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The map label for this gene is hipO [H]

Identifier: 83593148

GI number: 83593148

Start: 2108933

End: 2110099

Strand: Direct

Name: hipO [H]

Synonym: Rru_A1813

Alternate gene names: 83593148

Gene position: 2108933-2110099 (Clockwise)

Preceding gene: 83593142

Following gene: 83593150

Centisome position: 48.45

GC content: 67.35

Gene sequence:

>1167_bases
ATGAGCCTTCTCGATGCCTTCAAGCCCCTGCACGCCGGGATGATCGATTGGCGCCACGACATCCACCGCCACCCCGAGCT
GGGCTATCAGGAAACCCGGACGGCGGCCAAGGTGGCGGGCCTGCTCCGCGGTTTCGGCTGTGACGCGGTGGTCGAACAGA
TCGGCGGCACCGGCGTTGTCGGCGTGCTGCGCCAGGGCGACGGGCCGATGATCGGATTGCGTGCCGATATGGACGCCTTG
CCGATTCCCGAGAGGAATGATTTCGATCACCAAAGCGTTCACCCCGGGGTCATGCACGCCTGCGGTCACGACGGTCATAC
GGCGATGCTGTTGGGCGCGGCCCGTCATCTGGCGGCGACGCGGCGTTTCCAGGGCTCGGTGGTGTTCATTTTCCAACCGG
CCGAGGAAGGTCTGGCCGGGGCGCGGGCGATGATCGAGGACGGCCTGTTCGAGCGTTGGCCGGTCGAGGCGGTCTATGGC
CTTCATAACCTGCCCGGCTTGCCGGCGGGCAGCATCTCGGTCTCCCCCGGCCCGCAACTGGCCGCCGCCGACAAGCTGGT
CATCGAGATCACCGGCCGGGGCGCCCATGCCGCCGCCCCCGAACTGGCGCGCGACCCGGTTCTGGCCGGCGCCGCCGCCG
TTCAGGCCCTGCAGCAGATCGTCTCGCGCAATGTCTCGCCGGCGGAAACGGCGGTGGTTTCCGTCACCTGCTTCAATGCC
GGGGAAACCTTTAATGTTCTGCCCGACGGCGCGACGCTGAAAGGCACCGTGCGCTACTTCTCGTCGGAAACCGGCGATTT
GGTGCGCAACCGCATCGCCCAGGTCCTCGAGGGCATCGCGCTGGCCCATGACGTATCGATCACCCTTGATCTCCAGCGCG
GCTATCCGGCCACGGTCAACAGCGCCCCCCAGGCCGATTTCGCCCGGGGCGTCGCCCGCGCCCTGCTTGGCGAGGATCTG
GCCCCGCCCCAGGAGCCGCGGATGATCGCCGAGGATTTCTCGCTGATGCTCCAGGTCAAGCCCGGCGCCTTCGGCTTTAT
CGGCAATGGCCAAAGCCCCTCGCTCCACAATCCGCGCTATGAGTTCAACGACGCCATCTTGCCCATTGGCGCCGCCTATT
TCTGCGCCCTGGCCGAAACCGCCCTGCGGCGGCCCCCTCACGGATAA

Upstream 100 bases:

>100_bases
GAAATGCGAGGATAACGAGACAGAGCGACGACGGCGCCCCAAATCAATACCACGGCCGACCAAGCCCCTTGCTTTCCTTT
TACAGAACGGACCCTTGCCC

Downstream 100 bases:

>100_bases
GGGGGCCACGGATAAGGGGGATCACCAAGGTCATCCCTGGCCCTGAAGCGCCACGACGACCAGCAGCACGGCGGCGGCGA
TCGCCGCCCAAATCAGGAAA

Product: peptidase M20D, amidohydrolase

Products: NA

Alternate protein names: Benzoylglycine amidohydrolase; Hippuricase [H]

Number of amino acids: Translated: 388; Mature: 387

Protein sequence:

>388_residues
MSLLDAFKPLHAGMIDWRHDIHRHPELGYQETRTAAKVAGLLRGFGCDAVVEQIGGTGVVGVLRQGDGPMIGLRADMDAL
PIPERNDFDHQSVHPGVMHACGHDGHTAMLLGAARHLAATRRFQGSVVFIFQPAEEGLAGARAMIEDGLFERWPVEAVYG
LHNLPGLPAGSISVSPGPQLAAADKLVIEITGRGAHAAAPELARDPVLAGAAAVQALQQIVSRNVSPAETAVVSVTCFNA
GETFNVLPDGATLKGTVRYFSSETGDLVRNRIAQVLEGIALAHDVSITLDLQRGYPATVNSAPQADFARGVARALLGEDL
APPQEPRMIAEDFSLMLQVKPGAFGFIGNGQSPSLHNPRYEFNDAILPIGAAYFCALAETALRRPPHG

Sequences:

>Translated_388_residues
MSLLDAFKPLHAGMIDWRHDIHRHPELGYQETRTAAKVAGLLRGFGCDAVVEQIGGTGVVGVLRQGDGPMIGLRADMDAL
PIPERNDFDHQSVHPGVMHACGHDGHTAMLLGAARHLAATRRFQGSVVFIFQPAEEGLAGARAMIEDGLFERWPVEAVYG
LHNLPGLPAGSISVSPGPQLAAADKLVIEITGRGAHAAAPELARDPVLAGAAAVQALQQIVSRNVSPAETAVVSVTCFNA
GETFNVLPDGATLKGTVRYFSSETGDLVRNRIAQVLEGIALAHDVSITLDLQRGYPATVNSAPQADFARGVARALLGEDL
APPQEPRMIAEDFSLMLQVKPGAFGFIGNGQSPSLHNPRYEFNDAILPIGAAYFCALAETALRRPPHG
>Mature_387_residues
SLLDAFKPLHAGMIDWRHDIHRHPELGYQETRTAAKVAGLLRGFGCDAVVEQIGGTGVVGVLRQGDGPMIGLRADMDALP
IPERNDFDHQSVHPGVMHACGHDGHTAMLLGAARHLAATRRFQGSVVFIFQPAEEGLAGARAMIEDGLFERWPVEAVYGL
HNLPGLPAGSISVSPGPQLAAADKLVIEITGRGAHAAAPELARDPVLAGAAAVQALQQIVSRNVSPAETAVVSVTCFNAG
ETFNVLPDGATLKGTVRYFSSETGDLVRNRIAQVLEGIALAHDVSITLDLQRGYPATVNSAPQADFARGVARALLGEDLA
PPQEPRMIAEDFSLMLQVKPGAFGFIGNGQSPSLHNPRYEFNDAILPIGAAYFCALAETALRRPPHG

Specific function: Required But Not Essential For Aminobenzoyl-Glutamate Utilization. May Participate In Hydrolysis Of Aminobenzoyl- Glutamate To Aminobenzoate, Either Alone Or In Combination With Abgb. [C]

COG id: COG1473

COG function: function code R; Metal-dependent amidase/aminoacylase/carboxypeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20 family [H]

Homologues:

Organism=Escherichia coli, GI87081880, Length=440, Percent_Identity=30.9090909090909, Blast_Score=121, Evalue=7e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017439
- InterPro:   IPR010168
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.32 [H]

Molecular weight: Translated: 41103; Mature: 40972

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLDAFKPLHAGMIDWRHDIHRHPELGYQETRTAAKVAGLLRGFGCDAVVEQIGGTGVV
CCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEE
GVLRQGDGPMIGLRADMDALPIPERNDFDHQSVHPGVMHACGHDGHTAMLLGAARHLAAT
EEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHH
RRFQGSVVFIFQPAEEGLAGARAMIEDGLFERWPVEAVYGLHNLPGLPAGSISVSPGPQL
HHCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCEECCCCCCC
AAADKLVIEITGRGAHAAAPELARDPVLAGAAAVQALQQIVSRNVSPAETAVVSVTCFNA
CCCCEEEEEEECCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECC
GETFNVLPDGATLKGTVRYFSSETGDLVRNRIAQVLEGIALAHDVSITLDLQRGYPATVN
CCEEEECCCCCCEEHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCC
SAPQADFARGVARALLGEDLAPPQEPRMIAEDFSLMLQVKPGAFGFIGNGQSPSLHNPRY
CCCCHHHHHHHHHHHHCCCCCCCCCCCHHHCCCEEEEEECCCCEEECCCCCCCCCCCCCC
EFNDAILPIGAAYFCALAETALRRPPHG
CCCCCCHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SLLDAFKPLHAGMIDWRHDIHRHPELGYQETRTAAKVAGLLRGFGCDAVVEQIGGTGVV
CHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEE
GVLRQGDGPMIGLRADMDALPIPERNDFDHQSVHPGVMHACGHDGHTAMLLGAARHLAAT
EEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHH
RRFQGSVVFIFQPAEEGLAGARAMIEDGLFERWPVEAVYGLHNLPGLPAGSISVSPGPQL
HHCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCEECCCCCCC
AAADKLVIEITGRGAHAAAPELARDPVLAGAAAVQALQQIVSRNVSPAETAVVSVTCFNA
CCCCEEEEEEECCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECC
GETFNVLPDGATLKGTVRYFSSETGDLVRNRIAQVLEGIALAHDVSITLDLQRGYPATVN
CCEEEECCCCCCEEHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCC
SAPQADFARGVARALLGEDLAPPQEPRMIAEDFSLMLQVKPGAFGFIGNGQSPSLHNPRY
CCCCHHHHHHHHHHHHCCCCCCCCCCCHHHCCCEEEEEECCCCEEECCCCCCCCCCCCCC
EFNDAILPIGAAYFCALAETALRRPPHG
CCCCCCHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7730270; 10688204 [H]