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The map label for this gene is qor [C]

Identifier: 83591428

GI number: 83591428

Start: 101509

End: 102531

Strand: Direct

Name: qor [C]

Synonym: Rru_A0088

Alternate gene names: 83591428

Gene position: 101509-102531 (Clockwise)

Preceding gene: 83591427

Following gene: 83591429

Centisome position: 2.33

GC content: 66.57

Gene sequence:

>1023_bases
ATGAAAGCCGTCGGTACCCACGCCCCCCTGCCCATCGATCATCCCGAGGCCCTGCTTGATCTGGAGATCGACAAGCCGGT
TCCCGGACCCCGCGACCTGCTGGTTCGCATCGAAGCCATCTCGGTCAATCCGGTCGATACCAAGACCCGCAAGACCCGCC
CGGCCAGCCCGGAGAACCCGGCGATCCTCGGCTGGGACGCCGCGGGCGTCGTGGAAGCGGTGGGCGAGTCGGTGACGCTG
TTCAAGCCGGGCGAGGCGGTCTATTACGCCGGCGATCTGACGCGGCCGGGCACCAATGCCCAATTCCATCTGGTCGACGA
GCGCCTCGCCGCCCTCAAGCCGACCAGTCTGGATTTCGCCGAGGCCGCCGCCCTGCCGCTGACGACGATCACCGCCTACG
AGATGCTGTTTGATCGCCTGGGCGTTCCCCGGTCGTCACCCGAGGCCCTGGGCGAGGTCCGTTCGATCCTGATCGTCGGC
GGGGCCGGCGGCGTTGGCTCGATCGCCATTCAGTTGGCGCGGCGGCTGACCGGGCTGACGGTGATCGCCACCGCCTCGCG
CCCGGAAACCCGCGATTGGGTGAGCGCCATGGGCGCCCACCATGTGGTCGATCATCGCGGCGATCTGGCCGAACAGATCA
ACGCCCTGGGCGTCGGCCCGGTCGGCTTCATCTTTTCGACCACCCAAACGCCCAGCCATTTCCCGGCCCTGGCCAAAATC
ATCGCCCCCCAGGGGCGGATCGGCATGATCGATGACGGCGTCGGCCTGGATTTTTCCCTGCTTAAGACCAAAAGCGCCTC
GCTGCATTGGGAATTCATGTACACCCGCTCGATGTTCCATACCGAGGACATGATCGCCCAGCACAGCTTGCTGAGCGAGG
TCGCCGGTTTGATCGACGACGGCACGCTGCGCACCACGCTGACCGCCACCGACGGGCCGATCTCGGCGGCGACGCTGAAG
GCCGCCCATGCGACCCAGGAAAGCGGCACGACCATCGGCAAGCGCGTGCTGGTCGGTTTCTAA

Upstream 100 bases:

>100_bases
CGCTCTAACCCACTGATAGTCAAGCAAATCGTCGTCGTGATCGAGAACGGATCACTCGGGATTTGCTCTAGCCCAGTCTT
GTTCTCGCGGAGCCCTATCC

Downstream 100 bases:

>100_bases
GCGCCCGGTTCCGGCGGAAAAGGCGGTCGCGGCCGCTTTTTCCGCCAAGCCGGCATCGCGGCGCCTATACTCGGCCCTCG
TTTTTCCCCCGTCGTTTTTC

Product: zinc-containing alcohol dehydrogenase superfamily protein

Products: NADP(+); Semiquinone. [C]

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MKAVGTHAPLPIDHPEALLDLEIDKPVPGPRDLLVRIEAISVNPVDTKTRKTRPASPENPAILGWDAAGVVEAVGESVTL
FKPGEAVYYAGDLTRPGTNAQFHLVDERLAALKPTSLDFAEAAALPLTTITAYEMLFDRLGVPRSSPEALGEVRSILIVG
GAGGVGSIAIQLARRLTGLTVIATASRPETRDWVSAMGAHHVVDHRGDLAEQINALGVGPVGFIFSTTQTPSHFPALAKI
IAPQGRIGMIDDGVGLDFSLLKTKSASLHWEFMYTRSMFHTEDMIAQHSLLSEVAGLIDDGTLRTTLTATDGPISAATLK
AAHATQESGTTIGKRVLVGF

Sequences:

>Translated_340_residues
MKAVGTHAPLPIDHPEALLDLEIDKPVPGPRDLLVRIEAISVNPVDTKTRKTRPASPENPAILGWDAAGVVEAVGESVTL
FKPGEAVYYAGDLTRPGTNAQFHLVDERLAALKPTSLDFAEAAALPLTTITAYEMLFDRLGVPRSSPEALGEVRSILIVG
GAGGVGSIAIQLARRLTGLTVIATASRPETRDWVSAMGAHHVVDHRGDLAEQINALGVGPVGFIFSTTQTPSHFPALAKI
IAPQGRIGMIDDGVGLDFSLLKTKSASLHWEFMYTRSMFHTEDMIAQHSLLSEVAGLIDDGTLRTTLTATDGPISAATLK
AAHATQESGTTIGKRVLVGF
>Mature_340_residues
MKAVGTHAPLPIDHPEALLDLEIDKPVPGPRDLLVRIEAISVNPVDTKTRKTRPASPENPAILGWDAAGVVEAVGESVTL
FKPGEAVYYAGDLTRPGTNAQFHLVDERLAALKPTSLDFAEAAALPLTTITAYEMLFDRLGVPRSSPEALGEVRSILIVG
GAGGVGSIAIQLARRLTGLTVIATASRPETRDWVSAMGAHHVVDHRGDLAEQINALGVGPVGFIFSTTQTPSHFPALAKI
IAPQGRIGMIDDGVGLDFSLLKTKSASLHWEFMYTRSMFHTEDMIAQHSLLSEVAGLIDDGTLRTTLTATDGPISAATLK
AAHATQESGTTIGKRVLVGF

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=195, Percent_Identity=36.9230769230769, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI13236495, Length=195, Percent_Identity=36.9230769230769, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI194239676, Length=195, Percent_Identity=36.9230769230769, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI47519420, Length=311, Percent_Identity=27.3311897106109, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI24308257, Length=200, Percent_Identity=29, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI18379349, Length=190, Percent_Identity=33.1578947368421, Blast_Score=69, Evalue=7e-12,
Organism=Escherichia coli, GI1790485, Length=203, Percent_Identity=31.0344827586207, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71987554, Length=176, Percent_Identity=34.0909090909091, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17507255, Length=243, Percent_Identity=31.6872427983539, Blast_Score=83, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR014182
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: 1.6.5.5 [C]

Molecular weight: Translated: 35999; Mature: 35999

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: PS00136 SUBTILASE_ASP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAVGTHAPLPIDHPEALLDLEIDKPVPGPRDLLVRIEAISVNPVDTKTRKTRPASPENP
CCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHEEEEEEEEEECCCCCCCCCCCCCCCCCC
AILGWDAAGVVEAVGESVTLFKPGEAVYYAGDLTRPGTNAQFHLVDERLAALKPTSLDFA
EEEECCHHHHHHHCCCEEEEECCCCEEEEECCCCCCCCCCEEEEHHHHHHHCCCCCCCHH
EAAALPLTTITAYEMLFDRLGVPRSSPEALGEVRSILIVGGAGGVGSIAIQLARRLTGLT
HHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHCEEEEEEECCCCHHHHHHHHHHHHCCEE
VIATASRPETRDWVSAMGAHHVVDHRGDLAEQINALGVGPVGFIFSTTQTPSHFPALAKI
EEEECCCCCHHHHHHHHCHHHHHHCCCCHHHHHHHCCCCCHHEEEECCCCCCHHHHHHHH
IAPQGRIGMIDDGVGLDFSLLKTKSASLHWEFMYTRSMFHTEDMIAQHSLLSEVAGLIDD
HCCCCCEEEEECCCCCCCHHEECCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCC
GTLRTTLTATDGPISAATLKAAHATQESGTTIGKRVLVGF
CCEEEEEEECCCCCCHHHHHHHHCCCCCCCHHHCEEEECC
>Mature Secondary Structure
MKAVGTHAPLPIDHPEALLDLEIDKPVPGPRDLLVRIEAISVNPVDTKTRKTRPASPENP
CCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHEEEEEEEEEECCCCCCCCCCCCCCCCCC
AILGWDAAGVVEAVGESVTLFKPGEAVYYAGDLTRPGTNAQFHLVDERLAALKPTSLDFA
EEEECCHHHHHHHCCCEEEEECCCCEEEEECCCCCCCCCCEEEEHHHHHHHCCCCCCCHH
EAAALPLTTITAYEMLFDRLGVPRSSPEALGEVRSILIVGGAGGVGSIAIQLARRLTGLT
HHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHCEEEEEEECCCCHHHHHHHHHHHHCCEE
VIATASRPETRDWVSAMGAHHVVDHRGDLAEQINALGVGPVGFIFSTTQTPSHFPALAKI
EEEECCCCCHHHHHHHHCHHHHHHCCCCHHHHHHHCCCCCHHEEEECCCCCCHHHHHHHH
IAPQGRIGMIDDGVGLDFSLLKTKSASLHWEFMYTRSMFHTEDMIAQHSLLSEVAGLIDD
HCCCCCEEEEECCCCCCCHHEECCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCC
GTLRTTLTATDGPISAATLKAAHATQESGTTIGKRVLVGF
CCEEEEEEECCCCCCHHHHHHHHCCCCCCCHHHCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 0.017 {9,10-phenanthrenequinone}} 0.0153 {2,6-dichlorophenolindophenol}} 0.013 {2,6-dichlorophenolindophenol}} 0.065 {1,4-benzoquinone}} 0.007 {NADPH}} 0.0069 {NADPH}} 0.26 {1,4-naphthoquinone}} 0.0024 {1,2-naphthoquinone}} [C]

Substrates: NADPH; Quinone [C]

Specific reaction: NADPH + Quinone = NADP(+) + Semiquinone. [C]

General reaction: Oxidation; Reduction [C]

Inhibitor: 2, 3-Dimercaptopropanol; 2, 5-Dichloro-3, 6-dihydroxy -1, 4-benzoquinone; 4-Hydroxy coumarin; 5, 5'-Dithiobis (2-nitrobenzoate); ADP; Cibacronblue3GA; Coumarin; Cu2+; Dicoumarol warfarin, coumarin; Dithiothreitol preincubation with 9, 10-phenanthrenequino

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA