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The map label for this gene is corA [H]

Identifier: 83593218

GI number: 83593218

Start: 2181360

End: 2182355

Strand: Direct

Name: corA [H]

Synonym: Rru_A1883

Alternate gene names: 83593218

Gene position: 2181360-2182355 (Clockwise)

Preceding gene: 83593210

Following gene: 83593219

Centisome position: 50.11

GC content: 60.54

Gene sequence:

>996_bases
ATGGTCAAGGGGCTTCCGATGATCCTGGGATACGCCGAGGAAAACGGCCGGCTACGGCGCCTGCCAGTGCCACTCGATGA
AACCGAACGGGTTATTTGGTACGACCTTTTCTGCCCCACCCCGCGCGAGGCCGCCCAGGTCGCCTCGGTGCTCGGCATCG
AGATCCCGACGCGCGAGGAGATGGAGGAGATCGAGATTTCAAGCCGGCTTTATCAGGAAGACGACGCGATCTTCATGACC
GCCACCTTGCTCTCGCGCACCGATACCGATCAGCCCCAATCCTCGCCCGTCACCTTCATTCTGGCCGGCGCCCGGCTGGT
CACCATTCGCTACGAGGAACCCCGGGCCTTCCAGGCTTTCCCGACGCGGGCCGAAAAAGCCGGGCTCGGCTGTTTCAGCG
GCGAAAAGACCCTGCTCGCCCTGCTCGAGGCCGTCGTCGACCGCCTGGCCGATGTCCTTGAACGCGACGCCCGGGAAATC
GACCGCCTGTCGCAAAGCATCTTTTCCCACGACTCGTCGGGATCACGGGATTCGCGCGACAAGGACTTCCAGAAGATCCT
GAAACTGATCGGCCGCAAGGGCGATCTGACCAGCGACATCCGCGAAAGCATGGTCAGCCTGCAACGGGTTTTCGTCTATC
TCACCCAGATCGCCACCGAACGCAAAACCGGCAAGGACAGCCGGACCCGCTTGCGCACCCTCCACCGCGACGCCCAGTCG
CTGACCGATCACGCCACCTTCTTGTCGAGCAAGATCACTTTCCTGCTTGATGCGACGCTGGGCATGATCAATATCGAACA
GAACGCCATCATCAAACTCTTCTCGGTGGTCGCCGTCATCTTCCTGCCGCCAACCCTGGTCGCCAGCATTTATGGAATGA
ATTTCCGCTATATGCCCGAACTTGAATGGCCTTTCGGCTATCCTCTGGCCATCGCCCTGATGCTCGCCTCGGCCATCATT
CCTTACCGGTTGTTCAAACGATGGGGTTGGCTCTGA

Upstream 100 bases:

>100_bases
TTCGTCTGGCGAAGTCCTTATGCCCGTCCGCACCAACCCATCCCGGCGCGTCCGCCCTTCGCCCCCCGGGCAGGATCAGG
CGCGCCACCCTCCTTTCAAG

Downstream 100 bases:

>100_bases
GGAACGACACCCTGCCTTTTGATCTAGCTTTCGCCTAGCCAGTAGACCTTTCTTCCACGATACTAACGTCGATTCCATCA
AGACCGGCGGGGCTTGCGTC

Product: magnesium/cobalt transporter CorA

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MVKGLPMILGYAEENGRLRRLPVPLDETERVIWYDLFCPTPREAAQVASVLGIEIPTREEMEEIEISSRLYQEDDAIFMT
ATLLSRTDTDQPQSSPVTFILAGARLVTIRYEEPRAFQAFPTRAEKAGLGCFSGEKTLLALLEAVVDRLADVLERDAREI
DRLSQSIFSHDSSGSRDSRDKDFQKILKLIGRKGDLTSDIRESMVSLQRVFVYLTQIATERKTGKDSRTRLRTLHRDAQS
LTDHATFLSSKITFLLDATLGMINIEQNAIIKLFSVVAVIFLPPTLVASIYGMNFRYMPELEWPFGYPLAIALMLASAII
PYRLFKRWGWL

Sequences:

>Translated_331_residues
MVKGLPMILGYAEENGRLRRLPVPLDETERVIWYDLFCPTPREAAQVASVLGIEIPTREEMEEIEISSRLYQEDDAIFMT
ATLLSRTDTDQPQSSPVTFILAGARLVTIRYEEPRAFQAFPTRAEKAGLGCFSGEKTLLALLEAVVDRLADVLERDAREI
DRLSQSIFSHDSSGSRDSRDKDFQKILKLIGRKGDLTSDIRESMVSLQRVFVYLTQIATERKTGKDSRTRLRTLHRDAQS
LTDHATFLSSKITFLLDATLGMINIEQNAIIKLFSVVAVIFLPPTLVASIYGMNFRYMPELEWPFGYPLAIALMLASAII
PYRLFKRWGWL
>Mature_331_residues
MVKGLPMILGYAEENGRLRRLPVPLDETERVIWYDLFCPTPREAAQVASVLGIEIPTREEMEEIEISSRLYQEDDAIFMT
ATLLSRTDTDQPQSSPVTFILAGARLVTIRYEEPRAFQAFPTRAEKAGLGCFSGEKTLLALLEAVVDRLADVLERDAREI
DRLSQSIFSHDSSGSRDSRDKDFQKILKLIGRKGDLTSDIRESMVSLQRVFVYLTQIATERKTGKDSRTRLRTLHRDAQS
LTDHATFLSSKITFLLDATLGMINIEQNAIIKLFSVVAVIFLPPTLVASIYGMNFRYMPELEWPFGYPLAIALMLASAII
PYRLFKRWGWL

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI2367297, Length=328, Percent_Identity=36.5853658536585, Blast_Score=199, Evalue=2e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 37573; Mature: 37573

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: PS00041 HTH_ARAC_FAMILY_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKGLPMILGYAEENGRLRRLPVPLDETERVIWYDLFCPTPREAAQVASVLGIEIPTREE
CCCCCCEEEEEECCCCCEEECCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCCHHH
MEEIEISSRLYQEDDAIFMTATLLSRTDTDQPQSSPVTFILAGARLVTIRYEEPRAFQAF
HHHHHHHHHHHHCCCCEEEHHHHHHCCCCCCCCCCCEEEEEECCEEEEEEECCCCCHHHC
PTRAEKAGLGCFSGEKTLLALLEAVVDRLADVLERDAREIDRLSQSIFSHDSSGSRDSRD
CCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCH
KDFQKILKLIGRKGDLTSDIRESMVSLQRVFVYLTQIATERKTGKDSRTRLRTLHRDAQS
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
LTDHATFLSSKITFLLDATLGMINIEQNAIIKLFSVVAVIFLPPTLVASIYGMNFRYMPE
HHHHHHHHHHHHHHHHHHHHCEEECCHHHHHHHHHHHHHHHHCHHHHHHHHCCCCEECCC
LEWPFGYPLAIALMLASAIIPYRLFKRWGWL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVKGLPMILGYAEENGRLRRLPVPLDETERVIWYDLFCPTPREAAQVASVLGIEIPTREE
CCCCCCEEEEEECCCCCEEECCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCCHHH
MEEIEISSRLYQEDDAIFMTATLLSRTDTDQPQSSPVTFILAGARLVTIRYEEPRAFQAF
HHHHHHHHHHHHCCCCEEEHHHHHHCCCCCCCCCCCEEEEEECCEEEEEEECCCCCHHHC
PTRAEKAGLGCFSGEKTLLALLEAVVDRLADVLERDAREIDRLSQSIFSHDSSGSRDSRD
CCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCH
KDFQKILKLIGRKGDLTSDIRESMVSLQRVFVYLTQIATERKTGKDSRTRLRTLHRDAQS
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
LTDHATFLSSKITFLLDATLGMINIEQNAIIKLFSVVAVIFLPPTLVASIYGMNFRYMPE
HHHHHHHHHHHHHHHHHHHHCEEECCHHHHHHHHHHHHHHHHCHHHHHHHHCCCCEECCC
LEWPFGYPLAIALMLASAIIPYRLFKRWGWL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]