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The map label for this gene is frr [H]

Identifier: 83592924

GI number: 83592924

Start: 1873238

End: 1873813

Strand: Direct

Name: frr [H]

Synonym: Rru_A1589

Alternate gene names: 83592924

Gene position: 1873238-1873813 (Clockwise)

Preceding gene: 83592923

Following gene: 83592925

Centisome position: 43.03

GC content: 63.72

Gene sequence:

>576_bases
GTGTCCGATGGCGCTTCCAGTTTCGACACCTTGAAAGCCGACCTCAGGCACCGCATGGATACGGCGGTCGAAGTCTTGCG
CAAGGATTTCGCGGGGCTGCGGACCGGCCGGGCGTCGACGAGCCTGCTCGATTCCGTGATGGTCGAGGCCTATGGTCAGG
CCATGCCCTTGGCCCAGGTGGCGACGGTCAGCGTTCCCGAGCCGCGCATGATTAGCGTTCAGGTCTGGGACCGCGGAATG
GCCAAGGCCGTCGACAAGGCGATCCGCGACGCCGGCCTCGGCCTCAATCCGGCCTCCGACGGCCAGCTTATCCGCGTGCC
CATTCCGCCGCTGAACGAAGAGCGCCGCACCGAGCTGACCAAGGTCGCGGGCAAATATGCCGAGCAGACCCGTGTCGCCG
TGCGCAACGTCCGTCGCGATGGCATGGACCAGCTCAAGAAGATGGAAAAGGATAGCGCCATCAGCCAGGACGAACACAAG
AAGTTCGGCGCCGAGGTTCAGGCCTTGACCGATGAGACGATCCGTCGTCTCGACGAGGCCCTGGCCCATAAGGAACAGGA
GATCATGCAAGTCTGA

Upstream 100 bases:

>100_bases
TGGTGTTTTCCCTGCACACCCCTGGCGCTCTGGCCGATGTCCTTGATCGCCGGGGCCGTTTCACCGAGATCCTCTGCGAC
AGTCACCAGGAGTAAGAACA

Downstream 100 bases:

>100_bases
TGCAGGCCGATCCCGTGCCTTTGTTCGACGGCTCAGCCCCGTCGTCTTTCCATGTCGCCATTATCATGGATGGCAACGGG
CGCTGGGCCCATGCGCGTGG

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor [H]

Number of amino acids: Translated: 191; Mature: 190

Protein sequence:

>191_residues
MSDGASSFDTLKADLRHRMDTAVEVLRKDFAGLRTGRASTSLLDSVMVEAYGQAMPLAQVATVSVPEPRMISVQVWDRGM
AKAVDKAIRDAGLGLNPASDGQLIRVPIPPLNEERRTELTKVAGKYAEQTRVAVRNVRRDGMDQLKKMEKDSAISQDEHK
KFGAEVQALTDETIRRLDEALAHKEQEIMQV

Sequences:

>Translated_191_residues
MSDGASSFDTLKADLRHRMDTAVEVLRKDFAGLRTGRASTSLLDSVMVEAYGQAMPLAQVATVSVPEPRMISVQVWDRGM
AKAVDKAIRDAGLGLNPASDGQLIRVPIPPLNEERRTELTKVAGKYAEQTRVAVRNVRRDGMDQLKKMEKDSAISQDEHK
KFGAEVQALTDETIRRLDEALAHKEQEIMQV
>Mature_190_residues
SDGASSFDTLKADLRHRMDTAVEVLRKDFAGLRTGRASTSLLDSVMVEAYGQAMPLAQVATVSVPEPRMISVQVWDRGMA
KAVDKAIRDAGLGLNPASDGQLIRVPIPPLNEERRTELTKVAGKYAEQTRVAVRNVRRDGMDQLKKMEKDSAISQDEHKK
FGAEVQALTDETIRRLDEALAHKEQEIMQV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another [H]

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family [H]

Homologues:

Organism=Homo sapiens, GI20270317, Length=178, Percent_Identity=32.0224719101124, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI291042689, Length=157, Percent_Identity=35.031847133758, Blast_Score=85, Evalue=5e-17,
Organism=Escherichia coli, GI1786368, Length=180, Percent_Identity=50.5555555555556, Blast_Score=179, Evalue=8e-47,
Organism=Drosophila melanogaster, GI24661488, Length=186, Percent_Identity=27.9569892473118, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002661
- InterPro:   IPR015998 [H]

Pfam domain/function: PF01765 RRF [H]

EC number: NA

Molecular weight: Translated: 21158; Mature: 21027

Theoretical pI: Translated: 6.82; Mature: 6.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDGASSFDTLKADLRHRMDTAVEVLRKDFAGLRTGRASTSLLDSVMVEAYGQAMPLAQV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHH
ATVSVPEPRMISVQVWDRGMAKAVDKAIRDAGLGLNPASDGQLIRVPIPPLNEERRTELT
HCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCHHHHHHHH
KVAGKYAEQTRVAVRNVRRDGMDQLKKMEKDSAISQDEHKKFGAEVQALTDETIRRLDEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LAHKEQEIMQV
HHHHHHHHHCC
>Mature Secondary Structure 
SDGASSFDTLKADLRHRMDTAVEVLRKDFAGLRTGRASTSLLDSVMVEAYGQAMPLAQV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHH
ATVSVPEPRMISVQVWDRGMAKAVDKAIRDAGLGLNPASDGQLIRVPIPPLNEERRTELT
HCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCHHHHHHHH
KVAGKYAEQTRVAVRNVRRDGMDQLKKMEKDSAISQDEHKKFGAEVQALTDETIRRLDEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LAHKEQEIMQV
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA