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The map label for this gene is ruvC

Identifier: 83592423

GI number: 83592423

Start: 1277461

End: 1277970

Strand: Direct

Name: ruvC

Synonym: Rru_A1087

Alternate gene names: 83592423

Gene position: 1277461-1277970 (Clockwise)

Preceding gene: 161777627

Following gene: 83592424

Centisome position: 29.35

GC content: 69.22

Gene sequence:

>510_bases
ATGAGACTCCTGGGGCTGGATCCCGGTCTGCGGATTACCGGCTGGGGGGTGATCGAGGTGACGGGCAACCGCATCGGCCA
TGTGGCCGATGGGGTGGTGCGGTCCGACGATCGCCTGTCCCTGGCCGCCCGGCTGGCCCAGCTCCATGGCGGGATCGTCG
CCGTGCTCAAAGCCTATGAGCCGGTGGAGGCCGCCGTCGAGGAAACCTTCGTCAACCGCAATCCGGCCTCGACCCTCAAG
CTTGGTCAGGCGCGCGGCGCGGTGATGCTGGCGCCGGCCCTGGCCGGCCTCGTCGTGGCCGAATACCAGCCAAGTGTCGT
CAAGAAGGCGGTGGTCGGTACCGGCGGAGCGGCCAAGGATCAGGTGGGGATGATGATCCGCACCCTGTTGCCCGGCGCCA
CCTTGGAAACCGCTGATGCCGCCGATGCCTTGGCCATCGCCATCTGTCATGCCCATTACCGGGCGGGGGCGCTGTCCCTG
GCCCTGGCCCGCGCCGGAGGGGGGCGATGA

Upstream 100 bases:

>100_bases
CGCTGATGAAATTCCTCGACATCCTCGATGACTGCGACGATGTGCAAAGGGTCGCGGCCAATTACGAGATCGACGACGCG
ATCATGGAGAAACTGGGGGC

Downstream 100 bases:

>100_bases
TCGCCAAGCTCAAGGGACTGGTCGATTCGGTGGCCGAGGATCACGCGGTGATCGATGTCGGCGGCGTCGGCTATCTGGTG
TTCTGTCCGGCGCGGGTGCT

Product: Holliday junction resolvase

Products: NA

Alternate protein names: Holliday junction nuclease ruvC; Holliday junction resolvase ruvC

Number of amino acids: Translated: 169; Mature: 169

Protein sequence:

>169_residues
MRLLGLDPGLRITGWGVIEVTGNRIGHVADGVVRSDDRLSLAARLAQLHGGIVAVLKAYEPVEAAVEETFVNRNPASTLK
LGQARGAVMLAPALAGLVVAEYQPSVVKKAVVGTGGAAKDQVGMMIRTLLPGATLETADAADALAIAICHAHYRAGALSL
ALARAGGGR

Sequences:

>Translated_169_residues
MRLLGLDPGLRITGWGVIEVTGNRIGHVADGVVRSDDRLSLAARLAQLHGGIVAVLKAYEPVEAAVEETFVNRNPASTLK
LGQARGAVMLAPALAGLVVAEYQPSVVKKAVVGTGGAAKDQVGMMIRTLLPGATLETADAADALAIAICHAHYRAGALSL
ALARAGGGR
>Mature_169_residues
MRLLGLDPGLRITGWGVIEVTGNRIGHVADGVVRSDDRLSLAARLAQLHGGIVAVLKAYEPVEAAVEETFVNRNPASTLK
LGQARGAVMLAPALAGLVVAEYQPSVVKKAVVGTGGAAKDQVGMMIRTLLPGATLETADAADALAIAICHAHYRAGALSL
ALARAGGGR

Specific function: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leav

COG id: COG0817

COG function: function code L; Holliday junction resolvasome, endonuclease subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvC family

Homologues:

Organism=Escherichia coli, GI1788170, Length=169, Percent_Identity=41.4201183431953, Blast_Score=105, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVC_RHORT (Q2RVF7)

Other databases:

- EMBL:   CP000230
- RefSeq:   YP_426175.1
- ProteinModelPortal:   Q2RVF7
- SMR:   Q2RVF7
- STRING:   Q2RVF7
- GeneID:   3833394
- GenomeReviews:   CP000230_GR
- KEGG:   rru:Rru_A1087
- NMPDR:   fig|1085.1.peg.3284
- eggNOG:   COG0817
- HOGENOM:   HBG437552
- OMA:   RTGWGVI
- PhylomeDB:   Q2RVF7
- ProtClustDB:   PRK00039
- BioCyc:   RRUB269796:RRU_A1087-MONOMER
- HAMAP:   MF_00034
- InterPro:   IPR012337
- InterPro:   IPR020563
- InterPro:   IPR002176
- PRINTS:   PR00696
- TIGRFAMs:   TIGR00228

Pfam domain/function: PF02075 RuvC; SSF53098 RNaseH_fold

EC number: =3.1.22.4

Molecular weight: Translated: 17278; Mature: 17278

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: PS01321 RUVC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLLGLDPGLRITGWGVIEVTGNRIGHVADGVVRSDDRLSLAARLAQLHGGIVAVLKAYE
CEEECCCCCCEEECCEEEEECCCCCCHHHCCEECCCCHHHHHHHHHHHCCCHHEEHHHCC
PVEAAVEETFVNRNPASTLKLGQARGAVMLAPALAGLVVAEYQPSVVKKAVVGTGGAAKD
HHHHHHHHHHCCCCCCHHHEECCCCCEEEEHHHHHHHHHHCCCHHHHHHHHHCCCCCCHH
QVGMMIRTLLPGATLETADAADALAIAICHAHYRAGALSLALARAGGGR
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCC
>Mature Secondary Structure
MRLLGLDPGLRITGWGVIEVTGNRIGHVADGVVRSDDRLSLAARLAQLHGGIVAVLKAYE
CEEECCCCCCEEECCEEEEECCCCCCHHHCCEECCCCHHHHHHHHHHHCCCHHEEHHHCC
PVEAAVEETFVNRNPASTLKLGQARGAVMLAPALAGLVVAEYQPSVVKKAVVGTGGAAKD
HHHHHHHHHHCCCCCCHHHEECCCCCEEEEHHHHHHHHHHCCCHHHHHHHHHCCCCCCHH
QVGMMIRTLLPGATLETADAADALAIAICHAHYRAGALSLALARAGGGR
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA