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The map label for this gene is ppiD [H]

Identifier: 83593225

GI number: 83593225

Start: 2189361

End: 2191259

Strand: Direct

Name: ppiD [H]

Synonym: Rru_A1890

Alternate gene names: 83593225

Gene position: 2189361-2191259 (Clockwise)

Preceding gene: 83593219

Following gene: 83593226

Centisome position: 50.3

GC content: 69.14

Gene sequence:

>1899_bases
ATGCTCGACGCCCTGCGCAGAGGTTCCAAGTCCTGGCTCGCCAAAAGTCTTCTCGGGTTACTCGTCCTCAGCTTCGGCGT
GTGGGGCGTCGCCGATTACATGGTTCGCGGTGGCGGTCCAAAGCCGGCGATCACGGTTGGAGGGCAGAGCTTCGGCGCCG
GCTATGTGCGCAATCAGTTCTCCGAGGATCTGGGCCGCCTGCGCCGCCAGGGCATCGAACTTGATGCCGAACAGGCGATC
GCCATGGGCCTGCTCGGTCAGACCGTCCAGACCATCGTTCAAGGCGCCGTGCTTGACGAAAGCGGCCGCCGGCTTGGCCT
TGTCGCCAGCGACGACGCCTTGCGCTCGGCCATCCAGAACGATCCTTTGTTCAAGGGCGCCGACGGCCGCTTCGATCGCG
ACCGCCTGAGCCGCATCCTCGCGGCCAATAATCTGACCGAGGCCGGCTATATCGATCTGCGCCGCCGCGACATGATCCGC
GAAGCCCTGGTCGAGCCGGTGGTCAGCGCCGTGGGCGTTCCCGGGCCGATCGTCGATGTGCTGGCCGCCCATGCCTCCGA
ACGCCGCGTCGCCCAGGTCCTGACCGTCGCCAAGGCCGCCCTGCCGGCGCCGACGACGAAGCCGACCGAAGAGGCGCTGG
AAAAGGTCCGCCAGGAGAACCTTGATCGCTTCACCGCCCCGGAATATCGGACGGCCAAGGCCCTGCTGCTGACCCGCGAC
GCCGTGGCCGGTTCGATCACCGTCGCCGACGAGGCGATCGCCCAGTATTACGAGGCCCATGGCGACGAATTCGTTCAGCC
GGCCTCGCGCCGGGTCACCCAGGCGCTGTTTTCCAGCCGCGAGCAGGCCGACTCCGCCCTCGTCCTGATCCGCAGTTCCT
CGGCCAGCCTTGACGAGGCGTCGCGCAAGATCACCGGAAGCGGCGCCATCGACATGGGCAACGTCACCGACAGCTCGCTG
CCCGCCCCCCTGCCCGCCACCATCGCCGCCCAGGACGTCGGCGTGGTTGGCGAACCGGCGCAAAGCCCCCTTGGCTGGCA
TCTGTTCCTGGTGACCGCCGCCACCCCGGAAACCACCAAGCCTTTGGCCGAGGTCGCCCCGCAGATCCGCAAGACCCTGG
CCAGCGATCAGGCGGTGGATTCGCTCTATGCCCTGTCGACCCAGGTCGAGGACCTGCTGGCCGGCGGCGCCGGCATCGAC
GAGGTGGCGACCCAGGTCGGACTGCCGTTGTTGGCCTTCAGCGTCGACAGCCAGGGCAATTCCCAAGACGGCACCCCGGC
CAAGGGCCTGCCCAGCGACGGCGCCTTCCTCAAGACCCTGTTCGGTCTGGGCGAGGGCGAGGTCAGCCCGATGATCGACT
ACGAGGGCGGCTTCTTCATCCAGCGCCTGGAAACCATCACCCCCCGCGCCCCCCGGCCGCTTGACGCGGTGCGGGCCGAG
GTTGTCGCCCTGTGGCAGGACCAGGAACAGACCGCCACCGCCGGCCGCCTTGCCGAGGGCCTGTTGTCGCGGGCCAAGGC
CGGCGCCTCGTTCGAGGATCTGGCCGCCGCCGAGCCGGCAAGCCGCCTGTCGACCACCCCGCCGGTCACCCGGGACGGCC
GGTCCGATGGCGCGGCCGAGGCCGACCCGCTTCCCGGCGCCCTGGTTCAGGCCATGTTCGCCGCCCGTCAGGGGGACGTG
GTGCGCGCCGATGGCTCCGATGGCGTCTCGCTGCTGCGCGTCCTTGAGATCCGCCAGCCCTCCGCCGAAATCGCCGCCCG
CGAGCGCGCCAGCGTCGAACAAAGCCTGCGTCAGGCCTATTCCGCCGATGTGGCCAACGGCTATTCCGCCGCCCTTGGCG
ACACGGTCGGGGTCACCGTCGATCAGGGCGTGGTGCTTGACGCCGTCAAAACGAACTGA

Upstream 100 bases:

>100_bases
CTCGCCCCGGCTAGCGGCCCACTCGGGCGCCAGCCTTGGCGCGCGGGCCTTGCCGAGGCCGCTCCCGTCCTTTTTTCAAA
CTGCACAACGGTCCGCCCCC

Downstream 100 bases:

>100_bases
TCACCGCCCGCGCCAAAGGGGGTGCCTTTTGGCGCGGGTTTTCGCCTTCCAAGCCTAACGCGCAACCCCCAAAACCGCCG
TCCCGATCCATCCTCCTTGC

Product: hypothetical protein

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 632; Mature: 632

Protein sequence:

>632_residues
MLDALRRGSKSWLAKSLLGLLVLSFGVWGVADYMVRGGGPKPAITVGGQSFGAGYVRNQFSEDLGRLRRQGIELDAEQAI
AMGLLGQTVQTIVQGAVLDESGRRLGLVASDDALRSAIQNDPLFKGADGRFDRDRLSRILAANNLTEAGYIDLRRRDMIR
EALVEPVVSAVGVPGPIVDVLAAHASERRVAQVLTVAKAALPAPTTKPTEEALEKVRQENLDRFTAPEYRTAKALLLTRD
AVAGSITVADEAIAQYYEAHGDEFVQPASRRVTQALFSSREQADSALVLIRSSSASLDEASRKITGSGAIDMGNVTDSSL
PAPLPATIAAQDVGVVGEPAQSPLGWHLFLVTAATPETTKPLAEVAPQIRKTLASDQAVDSLYALSTQVEDLLAGGAGID
EVATQVGLPLLAFSVDSQGNSQDGTPAKGLPSDGAFLKTLFGLGEGEVSPMIDYEGGFFIQRLETITPRAPRPLDAVRAE
VVALWQDQEQTATAGRLAEGLLSRAKAGASFEDLAAAEPASRLSTTPPVTRDGRSDGAAEADPLPGALVQAMFAARQGDV
VRADGSDGVSLLRVLEIRQPSAEIAARERASVEQSLRQAYSADVANGYSAALGDTVGVTVDQGVVLDAVKTN

Sequences:

>Translated_632_residues
MLDALRRGSKSWLAKSLLGLLVLSFGVWGVADYMVRGGGPKPAITVGGQSFGAGYVRNQFSEDLGRLRRQGIELDAEQAI
AMGLLGQTVQTIVQGAVLDESGRRLGLVASDDALRSAIQNDPLFKGADGRFDRDRLSRILAANNLTEAGYIDLRRRDMIR
EALVEPVVSAVGVPGPIVDVLAAHASERRVAQVLTVAKAALPAPTTKPTEEALEKVRQENLDRFTAPEYRTAKALLLTRD
AVAGSITVADEAIAQYYEAHGDEFVQPASRRVTQALFSSREQADSALVLIRSSSASLDEASRKITGSGAIDMGNVTDSSL
PAPLPATIAAQDVGVVGEPAQSPLGWHLFLVTAATPETTKPLAEVAPQIRKTLASDQAVDSLYALSTQVEDLLAGGAGID
EVATQVGLPLLAFSVDSQGNSQDGTPAKGLPSDGAFLKTLFGLGEGEVSPMIDYEGGFFIQRLETITPRAPRPLDAVRAE
VVALWQDQEQTATAGRLAEGLLSRAKAGASFEDLAAAEPASRLSTTPPVTRDGRSDGAAEADPLPGALVQAMFAARQGDV
VRADGSDGVSLLRVLEIRQPSAEIAARERASVEQSLRQAYSADVANGYSAALGDTVGVTVDQGVVLDAVKTN
>Mature_632_residues
MLDALRRGSKSWLAKSLLGLLVLSFGVWGVADYMVRGGGPKPAITVGGQSFGAGYVRNQFSEDLGRLRRQGIELDAEQAI
AMGLLGQTVQTIVQGAVLDESGRRLGLVASDDALRSAIQNDPLFKGADGRFDRDRLSRILAANNLTEAGYIDLRRRDMIR
EALVEPVVSAVGVPGPIVDVLAAHASERRVAQVLTVAKAALPAPTTKPTEEALEKVRQENLDRFTAPEYRTAKALLLTRD
AVAGSITVADEAIAQYYEAHGDEFVQPASRRVTQALFSSREQADSALVLIRSSSASLDEASRKITGSGAIDMGNVTDSSL
PAPLPATIAAQDVGVVGEPAQSPLGWHLFLVTAATPETTKPLAEVAPQIRKTLASDQAVDSLYALSTQVEDLLAGGAGID
EVATQVGLPLLAFSVDSQGNSQDGTPAKGLPSDGAFLKTLFGLGEGEVSPMIDYEGGFFIQRLETITPRAPRPLDAVRAE
VVALWQDQEQTATAGRLAEGLLSRAKAGASFEDLAAAEPASRLSTTPPVTRDGRSDGAAEADPLPGALVQAMFAARQGDV
VRADGSDGVSLLRVLEIRQPSAEIAARERASVEQSLRQAYSADVANGYSAALGDTVGVTVDQGVVLDAVKTN

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=570, Percent_Identity=28.0701754385965, Blast_Score=153, Evalue=3e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 66419; Mature: 66419

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDALRRGSKSWLAKSLLGLLVLSFGVWGVADYMVRGGGPKPAITVGGQSFGAGYVRNQF
CCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHH
SEDLGRLRRQGIELDAEQAIAMGLLGQTVQTIVQGAVLDESGRRLGLVASDDALRSAIQN
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHC
DPLFKGADGRFDRDRLSRILAANNLTEAGYIDLRRRDMIREALVEPVVSAVGVPGPIVDV
CCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
LAAHASERRVAQVLTVAKAALPAPTTKPTEEALEKVRQENLDRFTAPEYRTAKALLLTRD
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHEEHH
AVAGSITVADEAIAQYYEAHGDEFVQPASRRVTQALFSSREQADSALVLIRSSSASLDEA
HHCCCEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHH
SRKITGSGAIDMGNVTDSSLPAPLPATIAAQDVGVVGEPAQSPLGWHLFLVTAATPETTK
HHHCCCCCCEEECCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCCCC
PLAEVAPQIRKTLASDQAVDSLYALSTQVEDLLAGGAGIDEVATQVGLPLLAFSVDSQGN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCEEEEEECCCCC
SQDGTPAKGLPSDGAFLKTLFGLGEGEVSPMIDYEGGFFIQRLETITPRAPRPLDAVRAE
CCCCCCCCCCCCCCHHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHCCCCCCCHHHHHHH
VVALWQDQEQTATAGRLAEGLLSRAKAGASFEDLAAAEPASRLSTTPPVTRDGRSDGAAE
HHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHCCCCCCCCCCCCCCCCCC
ADPLPGALVQAMFAARQGDVVRADGSDGVSLLRVLEIRQPSAEIAARERASVEQSLRQAY
CCCCCHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
SADVANGYSAALGDTVGVTVDQGVVLDAVKTN
HHHHCCCCHHHCCCCCCEEECCCEEEEEECCC
>Mature Secondary Structure
MLDALRRGSKSWLAKSLLGLLVLSFGVWGVADYMVRGGGPKPAITVGGQSFGAGYVRNQF
CCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHH
SEDLGRLRRQGIELDAEQAIAMGLLGQTVQTIVQGAVLDESGRRLGLVASDDALRSAIQN
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHC
DPLFKGADGRFDRDRLSRILAANNLTEAGYIDLRRRDMIREALVEPVVSAVGVPGPIVDV
CCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
LAAHASERRVAQVLTVAKAALPAPTTKPTEEALEKVRQENLDRFTAPEYRTAKALLLTRD
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHEEHH
AVAGSITVADEAIAQYYEAHGDEFVQPASRRVTQALFSSREQADSALVLIRSSSASLDEA
HHCCCEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHH
SRKITGSGAIDMGNVTDSSLPAPLPATIAAQDVGVVGEPAQSPLGWHLFLVTAATPETTK
HHHCCCCCCEEECCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCCCC
PLAEVAPQIRKTLASDQAVDSLYALSTQVEDLLAGGAGIDEVATQVGLPLLAFSVDSQGN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCEEEEEECCCCC
SQDGTPAKGLPSDGAFLKTLFGLGEGEVSPMIDYEGGFFIQRLETITPRAPRPLDAVRAE
CCCCCCCCCCCCCCHHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHCCCCCCCHHHHHHH
VVALWQDQEQTATAGRLAEGLLSRAKAGASFEDLAAAEPASRLSTTPPVTRDGRSDGAAE
HHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHCCCCCCCCCCCCCCCCCC
ADPLPGALVQAMFAARQGDVVRADGSDGVSLLRVLEIRQPSAEIAARERASVEQSLRQAY
CCCCCHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
SADVANGYSAALGDTVGVTVDQGVVLDAVKTN
HHHHCCCCHHHCCCCCCEEECCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]