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The map label for this gene is ruvA

Identifier: 83592424

GI number: 83592424

Start: 1277967

End: 1278605

Strand: Direct

Name: ruvA

Synonym: Rru_A1088

Alternate gene names: 83592424

Gene position: 1277967-1278605 (Clockwise)

Preceding gene: 83592423

Following gene: 83592425

Centisome position: 29.36

GC content: 71.67

Gene sequence:

>639_bases
ATGATCGCCAAGCTCAAGGGACTGGTCGATTCGGTGGCCGAGGATCACGCGGTGATCGATGTCGGCGGCGTCGGCTATCT
GGTGTTCTGTCCGGCGCGGGTGCTAACCCGCCTGCCGTCACCCGGCCAAGCGGTGGCCCTGGTCGTTGAAACCCAGGTGC
GCGAGGATCACATCTCGCTTTTCGGCTTCCTGGAAACCGCCGAGCGCGACTGGTTCCGTTTGCTCTCGACCGTGCAGGGG
GTGGGATCGAAGGTGGCGTTGTCGGTGCTCTCGGTGCTCTCGGCCGGGCAGATTTCCCAGGCGATCGCCGCCGGCGACAA
GGCTGCCCTCGGCCGGGCGCCCGGGGTCGGCCCCAAGCTGGCGGCGCGCATCGCCAGCGAGTTGAAGGACAAGGCCGTCG
CCCTGGGCGGAATGCCGGCCCCGCCGCCGCGCGGCGCCGGCACCGATGCCGCCGGCGAGGGGCCGCCGGGCGGGCCGACG
GGGGATGTCCTTGGCGACGCGGTCTCGGCCCTGGTCAATCTTGGCTATGGGCGGAGCGAGGCGGTGGGGGCGGCCAGCCG
GGCCGCCGGCTTGGGGGCGACCACCGTGCAAGGGGTGATCGGTCTGGCCCTGCGCGATCTCGGCCGGGGAGGGGCATAA

Upstream 100 bases:

>100_bases
AAACCGCTGATGCCGCCGATGCCTTGGCCATCGCCATCTGTCATGCCCATTACCGGGCGGGGGCGCTGTCCCTGGCCCTG
GCCCGCGCCGGAGGGGGGCG

Downstream 100 bases:

>100_bases
TCCATGGCCGGGCACGAGGAGGAAGATGAGCGCCTGATCTCGGGGCGCCGCCGCGAGGGCGAGGTCGATGCGGCCCTGCG
CCCGCAGTCGCTGGCCGATT

Product: DNA recombination protein RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MIAKLKGLVDSVAEDHAVIDVGGVGYLVFCPARVLTRLPSPGQAVALVVETQVREDHISLFGFLETAERDWFRLLSTVQG
VGSKVALSVLSVLSAGQISQAIAAGDKAALGRAPGVGPKLAARIASELKDKAVALGGMPAPPPRGAGTDAAGEGPPGGPT
GDVLGDAVSALVNLGYGRSEAVGAASRAAGLGATTVQGVIGLALRDLGRGGA

Sequences:

>Translated_212_residues
MIAKLKGLVDSVAEDHAVIDVGGVGYLVFCPARVLTRLPSPGQAVALVVETQVREDHISLFGFLETAERDWFRLLSTVQG
VGSKVALSVLSVLSAGQISQAIAAGDKAALGRAPGVGPKLAARIASELKDKAVALGGMPAPPPRGAGTDAAGEGPPGGPT
GDVLGDAVSALVNLGYGRSEAVGAASRAAGLGATTVQGVIGLALRDLGRGGA
>Mature_212_residues
MIAKLKGLVDSVAEDHAVIDVGGVGYLVFCPARVLTRLPSPGQAVALVVETQVREDHISLFGFLETAERDWFRLLSTVQG
VGSKVALSVLSVLSAGQISQAIAAGDKAALGRAPGVGPKLAARIASELKDKAVALGGMPAPPPRGAGTDAAGEGPPGGPT
GDVLGDAVSALVNLGYGRSEAVGAASRAAGLGATTVQGVIGLALRDLGRGGA

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family

Homologues:

Organism=Escherichia coli, GI1788168, Length=205, Percent_Identity=36.5853658536585, Blast_Score=107, Evalue=5e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVA_RHORT (Q2RVF6)

Other databases:

- EMBL:   CP000230
- RefSeq:   YP_426176.1
- HSSP:   P40832
- ProteinModelPortal:   Q2RVF6
- SMR:   Q2RVF6
- STRING:   Q2RVF6
- GeneID:   3833395
- GenomeReviews:   CP000230_GR
- KEGG:   rru:Rru_A1088
- NMPDR:   fig|1085.1.peg.3283
- eggNOG:   COG0632
- HOGENOM:   HBG635309
- OMA:   AQRIVLD
- PhylomeDB:   Q2RVF6
- BioCyc:   RRUB269796:RRU_A1088-MONOMER
- HAMAP:   MF_00031
- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00278
- TIGRFAMs:   TIGR00084

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N; SSF50249 Nucleic_acid_OB; SSF47781 RuvA_2_like; SSF46929 RuvA_C-like

EC number: =3.6.4.12

Molecular weight: Translated: 21005; Mature: 21005

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAKLKGLVDSVAEDHAVIDVGGVGYLVFCPARVLTRLPSPGQAVALVVETQVREDHISL
CCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHH
FGFLETAERDWFRLLSTVQGVGSKVALSVLSVLSAGQISQAIAAGDKAALGRAPGVGPKL
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCHHH
AARIASELKDKAVALGGMPAPPPRGAGTDAAGEGPPGGPTGDVLGDAVSALVNLGYGRSE
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCH
AVGAASRAAGLGATTVQGVIGLALRDLGRGGA
HHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MIAKLKGLVDSVAEDHAVIDVGGVGYLVFCPARVLTRLPSPGQAVALVVETQVREDHISL
CCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHH
FGFLETAERDWFRLLSTVQGVGSKVALSVLSVLSAGQISQAIAAGDKAALGRAPGVGPKL
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCHHH
AARIASELKDKAVALGGMPAPPPRGAGTDAAGEGPPGGPTGDVLGDAVSALVNLGYGRSE
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCH
AVGAASRAAGLGATTVQGVIGLALRDLGRGGA
HHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA