Click here to switch to the map view.

The map label for this gene is nuoN

Identifier: 83592903

GI number: 83592903

Start: 1849045

End: 1850508

Strand: Direct

Name: nuoN

Synonym: Rru_A1568

Alternate gene names: 83592903

Gene position: 1849045-1850508 (Clockwise)

Preceding gene: 83592902

Following gene: 83592904

Centisome position: 42.48

GC content: 63.52

Gene sequence:

>1464_bases
ATGACGTTCCAATCACTGATCCTTGGGCCCGCCCTGCCGGAAATCCTGCTGGCCGTCCTTGGTCTGGTTCTTTTGATGGT
CGGGGTGTTCCGTAAAACCGACAGCACCGGTCTGGTGGGGCTGCTGGCGGTTTACGGCCTGTTGATGGCTTTGGCCGTGG
TCGGCCTGGGGGCGGCGCCGGAAACGCCGCAACTGGCCTTTGGCGGGCTGTTCATCGATGACGGCTTCGCCCGCTATGCC
AAGGCGCTGACCCTGCTCGGCGCGGTGCTGACCCTGCTGCTGTCGATGGTGTGGCTCAAGCGCGAGAACGAGGGGCGCTT
CGAGTTCCCGATTCTGGTGCTGTTCGCCACCATCGGCATGATGATGATGATCTCGGCCAACGATCTGATCGCCCTTTACA
TGGGGTTGGAGCTTCAGTCGCTGGCGCTTTACGTGATCGCCGCCTATCAGCGCGACAATCTGAAATCCACCGAGGCCGGC
CTTAAGTATTTCGTCCTTGGCGCCCTGGCCTCGGGCCTGCTGCTCTATGGCATGTCGCTGGTTTACGGCTTCGCCGGCAC
CACCCGCTTCGACGGTCTGGCCCAGGTGGCGGCCGCCGAGGGCGGCATTTCGACCGGGTTGCTGATCGGCATCGTCTTCA
TCATCGCCGGTCTCGCCTTCAAGGTCTCGGCCGTGCCCTTCCATATGTGGGCGCCCGATGTCTATGAGGGCGCGCCGACC
CCGGTGACCGCCTTCTTCGCCGTCGCCCCCAAGATCGCCGCCCTGACCCTGTTCGCCCGGGTGATGATGGGGCCCTTCGC
CGCCTATGCCGACCAGTGGCAGCAGGTGATCATCCTGATCTCCATCCTGTCGATGCTGCTCGGCGGCTTCGCCGCCATCG
TCCAGACCAATATCAAGCGGCTGATGGCCTATAGCTCGATCGGTCACGTCGGCTATGCCCTGATCGGCATCGCCGCCGGC
ACCACCGAGGGCGTTCGCGGCGTTCTGGTCTATCTGGCGATCTATCTGTTCATGAACGTCGGCACCTTCACCGTCATCCT
GGCGATGCGCCAGAAGGGGCGGGCGGTCGAAGGCATCAACGATCTGGCCGGTCTGTCCAAGCAGCATCCGATGATGGCCG
CCGCCATGGCCGTCTTCATGTTCTCGATGGCCGGCGTACCGCCTTTGGCCGGTTTCTTCGGCAAGTTCTATGTCTTCATG
GCGGCGGTGAATTCCGGCCTGTTCGCCCTGGCGGTGATCGGCGTTCTGTCGAGCGTGGTGGCCGCCTTCTACTATCTGCG
CATCATCAAGCTGATGTATTTCGATGAGGCGACCGAACCGCTGGATGCGCTTTCGGGCACGACGATGAAGGTGATCTTGA
TCGGCACCGCCGCCGTGGTCGCCTTGTTCTTCCTGGCGCCGTCCGTGGTGGTCGATGGCGCCCAGGCGGCGGCCGAGGCG
CTGACCTTCGCCTCCGCCCGCTGA

Upstream 100 bases:

>100_bases
TCGTTTCCACCTACGAGACAGCGCTCACCGCCGCCGGGACCCCCGGTCCCGACGCGGCGGCGTCGCTGGCCCAGCGCTAA
AGGCCAAAGGGGTAGTCGCA

Downstream 100 bases:

>100_bases
TCGGTCCGTCTTGGATCCGTCCGCCGTATCCCTCCCCGACGGGTGGCGCCTGATGGCGCTGCCCGTCGTCGAAAGCACCA
ATCTTACGGCCCGCACCCTG

Product: NADH dehydrogenase subunit N

Products: NA

Alternate protein names: NADH dehydrogenase I subunit N; NDH-1 subunit N

Number of amino acids: Translated: 487; Mature: 486

Protein sequence:

>487_residues
MTFQSLILGPALPEILLAVLGLVLLMVGVFRKTDSTGLVGLLAVYGLLMALAVVGLGAAPETPQLAFGGLFIDDGFARYA
KALTLLGAVLTLLLSMVWLKRENEGRFEFPILVLFATIGMMMMISANDLIALYMGLELQSLALYVIAAYQRDNLKSTEAG
LKYFVLGALASGLLLYGMSLVYGFAGTTRFDGLAQVAAAEGGISTGLLIGIVFIIAGLAFKVSAVPFHMWAPDVYEGAPT
PVTAFFAVAPKIAALTLFARVMMGPFAAYADQWQQVIILISILSMLLGGFAAIVQTNIKRLMAYSSIGHVGYALIGIAAG
TTEGVRGVLVYLAIYLFMNVGTFTVILAMRQKGRAVEGINDLAGLSKQHPMMAAAMAVFMFSMAGVPPLAGFFGKFYVFM
AAVNSGLFALAVIGVLSSVVAAFYYLRIIKLMYFDEATEPLDALSGTTMKVILIGTAAVVALFFLAPSVVVDGAQAAAEA
LTFASAR

Sequences:

>Translated_487_residues
MTFQSLILGPALPEILLAVLGLVLLMVGVFRKTDSTGLVGLLAVYGLLMALAVVGLGAAPETPQLAFGGLFIDDGFARYA
KALTLLGAVLTLLLSMVWLKRENEGRFEFPILVLFATIGMMMMISANDLIALYMGLELQSLALYVIAAYQRDNLKSTEAG
LKYFVLGALASGLLLYGMSLVYGFAGTTRFDGLAQVAAAEGGISTGLLIGIVFIIAGLAFKVSAVPFHMWAPDVYEGAPT
PVTAFFAVAPKIAALTLFARVMMGPFAAYADQWQQVIILISILSMLLGGFAAIVQTNIKRLMAYSSIGHVGYALIGIAAG
TTEGVRGVLVYLAIYLFMNVGTFTVILAMRQKGRAVEGINDLAGLSKQHPMMAAAMAVFMFSMAGVPPLAGFFGKFYVFM
AAVNSGLFALAVIGVLSSVVAAFYYLRIIKLMYFDEATEPLDALSGTTMKVILIGTAAVVALFFLAPSVVVDGAQAAAEA
LTFASAR
>Mature_486_residues
TFQSLILGPALPEILLAVLGLVLLMVGVFRKTDSTGLVGLLAVYGLLMALAVVGLGAAPETPQLAFGGLFIDDGFARYAK
ALTLLGAVLTLLLSMVWLKRENEGRFEFPILVLFATIGMMMMISANDLIALYMGLELQSLALYVIAAYQRDNLKSTEAGL
KYFVLGALASGLLLYGMSLVYGFAGTTRFDGLAQVAAAEGGISTGLLIGIVFIIAGLAFKVSAVPFHMWAPDVYEGAPTP
VTAFFAVAPKIAALTLFARVMMGPFAAYADQWQQVIILISILSMLLGGFAAIVQTNIKRLMAYSSIGHVGYALIGIAAGT
TEGVRGVLVYLAIYLFMNVGTFTVILAMRQKGRAVEGINDLAGLSKQHPMMAAAMAVFMFSMAGVPPLAGFFGKFYVFMA
AVNSGLFALAVIGVLSSVVAAFYYLRIIKLMYFDEATEPLDALSGTTMKVILIGTAAVVALFFLAPSVVVDGAQAAAEAL
TFASAR

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1007

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 2 (chain N)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 2 family

Homologues:

Organism=Homo sapiens, GI251831108, Length=314, Percent_Identity=20.0636942675159, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI145693160, Length=449, Percent_Identity=37.8619153674833, Blast_Score=234, Evalue=7e-63,
Organism=Escherichia coli, GI1788614, Length=370, Percent_Identity=27.027027027027, Blast_Score=105, Evalue=7e-24,
Organism=Escherichia coli, GI1788831, Length=297, Percent_Identity=25.9259259259259, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1788613, Length=410, Percent_Identity=24.8780487804878, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788827, Length=328, Percent_Identity=24.390243902439, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI2367154, Length=283, Percent_Identity=27.9151943462898, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1788829, Length=277, Percent_Identity=27.0758122743682, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUON_RHORT (Q2RU27)

