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The map label for this gene is luxQ [H]

Identifier: 83593219

GI number: 83593219

Start: 2182500

End: 2183540

Strand: Direct

Name: luxQ [H]

Synonym: Rru_A1884

Alternate gene names: 83593219

Gene position: 2182500-2183540 (Clockwise)

Preceding gene: 83593218

Following gene: 83593225

Centisome position: 50.14

GC content: 64.27

Gene sequence:

>1041_bases
ATGGAGGGCGCAGAGGCCATGAGACCGCGGCAACGGTGGATTCCCGTGGTCGTCTTCCTCACCTTATCGGTCGTTCTGAC
CGCCGGCTTGGTGAGCGTTGATGCGTTCGATCTGTTTTATGATTTTTCGCGCGCCCACGAGAGCTGGGAAGCCGACGAAA
TCGCCCTGGCGCTGTTTGCGGCGATCTTCGGCGGTTTCATCGCCTTCTTTTTTGAAGTCTGGAGGGTCAACCGCTCGTTG
ACACTGAGTCTGGCCGCCCTTGAGGAGGCCAAGCGCGAGGCCGAGACGGCGCGCCACGAGGCCGAGGCGGCCCATGCCGC
CAAAAACCACTTCCTATCCCACCTCAATCAGGAACTGCGCACGCCGCTCAACGCCATCTCGGGGTATGCCGAGAAAATCG
CCCAATTGGCCGAGACCCGCCCGCTTCCCGAGCAGGTCACCCAGGGCGTCGGCCAAATCCGCCGGGCCAGCGACGAGTTG
CGCCAGTTGATCGACGAGTTGCTCGACCTGTCGGCGGTGGGCGACGGCACGCTGAGCCTGGATTTGCGCCCGGTCGACAT
CCTCGGCTTTTTCGCCCTCTGCGCCCGCGACCTGCAAACCCTGTTTTCGCGCCGCCATTCCACCCTCGACCTTGATCTGG
CGGGCATCGGTGGCAAGGCGATGATCGACGAGGCGCGCTTGAAGCAGATCCTTTATGCGGTTCTGATCAGCGCCATTCGC
CAGACCCCGGAAGGGGTGGTCGACCTCAGCGCCTCGACCACCGATCAGCCAAGCCCAGGCCTGTCGAAAAGCCAAAGGGA
ACCGCGCGTTCTCCACGTCACCGTCACCAGCGATTCCCTCAGCCGCTCGCTCACCCGCATCGCCGATCCCTTCGCCCCTT
TTCAAAGCGGCGGCGACGAGTCCATGGGGATCGGCTTGGGGTTGACGCTCAGCCGCTCGCTCGCCCAACGCATGGGCGGC
GATCTTGTCGTCGCCCGGGTCAGCGGCGGCCGCAACGGCTATCACATCCGCATCCCCTTGCCGCCGGCCGTCGACGGATA
A

Upstream 100 bases:

>100_bases
GACCTTTCTTCCACGATACTAACGTCGATTCCATCAAGACCGGCGGGGCTTGCGTCCCCGTCGCGACGGAAGCCGGGAGA
TCAGGGATCAGAGGTGGGGA

Downstream 100 bases:

>100_bases
AAAAGGCCGCCATCCCAAGGGAACGGCGGCCCGTTTTTTGTCCAATCAGGCCAACAACGGCCGAAGACCGATTAACCGCG
CAGGATGCTGGCGCCGGCGT

Product: periplasmic sensor Signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MEGAEAMRPRQRWIPVVVFLTLSVVLTAGLVSVDAFDLFYDFSRAHESWEADEIALALFAAIFGGFIAFFFEVWRVNRSL
TLSLAALEEAKREAETARHEAEAAHAAKNHFLSHLNQELRTPLNAISGYAEKIAQLAETRPLPEQVTQGVGQIRRASDEL
RQLIDELLDLSAVGDGTLSLDLRPVDILGFFALCARDLQTLFSRRHSTLDLDLAGIGGKAMIDEARLKQILYAVLISAIR
QTPEGVVDLSASTTDQPSPGLSKSQREPRVLHVTVTSDSLSRSLTRIADPFAPFQSGGDESMGIGLGLTLSRSLAQRMGG
DLVVARVSGGRNGYHIRIPLPPAVDG

Sequences:

>Translated_346_residues
MEGAEAMRPRQRWIPVVVFLTLSVVLTAGLVSVDAFDLFYDFSRAHESWEADEIALALFAAIFGGFIAFFFEVWRVNRSL
TLSLAALEEAKREAETARHEAEAAHAAKNHFLSHLNQELRTPLNAISGYAEKIAQLAETRPLPEQVTQGVGQIRRASDEL
RQLIDELLDLSAVGDGTLSLDLRPVDILGFFALCARDLQTLFSRRHSTLDLDLAGIGGKAMIDEARLKQILYAVLISAIR
QTPEGVVDLSASTTDQPSPGLSKSQREPRVLHVTVTSDSLSRSLTRIADPFAPFQSGGDESMGIGLGLTLSRSLAQRMGG
DLVVARVSGGRNGYHIRIPLPPAVDG
>Mature_346_residues
MEGAEAMRPRQRWIPVVVFLTLSVVLTAGLVSVDAFDLFYDFSRAHESWEADEIALALFAAIFGGFIAFFFEVWRVNRSL
TLSLAALEEAKREAETARHEAEAAHAAKNHFLSHLNQELRTPLNAISGYAEKIAQLAETRPLPEQVTQGVGQIRRASDEL
RQLIDELLDLSAVGDGTLSLDLRPVDILGFFALCARDLQTLFSRRHSTLDLDLAGIGGKAMIDEARLKQILYAVLISAIR
QTPEGVVDLSASTTDQPSPGLSKSQREPRVLHVTVTSDSLSRSLTRIADPFAPFQSGGDESMGIGLGLTLSRSLAQRMGG
DLVVARVSGGRNGYHIRIPLPPAVDG

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=279, Percent_Identity=26.8817204301075, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI48994928, Length=250, Percent_Identity=26.8, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI87081816, Length=267, Percent_Identity=28.8389513108614, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788713, Length=251, Percent_Identity=24.3027888446215, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1789149, Length=276, Percent_Identity=25.7246376811594, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 37667; Mature: 37667

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEGAEAMRPRQRWIPVVVFLTLSVVLTAGLVSVDAFDLFYDFSRAHESWEADEIALALFA
CCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
AIFGGFIAFFFEVWRVNRSLTLSLAALEEAKREAETARHEAEAAHAAKNHFLSHLNQELR
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TPLNAISGYAEKIAQLAETRPLPEQVTQGVGQIRRASDELRQLIDELLDLSAVGDGTLSL
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
DLRPVDILGFFALCARDLQTLFSRRHSTLDLDLAGIGGKAMIDEARLKQILYAVLISAIR
ECCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
QTPEGVVDLSASTTDQPSPGLSKSQREPRVLHVTVTSDSLSRSLTRIADPFAPFQSGGDE
CCCCCEEECCCCCCCCCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHCCCCHHHCCCCC
SMGIGLGLTLSRSLAQRMGGDLVVARVSGGRNGYHIRIPLPPAVDG
CCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEECCCCCCC
>Mature Secondary Structure
MEGAEAMRPRQRWIPVVVFLTLSVVLTAGLVSVDAFDLFYDFSRAHESWEADEIALALFA
CCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
AIFGGFIAFFFEVWRVNRSLTLSLAALEEAKREAETARHEAEAAHAAKNHFLSHLNQELR
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TPLNAISGYAEKIAQLAETRPLPEQVTQGVGQIRRASDELRQLIDELLDLSAVGDGTLSL
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
DLRPVDILGFFALCARDLQTLFSRRHSTLDLDLAGIGGKAMIDEARLKQILYAVLISAIR
ECCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
QTPEGVVDLSASTTDQPSPGLSKSQREPRVLHVTVTSDSLSRSLTRIADPFAPFQSGGDE
CCCCCEEECCCCCCCCCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHCCCCHHHCCCCC
SMGIGLGLTLSRSLAQRMGGDLVVARVSGGRNGYHIRIPLPPAVDG
CCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]