGCTCCCCACCCGATCGAATACAAGATGTACTACTCGGTCTGA

Upstream 100 bases:

>100_bases
CCGGCTCCGGCCTTCGGGCCGGTTCGCCGGCGGTTCGGAGCGAATACGAACCGGATCGCCGCTTTCAGTCAGGCAGCACG
ACAAACTGGGAACTAAGGTC

Downstream 100 bases:

>100_bases
TCGGGCTCTTTCGGGTCCAGGGATATCGGGCGTCACCGCCCCTCCCTGGCCCCGACCTTTTTTGATAAAGCCCCGTCGGC
AGCCTGTCGGCGGGGCTTTA

Product: L-glutamine synthetase

Products: NA

Alternate protein names: Glutamate--ammonia ligase [H]

Number of amino acids: Translated: 469; Mature: 468

Protein sequence:

>469_residues
MSDVKTILEMIKENDVKFVDFRFTDPKGKWQHTAQYVTTIDEESLVEGIMFDGSSIAGWKDINESDMILKPDLKSAFMDP
FSAQPQLVLFCDVLEPSTGQPYERCPRSIAKKALSYLASTGIGDTSYFGPEAEFFVFDDVRFDVSMNRVMYEVDSEEGPY
VTGKIFDEGNYGHRPPIKGGYFPVPPVDSAQDLRAEMLSTMAEIGMPVEKHHHEVAPSQHELGVRFNTLIEAADDMQKYK
YVVHMVAHAYGKTATFMPKPIAGDNGSGMHVHQSIWKDGKPLFAGSGYADLSEMALYYIGGIIKHAKALNAFTNPSTNSY
KRLIPGFEAPVLLAYSARNRSASCRIPYVASPKGKRVEVRFPDAAANPYLAFAAMMMAGIDGIENKIHPGDPMDKNLYDL
PPEELMGIPTVCGSLREALDSLNADRDFLKKGGVFTDDMIDGYVALKWEEVYNLEHAPHPIEYKMYYSV

Sequences:

>Translated_469_residues
MSDVKTILEMIKENDVKFVDFRFTDPKGKWQHTAQYVTTIDEESLVEGIMFDGSSIAGWKDINESDMILKPDLKSAFMDP
FSAQPQLVLFCDVLEPSTGQPYERCPRSIAKKALSYLASTGIGDTSYFGPEAEFFVFDDVRFDVSMNRVMYEVDSEEGPY
VTGKIFDEGNYGHRPPIKGGYFPVPPVDSAQDLRAEMLSTMAEIGMPVEKHHHEVAPSQHELGVRFNTLIEAADDMQKYK
YVVHMVAHAYGKTATFMPKPIAGDNGSGMHVHQSIWKDGKPLFAGSGYADLSEMALYYIGGIIKHAKALNAFTNPSTNSY
KRLIPGFEAPVLLAYSARNRSASCRIPYVASPKGKRVEVRFPDAAANPYLAFAAMMMAGIDGIENKIHPGDPMDKNLYDL
PPEELMGIPTVCGSLREALDSLNADRDFLKKGGVFTDDMIDGYVALKWEEVYNLEHAPHPIEYKMYYSV
>Mature_468_residues
SDVKTILEMIKENDVKFVDFRFTDPKGKWQHTAQYVTTIDEESLVEGIMFDGSSIAGWKDINESDMILKPDLKSAFMDPF
SAQPQLVLFCDVLEPSTGQPYERCPRSIAKKALSYLASTGIGDTSYFGPEAEFFVFDDVRFDVSMNRVMYEVDSEEGPYV
TGKIFDEGNYGHRPPIKGGYFPVPPVDSAQDLRAEMLSTMAEIGMPVEKHHHEVAPSQHELGVRFNTLIEAADDMQKYKY
VVHMVAHAYGKTATFMPKPIAGDNGSGMHVHQSIWKDGKPLFAGSGYADLSEMALYYIGGIIKHAKALNAFTNPSTNSYK
RLIPGFEAPVLLAYSARNRSASCRIPYVASPKGKRVEVRFPDAAANPYLAFAAMMMAGIDGIENKIHPGDPMDKNLYDLP
PEELMGIPTVCGSLREALDSLNADRDFLKKGGVFTDDMIDGYVALKWEEVYNLEHAPHPIEYKMYYSV

Specific function: Unknown

COG id: COG0174

COG function: function code E; Glutamine synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamine synthetase family [H]

Homologues:

Organism=Homo sapiens, GI221307485, Length=489, Percent_Identity=24.3353783231084, Blast_Score=92, Evalue=7e-19,
Organism=Escherichia coli, GI1790301, Length=464, Percent_Identity=62.9310344827586, Blast_Score=613, Evalue=1e-177,
Organism=Escherichia coli, GI87081870, Length=409, Percent_Identity=25.6723716381418, Blast_Score=98, Evalue=1e-21,
Organism=Drosophila melanogaster, GI281360453, Length=334, Percent_Identity=24.8502994011976, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17136208, Length=334, Percent_Identity=24.8502994011976, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24580558, Length=334, Percent_Identity=24.8502994011976, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 15324 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal medi

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008147
- InterPro:   IPR014746
- InterPro:   IPR008146
- InterPro:   IPR004809
- InterPro:   IPR001637 [H]

Pfam domain/function: PF00120 Gln-synt_C; PF03951 Gln-synt_N [H]

EC number: =6.3.1.2 [H]

Molecular weight: Translated: 52309; Mature: 52178

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS00180 GLNA_1 ; PS00181 GLNA_ATP ; PS00182 GLNA_ADENYLATION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDVKTILEMIKENDVKFVDFRFTDPKGKWQHTAQYVTTIDEESLVEGIMFDGSSIAGWK
CCHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCC
DINESDMILKPDLKSAFMDPFSAQPQLVLFCDVLEPSTGQPYERCPRSIAKKALSYLAST
CCCCCCCEECCCHHHHHCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHC
GIGDTSYFGPEAEFFVFDDVRFDVSMNRVMYEVDSEEGPYVTGKIFDEGNYGHRPPIKGG
CCCCCCCCCCCCCEEEEECEEEEEEECEEEEEECCCCCCEEEEEEEECCCCCCCCCCCCC
YFPVPPVDSAQDLRAEMLSTMAEIGMPVEKHHHEVAPSQHELGVRFNTLIEAADDMQKYK
CCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHH
YVVHMVAHAYGKTATFMPKPIAGDNGSGMHVHQSIWKDGKPLFAGSGYADLSEMALYYIG
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCEECCCCCCCHHHHHHHHHH
GIIKHAKALNAFTNPSTNSYKRLIPGFEAPVLLAYSARNRSASCRIPYVASPKGKRVEVR
HHHHHHHHHHHCCCCCCCCHHHHCCCCCCCEEEEEECCCCCCCEECCEEECCCCCEEEEE
FPDAAANPYLAFAAMMMAGIDGIENKIHPGDPMDKNLYDLPPEELMGIPTVCGSLREALD
CCCCCCCHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHH
SLNADRDFLKKGGVFTDDMIDGYVALKWEEVYNLEHAPHPIEYKMYYSV
HCCCCHHHHHHCCCCCHHHHCCEEEEEEHHHHCCCCCCCCEEEEEEEEC
>Mature Secondary Structure 
SDVKTILEMIKENDVKFVDFRFTDPKGKWQHTAQYVTTIDEESLVEGIMFDGSSIAGWK
CHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCC
DINESDMILKPDLKSAFMDPFSAQPQLVLFCDVLEPSTGQPYERCPRSIAKKALSYLAST
CCCCCCCEECCCHHHHHCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHC
GIGDTSYFGPEAEFFVFDDVRFDVSMNRVMYEVDSEEGPYVTGKIFDEGNYGHRPPIKGG
CCCCCCCCCCCCCEEEEECEEEEEEECEEEEEECCCCCCEEEEEEEECCCCCCCCCCCCC
YFPVPPVDSAQDLRAEMLSTMAEIGMPVEKHHHEVAPSQHELGVRFNTLIEAADDMQKYK
CCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHH
YVVHMVAHAYGKTATFMPKPIAGDNGSGMHVHQSIWKDGKPLFAGSGYADLSEMALYYIG
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCEECCCCCCCHHHHHHHHHH
GIIKHAKALNAFTNPSTNSYKRLIPGFEAPVLLAYSARNRSASCRIPYVASPKGKRVEVR
HHHHHHHHHHHCCCCCCCCHHHHCCCCCCCEEEEEECCCCCCCEECCEEECCCCCEEEEE
FPDAAANPYLAFAAMMMAGIDGIENKIHPGDPMDKNLYDLPPEELMGIPTVCGSLREALD
CCCCCCCHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHH
SLNADRDFLKKGGVFTDDMIDGYVALKWEEVYNLEHAPHPIEYKMYYSV
HCCCCHHHHHHCCCCCHHHHCCEEEEEEHHHHCCCCCCCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2878685 [H]