Click here to switch to the map view.

The map label for this gene is uppS2 [H]

Identifier: 83592925

GI number: 83592925

Start: 1873813

End: 1874547

Strand: Direct

Name: uppS2 [H]

Synonym: Rru_A1590

Alternate gene names: 83592925

Gene position: 1873813-1874547 (Clockwise)

Preceding gene: 83592924

Following gene: 83592926

Centisome position: 43.05

GC content: 65.17

Gene sequence:

>735_bases
ATGCAGGCCGATCCCGTGCCTTTGTTCGACGGCTCAGCCCCGTCGTCTTTCCATGTCGCCATTATCATGGATGGCAACGG
GCGCTGGGCCCATGCGCGTGGCCTGCCAAGGACGGCGGGGCACAAGCGCGGGGCCGAATCCGTCCGTCGGGTGGTCGAGG
CCGCTCCCGAACTGGGCATCAGCCATCTGACGCTTTTCGGTTTCTCCTCGGAGAACTGGAAGCGGCCGGAGGGCGAGATC
AGCGACCTGATGGGGCTGCTGCGACTTTACCTGCGCAACGAGATCCGCGATCTCAAGCGCAACGGCGTGCGTCTGCGGGT
GATCGGCCGGCGGGAACGCTTCTCGCGCGATATCGTCGCCCTGATCGAGGACGGCGAGAGCGATACCCGCGACAACGATC
GCCTGCATCTGACCATCGCCCTGAATTATGGCGGGCGTCAGGAGATCGCCGACGCGGCGCGGGCCCTGGCCCGCGAGGTG
GCGGCGGGCCGCCTTGATCCCGAAGCGATCGACGAGGAGGTGCTGGGCCAGCGCCTGCTCACCGATGATCTGCCCGATCC
CGACGTTTTGGTGCGAACCAGCGGCGAACAGCGGATCAGCAATTTTCTGTTGTGGCAAATCGCCTATTCCGAACTGGTCT
TCTCCCCCGTACTCTGGCCCGAGTTCTCGCGCGATGATCTTGCCGCCGCGGTGGCCGACTTCCATCAGCGCGAACGCCGC
TTCGGCGGAGTATAA

Upstream 100 bases:

>100_bases
ACAAGAAGTTCGGCGCCGAGGTTCAGGCCTTGACCGATGAGACGATCCGTCGTCTCGACGAGGCCCTGGCCCATAAGGAA
CAGGAGATCATGCAAGTCTG

Downstream 100 bases:

>100_bases
GGAAGGGCCCGGCGGTCGAAGGTCCCCGGGATCATCAGGGAGAGGTCCTTGCTCAAGACGCGTATCCTGTCGGCCCTGGT
GCTGGCTCCGCCGGTGCTCG

Product: undecaprenyl pyrophosphate synthetase

Products: NA

Alternate protein names: UPP synthase 2; Di-trans,poly-cis-decaprenylcistransferase 2; Undecaprenyl diphosphate synthase 2; UDS 2 [H]

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
MQADPVPLFDGSAPSSFHVAIIMDGNGRWAHARGLPRTAGHKRGAESVRRVVEAAPELGISHLTLFGFSSENWKRPEGEI
SDLMGLLRLYLRNEIRDLKRNGVRLRVIGRRERFSRDIVALIEDGESDTRDNDRLHLTIALNYGGRQEIADAARALAREV
AAGRLDPEAIDEEVLGQRLLTDDLPDPDVLVRTSGEQRISNFLLWQIAYSELVFSPVLWPEFSRDDLAAAVADFHQRERR
FGGV

Sequences:

>Translated_244_residues
MQADPVPLFDGSAPSSFHVAIIMDGNGRWAHARGLPRTAGHKRGAESVRRVVEAAPELGISHLTLFGFSSENWKRPEGEI
SDLMGLLRLYLRNEIRDLKRNGVRLRVIGRRERFSRDIVALIEDGESDTRDNDRLHLTIALNYGGRQEIADAARALAREV
AAGRLDPEAIDEEVLGQRLLTDDLPDPDVLVRTSGEQRISNFLLWQIAYSELVFSPVLWPEFSRDDLAAAVADFHQRERR
FGGV
>Mature_244_residues
MQADPVPLFDGSAPSSFHVAIIMDGNGRWAHARGLPRTAGHKRGAESVRRVVEAAPELGISHLTLFGFSSENWKRPEGEI
SDLMGLLRLYLRNEIRDLKRNGVRLRVIGRRERFSRDIVALIEDGESDTRDNDRLHLTIALNYGGRQEIADAARALAREV
AAGRLDPEAIDEEVLGQRLLTDDLPDPDVLVRTSGEQRISNFLLWQIAYSELVFSPVLWPEFSRDDLAAAVADFHQRERR
FGGV

Specific function: Generates undecaprenyl pyrophosphate (UPP) from isopentenyl pyrophosphate (IPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide [H]

COG id: COG0020

COG function: function code I; Undecaprenyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPP synthase family [H]

Homologues:

Organism=Homo sapiens, GI45580742, Length=227, Percent_Identity=38.7665198237885, Blast_Score=167, Evalue=7e-42,
Organism=Homo sapiens, GI45580738, Length=227, Percent_Identity=38.7665198237885, Blast_Score=167, Evalue=1e-41,
Organism=Escherichia coli, GI1786371, Length=227, Percent_Identity=52.4229074889868, Blast_Score=231, Evalue=3e-62,
Organism=Caenorhabditis elegans, GI71993029, Length=232, Percent_Identity=32.7586206896552, Blast_Score=130, Evalue=4e-31,
Organism=Saccharomyces cerevisiae, GI6319474, Length=222, Percent_Identity=34.6846846846847, Blast_Score=117, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6323748, Length=212, Percent_Identity=29.2452830188679, Blast_Score=99, Evalue=8e-22,
Organism=Drosophila melanogaster, GI18857969, Length=225, Percent_Identity=36.8888888888889, Blast_Score=143, Evalue=9e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001441
- InterPro:   IPR018520 [H]

Pfam domain/function: PF01255 Prenyltransf [H]

EC number: =2.5.1.31 [H]

Molecular weight: Translated: 27387; Mature: 27387

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: PS01066 UPP_SYNTHETASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQADPVPLFDGSAPSSFHVAIIMDGNGRWAHARGLPRTAGHKRGAESVRRVVEAAPELGI
CCCCCCCCCCCCCCCCEEEEEEECCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCC
SHLTLFGFSSENWKRPEGEISDLMGLLRLYLRNEIRDLKRNGVRLRVIGRRERFSRDIVA
CEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHH
LIEDGESDTRDNDRLHLTIALNYGGRQEIADAARALAREVAAGRLDPEAIDEEVLGQRLL
EEECCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
TDDLPDPDVLVRTSGEQRISNFLLWQIAYSELVFSPVLWPEFSRDDLAAAVADFHQRERR
HCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
FGGV
HCCC
>Mature Secondary Structure
MQADPVPLFDGSAPSSFHVAIIMDGNGRWAHARGLPRTAGHKRGAESVRRVVEAAPELGI
CCCCCCCCCCCCCCCCEEEEEEECCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCC
SHLTLFGFSSENWKRPEGEISDLMGLLRLYLRNEIRDLKRNGVRLRVIGRRERFSRDIVA
CEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHH
LIEDGESDTRDNDRLHLTIALNYGGRQEIADAARALAREVAAGRLDPEAIDEEVLGQRLL
EEECCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
TDDLPDPDVLVRTSGEQRISNFLLWQIAYSELVFSPVLWPEFSRDDLAAAVADFHQRERR
HCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
FGGV
HCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]