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The map label for this gene is kdsB

Identifier: 83313267

GI number: 83313267

Start: 4584261

End: 4585001

Strand: Reverse

Name: kdsB

Synonym: amb4168

Alternate gene names: 83313267

Gene position: 4585001-4584261 (Counterclockwise)

Preceding gene: 83313270

Following gene: 83313266

Centisome position: 92.31

GC content: 69.1

Gene sequence:

>741_bases
ATGGCCGAACTCACCCCCATCATCGTCATTCCCGCCCGCATGCAGGCCACCCGGCTGCCGGGCAAGCCCCTGGCCGACAT
CCATGGCGAGCCGATGATCATCCATGTCTGGCGCCGCTCGGTGCAGGCCGGGCTTGGCCCCGTGGTGGTGGCCTGCTCGG
AGGCCGAGGTGTTCGATGCGGTGCACGCCCATGGCGGCCAGGCTGTGATGACCGACCCCGACCATCCGTCCGGCTCGGAC
CGGGTGTGGGAGGCGGTGCGCAAGCTCGACCCCGAGGGCCGGTTCGATGCCATCGTCAACGTGCAGGGCGACCTTCCCAC
CCTGGACCCCCAGATCATCCGCGCCGTCTTCGCGCCTCTGGCCGAGCCGGGGGTCGACGTCGCCACCCTGGTGACCGAGA
TCACCAACGAGGAGGAGCGCACCAACCCCAACGTGGTCAAGGCGGTGGTGGGGCTGCGTCCCGGCCAGCGCGTGGGCCGG
GCGCTCTATTTCAGCCGCGCCACCGTGCCGGCCAATGCGGGGCCGCACTATCATCACATCGGGCTCTACGCCTATCGCCG
GGACTCGCTCGAGCGCTTCGTCAGCCTGCCCCAGGGCGTGCTGGAAAGCCGCGAGAAGCTGGAGCAGTTGCGGGCGCTGG
AGAATGGCATGCGCATCGATTGCGCCTTGGTTGACACGGTTCCGCTGGGTGTCGATACTCCCGCCGACCTCGAACGGGCG
CGTGCCCTGCTGAAAGCCTGA

Upstream 100 bases:

>100_bases
TTTGTCGTTTCCGTGCCGTTGCGACGCGCCCGAGTGTGGCGCGAAATGGCGGATGTGGATAGGGTGCGTATTAACTAGCT
GATACACACACGGATCACCC

Downstream 100 bases:

>100_bases
GTCCCGCATGAACGACCAGCCCAATCCCGATCAGGCTATCGCCTTCCAGGGCGAGCCCGGCGCCTATTCCCATCTGGCTT
GCCGCAATGCCTATCCCGGC

Product: 3-deoxy-manno-octulosonate cytidylyltransferase

Products: NA

Alternate protein names: CMP-2-keto-3-deoxyoctulosonic acid synthase; CKS; CMP-KDO synthase

Number of amino acids: Translated: 246; Mature: 245

Protein sequence:

>246_residues
MAELTPIIVIPARMQATRLPGKPLADIHGEPMIIHVWRRSVQAGLGPVVVACSEAEVFDAVHAHGGQAVMTDPDHPSGSD
RVWEAVRKLDPEGRFDAIVNVQGDLPTLDPQIIRAVFAPLAEPGVDVATLVTEITNEEERTNPNVVKAVVGLRPGQRVGR
ALYFSRATVPANAGPHYHHIGLYAYRRDSLERFVSLPQGVLESREKLEQLRALENGMRIDCALVDTVPLGVDTPADLERA
RALLKA

Sequences:

>Translated_246_residues
MAELTPIIVIPARMQATRLPGKPLADIHGEPMIIHVWRRSVQAGLGPVVVACSEAEVFDAVHAHGGQAVMTDPDHPSGSD
RVWEAVRKLDPEGRFDAIVNVQGDLPTLDPQIIRAVFAPLAEPGVDVATLVTEITNEEERTNPNVVKAVVGLRPGQRVGR
ALYFSRATVPANAGPHYHHIGLYAYRRDSLERFVSLPQGVLESREKLEQLRALENGMRIDCALVDTVPLGVDTPADLERA
RALLKA
>Mature_245_residues
AELTPIIVIPARMQATRLPGKPLADIHGEPMIIHVWRRSVQAGLGPVVVACSEAEVFDAVHAHGGQAVMTDPDHPSGSDR
VWEAVRKLDPEGRFDAIVNVQGDLPTLDPQIIRAVFAPLAEPGVDVATLVTEITNEEERTNPNVVKAVVGLRPGQRVGRA
LYFSRATVPANAGPHYHHIGLYAYRRDSLERFVSLPQGVLESREKLEQLRALENGMRIDCALVDTVPLGVDTPADLERAR
ALLKA

Specific function: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria

COG id: COG1212

COG function: function code M; CMP-2-keto-3-deoxyoctulosonic acid synthetase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsB family

Homologues:

Organism=Escherichia coli, GI1787147, Length=254, Percent_Identity=43.7007874015748, Blast_Score=178, Evalue=3e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KDSB_MAGSA (Q2VZK3)

Other databases:

- EMBL:   AP007255
- RefSeq:   YP_423531.1
- ProteinModelPortal:   Q2VZK3
- STRING:   Q2VZK3
- GeneID:   3803539
- GenomeReviews:   AP007255_GR
- KEGG:   mag:amb4168
- NMPDR:   fig|342108.5.peg.3748
- eggNOG:   COG1212
- HOGENOM:   HBG637773
- OMA:   IIPARLK
- PhylomeDB:   Q2VZK3
- ProtClustDB:   PRK05450
- BioCyc:   MMAG342108:AMB4168-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00057
- InterPro:   IPR003329
- InterPro:   IPR004528
- TIGRFAMs:   TIGR00466

Pfam domain/function: PF02348 CTP_transf_3

EC number: =2.7.7.38

Molecular weight: Translated: 26795; Mature: 26664

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAELTPIIVIPARMQATRLPGKPLADIHGEPMIIHVWRRSVQAGLGPVVVACSEAEVFDA
CCCCCEEEEECCCHHHHCCCCCCCHHCCCCCEEEHHHHHHHHCCCCCEEEEECCHHHHHH
VHAHGGQAVMTDPDHPSGSDRVWEAVRKLDPEGRFDAIVNVQGDLPTLDPQIIRAVFAPL
HHHCCCEEEEECCCCCCCCHHHHHHHHHCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHH
AEPGVDVATLVTEITNEEERTNPNVVKAVVGLRPGQRVGRALYFSRATVPANAGPHYHHI
CCCCCHHHHHHHHHHCCHHCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCEEEE
GLYAYRRDSLERFVSLPQGVLESREKLEQLRALENGMRIDCALVDTVPLGVDTPADLERA
EEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCHHHHHH
RALLKA
HHHHCC
>Mature Secondary Structure 
AELTPIIVIPARMQATRLPGKPLADIHGEPMIIHVWRRSVQAGLGPVVVACSEAEVFDA
CCCCEEEEECCCHHHHCCCCCCCHHCCCCCEEEHHHHHHHHCCCCCEEEEECCHHHHHH
VHAHGGQAVMTDPDHPSGSDRVWEAVRKLDPEGRFDAIVNVQGDLPTLDPQIIRAVFAPL
HHHCCCEEEEECCCCCCCCHHHHHHHHHCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHH
AEPGVDVATLVTEITNEEERTNPNVVKAVVGLRPGQRVGRALYFSRATVPANAGPHYHHI
CCCCCHHHHHHHHHHCCHHCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCEEEE
GLYAYRRDSLERFVSLPQGVLESREKLEQLRALENGMRIDCALVDTVPLGVDTPADLERA
EEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCHHHHHH
RALLKA
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA