Click here to switch to the map view.

The map label for this gene is pdhS [H]

Identifier: 83591667

GI number: 83591667

Start: 398582

End: 400444

Strand: Direct

Name: pdhS [H]

Synonym: Rru_A0327

Alternate gene names: 83591667

Gene position: 398582-400444 (Clockwise)

Preceding gene: 83591666

Following gene: 83591668

Centisome position: 9.16

GC content: 66.88

Gene sequence:

>1863_bases
ATGATGATGGTGGGTGCAGGCTCGTTCCAAACACCAGGCGGGGTGCCGCCCTTACCCCCGCCGCCCCGCGAAGGAGCGAC
GGGGCGGTCGTTATCGGCCAAAGCCAGGGCCCCCACCGTCTTGGGCCTGCTGGCCGCCGTCGTCCTTGTCATGCTCACTC
TGGGGCTAGGGGCCAATCTGGTTTTCCTTTATCGCGACGGCGTGGAGCGCGGCGAGGCCCAGGTTCTGGCGCTGCGCGAT
GGCGCGCGCGAACAGGCCGCTGCGGCGGTCTCGCGAATCGATCTTCTGCTCTCGGGCCTGACCGAGGGGTTGGCGTTGCG
TCCCGAGGTCGAGCGCTGGGGCGATGCGGGCATTCATGCCCTGCTGGTGCGCCAAAGGGCCCTGCTGCCGATGGTGCGCG
GGATCATCGTCACCAATGAGGCCGGGCGGCTGACCCATGATAGCGAGGCGGCGATTCCGGCGAATATGGACCTGTCCGAC
CGCGATTATGTGCGGGCCTTGCGGGCCGATCCGCAAAGCGGCCTTTACATCGGCGAACCGGTGCGCGGGCGCACCTCGGG
CCGGTGGTTCATCAGCATGAGCCGGCGCTTCACCGACCAGCAGGGCGCCTTCAAGGGGGTGGTTACCGCGGTGGTCGATC
CGGTGGCCCTGGGGACCGTCTTTTCGCCGTTTCTGCCCGGCGCGGGGGGAGAGTTGGAGGTGCTGCGCGACGACGGGCGG
GTGCTGCTGCATCTGCCCGATTTCGAACGCTTCATGGGGGCGGCCCGCGGGCACCAGTCCTTTTTCCGCGATGTCCTGGC
CGCGGCTCCCAGCGGATCCATCCGGGTCGCGGGCTCGACCGAAGAATCGGTCTATCGCCTGGAGGGCGGAGAGGCCGGGC
TGTTCTTCACCTGGGCGACGGTTCCGGGATCGCCGCTTCTGGTCACGGTGTCGGCCTCTTATGACGGGCTGCTGCGCTCC
TGGTGGCAGGTCCTGCCCTATCACCTGGGGGCGATCGCCTGCATCATCCTGGTTATCCTGGCCCTGGTGCTGAAGGTCCA
TCGCCAGATCCGCCATCTCAACGGCTTGATCGTCGCCCTGTCGAACCGCGAAGCCGCCCTGGTCGCCGCCCGGCGCTCAA
GCGAGGAGGCCAATCGCGCCAAAACGCTGTTCCTGGCCAATATGAGCCATGAATTGCGCACGCCGTTGAACGCCATCATC
GGCTTTTCCGACATGCTGGCGAACGGCATTCACGGCGCCTTGGCCGATCGTCAGCAAGACTATGCCCGCGATATCAATCT
GTCGGCCCTTCACCTGCTCGATCTGATCAACGACATCTTGGATGTCGCCAAGATCGAATCCGGAGGGTACCTGCTGCACG
AGCGGCCGTGCAATCTGGCCGCGATCATCCGCGCCGCCGAGCGCATGCTGGGCCCCCGCGTCCGCGAAAAAGGGCTGGTA
ATGGATACGGTCTGCGTCGATGGCGAGGCCTGGGTGATGGCCGATGAGCGGGCCATGCAGCAGGTGCTGCTCAATCTGCT
GTCCAATGCGGTCAAATTCACCCCCGAGGGCGGGCGGATCACCGTTTCCCTGGGGTTGAACGAGGGCGGCGGCATGGTTC
TGGTGGTGGGCGACACCGGTCCGGGCATTCCCGCCGAGCATCTGGCCCTGGTGCTCGAGCCTTTCTATCAGGTGGGCGAG
GTGGAAACCCGCAGCCACGAGGGAACCGGCCTGGGCCTGCCGCTGGCCAAGGCCCTGGTCGAAAAGCACGAGGGCGCGCT
GCGCCTGGACAGCCAGCCTGGACAGGGCACCCGGGTCAGCGTAACCCTGCCCGCCGCCCGCGTTCTGCCGCCGCAACGGC
CGCCGGTCGAGGCCAAACCTTGA

Upstream 100 bases:

>100_bases
ACACCTTCCCCTGCTGTGATACCGTTTCGCACAGGCGGAAAAGGGGAAGTGCTCGGCGTCGTCGGAAATCCCGCAAAGGG
GCCGACGGGAGTTGCAGAGC

Downstream 100 bases:

>100_bases
ACCGGCCCCTTCACGACCGGGCCGCCTTGGCGCTTTGAACCAGAGTGCGACGATGATTGGCTTGCTGTCGCGATCCCGGA
GCGGTGTGCGGGGAGCCGAT

Product: periplasmic sensor Signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 620; Mature: 620

Protein sequence:

>620_residues
MMMVGAGSFQTPGGVPPLPPPPREGATGRSLSAKARAPTVLGLLAAVVLVMLTLGLGANLVFLYRDGVERGEAQVLALRD
GAREQAAAAVSRIDLLLSGLTEGLALRPEVERWGDAGIHALLVRQRALLPMVRGIIVTNEAGRLTHDSEAAIPANMDLSD
RDYVRALRADPQSGLYIGEPVRGRTSGRWFISMSRRFTDQQGAFKGVVTAVVDPVALGTVFSPFLPGAGGELEVLRDDGR
VLLHLPDFERFMGAARGHQSFFRDVLAAAPSGSIRVAGSTEESVYRLEGGEAGLFFTWATVPGSPLLVTVSASYDGLLRS
WWQVLPYHLGAIACIILVILALVLKVHRQIRHLNGLIVALSNREAALVAARRSSEEANRAKTLFLANMSHELRTPLNAII
GFSDMLANGIHGALADRQQDYARDINLSALHLLDLINDILDVAKIESGGYLLHERPCNLAAIIRAAERMLGPRVREKGLV
MDTVCVDGEAWVMADERAMQQVLLNLLSNAVKFTPEGGRITVSLGLNEGGGMVLVVGDTGPGIPAEHLALVLEPFYQVGE
VETRSHEGTGLGLPLAKALVEKHEGALRLDSQPGQGTRVSVTLPAARVLPPQRPPVEAKP

Sequences:

>Translated_620_residues
MMMVGAGSFQTPGGVPPLPPPPREGATGRSLSAKARAPTVLGLLAAVVLVMLTLGLGANLVFLYRDGVERGEAQVLALRD
GAREQAAAAVSRIDLLLSGLTEGLALRPEVERWGDAGIHALLVRQRALLPMVRGIIVTNEAGRLTHDSEAAIPANMDLSD
RDYVRALRADPQSGLYIGEPVRGRTSGRWFISMSRRFTDQQGAFKGVVTAVVDPVALGTVFSPFLPGAGGELEVLRDDGR
VLLHLPDFERFMGAARGHQSFFRDVLAAAPSGSIRVAGSTEESVYRLEGGEAGLFFTWATVPGSPLLVTVSASYDGLLRS
WWQVLPYHLGAIACIILVILALVLKVHRQIRHLNGLIVALSNREAALVAARRSSEEANRAKTLFLANMSHELRTPLNAII
GFSDMLANGIHGALADRQQDYARDINLSALHLLDLINDILDVAKIESGGYLLHERPCNLAAIIRAAERMLGPRVREKGLV
MDTVCVDGEAWVMADERAMQQVLLNLLSNAVKFTPEGGRITVSLGLNEGGGMVLVVGDTGPGIPAEHLALVLEPFYQVGE
VETRSHEGTGLGLPLAKALVEKHEGALRLDSQPGQGTRVSVTLPAARVLPPQRPPVEAKP
>Mature_620_residues
MMMVGAGSFQTPGGVPPLPPPPREGATGRSLSAKARAPTVLGLLAAVVLVMLTLGLGANLVFLYRDGVERGEAQVLALRD
GAREQAAAAVSRIDLLLSGLTEGLALRPEVERWGDAGIHALLVRQRALLPMVRGIIVTNEAGRLTHDSEAAIPANMDLSD
RDYVRALRADPQSGLYIGEPVRGRTSGRWFISMSRRFTDQQGAFKGVVTAVVDPVALGTVFSPFLPGAGGELEVLRDDGR
VLLHLPDFERFMGAARGHQSFFRDVLAAAPSGSIRVAGSTEESVYRLEGGEAGLFFTWATVPGSPLLVTVSASYDGLLRS
WWQVLPYHLGAIACIILVILALVLKVHRQIRHLNGLIVALSNREAALVAARRSSEEANRAKTLFLANMSHELRTPLNAII
GFSDMLANGIHGALADRQQDYARDINLSALHLLDLINDILDVAKIESGGYLLHERPCNLAAIIRAAERMLGPRVREKGLV
MDTVCVDGEAWVMADERAMQQVLLNLLSNAVKFTPEGGRITVSLGLNEGGGMVLVVGDTGPGIPAEHLALVLEPFYQVGE
VETRSHEGTGLGLPLAKALVEKHEGALRLDSQPGQGTRVSVTLPAARVLPPQRPPVEAKP

Specific function: Functions as a polar differentiation marker. Essential protein that, by localizing in the old pole of dividing cells, controls cell division and maturation, probably through control of DivK phosphorylation status and cellular distribution, which in turn r

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm. Note=Localizes at the old pole of dividing cells. Colocalizes with divK (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=282, Percent_Identity=35.1063829787234, Blast_Score=137, Evalue=3e-33,
Organism=Escherichia coli, GI1789149, Length=233, Percent_Identity=36.0515021459227, Blast_Score=132, Evalue=1e-31,
Organism=Escherichia coli, GI48994928, Length=298, Percent_Identity=31.8791946308725, Blast_Score=130, Evalue=3e-31,
Organism=Escherichia coli, GI1788713, Length=259, Percent_Identity=34.7490347490347, Blast_Score=129, Evalue=5e-31,
Organism=Escherichia coli, GI87081816, Length=270, Percent_Identity=35.1851851851852, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1786600, Length=257, Percent_Identity=31.5175097276265, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1786912, Length=293, Percent_Identity=28.3276450511945, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI87082128, Length=260, Percent_Identity=28.4615384615385, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1788393, Length=235, Percent_Identity=25.9574468085106, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1786783, Length=236, Percent_Identity=28.3898305084746, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1790436, Length=219, Percent_Identity=26.9406392694064, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1790346, Length=234, Percent_Identity=25.2136752136752, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788549, Length=273, Percent_Identity=26.7399267399267, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI1790861, Length=190, Percent_Identity=28.9473684210526, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1787894, Length=234, Percent_Identity=28.6324786324786, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1788279, Length=207, Percent_Identity=26.5700483091787, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 66348; Mature: 66348

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMMVGAGSFQTPGGVPPLPPPPREGATGRSLSAKARAPTVLGLLAAVVLVMLTLGLGANL
CEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCE
VFLYRDGVERGEAQVLALRDGAREQAAAAVSRIDLLLSGLTEGLALRPEVERWGDAGIHA
EEEEECCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCHHH
LLVRQRALLPMVRGIIVTNEAGRLTHDSEAAIPANMDLSDRDYVRALRADPQSGLYIGEP
HHHHHHHHHHHHHCEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCEECCC
VRGRTSGRWFISMSRRFTDQQGAFKGVVTAVVDPVALGTVFSPFLPGAGGELEVLRDDGR
CCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCE
VLLHLPDFERFMGAARGHQSFFRDVLAAAPSGSIRVAGSTEESVYRLEGGEAGLFFTWAT
EEEECCCHHHHHHHHCCHHHHHHHHHHHCCCCCEEEECCCCCCEEEECCCCCEEEEEEEE
VPGSPLLVTVSASYDGLLRSWWQVLPYHLGAIACIILVILALVLKVHRQIRHLNGLIVAL
CCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
SNREAALVAARRSSEEANRAKTLFLANMSHELRTPLNAIIGFSDMLANGIHGALADRQQD
CCCCEEEEEEHHCCHHHHHHEEEEEECCCHHHHCHHHHHHCHHHHHHCCHHHHHHHHHHH
YARDINLSALHLLDLINDILDVAKIESGGYLLHERPCNLAAIIRAAERMLGPRVREKGLV
HHHCCCHHHHHHHHHHHHHHHHHEECCCCEEEECCCCCHHHHHHHHHHHHCCHHHHCCCE
MDTVCVDGEAWVMADERAMQQVLLNLLSNAVKFTPEGGRITVSLGLNEGGGMVLVVGDTG
EEEEEECCCEEEEECHHHHHHHHHHHHHHHEEECCCCCEEEEEEEECCCCCEEEEECCCC
PGIPAEHLALVLEPFYQVGEVETRSHEGTGLGLPLAKALVEKHEGALRLDSQPGQGTRVS
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEECCCCCCCCEEE
VTLPAARVLPPQRPPVEAKP
EECCHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MMMVGAGSFQTPGGVPPLPPPPREGATGRSLSAKARAPTVLGLLAAVVLVMLTLGLGANL
CEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCE
VFLYRDGVERGEAQVLALRDGAREQAAAAVSRIDLLLSGLTEGLALRPEVERWGDAGIHA
EEEEECCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCHHH
LLVRQRALLPMVRGIIVTNEAGRLTHDSEAAIPANMDLSDRDYVRALRADPQSGLYIGEP
HHHHHHHHHHHHHCEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCEECCC
VRGRTSGRWFISMSRRFTDQQGAFKGVVTAVVDPVALGTVFSPFLPGAGGELEVLRDDGR
CCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCE
VLLHLPDFERFMGAARGHQSFFRDVLAAAPSGSIRVAGSTEESVYRLEGGEAGLFFTWAT
EEEECCCHHHHHHHHCCHHHHHHHHHHHCCCCCEEEECCCCCCEEEECCCCCEEEEEEEE
VPGSPLLVTVSASYDGLLRSWWQVLPYHLGAIACIILVILALVLKVHRQIRHLNGLIVAL
CCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
SNREAALVAARRSSEEANRAKTLFLANMSHELRTPLNAIIGFSDMLANGIHGALADRQQD
CCCCEEEEEEHHCCHHHHHHEEEEEECCCHHHHCHHHHHHCHHHHHHCCHHHHHHHHHHH
YARDINLSALHLLDLINDILDVAKIESGGYLLHERPCNLAAIIRAAERMLGPRVREKGLV
HHHCCCHHHHHHHHHHHHHHHHHEECCCCEEEECCCCCHHHHHHHHHHHHCCHHHHCCCE
MDTVCVDGEAWVMADERAMQQVLLNLLSNAVKFTPEGGRITVSLGLNEGGGMVLVVGDTG
EEEEEECCCEEEEECHHHHHHHHHHHHHHHEEECCCCCEEEEEEEECCCCCEEEEECCCC
PGIPAEHLALVLEPFYQVGEVETRSHEGTGLGLPLAKALVEKHEGALRLDSQPGQGTRVS
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEECCCCCCCCEEE
VTLPAARVLPPQRPPVEAKP
EECCHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA