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The map label for this gene is birA [H]

Identifier: 83592904

GI number: 83592904

Start: 1850561

End: 1851340

Strand: Direct

Name: birA [H]

Synonym: Rru_A1569

Alternate gene names: 83592904

Gene position: 1850561-1851340 (Clockwise)

Preceding gene: 83592903

Following gene: 83592905

Centisome position: 42.51

GC content: 68.33

Gene sequence:

>780_bases
ATGGCGCTGCCCGTCGTCGAAAGCACCAATCTTACGGCCCGCACCCTGTTTGGCGGCGCCGCGGCCAAGGATCTGGCCGC
TCTTGACCGCACCGTCGTTTGGGCGGGGGAGCAAAGCGGCGGCCGGGGGCGTCAGGCCCGAGTGTGGCATAGCCCGCCGG
GCAATCTCTATCATTCCTATCTGCTGCGCGCGCCCAAGCCGGTCGGCCAATGCGCCCAGCTGTCGTTCGTCGCGGCGGTG
GCCTTGGCCGAGGCGGTCGAGCGGCTGTGTCCGCTGGCCGATCCGCGCTGCAAATGGCCCAATGACATCGTCTGTCACGG
CGGCAAGATCTCCGGGATGCTGCTGGAACTGATCGAGGAGGGCGAGGGCGGCAATCCCTGGCTGGTGCTGGGCATCGGCG
TCAATATCATCACCGCGCCGGTGACCGGTGCGCTGTTTCCCGCCCTGGCCCTGGCCGATCTCGGCTGTGCCGTCACGGTC
GAGGACATGCTGGGCGCCATCGCCGCCCGGCTTGATCACTGGCTGGCGCGCTGGCAGGCCGAAGGCTTCGCCGGCATCCG
CGCCGCCTGGATCGCCCGGGCCTTGGGGATCGGATTCCCGATCGAGGTCCGCTTGAGCGAGGAAACGCGCCTGCCCGGGA
TCTTCCAGGGGCTGGACGCCGAGGGTCATCTTCTGCTCGAAGAGCCTTCCGGGCGGGTGCGGCGGATCTCGGCCGGTGAC
GTTTTTTTCCCCGGCCGTCACGGCGGTTCCGAGGGCTGTTCTTTGCAATCGACCGCGTAA

Upstream 100 bases:

>100_bases
GGCGCCCAGGCGGCGGCCGAGGCGCTGACCTTCGCCTCCGCCCGCTGATCGGTCCGTCTTGGATCCGTCCGCCGTATCCC
TCCCCGACGGGTGGCGCCTG

Downstream 100 bases:

>100_bases
GAGCGGTTTCGGTGAAATCGGATCGGCCAAGGCCGCTTTAAGAGATTGAGAATGAAGCAAATCGTCGTTGCGATCGCTTT
TGGATCGCTTGAGGGTTTGC

Product: biotin--acetyl-CoA-carboxylase ligase

Products: NA

Alternate protein names: Biotin--protein ligase [H]

Number of amino acids: Translated: 259; Mature: 258

Protein sequence:

>259_residues
MALPVVESTNLTARTLFGGAAAKDLAALDRTVVWAGEQSGGRGRQARVWHSPPGNLYHSYLLRAPKPVGQCAQLSFVAAV
ALAEAVERLCPLADPRCKWPNDIVCHGGKISGMLLELIEEGEGGNPWLVLGIGVNIITAPVTGALFPALALADLGCAVTV
EDMLGAIAARLDHWLARWQAEGFAGIRAAWIARALGIGFPIEVRLSEETRLPGIFQGLDAEGHLLLEEPSGRVRRISAGD
VFFPGRHGGSEGCSLQSTA

Sequences:

>Translated_259_residues
MALPVVESTNLTARTLFGGAAAKDLAALDRTVVWAGEQSGGRGRQARVWHSPPGNLYHSYLLRAPKPVGQCAQLSFVAAV
ALAEAVERLCPLADPRCKWPNDIVCHGGKISGMLLELIEEGEGGNPWLVLGIGVNIITAPVTGALFPALALADLGCAVTV
EDMLGAIAARLDHWLARWQAEGFAGIRAAWIARALGIGFPIEVRLSEETRLPGIFQGLDAEGHLLLEEPSGRVRRISAGD
VFFPGRHGGSEGCSLQSTA
>Mature_258_residues
ALPVVESTNLTARTLFGGAAAKDLAALDRTVVWAGEQSGGRGRQARVWHSPPGNLYHSYLLRAPKPVGQCAQLSFVAAVA
LAEAVERLCPLADPRCKWPNDIVCHGGKISGMLLELIEEGEGGNPWLVLGIGVNIITAPVTGALFPALALADLGCAVTVE
DMLGAIAARLDHWLARWQAEGFAGIRAAWIARALGIGFPIEVRLSEETRLPGIFQGLDAEGHLLLEEPSGRVRRISAGDV
FFPGRHGGSEGCSLQSTA

Specific function: Activates biotin to form biotinyl-5'-adenylate and transfers the biotin moiety to biotin-accepting proteins [H]

COG id: COG0340

COG function: function code H; Biotin-(acetyl-CoA carboxylase) ligase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the biotin--protein ligase family [H]

Homologues:

Organism=Escherichia coli, GI1790408, Length=230, Percent_Identity=29.5652173913043, Blast_Score=80, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004408
- InterPro:   IPR003142
- InterPro:   IPR004143 [H]

Pfam domain/function: PF02237 BPL_C; PF03099 BPL_LipA_LipB [H]

EC number: =6.3.4.15 [H]

Molecular weight: Translated: 27356; Mature: 27225

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALPVVESTNLTARTLFGGAAAKDLAALDRTVVWAGEQSGGRGRQARVWHSPPGNLYHSY
CCCCCCCCCCCCHHHHHCCHHHHHHHHHCCEEEEECCCCCCCCCEEEEEECCCCHHHHHH
LLRAPKPVGQCAQLSFVAAVALAEAVERLCPLADPRCKWPNDIVCHGGKISGMLLELIEE
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCHHHHHHHHHHC
GEGGNPWLVLGIGVNIITAPVTGALFPALALADLGCAVTVEDMLGAIAARLDHWLARWQA
CCCCCCEEEEEECCEEEECCHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHC
EGFAGIRAAWIARALGIGFPIEVRLSEETRLPGIFQGLDAEGHLLLEEPSGRVRRISAGD
CCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHCCCCCCCEEEECCCCCEEEEECCC
VFFPGRHGGSEGCSLQSTA
EECCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ALPVVESTNLTARTLFGGAAAKDLAALDRTVVWAGEQSGGRGRQARVWHSPPGNLYHSY
CCCCCCCCCCCHHHHHCCHHHHHHHHHCCEEEEECCCCCCCCCEEEEEECCCCHHHHHH
LLRAPKPVGQCAQLSFVAAVALAEAVERLCPLADPRCKWPNDIVCHGGKISGMLLELIEE
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCHHHHHHHHHHC
GEGGNPWLVLGIGVNIITAPVTGALFPALALADLGCAVTVEDMLGAIAARLDHWLARWQA
CCCCCCEEEEEECCEEEECCHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHC
EGFAGIRAAWIARALGIGFPIEVRLSEETRLPGIFQGLDAEGHLLLEEPSGRVRRISAGD
CCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHCCCCCCCEEEECCCCCEEEEECCC
VFFPGRHGGSEGCSLQSTA
EECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8422400 [H]