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The map label for this gene is coaX

Identifier: 83592905

GI number: 83592905

Start: 1851460

End: 1852233

Strand: Direct

Name: coaX

Synonym: Rru_A1570

Alternate gene names: 83592905

Gene position: 1851460-1852233 (Clockwise)

Preceding gene: 83592904

Following gene: 83592906

Centisome position: 42.53

GC content: 62.79

Gene sequence:

>774_bases
ATGCTTCTGGCGATTGATTCGGGCAACACCAATACGGTTTTCGCCGTCTATGACGGCGATGCCAAGCGCGGCGAATGGCG
GGCGGCGACCAACGCCAATCGCACCGCCGACGAGATGGGCGTATGGCTGTTGCAGTTGATGACGCTTGAGGGGCTTTCCC
AGGGCGATATCGATGCCACCATCATCGCCTCGGTCGTCCCCGCCACCGTGTTCAATCTGCGCATGCTCTGTCACCGCTAT
TTCCATAGCCCGCCGATGGTGGTGGGCGAGCCCGACGTCGATCTCGGCATCGGAATCCTGCTCGAACGCCCCGACGAGGT
CGGCGCCGACCGGCTGGTCAACGCCGTTGCCGCCCATGAAACCTATCGCGGACCGTTGATCGTCATCGATTTTGGCACGG
CGACGACCTTCGATGTGGTAGATGAAGAGGGCAATTATTGTGGTGGGGCCATCGCCCCGGGTGTGAATCTGTCGCTGGAG
GCCCTGCATATGGCCTCGGCACAGCTTCCCCGCGTGGCGATCGGCCGTCCGCGCACGGTCATCGGCAAGGCCACGATCCC
GGCGATGAAGTCGGGGATCTATCTGGGCTACGTCGGCTTGATCGAGGGACTGGTCAAACGTATATCGGAGGAGTTCGGCG
CGCCGATGCGGGTCATCGCCACCGGGGGGCTGGCGCCGCTATTCGCCGAAGCCACCGACGCCATCCAGACCATCGATGAC
GATTTGACCCTGCGCGGCCTACTCATCATTCACCGGCGTAACCAGCCGGACTGA

Upstream 100 bases:

>100_bases
GGATCGGCCAAGGCCGCTTTAAGAGATTGAGAATGAAGCAAATCGTCGTTGCGATCGCTTTTGGATCGCTTGAGGGTTTG
CTCTGGAACAAAGGACAATC

Downstream 100 bases:

>100_bases
CTTTCACTGGCCGCATCCGGCCCCTTTTCTCTCAGTAGACCGATCGGACCTTCCCCACCTATGGCTGACAATTCCCCGCC
CGTGCCGCCCCGTTTCGAAA

Product: pantothenate kinase

Products: NA

Alternate protein names: PanK-III; Pantothenic acid kinase

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MLLAIDSGNTNTVFAVYDGDAKRGEWRAATNANRTADEMGVWLLQLMTLEGLSQGDIDATIIASVVPATVFNLRMLCHRY
FHSPPMVVGEPDVDLGIGILLERPDEVGADRLVNAVAAHETYRGPLIVIDFGTATTFDVVDEEGNYCGGAIAPGVNLSLE
ALHMASAQLPRVAIGRPRTVIGKATIPAMKSGIYLGYVGLIEGLVKRISEEFGAPMRVIATGGLAPLFAEATDAIQTIDD
DLTLRGLLIIHRRNQPD

Sequences:

>Translated_257_residues
MLLAIDSGNTNTVFAVYDGDAKRGEWRAATNANRTADEMGVWLLQLMTLEGLSQGDIDATIIASVVPATVFNLRMLCHRY
FHSPPMVVGEPDVDLGIGILLERPDEVGADRLVNAVAAHETYRGPLIVIDFGTATTFDVVDEEGNYCGGAIAPGVNLSLE
ALHMASAQLPRVAIGRPRTVIGKATIPAMKSGIYLGYVGLIEGLVKRISEEFGAPMRVIATGGLAPLFAEATDAIQTIDD
DLTLRGLLIIHRRNQPD
>Mature_257_residues
MLLAIDSGNTNTVFAVYDGDAKRGEWRAATNANRTADEMGVWLLQLMTLEGLSQGDIDATIIASVVPATVFNLRMLCHRY
FHSPPMVVGEPDVDLGIGILLERPDEVGADRLVNAVAAHETYRGPLIVIDFGTATTFDVVDEEGNYCGGAIAPGVNLSLE
ALHMASAQLPRVAIGRPRTVIGKATIPAMKSGIYLGYVGLIEGLVKRISEEFGAPMRVIATGGLAPLFAEATDAIQTIDD
DLTLRGLLIIHRRNQPD

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAX_RHORT (Q2RU25)

Other databases:

- EMBL:   CP000230
- RefSeq:   YP_426657.1
- ProteinModelPortal:   Q2RU25
- SMR:   Q2RU25
- STRING:   Q2RU25
- GeneID:   3834987
- GenomeReviews:   CP000230_GR
- KEGG:   rru:Rru_A1570
- NMPDR:   fig|1085.1.peg.2797
- eggNOG:   COG1521
- HOGENOM:   HBG634537
- OMA:   PAIVVDF
- ProtClustDB:   PRK13318
- BioCyc:   RRUB269796:RRU_A1570-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01274
- InterPro:   IPR004619
- TIGRFAMs:   TIGR00671

Pfam domain/function: PF03309 Bvg_acc_factor

EC number: =2.7.1.33

Molecular weight: Translated: 27523; Mature: 27523

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: NA

Important sites: ACT_SITE 110-110 BINDING 133-133 BINDING 185-185

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLAIDSGNTNTVFAVYDGDAKRGEWRAATNANRTADEMGVWLLQLMTLEGLSQGDIDAT
CEEEEECCCCEEEEEEECCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHH
IIASVVPATVFNLRMLCHRYFHSPPMVVGEPDVDLGIGILLERPDEVGADRLVNAVAAHE
HHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCEEEEEECCCCCCHHHHHHHHHHHH
TYRGPLIVIDFGTATTFDVVDEEGNYCGGAIAPGVNLSLEALHMASAQLPRVAIGRPRTV
CCCCCEEEEECCCCCEEEEEECCCCCCCCEECCCCCCCHHHHHHHHHCCCEEECCCCCEE
IGKATIPAMKSGIYLGYVGLIEGLVKRISEEFGAPMRVIATGGLAPLFAEATDAIQTIDD
EECCCCHHHHCCEEEEHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHCC
DLTLRGLLIIHRRNQPD
CCEEEEEEEEEECCCCC
>Mature Secondary Structure
MLLAIDSGNTNTVFAVYDGDAKRGEWRAATNANRTADEMGVWLLQLMTLEGLSQGDIDAT
CEEEEECCCCEEEEEEECCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHH
IIASVVPATVFNLRMLCHRYFHSPPMVVGEPDVDLGIGILLERPDEVGADRLVNAVAAHE
HHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCEEEEEECCCCCCHHHHHHHHHHHH
TYRGPLIVIDFGTATTFDVVDEEGNYCGGAIAPGVNLSLEALHMASAQLPRVAIGRPRTV
CCCCCEEEEECCCCCEEEEEECCCCCCCCEECCCCCCCHHHHHHHHHCCCEEECCCCCEE
IGKATIPAMKSGIYLGYVGLIEGLVKRISEEFGAPMRVIATGGLAPLFAEATDAIQTIDD
EECCCCHHHHCCEEEEHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHCC
DLTLRGLLIIHRRNQPD
CCEEEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA