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The map label for this gene is lepB [H]

Identifier: 83593188

GI number: 83593188

Start: 2151691

End: 2152428

Strand: Reverse

Name: lepB [H]

Synonym: Rru_A1853

Alternate gene names: 83593188

Gene position: 2152428-2151691 (Counterclockwise)

Preceding gene: 83593189

Following gene: 83593187

Centisome position: 49.45

GC content: 59.35

Gene sequence:

>738_bases
ATGAGCAGAAAAAAGGGCGGGGGCCTGGGCGAGACGATCAAAACGGTCGTCTATGCCTTTCTGATCGCCATCGTCATCAG
AACATTCGCCTACGAACCCTTTCGCATTCCCTCGGGGTCGATGATTCCGACCCTGCTGGTGGGCGATTATCTGTTCGTGT
CGAAATTCTCCTATGGCTATTCGCGCTTTTCCTTCCCGATGGGGATCATTCCCTTTAGCGGGCGGGTGTTGGGCGATGTG
CCCAAGCGCGGCGATGTCGTGGTCTTCAAGGAGCCCAACGATACCTCTGTCGATTTCATCAAGCGGGTGGTCGGACTGCC
CGGTGATCGGATCCAGGTGATCGACGGCATCTTGAACGTCAACGGCGAGCCGGTGCGCCGCGAGCGGACCGAGGACTTTG
TCCAGCGCGAAGCCGGCGGCAGCGTGCTGCGCCTGACCCAATATCAGGAAACCTTGCCCAACGGCGTGGTCCACCCCATT
CTCGAGATCCATGGCGATACCTATTTTCTCGATAACACCCGCGAGTTCCGGGTGCCCGAGGGCCATTATTTCATGATGGG
CGACAACCGCGACAGCAGCCAGGACAGCCGGGCGACGGTGGGCTTCGTGCCGGCCGAGAATCTGGTTGGACGGGCCGAGT
TCGTGTTCTTCTCGCACGATGGATCGGCGGCGATCTGGCAGGTCTGGAAATGGCCCTTCGCCATTCGCTGGGACCGCTTC
TTCCATTCGATCGATTAA

Upstream 100 bases:

>100_bases
CAGCCTTGACATTGGCCGGGCGCGGGGGCTTCATCTGGCGGCCGGACTCCGTCGAGGAGGCCGCGTTCAGCTTTATCCAA
TTGGTCCGAAAGATTTCCTC

Downstream 100 bases:

>100_bases
GGACGCCTGCGTGGTGGGATGGTTTGTTTTGTTGACGGGACGGCGTAAGGCCTGTCCCGTCTTTTGTCGGTTTTTCCGGG
TTTTGGAGGGTCCATGGCCC

Product: signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 245; Mature: 244

Protein sequence:

>245_residues
MSRKKGGGLGETIKTVVYAFLIAIVIRTFAYEPFRIPSGSMIPTLLVGDYLFVSKFSYGYSRFSFPMGIIPFSGRVLGDV
PKRGDVVVFKEPNDTSVDFIKRVVGLPGDRIQVIDGILNVNGEPVRRERTEDFVQREAGGSVLRLTQYQETLPNGVVHPI
LEIHGDTYFLDNTREFRVPEGHYFMMGDNRDSSQDSRATVGFVPAENLVGRAEFVFFSHDGSAAIWQVWKWPFAIRWDRF
FHSID

Sequences:

>Translated_245_residues
MSRKKGGGLGETIKTVVYAFLIAIVIRTFAYEPFRIPSGSMIPTLLVGDYLFVSKFSYGYSRFSFPMGIIPFSGRVLGDV
PKRGDVVVFKEPNDTSVDFIKRVVGLPGDRIQVIDGILNVNGEPVRRERTEDFVQREAGGSVLRLTQYQETLPNGVVHPI
LEIHGDTYFLDNTREFRVPEGHYFMMGDNRDSSQDSRATVGFVPAENLVGRAEFVFFSHDGSAAIWQVWKWPFAIRWDRF
FHSID
>Mature_244_residues
SRKKGGGLGETIKTVVYAFLIAIVIRTFAYEPFRIPSGSMIPTLLVGDYLFVSKFSYGYSRFSFPMGIIPFSGRVLGDVP
KRGDVVVFKEPNDTSVDFIKRVVGLPGDRIQVIDGILNVNGEPVRRERTEDFVQREAGGSVLRLTQYQETLPNGVVHPIL
EIHGDTYFLDNTREFRVPEGHYFMMGDNRDSSQDSRATVGFVPAENLVGRAEFVFFSHDGSAAIWQVWKWPFAIRWDRFF
HSID

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

Organism=Escherichia coli, GI1788921, Length=277, Percent_Identity=38.2671480144404, Blast_Score=148, Evalue=3e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 27768; Mature: 27637

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: PS00501 SPASE_I_1 ; PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRKKGGGLGETIKTVVYAFLIAIVIRTFAYEPFRIPSGSMIPTLLVGDYLFVSKFSYGY
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCHHHHHHHHHHHHHHHCCC
SRFSFPMGIIPFSGRVLGDVPKRGDVVVFKEPNDTSVDFIKRVVGLPGDRIQVIDGILNV
CEECCCEEEECCCCEEEECCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCEEEEHHHHCC
NGEPVRRERTEDFVQREAGGSVLRLTQYQETLPNGVVHPILEIHGDTYFLDNTREFRVPE
CCCCCHHHHHHHHHHHHCCCCEEEEEHHHHHCCCCHHHHHHEECCCEEEECCCCEEECCC
GHYFMMGDNRDSSQDSRATVGFVPAENLVGRAEFVFFSHDGSAAIWQVWKWPFAIRWDRF
CCEEEEECCCCCCCCCCCEEEEECHHHHCCCEEEEEEECCCCCHHHHHHCCCEEEEHHHH
FHSID
HHCCC
>Mature Secondary Structure 
SRKKGGGLGETIKTVVYAFLIAIVIRTFAYEPFRIPSGSMIPTLLVGDYLFVSKFSYGY
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCHHHHHHHHHHHHHHHCCC
SRFSFPMGIIPFSGRVLGDVPKRGDVVVFKEPNDTSVDFIKRVVGLPGDRIQVIDGILNV
CEECCCEEEECCCCEEEECCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCEEEEHHHHCC
NGEPVRRERTEDFVQREAGGSVLRLTQYQETLPNGVVHPILEIHGDTYFLDNTREFRVPE
CCCCCHHHHHHHHHHHHCCCCEEEEEHHHHHCCCCHHHHHHEECCCEEEECCCCEEECCC
GHYFMMGDNRDSSQDSRATVGFVPAENLVGRAEFVFFSHDGSAAIWQVWKWPFAIRWDRF
CCEEEEECCCCCCCCCCCEEEEECHHHHCCCEEEEEEECCCCCHHHHHHCCCEEEEHHHH
FHSID
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA