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The map label for this gene is rsbP [H]

Identifier: 83311758

GI number: 83311758

Start: 2849843

End: 2851015

Strand: Reverse

Name: rsbP [H]

Synonym: amb2659

Alternate gene names: 83311758

Gene position: 2851015-2849843 (Counterclockwise)

Preceding gene: 83311760

Following gene: 83311755

Centisome position: 57.4

GC content: 65.56

Gene sequence:

>1173_bases
TTGGATCAGCAAGAAGAACTCGCCGTCGACTTGGCCCAGGCCAAGGTTCTTGTTGTCGAGGACAACGAGATGAACCGCAT
CTTCGCCTGCGCCGTGCTGGAGAGCATGGGCCTGACCAATGTGGAATGCGCCCGCGATGGCCGCGAGGGTCTGGAGAAGG
TCGAGAGCTTCGCCCCCGACATCGTGCTGCTGGACCTGATGATGCCGGTGATGAACGGCGAGCAATTCCTGGTGGCGCTG
CGCGCCGATCCGCGTTACCGCGCCCTGCCGGTTCTGGTTCTGTCGGCGGTGATCGACCAGACCACCCGCAATGCCTTGTT
CGCCGCCGGGGCCAACGACTATATCGGCAAGCCCATCGACCGTCGGGAACTGGTGGCGCGGGTCGAGGTCCATTTGCGCA
GCCACCTGCTGCTGGCCGACCTGCGGCGCTACCGCGACCGGCTGGCGGTGGACCTGCGCATGGCCAGCGGCATGCAGAAC
GCCCTGTTGCCCGGCCCCGCCCAGATGCGCGAGGCGCGGGACCGCTATGGCCTGTCCATCAATGCGGTGTTCAATCCCTC
CACCGAACTGGGTGGCGATCTGTGGGGGCTGGTGCCGGTGGACGACCATCGCCTTGCCCTTTACACGGTGGACTTCTCCG
GCCACGGCGTCGCCGCCTCCATCAACACCTTCCGCCTGCATCTGCTGTTGCAGGATCTGGATGCCCAGATGGGCTTTCCC
GATGCCGTGCTGGAGAAGGTCAACGTTACCCTGAAGCAATTGCTGCCGCGCGGCCAGTTCGCCACCATGACCCTGGTGGT
GATCGACCGCCAGGAACGGACCCTGTCCCTGGTCAATGCCGGCGGCCCAGCCCCCATTCTGGTGGAGCCGGGTGGAGAGC
CACATCTGGTGGGGGGGGTGGGACTGCCGTTGGGAATCAGCCTGGAGGCCCGGTACGAGCTTGTGACGATGCCGTTCCCG
CCGGGGAGCCAACTTTCGCTTTACAGCGACGCCCTGATCGATGCCCCGGATTCGCACGGCAACCCGCTGGGCGAGGATTG
GGTGCTGGATCTTGTCCGTCAGGTGCTGACCGACGACCCCACCGAGACGGTGGCCGGGGTGATGTCGGTGTTCACCTCCC
GCTCGCCCGGCGAATTCGCCGACGACGTCACTTGGGTTCAGGTGGTGGGCTGA

Upstream 100 bases:

>100_bases
AAGGTTTTGTTGCCGGCCCGGCGGAATTTACTGGTGCAGCCCGTCTTCTTCACTGGCGATTTTCCCAGGCATGGATATCC
TTGGCGACAAGGAGGACGCA

Downstream 100 bases:

>100_bases
GGCGCCGGCAGGCGGAAGCGCATGGTGATGCGGCGTCCCCGATCGGTGAACAGCACCCGTTCGCACAGGGCGCGGATCTG
GCCGATGCCCCGGCCGGAAC

Product: Serine phosphatase RsbU

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MDQQEELAVDLAQAKVLVVEDNEMNRIFACAVLESMGLTNVECARDGREGLEKVESFAPDIVLLDLMMPVMNGEQFLVAL
RADPRYRALPVLVLSAVIDQTTRNALFAAGANDYIGKPIDRRELVARVEVHLRSHLLLADLRRYRDRLAVDLRMASGMQN
ALLPGPAQMREARDRYGLSINAVFNPSTELGGDLWGLVPVDDHRLALYTVDFSGHGVAASINTFRLHLLLQDLDAQMGFP
DAVLEKVNVTLKQLLPRGQFATMTLVVIDRQERTLSLVNAGGPAPILVEPGGEPHLVGGVGLPLGISLEARYELVTMPFP
PGSQLSLYSDALIDAPDSHGNPLGEDWVLDLVRQVLTDDPTETVAGVMSVFTSRSPGEFADDVTWVQVVG

Sequences:

>Translated_390_residues
MDQQEELAVDLAQAKVLVVEDNEMNRIFACAVLESMGLTNVECARDGREGLEKVESFAPDIVLLDLMMPVMNGEQFLVAL
RADPRYRALPVLVLSAVIDQTTRNALFAAGANDYIGKPIDRRELVARVEVHLRSHLLLADLRRYRDRLAVDLRMASGMQN
ALLPGPAQMREARDRYGLSINAVFNPSTELGGDLWGLVPVDDHRLALYTVDFSGHGVAASINTFRLHLLLQDLDAQMGFP
DAVLEKVNVTLKQLLPRGQFATMTLVVIDRQERTLSLVNAGGPAPILVEPGGEPHLVGGVGLPLGISLEARYELVTMPFP
PGSQLSLYSDALIDAPDSHGNPLGEDWVLDLVRQVLTDDPTETVAGVMSVFTSRSPGEFADDVTWVQVVG
>Mature_390_residues
MDQQEELAVDLAQAKVLVVEDNEMNRIFACAVLESMGLTNVECARDGREGLEKVESFAPDIVLLDLMMPVMNGEQFLVAL
RADPRYRALPVLVLSAVIDQTTRNALFAAGANDYIGKPIDRRELVARVEVHLRSHLLLADLRRYRDRLAVDLRMASGMQN
ALLPGPAQMREARDRYGLSINAVFNPSTELGGDLWGLVPVDDHRLALYTVDFSGHGVAASINTFRLHLLLQDLDAQMGFP
DAVLEKVNVTLKQLLPRGQFATMTLVVIDRQERTLSLVNAGGPAPILVEPGGEPHLVGGVGLPLGISLEARYELVTMPFP
PGSQLSLYSDALIDAPDSHGNPLGEDWVLDLVRQVLTDDPTETVAGVMSVFTSRSPGEFADDVTWVQVVG

Specific function: Positive regulator of sigma-B activity. Dephosphorylates rsbV in response to energy stress [H]

COG id: COG2208

COG function: function code TK; Serine phosphatase RsbU, regulator of sigma subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=119, Percent_Identity=37.8151260504202, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1786911, Length=122, Percent_Identity=38.5245901639344, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI87082012, Length=121, Percent_Identity=34.7107438016529, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788191, Length=106, Percent_Identity=36.7924528301887, Blast_Score=63, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=128, Percent_Identity=30.46875, Blast_Score=63, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR001932
- InterPro:   IPR010822 [H]

Pfam domain/function: PF00989 PAS; PF07228 SpoIIE [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 42592; Mature: 42592

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQQEELAVDLAQAKVLVVEDNEMNRIFACAVLESMGLTNVECARDGREGLEKVESFAPD
CCCHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCC
IVLLDLMMPVMNGEQFLVALRADPRYRALPVLVLSAVIDQTTRNALFAAGANDYIGKPID
HHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCEEEECCCCCCCCCCCC
RRELVARVEVHLRSHLLLADLRRYRDRLAVDLRMASGMQNALLPGPAQMREARDRYGLSI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHCCCCCCCCCCHHHHHHHHHHHCEEE
NAVFNPSTELGGDLWGLVPVDDHRLALYTVDFSGHGVAASINTFRLHLLLQDLDAQMGFP
EEEECCCHHCCCCEEEEEECCCCEEEEEEEEECCCCEEEEHHHEEEEHHHHHHHHCCCCC
DAVLEKVNVTLKQLLPRGQFATMTLVVIDRQERTLSLVNAGGPAPILVEPGGEPHLVGGV
HHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCEEEEEECCCCCCEEECCCCCCEEEECC
GLPLGISLEARYELVTMPFPPGSQLSLYSDALIDAPDSHGNPLGEDWVLDLVRQVLTDDP
CCCEEEEEEEEEEEEEECCCCCCCEEEEHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCC
TETVAGVMSVFTSRSPGEFADDVTWVQVVG
HHHHHHHHHHHHCCCCCCCCCCCEEEEEEC
>Mature Secondary Structure
MDQQEELAVDLAQAKVLVVEDNEMNRIFACAVLESMGLTNVECARDGREGLEKVESFAPD
CCCHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCC
IVLLDLMMPVMNGEQFLVALRADPRYRALPVLVLSAVIDQTTRNALFAAGANDYIGKPID
HHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCEEEECCCCCCCCCCCC
RRELVARVEVHLRSHLLLADLRRYRDRLAVDLRMASGMQNALLPGPAQMREARDRYGLSI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHCCCCCCCCCCHHHHHHHHHHHCEEE
NAVFNPSTELGGDLWGLVPVDDHRLALYTVDFSGHGVAASINTFRLHLLLQDLDAQMGFP
EEEECCCHHCCCCEEEEEECCCCEEEEEEEEECCCCEEEEHHHEEEEHHHHHHHHCCCCC
DAVLEKVNVTLKQLLPRGQFATMTLVVIDRQERTLSLVNAGGPAPILVEPGGEPHLVGGV
HHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCEEEEEECCCCCCEEECCCCCCEEEECC
GLPLGISLEARYELVTMPFPPGSQLSLYSDALIDAPDSHGNPLGEDWVLDLVRQVLTDDP
CCCEEEEEEEEEEEEEECCCCCCCEEEEHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCC
TETVAGVMSVFTSRSPGEFADDVTWVQVVG
HHHHHHHHHHHHCCCCCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 10632888 [H]