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The map label for this gene is cph1 [H]

Identifier: 83593210

GI number: 83593210

Start: 2172205

End: 2173710

Strand: Direct

Name: cph1 [H]

Synonym: Rru_A1875

Alternate gene names: 83593210

Gene position: 2172205-2173710 (Clockwise)

Preceding gene: 83593207

Following gene: 83593218

Centisome position: 49.9

GC content: 67.26

Gene sequence:

>1506_bases
ATGTTGTTCGCTCCACCCCGCGGCACCAACGACCCCGAGGATTTTCCCGGGGAAGGCAGCGATCCCCGGACGCTCTTTCC
CGCTCCGCTCTCGGCCCGGCTGGTTCTGCTCGGGGGCCTGTTCACCCTGTTCAGCACGGTGGCCATCACGCTTTGGCTGA
TCGGACTGGCCGCCCGCTACCCCGATCACGCCCTTTTGGCGCCGGTGGCCGGCGGCGGCGCGGTCATCGTCACCCTGACC
GGGGTCTGCCTGATCGCCTTCCTTTTCCGCGAACGCCGCCATCTCGCCGCCGAGCGCCGGCTGGCGCTCAGCGAGGCCCG
GTTGCAGACGGCCCTGGAAAACACCGGGGACGGCATCTGGGATTGGCAGATCCCCGGCGATGTCGTTCATCTCAACGGCG
CGCTGATCGCCCGCCTGGGCTTTCCCGTCGACACCCCCTCGCCCACCGCCACCTGGGAAACGATGATCCATCCCGAGGAT
CGCCCGGCCACCCTTGCCGCCTTTCACGACCATCTCGCCGGCAAAACCCCGAGCTATCATGCGCGCTATCGCTGGAAGCT
GCCCGATGGCGTGATGATCTGGGTAGAGGCCAAGGGCCGGGTCGTCACCCGCGACCGCTCGGGCAAGCCCTTGCGCATGA
CCGGAACGCTGAGCGACGCCACCCCTCAGGTCGAAGCCGAAGAGCTGATGCGCGAGAAATCGCGGCGGCTCGAGGAGTCC
AACCGCGATCTCGAACAATTCGCCTATGTGGCCTCCCACGACCTGCAAGAGCCGCTGCGCATGGTCTCGTCCTATCTGGG
ACTGCTGCGCCGGCGCCACGGCGACCAGCTCGCCCCCGAGGCGCTGGAGTTCATGTCCTATGCCGAAGACGGCGCCAAGC
GCATGTCACGGCTGATCCTCGACCTTTTGGAGTATTCGCGCGTCACCACCCGGGGGGAGCCCCCGGAAACGGTCGCCCTG
GCCGAGGTGATCGACGAAGCGCGGTCCAACCTGCGCATGATCATCGACGAGACGGCGGCGCGGATCGACCTGCTGGGCTG
CGATCGTACGGTTTTGGCCGATCGCGGACAGGTGGTCCGCGTCTTTCAGAATCTGATCGGCAATGCCCTGAAATACCGTT
CGCCCGACCGGCCGCCGATAATCACCCTGCGCTGTGGCGAAGACGAGGGGTGGGTCAACGTCAGCGTGGCCGATAACGGC
ATCGGCTTCAGTCCCGAGCACGCCGAACGGATCTTCATCATCTTCCAACGCCTGCATGGCCCAAAAGCCTATGAGGGCAC
CGGCATCGGCCTGTCCATCTGCAAACGCATCATCGAGCGCCACGGCGGCACCATCGAAGCCCAGGGAACCCCGGGCGAAG
GGGCCCTCTTCCGCTTCACTTTGCCCCGCGCCCCCGGACCCTCCCGGTCGACGGGCGGCGCCCCCGACAACCAAGACCGT
CGCCGCCGCGACCAAGGCCGGGGCGCTGACGGGAGGGGGCGCGATCAGGGCCGCTTGGCGCCGTAA

Upstream 100 bases:

>100_bases
CTGTTATGATAAACCATCTGCGGATCCAGCCTCTGCCGTTTCCCATTCCCCCCGGAATGGGGCCGAGCGGAGGGAACGCA
AGGAGGGTATCGGTTCTTCC

Downstream 100 bases:

>100_bases
AGCTGTTCGGCGCGGCGCTCGAACGAGGAGACCATCAGGCGGACCGCCTCGCTGAACAAGGCGCCGATGATCTTTTGCAA
AAGCGGCGACTTGAATTCGA

Product: multi-sensor Signal transduction histidine kinase

Products: NA

Alternate protein names: Bacteriophytochrome cph1; Light-regulated histidine kinase 1 [H]

Number of amino acids: Translated: 501; Mature: 501

Protein sequence:

>501_residues
MLFAPPRGTNDPEDFPGEGSDPRTLFPAPLSARLVLLGGLFTLFSTVAITLWLIGLAARYPDHALLAPVAGGGAVIVTLT
GVCLIAFLFRERRHLAAERRLALSEARLQTALENTGDGIWDWQIPGDVVHLNGALIARLGFPVDTPSPTATWETMIHPED
RPATLAAFHDHLAGKTPSYHARYRWKLPDGVMIWVEAKGRVVTRDRSGKPLRMTGTLSDATPQVEAEELMREKSRRLEES
NRDLEQFAYVASHDLQEPLRMVSSYLGLLRRRHGDQLAPEALEFMSYAEDGAKRMSRLILDLLEYSRVTTRGEPPETVAL
AEVIDEARSNLRMIIDETAARIDLLGCDRTVLADRGQVVRVFQNLIGNALKYRSPDRPPIITLRCGEDEGWVNVSVADNG
IGFSPEHAERIFIIFQRLHGPKAYEGTGIGLSICKRIIERHGGTIEAQGTPGEGALFRFTLPRAPGPSRSTGGAPDNQDR
RRRDQGRGADGRGRDQGRLAP

Sequences:

>Translated_501_residues
MLFAPPRGTNDPEDFPGEGSDPRTLFPAPLSARLVLLGGLFTLFSTVAITLWLIGLAARYPDHALLAPVAGGGAVIVTLT
GVCLIAFLFRERRHLAAERRLALSEARLQTALENTGDGIWDWQIPGDVVHLNGALIARLGFPVDTPSPTATWETMIHPED
RPATLAAFHDHLAGKTPSYHARYRWKLPDGVMIWVEAKGRVVTRDRSGKPLRMTGTLSDATPQVEAEELMREKSRRLEES
NRDLEQFAYVASHDLQEPLRMVSSYLGLLRRRHGDQLAPEALEFMSYAEDGAKRMSRLILDLLEYSRVTTRGEPPETVAL
AEVIDEARSNLRMIIDETAARIDLLGCDRTVLADRGQVVRVFQNLIGNALKYRSPDRPPIITLRCGEDEGWVNVSVADNG
IGFSPEHAERIFIIFQRLHGPKAYEGTGIGLSICKRIIERHGGTIEAQGTPGEGALFRFTLPRAPGPSRSTGGAPDNQDR
RRRDQGRGADGRGRDQGRLAP
>Mature_501_residues
MLFAPPRGTNDPEDFPGEGSDPRTLFPAPLSARLVLLGGLFTLFSTVAITLWLIGLAARYPDHALLAPVAGGGAVIVTLT
GVCLIAFLFRERRHLAAERRLALSEARLQTALENTGDGIWDWQIPGDVVHLNGALIARLGFPVDTPSPTATWETMIHPED
RPATLAAFHDHLAGKTPSYHARYRWKLPDGVMIWVEAKGRVVTRDRSGKPLRMTGTLSDATPQVEAEELMREKSRRLEES
NRDLEQFAYVASHDLQEPLRMVSSYLGLLRRRHGDQLAPEALEFMSYAEDGAKRMSRLILDLLEYSRVTTRGEPPETVAL
AEVIDEARSNLRMIIDETAARIDLLGCDRTVLADRGQVVRVFQNLIGNALKYRSPDRPPIITLRCGEDEGWVNVSVADNG
IGFSPEHAERIFIIFQRLHGPKAYEGTGIGLSICKRIIERHGGTIEAQGTPGEGALFRFTLPRAPGPSRSTGGAPDNQDR
RRRDQGRGADGRGRDQGRLAP

Specific function: Regulatory photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region. Has also a slight blue shift

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786912, Length=241, Percent_Identity=31.1203319502075, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI145693157, Length=256, Percent_Identity=25, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788549, Length=250, Percent_Identity=28, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI48994928, Length=305, Percent_Identity=26.8852459016393, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1788713, Length=228, Percent_Identity=25, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1790346, Length=222, Percent_Identity=28.3783783783784, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1790436, Length=242, Percent_Identity=26.4462809917355, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1789149, Length=265, Percent_Identity=23.3962264150943, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1786783, Length=256, Percent_Identity=25.78125, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788393, Length=234, Percent_Identity=26.9230769230769, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1786600, Length=241, Percent_Identity=27.3858921161826, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI87082128, Length=240, Percent_Identity=28.3333333333333, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR000014
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 55300; Mature: 55300

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFAPPRGTNDPEDFPGEGSDPRTLFPAPLSARLVLLGGLFTLFSTVAITLWLIGLAARY
CCCCCCCCCCCCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PDHALLAPVAGGGAVIVTLTGVCLIAFLFRERRHLAAERRLALSEARLQTALENTGDGIW
CCCEEEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
DWQIPGDVVHLNGALIARLGFPVDTPSPTATWETMIHPEDRPATLAAFHDHLAGKTPSYH
EECCCCCEEEECCEEEEEECCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCC
ARYRWKLPDGVMIWVEAKGRVVTRDRSGKPLRMTGTLSDATPQVEAEELMREKSRRLEES
CEEEEECCCCEEEEEECCCEEEEECCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHH
NRDLEQFAYVASHDLQEPLRMVSSYLGLLRRRHGDQLAPEALEFMSYAEDGAKRMSRLIL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
DLLEYSRVTTRGEPPETVALAEVIDEARSNLRMIIDETAARIDLLGCDRTVLADRGQVVR
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHEEHHHHHHHEEEEECCCCHHHHCCCHHHH
VFQNLIGNALKYRSPDRPPIITLRCGEDEGWVNVSVADNGIGFSPEHAERIFIIFQRLHG
HHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCC
PKAYEGTGIGLSICKRIIERHGGTIEAQGTPGEGALFRFTLPRAPGPSRSTGGAPDNQDR
CCCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHH
RRRDQGRGADGRGRDQGRLAP
HHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLFAPPRGTNDPEDFPGEGSDPRTLFPAPLSARLVLLGGLFTLFSTVAITLWLIGLAARY
CCCCCCCCCCCCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PDHALLAPVAGGGAVIVTLTGVCLIAFLFRERRHLAAERRLALSEARLQTALENTGDGIW
CCCEEEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
DWQIPGDVVHLNGALIARLGFPVDTPSPTATWETMIHPEDRPATLAAFHDHLAGKTPSYH
EECCCCCEEEECCEEEEEECCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCC
ARYRWKLPDGVMIWVEAKGRVVTRDRSGKPLRMTGTLSDATPQVEAEELMREKSRRLEES
CEEEEECCCCEEEEEECCCEEEEECCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHH
NRDLEQFAYVASHDLQEPLRMVSSYLGLLRRRHGDQLAPEALEFMSYAEDGAKRMSRLIL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
DLLEYSRVTTRGEPPETVALAEVIDEARSNLRMIIDETAARIDLLGCDRTVLADRGQVVR
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHEEHHHHHHHEEEEECCCCHHHHCCCHHHH
VFQNLIGNALKYRSPDRPPIITLRCGEDEGWVNVSVADNGIGFSPEHAERIFIIFQRLHG
HHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCC
PKAYEGTGIGLSICKRIIERHGGTIEAQGTPGEGALFRFTLPRAPGPSRSTGGAPDNQDR
CCCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHH
RRRDQGRGADGRGRDQGRLAP
HHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 9109482; 9278513; 10828948 [H]