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The map label for this gene is engD [H]

Identifier: 83313445

GI number: 83313445

Start: 4751330

End: 4752433

Strand: Reverse

Name: engD [H]

Synonym: amb4346

Alternate gene names: 83313445

Gene position: 4752433-4751330 (Counterclockwise)

Preceding gene: 83313446

Following gene: 83313443

Centisome position: 95.68

GC content: 65.49

Gene sequence:

>1104_bases
ATGGGTTTCAATTGCGGTATCGTCGGCCTGCCCAACGTGGGCAAGAGCACCCTGTTCAACGCCCTGACCTCGACGGCGGC
GGCGCAGGCGGCCAACTACCCCTTCTGCACCATCGAGCCCAATGTGGGCCGCGTGGCGGTGCCCGACCCGCGCCTGGACA
GGCTGGTGGTCATCGGCAAGAGCCAGAAGGAAATCCCCACCCAGCTGGAATTCGTCGACATCGCCGGCCTGGTGCGCGGC
GCCTCCAAGGGTGAGGGCCTGGGCAACCAGTTCCTGGCCAATATCCGCGAGGTGGACGCCATCGTCCACGTGCTGCGCTG
CTTCGAGGACGGCGACATCACCCATGTGGAGGGCTCGGTCGATCCGGTGCGCGATGCCGAGACCATCGAGACCGAACTGA
TGCTGGCCGATCTCGACTCGCTGGAGCGCCGCATCGTCCCCCTGGAGAAGAAGGCCAAGAACGGCGACAAGGAGGCCAAG
GCCCAGGTCGACGTCATGGCCCCGCTGCTGGCTTGCTTGCGCGAAGGCAAGCCCGCCCGCACCATCACCTTCGACACCGA
GGAAGAGCGCCGCATCGCCAAGACCCTGGGCCTGATGACCGTCAAGCCCGTGGTCTACGCCTGCAACGTGGATGAAGCCT
CGGCCGCCACCGGCAACAAGTTCTCCGAAGCGGTTGCCAAGTTCGCCGCCGCCGAGGGCAACAGCTCGGTGGTGATCTCG
GCCGCCATCGAATCCGAGGTGGCCCAACTGGCCTCCGAGGAAGAGCGCAAGGAATTCCTCGAAACCCTGGGGCTGGAAGA
GACGGGCCTCGCCCGCGTCATCCGTGCCGGCTACGAGCTGCTGCACCTCATCACCTTCTTCACCGTCGGCCCCAAGGAAG
CCCGCGCCTGGACCCTGCAGAAGGGCTGCAAGGCCCCCCAGGCGGCCGGCGTCATCCATACCGACTTCGAACGCGGTTTC
ATCCGCGCCGAGACCATCGCCTATGACGACTTCATCGCCTGCAACGGCGAGGCGGGCGCCAAGGAAGCCGGCAAGATGCG
CCTGGAAGGCAAGGAATACGTCGTCCAGGACGGCGACATCTTCCACTTCCTGTTCAACGTTTGA

Upstream 100 bases:

>100_bases
GCCCCCGCTCCGGCCCAAGTTTCCGCTCCGCCGTCGGGCGGCAGCCTCGCCGAGGCGCTGAAGGCGGCCATGACCAAGAT
CATCAGGAAGGACTGAGTCC

Downstream 100 bases:

>100_bases
TTTGTGAATGAAAGGGAGGTCTGGAGGCATCGCCTCCAGCCGGAGTCGGGGCGGGAGCCCCGCTCATCCCAGGAATGCCG
CTCCCGCCAGACACAACCCG

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MGFNCGIVGLPNVGKSTLFNALTSTAAAQAANYPFCTIEPNVGRVAVPDPRLDRLVVIGKSQKEIPTQLEFVDIAGLVRG
ASKGEGLGNQFLANIREVDAIVHVLRCFEDGDITHVEGSVDPVRDAETIETELMLADLDSLERRIVPLEKKAKNGDKEAK
AQVDVMAPLLACLREGKPARTITFDTEEERRIAKTLGLMTVKPVVYACNVDEASAATGNKFSEAVAKFAAAEGNSSVVIS
AAIESEVAQLASEEERKEFLETLGLEETGLARVIRAGYELLHLITFFTVGPKEARAWTLQKGCKAPQAAGVIHTDFERGF
IRAETIAYDDFIACNGEAGAKEAGKMRLEGKEYVVQDGDIFHFLFNV

Sequences:

>Translated_367_residues
MGFNCGIVGLPNVGKSTLFNALTSTAAAQAANYPFCTIEPNVGRVAVPDPRLDRLVVIGKSQKEIPTQLEFVDIAGLVRG
ASKGEGLGNQFLANIREVDAIVHVLRCFEDGDITHVEGSVDPVRDAETIETELMLADLDSLERRIVPLEKKAKNGDKEAK
AQVDVMAPLLACLREGKPARTITFDTEEERRIAKTLGLMTVKPVVYACNVDEASAATGNKFSEAVAKFAAAEGNSSVVIS
AAIESEVAQLASEEERKEFLETLGLEETGLARVIRAGYELLHLITFFTVGPKEARAWTLQKGCKAPQAAGVIHTDFERGF
IRAETIAYDDFIACNGEAGAKEAGKMRLEGKEYVVQDGDIFHFLFNV
>Mature_366_residues
GFNCGIVGLPNVGKSTLFNALTSTAAAQAANYPFCTIEPNVGRVAVPDPRLDRLVVIGKSQKEIPTQLEFVDIAGLVRGA
SKGEGLGNQFLANIREVDAIVHVLRCFEDGDITHVEGSVDPVRDAETIETELMLADLDSLERRIVPLEKKAKNGDKEAKA
QVDVMAPLLACLREGKPARTITFDTEEERRIAKTLGLMTVKPVVYACNVDEASAATGNKFSEAVAKFAAAEGNSSVVISA
AIESEVAQLASEEERKEFLETLGLEETGLARVIRAGYELLHLITFFTVGPKEARAWTLQKGCKAPQAAGVIHTDFERGFI
RAETIAYDDFIACNGEAGAKEAGKMRLEGKEYVVQDGDIFHFLFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=366, Percent_Identity=46.9945355191257, Blast_Score=311, Evalue=5e-85,
Organism=Homo sapiens, GI58761502, Length=233, Percent_Identity=38.6266094420601, Blast_Score=155, Evalue=6e-38,
Organism=Escherichia coli, GI1787454, Length=367, Percent_Identity=59.4005449591281, Blast_Score=429, Evalue=1e-121,
Organism=Escherichia coli, GI1789574, Length=132, Percent_Identity=34.8484848484849, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17509631, Length=369, Percent_Identity=43.9024390243902, Blast_Score=294, Evalue=6e-80,
Organism=Saccharomyces cerevisiae, GI6319499, Length=375, Percent_Identity=40.2666666666667, Blast_Score=276, Evalue=4e-75,
Organism=Saccharomyces cerevisiae, GI6321773, Length=378, Percent_Identity=37.8306878306878, Blast_Score=227, Evalue=2e-60,
Organism=Saccharomyces cerevisiae, GI6321649, Length=344, Percent_Identity=29.0697674418605, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24640873, Length=367, Percent_Identity=46.866485013624, Blast_Score=300, Evalue=1e-81,
Organism=Drosophila melanogaster, GI24640877, Length=367, Percent_Identity=46.866485013624, Blast_Score=300, Evalue=1e-81,
Organism=Drosophila melanogaster, GI24640875, Length=367, Percent_Identity=46.866485013624, Blast_Score=300, Evalue=1e-81,
Organism=Drosophila melanogaster, GI24640879, Length=329, Percent_Identity=44.3768996960486, Blast_Score=247, Evalue=1e-65,
Organism=Drosophila melanogaster, GI24585318, Length=189, Percent_Identity=29.1005291005291, Blast_Score=72, Evalue=7e-13,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 39705; Mature: 39573

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFNCGIVGLPNVGKSTLFNALTSTAAAQAANYPFCTIEPNVGRVAVPDPRLDRLVVIGK
CCCCCCEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEECCCCCCCEEEEECC
SQKEIPTQLEFVDIAGLVRGASKGEGLGNQFLANIREVDAIVHVLRCFEDGDITHVEGSV
CCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCC
DPVRDAETIETELMLADLDSLERRIVPLEKKAKNGDKEAKAQVDVMAPLLACLREGKPAR
CCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCE
TITFDTEEERRIAKTLGLMTVKPVVYACNVDEASAATGNKFSEAVAKFAAAEGNSSVVIS
EEEECCHHHHHHHHHHHHHEECCEEEEECCCHHCCCCCCHHHHHHHHHHHCCCCCCEEEE
AAIESEVAQLASEEERKEFLETLGLEETGLARVIRAGYELLHLITFFTVGPKEARAWTLQ
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
KGCKAPQAAGVIHTDFERGFIRAETIAYDDFIACNGEAGAKEAGKMRLEGKEYVVQDGDI
HCCCCCCCCCCEEECCCCCEEEEEEEEECCEEEECCCCCCCCCCCEEECCCEEEEECCCE
FHFLFNV
EEEEECC
>Mature Secondary Structure 
GFNCGIVGLPNVGKSTLFNALTSTAAAQAANYPFCTIEPNVGRVAVPDPRLDRLVVIGK
CCCCCEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEECCCCCCCEEEEECC
SQKEIPTQLEFVDIAGLVRGASKGEGLGNQFLANIREVDAIVHVLRCFEDGDITHVEGSV
CCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCC
DPVRDAETIETELMLADLDSLERRIVPLEKKAKNGDKEAKAQVDVMAPLLACLREGKPAR
CCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCE
TITFDTEEERRIAKTLGLMTVKPVVYACNVDEASAATGNKFSEAVAKFAAAEGNSSVVIS
EEEECCHHHHHHHHHHHHHEECCEEEEECCCHHCCCCCCHHHHHHHHHHHCCCCCCEEEE
AAIESEVAQLASEEERKEFLETLGLEETGLARVIRAGYELLHLITFFTVGPKEARAWTLQ
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
KGCKAPQAAGVIHTDFERGFIRAETIAYDDFIACNGEAGAKEAGKMRLEGKEYVVQDGDI
HCCCCCCCCCCEEECCCCCEEEEEEEEECCEEEECCCCCCCCCCCEEECCCEEEEECCCE
FHFLFNV
EEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA