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The map label for this gene is pheA [H]

Identifier: 83313266

GI number: 83313266

Start: 4583384

End: 4584253

Strand: Reverse

Name: pheA [H]

Synonym: amb4167

Alternate gene names: 83313266

Gene position: 4584253-4583384 (Counterclockwise)

Preceding gene: 83313267

Following gene: 83313259

Centisome position: 92.29

GC content: 67.24

Gene sequence:

>870_bases
ATGAACGACCAGCCCAATCCCGATCAGGCTATCGCCTTCCAGGGCGAGCCCGGCGCCTATTCCCATCTGGCTTGCCGCAA
TGCCTATCCCGGCATGCAGCCGCTGCCCTGCGCCACCTTCGAGGACACCTTCGCCGCCGTGCGCGAGGGCCGCGCCCGCT
ATGCCATGATCCCCATCGACAATTCGGTGGCGGGCCGGGTCGCCGACGTGCATCACCTGATGCCCTATGCCGGGCTGCAC
ATCATCGCCGAGCATTTCGAGCGCATCAGCCACCACCTGCTGGTGGTTCCCGGCGCGACGCTCGACACCATCAAGACGGT
GAAAAGCCACGTCCACGCCCTGGGCCAGTGCCGCAACCTGATCCGCGAACTGGGCCTCAAGGTCATCGTCGGCACCGACA
CTGCCGGCGCGGCGGCCGAGCTGGCCGAGCGCCAGGACCCCACCATGGCGGCCATCGCCTCGGAACTGGCGGCCGAGGCC
TATGGCCTGGTGTCGCTGAAGGCGGGGATCGAGGACGCCGAGCACAACACCACCCGCTTCGTGGTCCTGGCCCGCGAGGC
GCTGGAGCCCAATCCCAACCAGCCCTGCGTCACCACCTTCGTGTTCCGGGTGCGCAACGTGGCCGCCGCGCTGTACAAGG
CGCTGGGCGGTTTCGCCACCAACGGCATCAACATGACCCGGCTGGAAAGCTACATGGTGGGCGGCGAATTCGCCGCCACC
CAGTTCTACGCCGACGTGGAAGGCCACCCCACCCAGCGCAATCTGCGTCTGGCCCTGGAGGAACTGGACTTCTTCAGCCA
CGAGGTCCGCATCCTGGGCGTCTATCCCCGCCATCCCTTCCGCATGAAGCAGCAGAGCGGCGCAGAGTAG

Upstream 100 bases:

>100_bases
ATGCGCATCGATTGCGCCTTGGTTGACACGGTTCCGCTGGGTGTCGATACTCCCGCCGACCTCGAACGGGCGCGTGCCCT
GCTGAAAGCCTGAGTCCCGC

Downstream 100 bases:

>100_bases
GTCACAGCCCTTCCAGGATCACCACGGTGCGCCGCGCCGAGCGGTGGCTGAGGCCGACGATGGCTTGGTATTCGGGGGAG
TCCAGGCAGGCCCTGGCGGT

Product: prephenate dehydratase

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MNDQPNPDQAIAFQGEPGAYSHLACRNAYPGMQPLPCATFEDTFAAVREGRARYAMIPIDNSVAGRVADVHHLMPYAGLH
IIAEHFERISHHLLVVPGATLDTIKTVKSHVHALGQCRNLIRELGLKVIVGTDTAGAAAELAERQDPTMAAIASELAAEA
YGLVSLKAGIEDAEHNTTRFVVLAREALEPNPNQPCVTTFVFRVRNVAAALYKALGGFATNGINMTRLESYMVGGEFAAT
QFYADVEGHPTQRNLRLALEELDFFSHEVRILGVYPRHPFRMKQQSGAE

Sequences:

>Translated_289_residues
MNDQPNPDQAIAFQGEPGAYSHLACRNAYPGMQPLPCATFEDTFAAVREGRARYAMIPIDNSVAGRVADVHHLMPYAGLH
IIAEHFERISHHLLVVPGATLDTIKTVKSHVHALGQCRNLIRELGLKVIVGTDTAGAAAELAERQDPTMAAIASELAAEA
YGLVSLKAGIEDAEHNTTRFVVLAREALEPNPNQPCVTTFVFRVRNVAAALYKALGGFATNGINMTRLESYMVGGEFAAT
QFYADVEGHPTQRNLRLALEELDFFSHEVRILGVYPRHPFRMKQQSGAE
>Mature_289_residues
MNDQPNPDQAIAFQGEPGAYSHLACRNAYPGMQPLPCATFEDTFAAVREGRARYAMIPIDNSVAGRVADVHHLMPYAGLH
IIAEHFERISHHLLVVPGATLDTIKTVKSHVHALGQCRNLIRELGLKVIVGTDTAGAAAELAERQDPTMAAIASELAAEA
YGLVSLKAGIEDAEHNTTRFVVLAREALEPNPNQPCVTTFVFRVRNVAAALYKALGGFATNGINMTRLESYMVGGEFAAT
QFYADVEGHPTQRNLRLALEELDFFSHEVRILGVYPRHPFRMKQQSGAE

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=280, Percent_Identity=35, Blast_Score=150, Evalue=7e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010952
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 31587; Mature: 31587

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS00857 PREPHENATE_DEHYDR_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDQPNPDQAIAFQGEPGAYSHLACRNAYPGMQPLPCATFEDTFAAVREGRARYAMIPID
CCCCCCCCCEEEEECCCCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEECC
NSVAGRVADVHHLMPYAGLHIIAEHFERISHHLLVVPGATLDTIKTVKSHVHALGQCRNL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHHHH
IRELGLKVIVGTDTAGAAAELAERQDPTMAAIASELAAEAYGLVSLKAGIEDAEHNTTRF
HHHCCCEEEEECCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHEEEECCCCCCCCCCEEE
VVLAREALEPNPNQPCVTTFVFRVRNVAAALYKALGGFATNGINMTRLESYMVGGEFAAT
EEEEHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHCCCCHHHH
QFYADVEGHPTQRNLRLALEELDFFSHEVRILGVYPRHPFRMKQQSGAE
EEEECCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MNDQPNPDQAIAFQGEPGAYSHLACRNAYPGMQPLPCATFEDTFAAVREGRARYAMIPID
CCCCCCCCCEEEEECCCCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEECC
NSVAGRVADVHHLMPYAGLHIIAEHFERISHHLLVVPGATLDTIKTVKSHVHALGQCRNL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHHHH
IRELGLKVIVGTDTAGAAAELAERQDPTMAAIASELAAEAYGLVSLKAGIEDAEHNTTRF
HHHCCCEEEEECCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHEEEECCCCCCCCCCEEE
VVLAREALEPNPNQPCVTTFVFRVRNVAAALYKALGGFATNGINMTRLESYMVGGEFAAT
EEEEHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHCCCCHHHH
QFYADVEGHPTQRNLRLALEELDFFSHEVRILGVYPRHPFRMKQQSGAE
EEEECCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]