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The map label for this gene is adrA [H]

Identifier: 83313443

GI number: 83313443

Start: 4749123

End: 4750190

Strand: Reverse

Name: adrA [H]

Synonym: amb4344

Alternate gene names: 83313443

Gene position: 4750190-4749123 (Counterclockwise)

Preceding gene: 83313445

Following gene: 83313441

Centisome position: 95.63

GC content: 67.98

Gene sequence:

>1068_bases
ATGCGTGATCTGGTTGTGCAAGTGATGGATTCCCGTCTGTCCGCCCTGCTGTCCCAGTGGCGGCAGGCCGAGACGGTGGA
GGGCGATCCCGCCGCCTATTTCGCCGCCCACGCCGATCACCTGCTGGTCATCGAGACCGAGGGCGGCGCCAACCGCTACG
CCCATTACGGCCGCGCCTTCACCGCCTGCTTCGGCCAGGACCTGACCGGGCAGGTCATCGACCTGCTGCCCGCCGACATC
CTGCCCGCTGACCGGCGCTTCATGCTGGAATTCGAGTACGGCTTCGTGCGCCGCACCGGGCGCCCCCTGTGGCGCTCCTA
CACTGCCCTGTTCGGTCAGGACCTGCCGCAGACCTGGCAAAGGCTGGTTCTGCCCGCCGGAAACGGCCGGCTGGTGGTGG
GGGCCTATCCCGTGGATGTCCCGCCGCCGGCGCAAGGGGGCGAGGCGCTGCTGCATCTGGTCATCGACCGGGTGCCGGTG
GTGCTGGCCGAGGATGGCGGCATCGAGGACCTGGCTCTGTCCCTGGGCGCCTTCTGCGATACCAGCCGCCACATGGCCGA
GCTGGAAGAGCTGGCCAGCCGCGATTCCCTGACCCAAACCGCCAATCGCCGCCATTTCGAGCATCTGGCCGGGCTGGAAC
TGGACCACGCCCGGCGCATGGGCCGCTCCTTCGCCCTGCTGGCGCTGGATATCGACCATTTCAAGCGCATCAACGACACC
TGGGGCCACGCCGCCGGGGACGAGGCCCTGAAGGCCTTCGCCAATGCCTGCCGGCTGTCCCTGCGTGAATACGATATTCT
CGGCCGGATTGGCGGCGAGGAATTCGCCGTGGCCCTGCCCAATACCGGCCCCGACGGCGCCCGCGTCATCGCCGAGCGCC
TGCGCGCCGCCGTGGAGGAACTGGTGGTTCGCCCGGCCAAGGGCGAATTGTTCGACCTCACCGTCAGCATCGGCATCGCC
CAGTTGCGTGAAGGCGACCTGACCGTCGAGACCATGTTGGAACGCGCCGATCAGGCCCTCTATCGCGCCAAGAATTCCGG
GCGGAACAGGGTGATGGCGGAGGAATAG

Upstream 100 bases:

>100_bases
CGACACCATACGCAGGTTTCCGATGCCGGTCCAGACCGCCGGGAACTGGTCGAAAGCCTGATCCTGTGATACCAGTAGGG
CATGGCAAGGGTGAGATTCC

Downstream 100 bases:

>100_bases
GGCGAGGAACGCCTTACGGCGTCTCCCGGGCTGCCGCCCGGACCCGCCTGGAGGCGGGGCCTCCAGACCTCCGATCCAAT
GAACAGGGATGCGCGAAGGG

Product: response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MRDLVVQVMDSRLSALLSQWRQAETVEGDPAAYFAAHADHLLVIETEGGANRYAHYGRAFTACFGQDLTGQVIDLLPADI
LPADRRFMLEFEYGFVRRTGRPLWRSYTALFGQDLPQTWQRLVLPAGNGRLVVGAYPVDVPPPAQGGEALLHLVIDRVPV
VLAEDGGIEDLALSLGAFCDTSRHMAELEELASRDSLTQTANRRHFEHLAGLELDHARRMGRSFALLALDIDHFKRINDT
WGHAAGDEALKAFANACRLSLREYDILGRIGGEEFAVALPNTGPDGARVIAERLRAAVEELVVRPAKGELFDLTVSIGIA
QLREGDLTVETMLERADQALYRAKNSGRNRVMAEE

Sequences:

>Translated_355_residues
MRDLVVQVMDSRLSALLSQWRQAETVEGDPAAYFAAHADHLLVIETEGGANRYAHYGRAFTACFGQDLTGQVIDLLPADI
LPADRRFMLEFEYGFVRRTGRPLWRSYTALFGQDLPQTWQRLVLPAGNGRLVVGAYPVDVPPPAQGGEALLHLVIDRVPV
VLAEDGGIEDLALSLGAFCDTSRHMAELEELASRDSLTQTANRRHFEHLAGLELDHARRMGRSFALLALDIDHFKRINDT
WGHAAGDEALKAFANACRLSLREYDILGRIGGEEFAVALPNTGPDGARVIAERLRAAVEELVVRPAKGELFDLTVSIGIA
QLREGDLTVETMLERADQALYRAKNSGRNRVMAEE
>Mature_355_residues
MRDLVVQVMDSRLSALLSQWRQAETVEGDPAAYFAAHADHLLVIETEGGANRYAHYGRAFTACFGQDLTGQVIDLLPADI
LPADRRFMLEFEYGFVRRTGRPLWRSYTALFGQDLPQTWQRLVLPAGNGRLVVGAYPVDVPPPAQGGEALLHLVIDRVPV
VLAEDGGIEDLALSLGAFCDTSRHMAELEELASRDSLTQTANRRHFEHLAGLELDHARRMGRSFALLALDIDHFKRINDT
WGHAAGDEALKAFANACRLSLREYDILGRIGGEEFAVALPNTGPDGARVIAERLRAAVEELVVRPAKGELFDLTVSIGIA
QLREGDLTVETMLERADQALYRAKNSGRNRVMAEE

Specific function: Unknown

COG id: COG3706

COG function: function code T; Response regulator containing a CheY-like receiver domain and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1786584, Length=169, Percent_Identity=40.2366863905325, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1787262, Length=189, Percent_Identity=34.9206349206349, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI87081881, Length=167, Percent_Identity=40.7185628742515, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI145693134, Length=174, Percent_Identity=39.0804597701149, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI87082007, Length=178, Percent_Identity=37.0786516853933, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1788381, Length=235, Percent_Identity=31.063829787234, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1787802, Length=171, Percent_Identity=36.2573099415205, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788085, Length=166, Percent_Identity=34.9397590361446, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1787541, Length=309, Percent_Identity=26.537216828479, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1787816, Length=163, Percent_Identity=30.6748466257669, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI87081974, Length=156, Percent_Identity=30.7692307692308, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1788956, Length=168, Percent_Identity=34.5238095238095, Blast_Score=65, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR007894 [H]

Pfam domain/function: PF00990 GGDEF; PF05230 MASE2 [H]

EC number: NA

Molecular weight: Translated: 39210; Mature: 39210

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS50887 GGDEF ; PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDLVVQVMDSRLSALLSQWRQAETVEGDPAAYFAAHADHLLVIETEGGANRYAHYGRAF
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEEECCCEEEEEECCCCCCHHHHHHHHH
TACFGQDLTGQVIDLLPADILPADRRFMLEFEYGFVRRTGRPLWRSYTALFGQDLPQTWQ
HHHHCCCCCHHHHHHCCCCCCCCCCEEEEEECHHHHHHCCCHHHHHHHHHHCCCHHHHHH
RLVLPAGNGRLVVGAYPVDVPPPAQGGEALLHLVIDRVPVVLAEDGGIEDLALSLGAFCD
HHEEECCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHC
TSRHMAELEELASRDSLTQTANRRHFEHLAGLELDHARRMGRSFALLALDIDHFKRINDT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCEEEEEEEHHHHHHHHHH
WGHAAGDEALKAFANACRLSLREYDILGRIGGEEFAVALPNTGPDGARVIAERLRAAVEE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHH
LVVRPAKGELFDLTVSIGIAQLREGDLTVETMLERADQALYRAKNSGRNRVMAEE
HHCCCCCCCEEEEEEEHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MRDLVVQVMDSRLSALLSQWRQAETVEGDPAAYFAAHADHLLVIETEGGANRYAHYGRAF
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEEECCCEEEEEECCCCCCHHHHHHHHH
TACFGQDLTGQVIDLLPADILPADRRFMLEFEYGFVRRTGRPLWRSYTALFGQDLPQTWQ
HHHHCCCCCHHHHHHCCCCCCCCCCEEEEEECHHHHHHCCCHHHHHHHHHHCCCHHHHHH
RLVLPAGNGRLVVGAYPVDVPPPAQGGEALLHLVIDRVPVVLAEDGGIEDLALSLGAFCD
HHEEECCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHC
TSRHMAELEELASRDSLTQTANRRHFEHLAGLELDHARRMGRSFALLALDIDHFKRINDT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCEEEEEEEHHHHHHHHHH
WGHAAGDEALKAFANACRLSLREYDILGRIGGEEFAVALPNTGPDGARVIAERLRAAVEE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHH
LVVRPAKGELFDLTVSIGIAQLREGDLTVETMLERADQALYRAKNSGRNRVMAEE
HHCCCCCCCEEEEEEEHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]