Other databases:

- EMBL:   CP000230
- RefSeq:   YP_426655.1
- STRING:   Q2RU27
- GeneID:   3834985
- GenomeReviews:   CP000230_GR
- KEGG:   rru:Rru_A1568
- NMPDR:   fig|1085.1.peg.2799
- HOGENOM:   HBG747830
- OMA:   MDMNTLL
- PhylomeDB:   Q2RU27
- ProtClustDB:   PRK05777
- BioCyc:   RRUB269796:RRU_A1568-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_00445
- InterPro:   IPR010096
- InterPro:   IPR001750
- TIGRFAMs:   TIGR01770

Pfam domain/function: PF00361 Oxidored_q1

EC number: =1.6.99.5

Molecular weight: Translated: 51423; Mature: 51292

Theoretical pI: Translated: 7.69; Mature: 7.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xf77963c)-; HASH(0xf43d0b4)-; HASH(0xf4e18d4)-; HASH(0xef671a0)-; HASH(0xf6c5684)-; HASH(0xe9541cc)-; HASH(0xf6c56fc)-; HASH(0xf37ca44)-; HASH(0xef87d08)-; HASH(0xf4e69b8)-; HASH(0xeaa1aa4)-; HASH(0xde80408)-; HASH(0xf2e143c)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFQSLILGPALPEILLAVLGLVLLMVGVFRKTDSTGLVGLLAVYGLLMALAVVGLGAAP
CCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
ETPQLAFGGLFIDDGFARYAKALTLLGAVLTLLLSMVWLKRENEGRFEFPILVLFATIGM
CCCCEEECCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
MMMISANDLIALYMGLELQSLALYVIAAYQRDNLKSTEAGLKYFVLGALASGLLLYGMSL
HHHHCCCCHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VYGFAGTTRFDGLAQVAAAEGGISTGLLIGIVFIIAGLAFKVSAVPFHMWAPDVYEGAPT
HHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEECCCCHHCCCCCC
PVTAFFAVAPKIAALTLFARVMMGPFAAYADQWQQVIILISILSMLLGGFAAIVQTNIKR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LMAYSSIGHVGYALIGIAAGTTEGVRGVLVYLAIYLFMNVGTFTVILAMRQKGRAVEGIN
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCH
DLAGLSKQHPMMAAAMAVFMFSMAGVPPLAGFFGKFYVFMAAVNSGLFALAVIGVLSSVV
HHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
AAFYYLRIIKLMYFDEATEPLDALSGTTMKVILIGTAAVVALFFLAPSVVVDGAQAAAEA
HHHHHHHHHHHHHHHCCCCHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHCCHHHHHHH
LTFASAR
HHHHCCH
>Mature Secondary Structure 
TFQSLILGPALPEILLAVLGLVLLMVGVFRKTDSTGLVGLLAVYGLLMALAVVGLGAAP
CHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
ETPQLAFGGLFIDDGFARYAKALTLLGAVLTLLLSMVWLKRENEGRFEFPILVLFATIGM
CCCCEEECCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
MMMISANDLIALYMGLELQSLALYVIAAYQRDNLKSTEAGLKYFVLGALASGLLLYGMSL
HHHHCCCCHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VYGFAGTTRFDGLAQVAAAEGGISTGLLIGIVFIIAGLAFKVSAVPFHMWAPDVYEGAPT
HHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEECCCCHHCCCCCC
PVTAFFAVAPKIAALTLFARVMMGPFAAYADQWQQVIILISILSMLLGGFAAIVQTNIKR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LMAYSSIGHVGYALIGIAAGTTEGVRGVLVYLAIYLFMNVGTFTVILAMRQKGRAVEGIN
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCH
DLAGLSKQHPMMAAAMAVFMFSMAGVPPLAGFFGKFYVFMAAVNSGLFALAVIGVLSSVV
HHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
AAFYYLRIIKLMYFDEATEPLDALSGTTMKVILIGTAAVVALFFLAPSVVVDGAQAAAEA
HHHHHHHHHHHHHHHCCCCHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHCCHHHHHHH
LTFASAR
HHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA