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The map label for this gene is recQ [H]

Identifier: 83591429

GI number: 83591429

Start: 102652

End: 104541

Strand: Direct

Name: recQ [H]

Synonym: Rru_A0089

Alternate gene names: 83591429

Gene position: 102652-104541 (Clockwise)

Preceding gene: 83591428

Following gene: 83591430

Centisome position: 2.36

GC content: 68.62

Gene sequence:

>1890_bases
ATGGTTCCCGACGTTTCCCCTCTCCCATCCCCCGGTTCCCCCCTCCCATCCCCCGGTTCGCCCTGCGCGGACGCGGTCTC
CGCCGATCCCGCCCGCGTGTTGTTGGCTGATATCTGGGGATTCAAGGATTTCCGCCCCGGTCAGGAAGCGATCATCCGCG
CCGTGCTGGGCGGCGAGGACGTGCTGGCGGTCATGCCGACCGGGTCGGGCAAATCGCTGTGCTACCAACTGCCGGCGCTG
ATGCGCCAGGGGGTGACCCTGGTCGTCTCGCCGCTGATCGCCCTGATGCGCGATCAGGTGGCCCAGCTTGACGCCCTGGG
GGTGGCCGCCGGGGCGCTGAATTCCTCGATCGACATGGACGGCTATCGCCGCGTGATGGATGGGTTGCGCGGCGGCCGTC
TCAAGCTGCTCTACGTCGCCCCCGAACGGCTGGCCCGCCCCGATACCCTGTCCCTGCTGCGCGACAGCGGGGTGACGGCC
CTAGCCATCGACGAGGCCCATTGCGTCAGCCAATGGGGCCACGACTTCCGCCCCGACTACCTGTGTCTGGGCAAGGTGCG
CGAGGATCTGGGCGGGGTGCAGACGGTGGCCTTCACCGCCACCGCCGATGCCGCCACCCGCGATGATATCGCCGGACGGC
TGTTCCCGGCGCCGCCGCGCCTGTTCATCGGCGGCTTCGATCGCCCCAACCTGCGCCTTGCCATGCGGCCCAAGGGCGAC
ACCCGGCGGCGGATGTTCGAGTTCGTCGCCGCCCATACGGGCGAAAGCGGCGTGATCTATTGCGGCAGCCGGGCGCGCAC
CGAGGAATTGGCCGAGGGCCTGCGCGGCGCCGGCCACCGGGCCTTGCCCTATCACGCCGGCCTCGACAAGCCGGTGCGCG
ACGCCAATCAGGATGCCTTCCTGGCCGAGGACGGGCTGGTGATGGTCGCCACCGTCGCCTTTGGCATGGGCATCGACAAG
CCCGATGTCCGCTTCGTCTGCCATGCCGATATGCCGCGCTCGATCGAGGCCTATTATCAGGAGATCGGCCGCGCCGGCCG
CGATGGTCTGGCCGCCGATACCCTGACCTTCTATGGCCTGGACGATGTCCGCCTGCACCGCATGCGCATCGAGGAAAGTC
AGGCCGGCGACGAGCAAAAGCGCGTCGAGATCCAGCGGCTGAACGCCCTGCTGGCGCTGTGCGAAGCGCCGCGCTGCCGG
CGCCAGACCCTGCTCGGCTATTTCGGCGAACGCACCGAGCCGTGCGGCAATTGCGATCTATGCATCAATGGCGTGGAAAG
CTTCGACGGCACCATCGAGGCCCAGAAGGCGATGTCGGCGATGCTGCGCACCGGCCAGCGCTTCGCCACCGAGCATCTGA
TCAATATCCTGGTCGGCACCCAGACCGACGCCATCACCCAGTACGGTCACGATAAATTGCCGACCTTCGGCGTGGGCAAG
GATCACACGCGCAATGTCTGGCGCTCGATCTTCCGCCAGATCAGCGCCGGCGGCCTGATCAGCCTGGATATCGCCAATCA
TGGCCGCTGGCTGATGACCGAGGCCGGCCGCGCGGTGCTGCGCGGACAGGCGGGCGTCGCGCTGCGCTCCGATGTGCTCG
AAGCCGCCGGCCGCGGCGAGCGCAAGGACAAGGAGCGCCGGGCCAGTGCTCCGGCCGTCCAGCTCGAGGCCGACGATCGC
GCCCTGTTCGACGCCCTGCGCGCCAAGCGCCAGGAGCTGGCGCGGGCCGAAAACGTGCCGGCCTATGTGGTCTTCGCCGA
TCGCACCCTGATCGAACTGGCGACCAAACGCCCGCCCAGCCTTGACGCCATGCGCGAGATCCACGGCATCGGCCAAAGCA
AGCTCGCCCGCTACGGCGCGGCCTTCCTCGAGGTGATCACCGCCGGCTGA

Upstream 100 bases:

>100_bases
AGGCGGTCGCGGCCGCTTTTTCCGCCAAGCCGGCATCGCGGCGCCTATACTCGGCCCTCGTTTTTCCCCCGTCGTTTTTC
GCCCTTCCTGCGGACGCCTG

Downstream 100 bases:

>100_bases
GGCGCCGATTCACCGGTGCCGAGTCCCCCGGCGTTCTGAAAACCGCCGGGGTGAAAGTCAGCATGGAGGGGCGAGGACGT
TGGATGGACAACCTCCGATC

Product: ATP-dependent DNA helicase RecQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 629; Mature: 629

Protein sequence:

>629_residues
MVPDVSPLPSPGSPLPSPGSPCADAVSADPARVLLADIWGFKDFRPGQEAIIRAVLGGEDVLAVMPTGSGKSLCYQLPAL
MRQGVTLVVSPLIALMRDQVAQLDALGVAAGALNSSIDMDGYRRVMDGLRGGRLKLLYVAPERLARPDTLSLLRDSGVTA
LAIDEAHCVSQWGHDFRPDYLCLGKVREDLGGVQTVAFTATADAATRDDIAGRLFPAPPRLFIGGFDRPNLRLAMRPKGD
TRRRMFEFVAAHTGESGVIYCGSRARTEELAEGLRGAGHRALPYHAGLDKPVRDANQDAFLAEDGLVMVATVAFGMGIDK
PDVRFVCHADMPRSIEAYYQEIGRAGRDGLAADTLTFYGLDDVRLHRMRIEESQAGDEQKRVEIQRLNALLALCEAPRCR
RQTLLGYFGERTEPCGNCDLCINGVESFDGTIEAQKAMSAMLRTGQRFATEHLINILVGTQTDAITQYGHDKLPTFGVGK
DHTRNVWRSIFRQISAGGLISLDIANHGRWLMTEAGRAVLRGQAGVALRSDVLEAAGRGERKDKERRASAPAVQLEADDR
ALFDALRAKRQELARAENVPAYVVFADRTLIELATKRPPSLDAMREIHGIGQSKLARYGAAFLEVITAG

Sequences:

>Translated_629_residues
MVPDVSPLPSPGSPLPSPGSPCADAVSADPARVLLADIWGFKDFRPGQEAIIRAVLGGEDVLAVMPTGSGKSLCYQLPAL
MRQGVTLVVSPLIALMRDQVAQLDALGVAAGALNSSIDMDGYRRVMDGLRGGRLKLLYVAPERLARPDTLSLLRDSGVTA
LAIDEAHCVSQWGHDFRPDYLCLGKVREDLGGVQTVAFTATADAATRDDIAGRLFPAPPRLFIGGFDRPNLRLAMRPKGD
TRRRMFEFVAAHTGESGVIYCGSRARTEELAEGLRGAGHRALPYHAGLDKPVRDANQDAFLAEDGLVMVATVAFGMGIDK
PDVRFVCHADMPRSIEAYYQEIGRAGRDGLAADTLTFYGLDDVRLHRMRIEESQAGDEQKRVEIQRLNALLALCEAPRCR
RQTLLGYFGERTEPCGNCDLCINGVESFDGTIEAQKAMSAMLRTGQRFATEHLINILVGTQTDAITQYGHDKLPTFGVGK
DHTRNVWRSIFRQISAGGLISLDIANHGRWLMTEAGRAVLRGQAGVALRSDVLEAAGRGERKDKERRASAPAVQLEADDR
ALFDALRAKRQELARAENVPAYVVFADRTLIELATKRPPSLDAMREIHGIGQSKLARYGAAFLEVITAG
>Mature_629_residues
MVPDVSPLPSPGSPLPSPGSPCADAVSADPARVLLADIWGFKDFRPGQEAIIRAVLGGEDVLAVMPTGSGKSLCYQLPAL
MRQGVTLVVSPLIALMRDQVAQLDALGVAAGALNSSIDMDGYRRVMDGLRGGRLKLLYVAPERLARPDTLSLLRDSGVTA
LAIDEAHCVSQWGHDFRPDYLCLGKVREDLGGVQTVAFTATADAATRDDIAGRLFPAPPRLFIGGFDRPNLRLAMRPKGD
TRRRMFEFVAAHTGESGVIYCGSRARTEELAEGLRGAGHRALPYHAGLDKPVRDANQDAFLAEDGLVMVATVAFGMGIDK
PDVRFVCHADMPRSIEAYYQEIGRAGRDGLAADTLTFYGLDDVRLHRMRIEESQAGDEQKRVEIQRLNALLALCEAPRCR
RQTLLGYFGERTEPCGNCDLCINGVESFDGTIEAQKAMSAMLRTGQRFATEHLINILVGTQTDAITQYGHDKLPTFGVGK
DHTRNVWRSIFRQISAGGLISLDIANHGRWLMTEAGRAVLRGQAGVALRSDVLEAAGRGERKDKERRASAPAVQLEADDR
ALFDALRAKRQELARAENVPAYVVFADRTLIELATKRPPSLDAMREIHGIGQSKLARYGAAFLEVITAG

Specific function: Involved in the recF recombination pathway; its gene expression is under the regulation of the SOS system. It is a DNA helicase [H]

COG id: COG0514

COG function: function code L; Superfamily II DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Homo sapiens, GI4557365, Length=631, Percent_Identity=33.9144215530903, Blast_Score=319, Evalue=5e-87,
Organism=Homo sapiens, GI14591902, Length=405, Percent_Identity=39.0123456790123, Blast_Score=285, Evalue=6e-77,
Organism=Homo sapiens, GI14591904, Length=405, Percent_Identity=39.0123456790123, Blast_Score=285, Evalue=6e-77,
Organism=Homo sapiens, GI169218196, Length=536, Percent_Identity=33.955223880597, Blast_Score=275, Evalue=1e-73,
Organism=Homo sapiens, GI110735439, Length=536, Percent_Identity=33.955223880597, Blast_Score=274, Evalue=2e-73,
Organism=Homo sapiens, GI148612816, Length=420, Percent_Identity=38.5714285714286, Blast_Score=267, Evalue=2e-71,
Organism=Homo sapiens, GI51242943, Length=391, Percent_Identity=38.8746803069054, Blast_Score=253, Evalue=3e-67,
Organism=Homo sapiens, GI51242947, Length=391, Percent_Identity=38.8746803069054, Blast_Score=253, Evalue=5e-67,
Organism=Homo sapiens, GI284005309, Length=451, Percent_Identity=36.8070953436807, Blast_Score=201, Evalue=2e-51,
Organism=Homo sapiens, GI41327771, Length=400, Percent_Identity=24.25, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI188035877, Length=341, Percent_Identity=25.2199413489736, Blast_Score=77, Evalue=6e-14,
Organism=Homo sapiens, GI4758138, Length=334, Percent_Identity=25.4491017964072, Blast_Score=72, Evalue=2e-12,
Organism=Escherichia coli, GI48994977, Length=607, Percent_Identity=45.4695222405272, Blast_Score=525, Evalue=1e-150,
Organism=Escherichia coli, GI87082221, Length=352, Percent_Identity=26.1363636363636, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787016, Length=353, Percent_Identity=24.929178470255, Blast_Score=68, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25145561, Length=527, Percent_Identity=36.4326375711575, Blast_Score=299, Evalue=3e-81,
Organism=Caenorhabditis elegans, GI71987993, Length=443, Percent_Identity=38.6004514672686, Blast_Score=298, Evalue=4e-81,
Organism=Caenorhabditis elegans, GI71987997, Length=443, Percent_Identity=38.6004514672686, Blast_Score=298, Evalue=4e-81,
Organism=Caenorhabditis elegans, GI32564293, Length=683, Percent_Identity=30.4538799414348, Blast_Score=279, Evalue=3e-75,
Organism=Caenorhabditis elegans, GI17552866, Length=422, Percent_Identity=37.6777251184834, Blast_Score=254, Evalue=9e-68,
Organism=Caenorhabditis elegans, GI32565321, Length=399, Percent_Identity=25.5639097744361, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17555296, Length=376, Percent_Identity=26.063829787234, Blast_Score=79, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17537549, Length=360, Percent_Identity=23.6111111111111, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI86570094, Length=337, Percent_Identity=22.8486646884273, Blast_Score=67, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6323844, Length=515, Percent_Identity=34.9514563106796, Blast_Score=303, Evalue=5e-83,
Organism=Saccharomyces cerevisiae, GI6324217, Length=325, Percent_Identity=24, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24646066, Length=629, Percent_Identity=35.1351351351351, Blast_Score=338, Evalue=9e-93,
Organism=Drosophila melanogaster, GI24664226, Length=398, Percent_Identity=38.6934673366834, Blast_Score=262, Evalue=6e-70,
Organism=Drosophila melanogaster, GI62472181, Length=398, Percent_Identity=38.6934673366834, Blast_Score=260, Evalue=2e-69,
Organism=Drosophila melanogaster, GI24664230, Length=398, Percent_Identity=38.6934673366834, Blast_Score=260, Evalue=3e-69,
Organism=Drosophila melanogaster, GI21358123, Length=353, Percent_Identity=36.8271954674221, Blast_Score=198, Evalue=8e-51,
Organism=Drosophila melanogaster, GI24584994, Length=399, Percent_Identity=25.31328320802, Blast_Score=90, Evalue=6e-18,
Organism=Drosophila melanogaster, GI21355075, Length=404, Percent_Identity=23.7623762376238, Blast_Score=75, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004589
- InterPro:   IPR006293
- InterPro:   IPR002121
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR010997
- InterPro:   IPR018982 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF00570 HRDC; PF09382 RQC [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 68306; Mature: 68306

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: PS50967 HRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVPDVSPLPSPGSPLPSPGSPCADAVSADPARVLLADIWGFKDFRPGQEAIIRAVLGGED
CCCCCCCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCC
VLAVMPTGSGKSLCYQLPALMRQGVTLVVSPLIALMRDQVAQLDALGVAAGALNSSIDMD
EEEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
GYRRVMDGLRGGRLKLLYVAPERLARPDTLSLLRDSGVTALAIDEAHCVSQWGHDFRPDY
HHHHHHHHCCCCCEEEEEECHHHHCCCHHHHHHHCCCCEEEEECHHHHHHHCCCCCCCCE
LCLGKVREDLGGVQTVAFTATADAATRDDIAGRLFPAPPRLFIGGFDRPNLRLAMRPKGD
EEHHHHHHHCCCCEEEEEEECCCCCCHHHCCCCCCCCCCCEEECCCCCCCCEEEECCCCH
TRRRMFEFVAAHTGESGVIYCGSRARTEELAEGLRGAGHRALPYHAGLDKPVRDANQDAF
HHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHCCCCCCE
LAEDGLVMVATVAFGMGIDKPDVRFVCHADMPRSIEAYYQEIGRAGRDGLAADTLTFYGL
EECCCEEEEEHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCEEEECC
DDVRLHRMRIEESQAGDEQKRVEIQRLNALLALCEAPRCRRQTLLGYFGERTEPCGNCDL
CHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCHH
CINGVESFDGTIEAQKAMSAMLRTGQRFATEHLINILVGTQTDAITQYGHDKLPTFGVGK
EECCHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCC
DHTRNVWRSIFRQISAGGLISLDIANHGRWLMTEAGRAVLRGQAGVALRSDVLEAAGRGE
HHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEHHCHHHHCCCCCHHHHHHHHHHHCCCC
RKDKERRASAPAVQLEADDRALFDALRAKRQELARAENVPAYVVFADRTLIELATKRPPS
CHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHCCCCC
LDAMREIHGIGQSKLARYGAAFLEVITAG
HHHHHHHHCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVPDVSPLPSPGSPLPSPGSPCADAVSADPARVLLADIWGFKDFRPGQEAIIRAVLGGED
CCCCCCCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCC
VLAVMPTGSGKSLCYQLPALMRQGVTLVVSPLIALMRDQVAQLDALGVAAGALNSSIDMD
EEEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
GYRRVMDGLRGGRLKLLYVAPERLARPDTLSLLRDSGVTALAIDEAHCVSQWGHDFRPDY
HHHHHHHHCCCCCEEEEEECHHHHCCCHHHHHHHCCCCEEEEECHHHHHHHCCCCCCCCE
LCLGKVREDLGGVQTVAFTATADAATRDDIAGRLFPAPPRLFIGGFDRPNLRLAMRPKGD
EEHHHHHHHCCCCEEEEEEECCCCCCHHHCCCCCCCCCCCEEECCCCCCCCEEEECCCCH
TRRRMFEFVAAHTGESGVIYCGSRARTEELAEGLRGAGHRALPYHAGLDKPVRDANQDAF
HHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHCCCCCCE
LAEDGLVMVATVAFGMGIDKPDVRFVCHADMPRSIEAYYQEIGRAGRDGLAADTLTFYGL
EECCCEEEEEHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCEEEECC
DDVRLHRMRIEESQAGDEQKRVEIQRLNALLALCEAPRCRRQTLLGYFGERTEPCGNCDL
CHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCHH
CINGVESFDGTIEAQKAMSAMLRTGQRFATEHLINILVGTQTDAITQYGHDKLPTFGVGK
EECCHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCC
DHTRNVWRSIFRQISAGGLISLDIANHGRWLMTEAGRAVLRGQAGVALRSDVLEAAGRGE
HHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEHHCHHHHCCCCCHHHHHHHHHHHCCCC
RKDKERRASAPAVQLEADDRALFDALRAKRQELARAENVPAYVVFADRTLIELATKRPPS
CHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHCCCCC
LDAMREIHGIGQSKLARYGAAFLEVITAG
HHHHHHHHCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3027506; 1379743; 9278503; 2164680 [H]